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COVID-19 progression and resolution in common variable immunodeficiency patients

116,958 single-cell transcriptomes from samples of peripheral blood mononuclear cells (PBMCs) from five CVID patients at three distinct stages of the SARS-CoV-2 infection: 1) baseline, before viral infection, 2) progression, during viral infection, and 3) convalescence, once the viral infection had been resolved and the patient was PCR negative. CVID patients were under regular immunoglobulin replacement therapy and displayed only mild symptoms during SARS-CoV-2 infection.

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Wellcome Trust Sanger Institute Data Sharing Policy

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005415091 1628189945744 14.1 GB
EGAF00005415092 1628192647717 10.0 GB
EGAF00005415093 1628199610033 12.4 GB
EGAF00005415094 1628179330370 13.7 GB
EGAF00005415107 1628179330370 2.5 GB
EGAF00005415108 1628178584922 2.6 GB
EGAF00005415109 1628179330370 1.7 GB
EGAF00005415110 1628177642895 3.4 GB
EGAF00005415123 1628178584922 1.8 GB
EGAF00005415124 1628180035668 1.9 GB
EGAF00005415125 1628180673562 1.9 GB
EGAF00005415126 1628180035668 1.8 GB
EGAF00005415127 1628178584922 11.5 GB
EGAF00005415128 1628178584922 9.7 GB
EGAF00005415129 1628203404694 15.6 GB
EGAF00005415130 1628194606732 15.2 GB
EGAF00005415131 1628178584922 7.8 GB
EGAF00005415132 1628181845528 6.6 GB
EGAF00005415133 1628180673561 13.5 GB
EGAF00005415134 1628179330370 9.7 GB
EGAF00005415139 1628179330370 3.1 GB
EGAF00005415141 1628180035669 3.1 GB
EGAF00005415143 1628178584922 3.0 GB
EGAF00005415145 1628181282060 2.8 GB
EGAF00005415147 1628180673561 2.3 GB
EGAF00005415148 1628180673561 2.8 GB
EGAF00005415149 1628179330370 2.7 GB
EGAF00005415150 1628180035669 1.6 GB
EGAF00005415159 1628178584922 1.2 GB
EGAF00005415160 1628180035669 2.2 GB
EGAF00005415161 1628178584922 1.6 GB
EGAF00005415162 1628178584922 732.1 MB
EGAF00005415163 1628178584922 1.7 GB
EGAF00005415164 1628179330370 2.0 GB
EGAF00005415165 1628178584922 1.5 GB
EGAF00005415166 1628178584922 1.5 GB
EGAF00005415188 1628212378849 14.7 GB
EGAF00005415190 1628183233162 15.9 GB
EGAF00005415192 1628184848314 13.7 GB
EGAF00005415194 1628183233161 12.9 GB
EGAF00005415203 1628182573796 3.9 GB
EGAF00005415204 1628181845528 3.0 GB
EGAF00005415205 1628182573795 4.1 GB
EGAF00005415206 1628176833356 3.2 GB
EGAF00005415219 1628178584922 2.1 GB
EGAF00005415220 1628176100054 1.7 GB
EGAF00005415221 1628180035668 1.6 GB
EGAF00005415222 1628180673561 1.4 GB
EGAF00005415223 1628192647717 11.6 GB
EGAF00005415224 1628184848314 15.4 GB
EGAF00005415225 1628182573795 9.7 GB
EGAF00005415226 1628182573795 12.7 GB
EGAF00005415231 1628184224008 9.0 GB
EGAF00005415232 1628184224008 16.7 GB
EGAF00005415233 1628186675945 12.7 GB
EGAF00005415234 1628183233161 8.1 GB
EGAF00005415239 1628180673561 4.4 GB
EGAF00005415240 1628179330370 3.8 GB
EGAF00005415241 1628181845528 4.6 GB
EGAF00005415242 1628179330370 3.2 GB
EGAF00005415247 1628180035668 4.4 GB
EGAF00005415248 1628176100054 4.4 GB
EGAF00005415249 1628180673561 5.5 GB
EGAF00005415250 1628180035668 3.9 GB
EGAF00005415255 1628176100054 2.4 GB
EGAF00005415256 1628178584922 2.5 GB
EGAF00005415257 1628182573795 2.2 GB
EGAF00005415258 1628177642895 1.4 GB
EGAF00005415259 1628176833356 1.2 GB
EGAF00005415260 1628178584922 1.6 GB
EGAF00005415261 1628177642895 2.2 GB
EGAF00005415262 1628180035668 2.3 GB
EGAF00007779950 1669379427372 757.7 MB
EGAF00007779951 1669379427372 742.1 MB
EGAF00007779952 1669380349913 1.7 GB
EGAF00007779953 1669384829871 1.8 GB
EGAF00007779954 1669383047491 2.7 GB
EGAF00007779955 1669380349913 2.7 GB
EGAF00007779956 1669381228155 5.4 GB
EGAF00007779957 1669389325860 5.3 GB
EGAF00007779958 1669382126522 11.1 GB
EGAF00007779959 1669385726263 10.8 GB
EGAF00007779960 1669380349913 767.4 MB
EGAF00007779961 1669380349913 757.1 MB
EGAF00007779962 1669381228155 1.8 GB
EGAF00007779963 1669379427372 1.8 GB
EGAF00007779964 1669380349913 861.8 MB
EGAF00007779965 1669378528005 842.9 MB
EGAF00007779966 1669379427373 1.8 GB
EGAF00007779967 1669381228155 1.8 GB
EGAF00007779968 1669382126522 2.5 GB
EGAF00007779969 1669379427373 2.5 GB
EGAF00007779970 1669380349913 4.5 GB
EGAF00007779971 1669383047491 4.4 GB
EGAF00007779972 1669379427372 14.9 GB
EGAF00007779973 1669393821383 14.6 GB
EGAF00007779974 1669381228155 636.3 MB
EGAF00007779975 1669383047491 627.1 MB
EGAF00007779976 1669384829871 1.8 GB
EGAF00007779977 1669380349913 1.8 GB
EGAF00007779978 1669381228155 896.6 MB
EGAF00007779979 1669378528005 882.1 MB
EGAF00007779980 1669379427372 2.4 GB
EGAF00007779981 1669380349913 2.4 GB
EGAF00007779982 1669379427372 2.0 GB
EGAF00007779983 1669378528005 2.0 GB
EGAF00007779984 1669384829871 4.5 GB
EGAF00007779985 1669383047491 4.4 GB
EGAF00007779986 1669381228155 5.0 GB
EGAF00007779987 1669383935832 5.1 GB
EGAF00007779988 1669380349913 11.7 GB
EGAF00007779989 1669385726263 11.4 GB
EGAF00007779990 1669379427372 854.5 MB
EGAF00007779991 1669379427372 844.4 MB
EGAF00007779992 1669383935832 2.6 GB
EGAF00007779993 1669379427372 2.6 GB
116 Files (576.8 GB)