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Bone marrow microenvironment of 6 newly diagnosed myeloma patients using 10X Genomics scRNA- and TCR-sequencing

10X Genomics scRNA- and TCR-sequencing (Chromium Next GEM Single Cell 5’ Reagent Kit v1.1) was performed on the plasma cell depleted mononuclear fraction of bone marrow aspirates from 6 patients with newly diagnosed multiple myeloma. Generated gene expression libraries were paired-end sequenced on the NovaSeq 6000 S2. Generated V(D)J libraries were paired-end sequenced on the NextSeq 550.

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Data Transfer Agreement for the German Cancer Research Center

To request access to the dataset please start a Data Access Request via the EGA DAC Portal. You will receive a HIPO DACO Info Form by email to collect information about the request, which has to be filled completely and signed by your PI. Your request will be evaluated by the responsible Data Access Committee (DAC) and our Data protection department (and innovation management if required). As soon as a positive decision is made, you will be provided with a data transfer agreement (DTA). After the DTA has been fully signed, access to the requested data is granted. To ensure that the process can be completed as quickly as possible, please note the following points: 1. The request in the EGA portal must be made by the responsible PI. 2. The information in the EGA portal must match the information on the HIPO DACO Info Form. In particular, the email address and the requested data sets must match. It is also important that all requested data sets are also listed on the HIPO DACO Info Form. For-profit companies are charged a fee per request.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006134000 1648044604678 94.7 MB
EGAF00006134001 1648044507302 89.1 MB
EGAF00006134002 1648044507302 89.9 MB
EGAF00006134003 1648044507302 82.7 MB
EGAF00006134004 1648044604678 80.8 MB
EGAF00006134005 1648044507302 75.7 MB
EGAF00006134012 1648044557893 134.4 MB
EGAF00006134013 1648044507302 130.1 MB
EGAF00006134026 1648044507302 82.5 MB
EGAF00006134027 1648044557893 79.5 MB
EGAF00006134034 1648044557893 135.0 MB
EGAF00006134035 1648044557893 121.7 MB
EGAF00006134038 1648044604678 103.8 MB
EGAF00006134039 1648044557893 97.1 MB
EGAF00006134040 1648044557893 103.7 MB
EGAF00006134041 1648044604678 96.9 MB
EGAF00006134042 1648044604678 129.4 MB
EGAF00006134043 1648044604678 120.4 MB
EGAF00006134052 1648044557893 107.6 MB
EGAF00006134053 1648044507302 100.2 MB
EGAF00006134056 1648044557893 90.5 MB
EGAF00006134057 1648044557893 81.5 MB
EGAF00006134062 1648044557893 104.6 MB
EGAF00006134063 1648044604678 96.6 MB
EGAF00006134064 1648044557893 100.5 MB
EGAF00006134065 1648044557893 90.5 MB
EGAF00006134072 1648044557893 73.6 MB
EGAF00006134073 1648044557893 68.9 MB
EGAF00006134078 1648044604678 108.3 MB
EGAF00006134079 1648044557893 103.7 MB
EGAF00006134082 1648044604678 101.6 MB
EGAF00006134083 1648044557893 97.1 MB
EGAF00006134092 1648044507299 99.5 MB
EGAF00006134093 1648044507299 91.2 MB
EGAF00006134094 1648044507299 80.2 MB
EGAF00006134095 1648044557893 73.9 MB
EGAF00006134096 1648044507302 83.9 MB
EGAF00006134097 1648044507302 76.5 MB
EGAF00006134144 1648044557893 102.2 MB
EGAF00006134145 1648044557893 95.5 MB
EGAF00006134146 1648044557893 86.6 MB
EGAF00006134147 1648044604678 80.6 MB
EGAF00006134148 1648044557893 83.0 MB
EGAF00006134149 1648044557893 76.3 MB
EGAF00006134164 1648044557893 89.8 MB
EGAF00006134165 1648044507299 81.2 MB
EGAF00006134172 1648044557893 76.3 MB
EGAF00006134173 1648044507299 71.6 MB
EGAF00006134320 1648127640435 575.1 MB
EGAF00006134321 1648128600986 1.5 GB
EGAF00006134322 1648127640435 526.0 MB
EGAF00006134323 1648129021835 1.3 GB
EGAF00006134326 1648127820809 531.2 MB
EGAF00006134327 1648128061331 1.3 GB
EGAF00006134350 1648126986270 582.2 MB
EGAF00006134351 1648127460166 1.5 GB
EGAF00006134362 1648126686483 629.6 MB
EGAF00006134363 1648126562016 1.6 GB
EGAF00006134364 1648126201203 429.5 MB
EGAF00006134365 1648127115775 1.1 GB
EGAF00006134406 1648125664069 618.9 MB
EGAF00006134407 1648125905727 1.6 GB
EGAF00006134408 1648125962499 410.5 MB
EGAF00006134409 1648125330469 1.0 GB
EGAF00006134418 1648125195750 444.4 MB
EGAF00006134419 1648125242630 1.1 GB
EGAF00006134440 1648125005154 388.1 MB
EGAF00006134441 1648125127224 960.9 MB
EGAF00006134442 1648125242630 830.6 MB
EGAF00006134443 1648125363695 2.1 GB
EGAF00006134448 1648124944721 661.5 MB
EGAF00006134449 1648125664069 1.7 GB
EGAF00006134462 1648124944721 577.9 MB
EGAF00006134463 1648125561454 1.5 GB
EGAF00006134466 1648125195749 767.7 MB
EGAF00006134467 1648125195750 2.0 GB
EGAF00006134492 1648124467349 605.6 MB
EGAF00006134493 1648125005154 1.5 GB
EGAF00006134496 1648124467349 600.8 MB
EGAF00006134497 1648124591301 1.5 GB
EGAF00006134502 1648124206036 391.1 MB
EGAF00006134503 1648124312942 966.7 MB
EGAF00006134508 1648124206036 666.9 MB
EGAF00006134509 1648124405498 1.7 GB
EGAF00006134510 1648124110864 539.8 MB
EGAF00006134511 1648124206036 1.4 GB
EGAF00006134518 1648124223809 524.0 MB
EGAF00006134519 1648124405498 1.3 GB
EGAF00006134520 1648124110864 424.9 MB
EGAF00006134521 1648124467349 1.1 GB
EGAF00006134532 1648124824890 835.3 MB
EGAF00006134533 1648124467349 2.1 GB
EGAF00006134550 1648124591301 802.1 MB
EGAF00006134551 1648124944721 2.0 GB
EGAF00006134552 1648124405498 643.1 MB
EGAF00006134553 1648124529521 1.6 GB
EGAF00006134592 1648125794581 610.0 MB
EGAF00006134593 1648126396014 1.6 GB
EGAF00006134594 1648126085052 543.7 MB
EGAF00006134595 1648126262993 1.4 GB
EGAF00006134650 1648123624242 578.4 MB
EGAF00006134651 1648123865016 1.5 GB
EGAF00006134652 1648123685946 472.0 MB
EGAF00006134653 1648126327345 1.2 GB
EGAF00006134676 1648125195749 464.1 MB
EGAF00006134677 1648123685946 1.2 GB
EGAF00006134680 1648123562230 762.1 MB
EGAF00006134681 1648123685946 1.9 GB
EGAF00006134732 1648124110864 650.1 MB
EGAF00006134733 1648124206036 1.7 GB
EGAF00006134736 1648123926163 810.4 MB
EGAF00006134737 1648127041330 2.1 GB
EGAF00006134740 1648123865016 528.1 MB
EGAF00006134741 1648124312942 1.3 GB
EGAF00006134750 1648124591301 527.1 MB
EGAF00006134751 1648124110864 1.3 GB
EGAF00006134752 1648124206036 521.4 MB
EGAF00006134753 1648124110864 1.3 GB
EGAF00006134758 1648123926163 466.2 MB
EGAF00006134759 1648125794581 1.1 GB
EGAF00006134760 1648124045248 467.7 MB
EGAF00006134761 1648124206036 1.2 GB
EGAF00006134762 1648123746113 456.4 MB
EGAF00006134763 1648124206036 1.1 GB
EGAF00006134768 1648124110864 440.9 MB
EGAF00006134769 1648125425621 1.1 GB
EGAF00006134830 1648124794004 612.4 MB
EGAF00006134831 1648125794581 1.5 GB
EGAF00006134832 1648123624242 406.3 MB
EGAF00006134833 1648124003543 1.0 GB
EGAF00006134856 1648124003543 646.2 MB
EGAF00006134857 1648125664069 1.6 GB
EGAF00006134862 1648123685946 606.3 MB
EGAF00006134863 1648124643302 1.5 GB
EGAF00006134864 1648123865016 636.0 MB
EGAF00006134865 1648125330469 1.6 GB
EGAF00006134866 1648125330469 453.2 MB
EGAF00006134867 1648123926163 1.1 GB
EGAF00006134868 1648124405498 462.5 MB
EGAF00006134869 1648123865016 1.1 GB
EGAF00006134880 1648123808330 468.1 MB
EGAF00006134881 1648125425621 1.2 GB
EGAF00006134884 1648124591301 640.0 MB
EGAF00006134885 1648125841917 1.6 GB
144 Files (100.4 GB)