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Bone marrow microenvironment of 6 newly diagnosed myeloma patients using 10X Genomics scRNA- and TCR-sequencing

10X Genomics scRNA- and TCR-sequencing (Chromium Next GEM Single Cell 5’ Reagent Kit v1.1) was performed on the plasma cell depleted mononuclear fraction of bone marrow aspirates from 6 patients with newly diagnosed multiple myeloma. Generated gene expression libraries were paired-end sequenced on the NovaSeq 6000 S2. Generated V(D)J libraries were paired-end sequenced on the NextSeq 550.

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Data Transfer Agreement for the German Cancer Research Center

To request access to the dataset please start a Data Access Request via the EGA DAC Portal. You will receive a HIPO DACO Info Form by email to collect information about the request, which has to be filled completely and signed by your PI. Your request will be evaluated by the responsible Data Access Committee (DAC) and our Data protection department (and innovation management if required). As soon as a positive decision is made, you will be provided with a data transfer agreement (DTA). After the DTA has been fully signed, access to the requested data is granted. To ensure that the process can be completed as quickly as possible, please note the following points: 1. The request in the EGA portal must be made by the responsible PI. 2. The information in the EGA portal must match the information on the HIPO DACO Info Form. In particular, the email address and the requested data sets must match. It is also important that all requested data sets are also listed on the HIPO DACO Info Form. For-profit companies are charged a fee per request.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006090 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006134000 fastq.gz 94.7 MB
EGAF00006134001 fastq.gz 89.1 MB
EGAF00006134002 fastq.gz 89.9 MB
EGAF00006134003 fastq.gz 82.7 MB
EGAF00006134004 fastq.gz 80.8 MB
EGAF00006134005 fastq.gz 75.7 MB
EGAF00006134012 fastq.gz 134.4 MB
EGAF00006134013 fastq.gz 130.1 MB
EGAF00006134026 fastq.gz 82.5 MB
EGAF00006134027 fastq.gz 79.5 MB
EGAF00006134034 fastq.gz 135.0 MB
EGAF00006134035 fastq.gz 121.7 MB
EGAF00006134038 fastq.gz 103.8 MB
EGAF00006134039 fastq.gz 97.1 MB
EGAF00006134040 fastq.gz 103.7 MB
EGAF00006134041 fastq.gz 96.9 MB
EGAF00006134042 fastq.gz 129.4 MB
EGAF00006134043 fastq.gz 120.4 MB
EGAF00006134052 fastq.gz 107.6 MB
EGAF00006134053 fastq.gz 100.2 MB
EGAF00006134056 fastq.gz 90.5 MB
EGAF00006134057 fastq.gz 81.5 MB
EGAF00006134062 fastq.gz 104.6 MB
EGAF00006134063 fastq.gz 96.6 MB
EGAF00006134064 fastq.gz 100.5 MB
EGAF00006134065 fastq.gz 90.5 MB
EGAF00006134072 fastq.gz 73.6 MB
EGAF00006134073 fastq.gz 68.9 MB
EGAF00006134078 fastq.gz 108.3 MB
EGAF00006134079 fastq.gz 103.7 MB
EGAF00006134082 fastq.gz 101.6 MB
EGAF00006134083 fastq.gz 97.1 MB
EGAF00006134092 fastq.gz 99.5 MB
EGAF00006134093 fastq.gz 91.2 MB
EGAF00006134094 fastq.gz 80.2 MB
EGAF00006134095 fastq.gz 73.9 MB
EGAF00006134096 fastq.gz 83.9 MB
EGAF00006134097 fastq.gz 76.5 MB
EGAF00006134144 fastq.gz 102.2 MB
EGAF00006134145 fastq.gz 95.5 MB
EGAF00006134146 fastq.gz 86.6 MB
EGAF00006134147 fastq.gz 80.6 MB
EGAF00006134148 fastq.gz 83.0 MB
EGAF00006134149 fastq.gz 76.3 MB
EGAF00006134164 fastq.gz 89.8 MB
EGAF00006134165 fastq.gz 81.2 MB
EGAF00006134172 fastq.gz 76.3 MB
EGAF00006134173 fastq.gz 71.6 MB
EGAF00006134320 fastq.gz 575.1 MB
EGAF00006134321 fastq.gz 1.5 GB
EGAF00006134322 fastq.gz 526.0 MB
EGAF00006134323 fastq.gz 1.3 GB
EGAF00006134326 fastq.gz 531.2 MB
EGAF00006134327 fastq.gz 1.3 GB
EGAF00006134350 fastq.gz 582.2 MB
EGAF00006134351 fastq.gz 1.5 GB
EGAF00006134362 fastq.gz 629.6 MB
EGAF00006134363 fastq.gz 1.6 GB
EGAF00006134364 fastq.gz 429.5 MB
EGAF00006134365 fastq.gz 1.1 GB
EGAF00006134406 fastq.gz 618.9 MB
EGAF00006134407 fastq.gz 1.6 GB
EGAF00006134408 fastq.gz 410.5 MB
EGAF00006134409 fastq.gz 1.0 GB
EGAF00006134418 fastq.gz 444.4 MB
EGAF00006134419 fastq.gz 1.1 GB
EGAF00006134440 fastq.gz 388.1 MB
EGAF00006134441 fastq.gz 960.9 MB
EGAF00006134442 fastq.gz 830.6 MB
EGAF00006134443 fastq.gz 2.1 GB
EGAF00006134448 fastq.gz 661.5 MB
EGAF00006134449 fastq.gz 1.7 GB
EGAF00006134462 fastq.gz 577.9 MB
EGAF00006134463 fastq.gz 1.5 GB
EGAF00006134466 fastq.gz 767.7 MB
EGAF00006134467 fastq.gz 2.0 GB
EGAF00006134492 fastq.gz 605.6 MB
EGAF00006134493 fastq.gz 1.5 GB
EGAF00006134496 fastq.gz 600.8 MB
EGAF00006134497 fastq.gz 1.5 GB
EGAF00006134502 fastq.gz 391.1 MB
EGAF00006134503 fastq.gz 966.7 MB
EGAF00006134508 fastq.gz 666.9 MB
EGAF00006134509 fastq.gz 1.7 GB
EGAF00006134510 fastq.gz 539.8 MB
EGAF00006134511 fastq.gz 1.4 GB
EGAF00006134518 fastq.gz 524.0 MB
EGAF00006134519 fastq.gz 1.3 GB
EGAF00006134520 fastq.gz 424.9 MB
EGAF00006134521 fastq.gz 1.1 GB
EGAF00006134532 fastq.gz 835.3 MB
EGAF00006134533 fastq.gz 2.1 GB
EGAF00006134550 fastq.gz 802.1 MB
EGAF00006134551 fastq.gz 2.0 GB
EGAF00006134552 fastq.gz 643.1 MB
EGAF00006134553 fastq.gz 1.6 GB
EGAF00006134592 fastq.gz 610.0 MB
EGAF00006134593 fastq.gz 1.6 GB
EGAF00006134594 fastq.gz 543.7 MB
EGAF00006134595 fastq.gz 1.4 GB
EGAF00006134650 fastq.gz 578.4 MB
EGAF00006134651 fastq.gz 1.5 GB
EGAF00006134652 fastq.gz 472.0 MB
EGAF00006134653 fastq.gz 1.2 GB
EGAF00006134676 fastq.gz 464.1 MB
EGAF00006134677 fastq.gz 1.2 GB
EGAF00006134680 fastq.gz 762.1 MB
EGAF00006134681 fastq.gz 1.9 GB
EGAF00006134732 fastq.gz 650.1 MB
EGAF00006134733 fastq.gz 1.7 GB
EGAF00006134736 fastq.gz 810.4 MB
EGAF00006134737 fastq.gz 2.1 GB
EGAF00006134740 fastq.gz 528.1 MB
EGAF00006134741 fastq.gz 1.3 GB
EGAF00006134750 fastq.gz 527.1 MB
EGAF00006134751 fastq.gz 1.3 GB
EGAF00006134752 fastq.gz 521.4 MB
EGAF00006134753 fastq.gz 1.3 GB
EGAF00006134758 fastq.gz 466.2 MB
EGAF00006134759 fastq.gz 1.1 GB
EGAF00006134760 fastq.gz 467.7 MB
EGAF00006134761 fastq.gz 1.2 GB
EGAF00006134762 fastq.gz 456.4 MB
EGAF00006134763 fastq.gz 1.1 GB
EGAF00006134768 fastq.gz 440.9 MB
EGAF00006134769 fastq.gz 1.1 GB
EGAF00006134830 fastq.gz 612.4 MB
EGAF00006134831 fastq.gz 1.5 GB
EGAF00006134832 fastq.gz 406.3 MB
EGAF00006134833 fastq.gz 1.0 GB
EGAF00006134856 fastq.gz 646.2 MB
EGAF00006134857 fastq.gz 1.6 GB
EGAF00006134862 fastq.gz 606.3 MB
EGAF00006134863 fastq.gz 1.5 GB
EGAF00006134864 fastq.gz 636.0 MB
EGAF00006134865 fastq.gz 1.6 GB
EGAF00006134866 fastq.gz 453.2 MB
EGAF00006134867 fastq.gz 1.1 GB
EGAF00006134868 fastq.gz 462.5 MB
EGAF00006134869 fastq.gz 1.1 GB
EGAF00006134880 fastq.gz 468.1 MB
EGAF00006134881 fastq.gz 1.2 GB
EGAF00006134884 fastq.gz 640.0 MB
EGAF00006134885 fastq.gz 1.6 GB
144 Files (100.4 GB)