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Epigenomic analysis of human dopaminergic neuron differentiation reveals LBX1, NHLH1 and NR2F1/2 as necessary for lineage specification

Sample information: The 56 samples produced in this project come from the human iPSC line GM17602 (Coriell) where a tyrosine hydroxylase-T2A-mCherry reporter was inserted. A combination of epigenetic analysis (ATAC/ChIP) along transcriptomics.

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The access to the data will be granted by the Data Access Committee (DAC). The DACs will review and approve or disapprove all requests from the research community for data access. Decisions to grant access are made based on whether the request conforms to the specifications within this data access policy. If the DAC decides to grant access, a Data Access Agreement must be signed between the data owner and the user institution.

Data Access Policy 1. The access to the data will be granted by the Data Access Committee (DAC). The DACs will review and approve or disapprove all requests from the research community for data access. Decisions to grant access are made based on whether the request conforms to the specifications within this data access policy. If the DAC decides to grant access, a Data Access Agreement must be signed between the data owner and the user institution. 2. Applications are welcome for studies in all research areas 3. The User Institution agrees to only use these Data for the purpose of the Project and only for Research Purposes. 4. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. 5. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 6. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 7. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 8. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 9. The User Institution agrees to follow the Publication Policy which includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 10. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of of these Data, or conclusion drawn directly from these Data 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006520 Other
EGAS00001006521 Other
EGAS00001006522 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006863937 fastq.gz 1.5 GB
EGAF00006863938 fastq.gz 1.6 GB
EGAF00006863939 fastq.gz 1.5 GB
EGAF00006863940 fastq.gz 1.5 GB
EGAF00006863941 fastq.gz 1.5 GB
EGAF00006863942 fastq.gz 1.6 GB
EGAF00006863943 fastq.gz 1.6 GB
EGAF00006863944 fastq.gz 1.6 GB
EGAF00006863945 fastq.gz 1.7 GB
EGAF00006863946 fastq.gz 1.8 GB
EGAF00006863947 fastq.gz 1.6 GB
EGAF00006863948 fastq.gz 1.6 GB
EGAF00006863949 fastq.gz 1.6 GB
EGAF00006863950 fastq.gz 1.7 GB
EGAF00006863951 fastq.gz 1.6 GB
EGAF00006863952 fastq.gz 1.6 GB
EGAF00006863953 fastq.gz 1.6 GB
EGAF00006863954 fastq.gz 1.6 GB
EGAF00006863955 fastq.gz 1.6 GB
EGAF00006863956 fastq.gz 1.7 GB
EGAF00006863957 fastq.gz 1.4 GB
EGAF00006863958 fastq.gz 1.5 GB
EGAF00006863959 fastq.gz 1.5 GB
EGAF00006863960 fastq.gz 1.5 GB
EGAF00006863961 fastq.gz 1.6 GB
EGAF00006863962 fastq.gz 1.6 GB
EGAF00006863963 fastq.gz 1.7 GB
EGAF00006863964 fastq.gz 1.7 GB
EGAF00006863965 fastq.gz 1.7 GB
EGAF00006863966 fastq.gz 1.8 GB
EGAF00006863967 fastq.gz 1.6 GB
EGAF00006863968 fastq.gz 1.6 GB
EGAF00006863969 fastq.gz 1.7 GB
EGAF00006863970 fastq.gz 1.7 GB
EGAF00006863971 fastq.gz 1.7 GB
EGAF00006863972 fastq.gz 1.8 GB
EGAF00006863973 fastq.gz 1.5 GB
EGAF00006863974 fastq.gz 1.5 GB
EGAF00006863975 fastq.gz 1.6 GB
EGAF00006863976 fastq.gz 1.6 GB
EGAF00006863977 fastq.gz 1.6 GB
EGAF00006863978 fastq.gz 1.6 GB
EGAF00006863979 fastq.gz 1.9 GB
EGAF00006863980 fastq.gz 1.9 GB
EGAF00006864005 fastq.gz 1.4 GB
EGAF00006864006 fastq.gz 3.1 GB
EGAF00006864007 fastq.gz 3.2 GB
EGAF00006864008 fastq.gz 1.1 GB
EGAF00006864009 fastq.gz 3.3 GB
EGAF00006864010 fastq.gz 3.3 GB
EGAF00006864011 fastq.gz 1.7 GB
EGAF00006864012 fastq.gz 3.6 GB
EGAF00006864013 fastq.gz 3.7 GB
EGAF00006864014 fastq.gz 1.0 GB
EGAF00006864015 fastq.gz 388.2 MB
EGAF00006864016 fastq.gz 899.3 MB
EGAF00006864017 fastq.gz 232.2 MB
EGAF00006864018 fastq.gz 764.6 MB
EGAF00006864019 fastq.gz 200.3 MB
EGAF00006864020 fastq.gz 1.0 GB
EGAF00006864021 fastq.gz 259.2 MB
EGAF00006864022 fastq.gz 1.0 GB
EGAF00006864023 fastq.gz 273.6 MB
EGAF00006864024 fastq.gz 706.8 MB
EGAF00006864025 fastq.gz 194.3 MB
EGAF00006864026 fastq.gz 1.3 GB
EGAF00006864027 fastq.gz 427.0 MB
EGAF00006864028 fastq.gz 873.0 MB
EGAF00006864029 fastq.gz 225.5 MB
EGAF00006864030 fastq.gz 3.5 GB
EGAF00006864031 fastq.gz 3.6 GB
EGAF00006864032 fastq.gz 1.7 GB
EGAF00006864033 fastq.gz 3.5 GB
EGAF00006864034 fastq.gz 3.6 GB
EGAF00006864035 fastq.gz 1.8 GB
EGAF00006864036 fastq.gz 4.1 GB
EGAF00006864037 fastq.gz 4.1 GB
EGAF00006864038 fastq.gz 4.2 GB
EGAF00006864039 fastq.gz 4.3 GB
EGAF00006864040 fastq.gz 1.6 GB
EGAF00006864041 fastq.gz 4.8 GB
EGAF00006864042 fastq.gz 4.9 GB
EGAF00006864043 fastq.gz 1.6 GB
EGAF00006864044 fastq.gz 3.9 GB
EGAF00006864045 fastq.gz 4.0 GB
EGAF00006864046 fastq.gz 1.0 GB
EGAF00006864047 fastq.gz 266.7 MB
EGAF00006864048 fastq.gz 859.4 MB
EGAF00006864049 fastq.gz 222.0 MB
EGAF00006864050 fastq.gz 1.2 GB
EGAF00006864051 fastq.gz 314.4 MB
EGAF00006864052 fastq.gz 865.5 MB
EGAF00006864053 fastq.gz 223.3 MB
EGAF00006864054 fastq.gz 2.0 GB
EGAF00006864055 fastq.gz 1.5 GB
EGAF00006864056 fastq.gz 1.4 GB
EGAF00006864057 fastq.gz 1.5 GB
EGAF00006864058 fastq.gz 1.7 GB
EGAF00006864059 fastq.gz 1.6 GB
EGAF00006864060 fastq.gz 968.7 MB
EGAF00006864061 fastq.gz 2.0 GB
EGAF00006864062 fastq.gz 1.8 GB
EGAF00006864063 fastq.gz 1.3 GB
EGAF00006864064 fastq.gz 1.2 GB
EGAF00006864065 fastq.gz 325.1 MB
EGAF00006864066 fastq.gz 1.3 GB
EGAF00006864067 fastq.gz 1.8 GB
EGAF00006864068 fastq.gz 1.5 GB
EGAF00006864069 fastq.gz 1.5 GB
109 Files (188.9 GB)