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Single nuclei RNA-Seq from 5 regions of the human fetal brain

Data generated through single nuclei RNA sequencing on 5 regions of the brain (frontal cortex, ganglionic eminence, hippocampus, thalamus and cerebellum) from 3 fetuses (two of 14 and one of 15 post-conception weeks, all female). Tissue was acquired from the MRC-Wellcome Trust Human Developmental Biology Resource (HDBR) with ethical approval. snRNA-seq libraries were prepared from ∼10,000 nuclei from each sample using Chromium Single Cell 3ʹ (v3) reagents (10X Genomics). Quality control of libraries was performed using the Agilent 5200 Fragment Analyzer before sequencing on an Illumina NovaSeq 6000 to a depth of at least 865 million (median = 1.01 billion) read pairs per library. Raw sequencing data were converted into FASTQ files. For a full description of data generation, please see Cameron et al, Biological Psychiatry 2022, https://doi.org/10.1016/j.biopsych.2022.06.033.

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Access to data is available through application to the Cardiff University DPMCN Functional Genomics Data Access Committee (email: BrayN3@Cardiff.ac.uk).

Access to data is available through application to the Cardiff University DPMCN Functional Genomics Data Access Committee (email: BrayN3@Cardiff.ac.uk). Data access will be granted to Principal Investigators with an institutional affiliation, and where the proposed research is consistent with the data use limitations of the dataset (based on original informed consent from the donors). 

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006895731 1661473821256 5.4 GB
EGAF00006895732 1661474721036 12.3 GB
EGAF00006895733 1661472921589 5.5 GB
EGAF00006895734 1661473821256 12.5 GB
EGAF00006895735 1661471121554 5.5 GB
EGAF00006895736 1661474721036 12.5 GB
EGAF00006895737 1661470221679 5.4 GB
EGAF00006895738 1661472021780 12.4 GB
EGAF00006895739 1661472021780 6.1 GB
EGAF00006895740 1661472021780 13.0 GB
EGAF00006895741 1661472021780 6.2 GB
EGAF00006895742 1661472921589 13.3 GB
EGAF00006895743 1661470221679 6.6 GB
EGAF00006895744 1661472921589 14.0 GB
EGAF00006895745 1661471121554 6.4 GB
EGAF00006895746 1661474721036 13.7 GB
EGAF00006895747 1661472921589 5.4 GB
EGAF00006895748 1661474721036 12.2 GB
EGAF00006895749 1661472021780 5.6 GB
EGAF00006895750 1661473821254 12.5 GB
EGAF00006895751 1661472921589 5.8 GB
EGAF00006895752 1661471121554 13.0 GB
EGAF00006895753 1661471121554 5.7 GB
EGAF00006895754 1661472021780 12.8 GB
EGAF00006895755 1661472021780 5.4 GB
EGAF00006895756 1661473821254 12.3 GB
EGAF00006895757 1661471121554 5.5 GB
EGAF00006895758 1661473821255 12.5 GB
EGAF00006895759 1661472021780 5.5 GB
EGAF00006895760 1661472021780 12.5 GB
EGAF00006895761 1661472021780 5.5 GB
EGAF00006895762 1661471121554 12.4 GB
EGAF00006895763 1661472021780 5.8 GB
EGAF00006895764 1661472921589 12.8 GB
EGAF00006895765 1661472021780 5.9 GB
EGAF00006895766 1661474721036 13.0 GB
EGAF00006895767 1661472921589 6.1 GB
EGAF00006895768 1661472921589 13.5 GB
EGAF00006895769 1661470221679 6.0 GB
EGAF00006895770 1661471121554 13.2 GB
EGAF00006895771 1661471121554 6.9 GB
EGAF00006895772 1661474721036 15.8 GB
EGAF00006895773 1661471121554 7.0 GB
EGAF00006895774 1661473821254 16.1 GB
EGAF00006895775 1661472921588 7.1 GB
EGAF00006895776 1661474721036 16.2 GB
EGAF00006895777 1661473821254 7.0 GB
EGAF00006895778 1661474721036 16.0 GB
EGAF00006895779 1661471121554 6.7 GB
EGAF00006895780 1661474721036 15.5 GB
EGAF00006895781 1661471121555 6.8 GB
EGAF00006895782 1661474721036 15.8 GB
EGAF00006895783 1661471121555 6.9 GB
EGAF00006895784 1661473821254 15.8 GB
EGAF00006895785 1661472921588 6.8 GB
EGAF00006895786 1661473821255 15.7 GB
EGAF00006895787 1661472921588 4.9 GB
EGAF00006895788 1661470221679 11.1 GB
EGAF00006895789 1661470221679 5.2 GB
EGAF00006895790 1661472021780 11.6 GB
EGAF00006895791 1661472021780 5.5 GB
EGAF00006895792 1661471121554 12.2 GB
EGAF00006895793 1661470221679 5.4 GB
EGAF00006895794 1661472921588 12.0 GB
EGAF00006895795 1661471121554 5.4 GB
EGAF00006895796 1661471121554 12.2 GB
EGAF00006895797 1661470221679 5.6 GB
EGAF00006895798 1661472921589 12.5 GB
EGAF00006895799 1661470221679 5.8 GB
EGAF00006895800 1661472021780 13.0 GB
EGAF00006895801 1661470221679 5.7 GB
EGAF00006895802 1661474721035 12.8 GB
EGAF00006895803 1661472021780 5.3 GB
EGAF00006895804 1661472921589 12.1 GB
EGAF00006895805 1661472921589 5.4 GB
EGAF00006895806 1661471121554 12.3 GB
EGAF00006895807 1661470221678 5.4 GB
EGAF00006895808 1661472921589 12.3 GB
EGAF00006895809 1661471121554 5.3 GB
EGAF00006895810 1661474721036 12.2 GB
EGAF00006895811 1661472021780 4.8 GB
EGAF00006895812 1661472921589 10.9 GB
EGAF00006895813 1661472021780 4.8 GB
EGAF00006895814 1661472021780 11.1 GB
EGAF00006895815 1661470221679 4.9 GB
EGAF00006895816 1661472021780 11.1 GB
EGAF00006895817 1661472921588 4.8 GB
EGAF00006895818 1661473821254 11.0 GB
EGAF00006895819 1661472921588 5.3 GB
EGAF00006895820 1661474721036 11.7 GB
EGAF00006895821 1661473821254 5.4 GB
EGAF00006895822 1661472921588 12.0 GB
EGAF00006895823 1661473821254 5.6 GB
EGAF00006895824 1661473821254 12.4 GB
EGAF00006895825 1661473821254 5.5 GB
EGAF00006895826 1661474721036 12.2 GB
EGAF00006895827 1661471121554 6.7 GB
EGAF00006895828 1661472921588 15.4 GB
EGAF00006895829 1661473821254 6.8 GB
EGAF00006895830 1661473821254 15.7 GB
EGAF00006895831 1661472021780 6.8 GB
EGAF00006895832 1661473821254 15.6 GB
EGAF00006895833 1661472921588 6.8 GB
EGAF00006895834 1661473821255 15.5 GB
EGAF00006895835 1661470221679 6.6 GB
EGAF00006895836 1661472021780 15.0 GB
EGAF00006895837 1661471121554 6.7 GB
EGAF00006895838 1661473821255 15.3 GB
EGAF00006895839 1661472021780 6.7 GB
EGAF00006895840 1661474721036 15.3 GB
EGAF00006895841 1661473821255 6.7 GB
EGAF00006895842 1661472921588 15.2 GB
EGAF00006895843 1661472921588 4.5 GB
EGAF00006895844 1661473821255 10.3 GB
EGAF00006895845 1661472921588 4.6 GB
EGAF00006895846 1661472921588 10.5 GB
EGAF00006895847 1661470221679 4.6 GB
EGAF00006895848 1661472921588 10.5 GB
EGAF00006895849 1661470221679 4.6 GB
EGAF00006895850 1661471121554 10.4 GB
EGAF00006895851 1661470221679 5.2 GB
EGAF00006895852 1661472921588 12.0 GB
EGAF00006895853 1661471121555 5.3 GB
EGAF00006895854 1661472021780 12.2 GB
EGAF00006895855 1661472021780 5.3 GB
EGAF00006895856 1661472921588 12.2 GB
EGAF00006895857 1661471121554 5.3 GB
EGAF00006895858 1661472921588 12.1 GB
EGAF00006895859 1661471121554 5.0 GB
EGAF00006895860 1661471121554 11.4 GB
EGAF00006895861 1661472021780 5.1 GB
EGAF00006895862 1661472921588 11.6 GB
EGAF00006895863 1661472021780 5.1 GB
EGAF00006895864 1661474721036 11.6 GB
EGAF00006895865 1661472921588 5.0 GB
EGAF00006895866 1661472921588 11.5 GB
136 Files (1.3 TB)