WGS of off-target analysis of base editing in organoids
Seven clonal organoid lines and one bulk wild-type control sample were paired-end whole-genome sequenced using the Illumina Novaseq 6000 system. We sequenced four clonal intestinal organoid lines harbouring engineered TP53 and FBXW7 mutations as well as three lines targeted for oncogenic APC/TP53/PIK3CA/SMAD4 mutations. The reads were mapped to hg38 genome assembly and data is provided as BAM files.
- 8 samples
- DAC: EGAC00001001864
- Technology: Illumina NovaSeq 6000
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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| Other |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00007837008 | 1671606921294 | 23.3 GB | ||
| EGAF00007837009 | 1671658221341 | 31.5 GB | ||
| EGAF00007837010 | 1671627621714 | 27.4 GB | ||
| EGAF00007837011 | 1671644723473 | 28.3 GB | ||
| EGAF00007837012 | 1671615021233 | 27.3 GB | ||
| EGAF00007837013 | 1671602421053 | 28.2 GB | ||
| EGAF00007837014 | 1671590721108 | 25.5 GB | ||
| EGAF00007837015 | 1671605121212 | 25.3 GB | ||
| 8 Files (216.8 GB) | ||||