Postmortem Single Nuclei and Bulk RNA-seq data of the Motor Cortex and Spinal Cord for Healthy, C9ALS and sALS Patients
This dataset contains both snRNA-seq and bulk RNA-seq data from 19 different patients, comprising of 9 healthy controls (4 Spinal Cord, 5 Motor Cortex) as well as 5 C9ALS patients and 5 sporadic ALS patients, each with paired data from the spinal cord and motor cortex. For the snRNA-seq data, fastq files containing the raw reads are provided, many of these samples were pooled for sequencing and subsequently require demultiplexing using SNPs using a tool such as freemuxlet. The paired bulk RNA-seq data (raw fastq files) can be used to acquire the ground truth per patient - a list of pooled samples can be found in map.txt. snRNA-seq data was produced using the 10X Genomics 3' v3 kit and bulk RNA-seq was produced using the Illumina TruSeq v2 kit.
- 64 samples
- DAC: EGAC00001002939
- Technology: Illumina NovaSeq 6000
VIB Policy for Data Access and Data Transfer
Applicability This policy applies to the access to and transfer of VIB research datasets that contain non-anonymous Personal Data which are subject to the provisions of the General Data Protection Regulation (EU) 2016/679. Access/transfer conditions - The access/transfer is subject to approval by the VIB Data Access Committee. - The proposed research purpose should not be incompatible with the primary research purpose for which the data were originally generated. - The Recipient shall have in place adequate safeguards for the protection of Personal Data. - Access is subject to a Data Transfer/Access Agreement which will be managed by VIB Innovation & Business. - The Data Transfer/Access will be limited to the Data that are necessary for the proposed research. Access/transfer procedure - Requests to access or obtain non-anonymous datasets should be submitted to the responsible corresponding author that has uploaded the dataset into the repository, and with a copy to dac@vib.be. - The request should contain the following information: - Name, affiliation (legal entity) and contact information of the requesting recipient party. - Reference to the specific dataset(s) for which access or transfer is requested. - Description of the research purpose for which the data will be used. - The VIB Data Access Committee takes decisions to approve access/transfer within 14 days upon receipt of the request. - Data access will be given / Data will be transferred after completion of the Data Transfer/Access Agreement.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001006711 | Other |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00007514206 | fastq.gz | 11.2 GB | ||
| EGAF00007514207 | fastq.gz | 26.5 GB | ||
| EGAF00007514208 | fastq.gz | 5.1 GB | ||
| EGAF00007514209 | fastq.gz | 11.6 GB | ||
| EGAF00007514210 | fastq.gz | 5.2 GB | ||
| EGAF00007514211 | fastq.gz | 11.9 GB | ||
| EGAF00007514212 | fastq.gz | 5.9 GB | ||
| EGAF00007514213 | fastq.gz | 13.7 GB | ||
| EGAF00007514214 | fastq.gz | 6.4 GB | ||
| EGAF00007514215 | fastq.gz | 14.7 GB | ||
| EGAF00007514216 | fastq.gz | 4.5 GB | ||
| EGAF00007514217 | fastq.gz | 10.8 GB | ||
| EGAF00007514218 | fastq.gz | 13.4 GB | ||
| EGAF00007514219 | fastq.gz | 31.7 GB | ||
| EGAF00007514220 | fastq.gz | 4.6 GB | ||
| EGAF00007514221 | fastq.gz | 11.1 GB | ||
| EGAF00007514222 | fastq.gz | 7.7 GB | ||
| EGAF00007514223 | fastq.gz | 17.9 GB | ||
| EGAF00007514224 | fastq.gz | 7.2 GB | ||
| EGAF00007514225 | fastq.gz | 16.7 GB | ||
| EGAF00007514226 | fastq.gz | 7.6 GB | ||
| EGAF00007514227 | fastq.gz | 17.5 GB | ||
| EGAF00007514228 | fastq.gz | 7.8 GB | ||
| EGAF00007514229 | fastq.gz | 18.3 GB | ||
| EGAF00007514230 | fastq.gz | 7.4 GB | ||
| EGAF00007514231 | fastq.gz | 17.3 GB | ||
| EGAF00007514232 | fastq.gz | 3.4 GB | ||
| EGAF00007514233 | fastq.gz | 7.7 GB | ||
| EGAF00007514234 | fastq.gz | 5.2 GB | ||
| EGAF00007514235 | fastq.gz | 11.9 GB | ||
| EGAF00007514236 | fastq.gz | 1.2 GB | ||
| EGAF00007514237 | fastq.gz | 1.1 GB | ||
| EGAF00007514238 | fastq.gz | 1.1 GB | ||
| EGAF00007514239 | fastq.gz | 1.2 GB | ||
| EGAF00007514240 | fastq.gz | 1.2 GB | ||
| EGAF00007514241 | fastq.gz | 1.2 GB | ||
| EGAF00007514242 | fastq.gz | 1.1 GB | ||
| EGAF00007514243 | fastq.gz | 893.2 MB | ||
| EGAF00007514244 | fastq.gz | 1.1 GB | ||
| EGAF00007514245 | fastq.gz | 1.0 GB | ||
| EGAF00007514246 | fastq.gz | 1.2 GB | ||
| EGAF00007514247 | fastq.gz | 914.6 MB | ||
| EGAF00007514248 | fastq.gz | 875.6 MB | ||
| EGAF00007514249 | fastq.gz | 931.8 MB | ||
| EGAF00007514250 | fastq.gz | 1.2 GB | ||
| EGAF00007514251 | fastq.gz | 1.1 GB | ||
| EGAF00007514252 | fastq.gz | 1.0 GB | ||
| EGAF00007514253 | fastq.gz | 935.3 MB | ||
| EGAF00007514254 | fastq.gz | 1.1 GB | ||
| EGAF00007514255 | fastq.gz | 3.8 GB | ||
| EGAF00007514256 | fastq.gz | 8.7 GB | ||
| EGAF00007514257 | fastq.gz | 3.2 GB | ||
| EGAF00007514258 | fastq.gz | 7.5 GB | ||
| EGAF00007514259 | fastq.gz | 3.5 GB | ||
| EGAF00007514260 | fastq.gz | 8.2 GB | ||
| EGAF00007514261 | fastq.gz | 3.0 GB | ||
| EGAF00007514262 | fastq.gz | 6.9 GB | ||
| EGAF00007514263 | fastq.gz | 1.9 GB | ||
| EGAF00007514264 | fastq.gz | 4.3 GB | ||
| EGAF00007514265 | fastq.gz | 4.2 GB | ||
| EGAF00007514266 | fastq.gz | 9.4 GB | ||
| EGAF00007514267 | txt | 2.2 kB | ||
| 62 Files (426.9 GB) | ||||