Sequencing of longitudinal glioma pairs
Clonal evolution drives cancer progression and therapeutic resistance. Recent studies revealed divergent longitudinal trajectories in gliomas, but early molecular traits steering post-treatment cancer evolution remain unclear. We analyzed sequencing data of 544 initial-recurrent adult diffuse glioma pairs to identify genomic and transcriptomic early predictors of tumor evolution in each molecular subtype.
- 366 samples
- DAC: EGAC00001003019
- Technology: Illumina NovaSeq 6000
The Asian Glioma Genomic Atlas is a precision neuro-oncology collaboration between China and Korea, aiming to create a comprehensive framework to study RNA sequencing, DNA sequencing, imaging, clinical and drug-screening data.
NA for now
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
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