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Epigenomic analysis of human dopaminergic neuron differentiation reveals LBX1, NHLH1 and NR2F1/2 as necessary for lineage specification

Sample information: The 56 samples produced in this project come from the human iPSC line GM17602 (Coriell) where a tyrosine hydroxylase-T2A-mCherry reporter was inserted. A combination of epigenetic analysis (ATAC/ChIP) along transcriptomics.

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The access to the data will be granted by the Data Access Committee (DAC). The DACs will review and approve or disapprove all requests from the research community for data access. Decisions to grant access are made based on whether the request conforms to the specifications within this data access policy. If the DAC decides to grant access, a Data Access Agreement must be signed between the data owner and the user institution.

Data Access Policy 1. The access to the data will be granted by the Data Access Committee (DAC). The DACs will review and approve or disapprove all requests from the research community for data access. Decisions to grant access are made based on whether the request conforms to the specifications within this data access policy. If the DAC decides to grant access, a Data Access Agreement must be signed between the data owner and the user institution. 2. Applications are welcome for studies in all research areas 3. The User Institution agrees to only use these Data for the purpose of the Project and only for Research Purposes. 4. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. 5. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 6. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 7. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 8. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 9. The User Institution agrees to follow the Publication Policy which includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 10. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of of these Data, or conclusion drawn directly from these Data 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other
Other
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006863937 1661170522264 1.5 GB
EGAF00006863938 1661169624336 1.6 GB
EGAF00006863939 1661169624336 1.5 GB
EGAF00006863940 1661169624336 1.5 GB
EGAF00006863941 1661169624336 1.5 GB
EGAF00006863942 1661169624336 1.6 GB
EGAF00006863943 1661169624336 1.6 GB
EGAF00006863944 1661169624336 1.6 GB
EGAF00006863945 1661170522264 1.7 GB
EGAF00006863946 1661170522264 1.8 GB
EGAF00006863947 1661169624336 1.6 GB
EGAF00006863948 1661170522264 1.6 GB
EGAF00006863949 1661169624336 1.6 GB
EGAF00006863950 1661169624336 1.7 GB
EGAF00006863951 1661169624336 1.6 GB
EGAF00006863952 1661170522264 1.6 GB
EGAF00006863953 1661169624336 1.6 GB
EGAF00006863954 1661170522264 1.6 GB
EGAF00006863955 1661170522264 1.6 GB
EGAF00006863956 1661170522264 1.7 GB
EGAF00006863957 1661170522264 1.4 GB
EGAF00006863958 1661169624336 1.5 GB
EGAF00006863959 1661170522264 1.5 GB
EGAF00006863960 1661169624336 1.5 GB
EGAF00006863961 1661170522264 1.6 GB
EGAF00006863962 1661169624336 1.6 GB
EGAF00006863963 1661170522264 1.7 GB
EGAF00006863964 1661169624336 1.7 GB
EGAF00006863965 1661170522264 1.7 GB
EGAF00006863966 1661169624336 1.8 GB
EGAF00006863967 1661170522264 1.6 GB
EGAF00006863968 1661169624336 1.6 GB
EGAF00006863969 1661169624336 1.7 GB
EGAF00006863970 1661169624336 1.7 GB
EGAF00006863971 1661169624336 1.7 GB
EGAF00006863972 1661170522264 1.8 GB
EGAF00006863973 1661169624336 1.5 GB
EGAF00006863974 1661169624336 1.5 GB
EGAF00006863975 1661170522264 1.6 GB
EGAF00006863976 1661170522264 1.6 GB
EGAF00006863977 1661170522264 1.6 GB
EGAF00006863978 1661170522264 1.6 GB
EGAF00006863979 1661168722949 1.9 GB
EGAF00006863980 1661168722949 1.9 GB
EGAF00006864005 1661167822217 1.4 GB
EGAF00006864006 1661167822217 3.1 GB
EGAF00006864007 1661167822217 3.2 GB
EGAF00006864008 1661167822217 1.1 GB
EGAF00006864009 1661171423700 3.3 GB
EGAF00006864010 1661172321728 3.3 GB
EGAF00006864011 1661169624336 1.7 GB
EGAF00006864012 1661171423700 3.6 GB
EGAF00006864013 1661170522264 3.7 GB
EGAF00006864014 1661168722949 1.0 GB
EGAF00006864015 1661167822217 388.2 MB
EGAF00006864016 1661167822217 899.3 MB
EGAF00006864017 1661167822217 232.2 MB
EGAF00006864018 1661167822217 764.6 MB
EGAF00006864019 1661167822217 200.3 MB
EGAF00006864020 1661167822217 1.0 GB
EGAF00006864021 1661167822217 259.2 MB
EGAF00006864022 1661167822217 1.0 GB
EGAF00006864023 1661167822217 273.6 MB
EGAF00006864024 1661168722949 706.8 MB
EGAF00006864025 1661168722949 194.3 MB
EGAF00006864026 1661168722949 1.3 GB
EGAF00006864027 1661167822217 427.0 MB
EGAF00006864028 1661167822217 873.0 MB
EGAF00006864029 1661167822217 225.5 MB
EGAF00006864030 1661170522264 3.5 GB
EGAF00006864031 1661170522264 3.6 GB
EGAF00006864032 1661169624336 1.7 GB
EGAF00006864033 1661171423700 3.5 GB
EGAF00006864034 1661169624336 3.6 GB
EGAF00006864035 1661171423700 1.8 GB
EGAF00006864036 1661169624336 4.1 GB
EGAF00006864037 1661171423700 4.1 GB
EGAF00006864038 1661169624336 4.2 GB
EGAF00006864039 1661173221410 4.3 GB
EGAF00006864040 1661169624336 1.6 GB
EGAF00006864041 1661170522264 4.8 GB
EGAF00006864042 1661173221410 4.9 GB
EGAF00006864043 1661169624336 1.6 GB
EGAF00006864044 1661168722949 3.9 GB
EGAF00006864045 1661169624336 4.0 GB
EGAF00006864046 1661168722949 1.0 GB
EGAF00006864047 1661168722949 266.7 MB
EGAF00006864048 1661169624336 859.4 MB
EGAF00006864049 1661168722949 222.0 MB
EGAF00006864050 1661167822217 1.2 GB
EGAF00006864051 1661168722949 314.4 MB
EGAF00006864052 1661169624336 865.5 MB
EGAF00006864053 1661169624336 223.3 MB
EGAF00006864054 1661170522264 2.0 GB
EGAF00006864055 1661171423700 1.5 GB
EGAF00006864056 1661170522264 1.4 GB
EGAF00006864057 1661169624336 1.5 GB
EGAF00006864058 1661168722949 1.7 GB
EGAF00006864059 1661169624336 1.6 GB
EGAF00006864060 1661168722949 968.7 MB
EGAF00006864061 1661170522264 2.0 GB
EGAF00006864062 1661172321728 1.8 GB
EGAF00006864063 1661167822217 1.3 GB
EGAF00006864064 1661169624336 1.2 GB
EGAF00006864065 1661167822217 325.1 MB
EGAF00006864066 1661170522264 1.3 GB
EGAF00006864067 1661170522264 1.8 GB
EGAF00006864068 1661169624336 1.5 GB
EGAF00006864069 1661169624336 1.5 GB
109 Files (188.9 GB)