ESR1 mutations in tamoxifen-associated endometrial cancer versus spontaneous arisen endometrial tumors
An increased incidence of endometrial cancer has been described for patients that have received tamoxifen to treat breast cancer. Using samples from endometrial tumors, isolated from surgivcal specimens of patients who previously received tamoxifen treatment for breast cancer, we aimed to identify whether there are specific somatic mutations enriched in this population, relative to endometrial tumors from the general population. For this, WES was performed on matched endometrial tumors and healthy tissue (n=21).
- 42 samples
- DAC: EGAC00001002782
- Technology: Illumina HiSeq 2000
NKI Wilbert Zwart Group Data Access Committee
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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001006453 | Other |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00006566577 | bam | 20.5 GB | ||
| EGAF00006566578 | bam | 55.6 GB | ||
| EGAF00006566579 | bam | 8.0 GB | ||
| EGAF00006566580 | bam | 12.3 GB | ||
| EGAF00006566581 | bam | 10.6 GB | ||
| EGAF00006566582 | bam | 20.8 GB | ||
| EGAF00006566583 | bam | 12.0 GB | ||
| EGAF00006566584 | bam | 15.9 GB | ||
| EGAF00006566585 | bam | 13.4 GB | ||
| EGAF00006566586 | bam | 27.3 GB | ||
| EGAF00006566587 | bam | 10.1 GB | ||
| EGAF00006566588 | bam | 19.9 GB | ||
| EGAF00006566589 | bam | 8.6 GB | ||
| EGAF00006566590 | bam | 61.6 GB | ||
| EGAF00006566591 | bam | 7.7 GB | ||
| EGAF00006566592 | bam | 11.1 GB | ||
| EGAF00006566593 | bam | 11.0 GB | ||
| EGAF00006566594 | bam | 11.3 GB | ||
| EGAF00006566595 | bam | 3.7 GB | ||
| EGAF00006566596 | bam | 4.1 GB | ||
| EGAF00006566597 | bam | 24.2 GB | ||
| EGAF00006566598 | bam | 36.7 GB | ||
| EGAF00006566599 | bam | 2.2 GB | ||
| EGAF00006566600 | bam | 5.8 GB | ||
| EGAF00006566601 | bam | 16.7 GB | ||
| EGAF00006566602 | bam | 26.6 GB | ||
| EGAF00006566603 | bam | 10.2 GB | ||
| EGAF00006566604 | bam | 16.9 GB | ||
| EGAF00006566605 | bam | 6.0 GB | ||
| EGAF00006566606 | bam | 19.0 GB | ||
| EGAF00006566607 | bam | 24.9 GB | ||
| EGAF00006566608 | bam | 19.7 GB | ||
| EGAF00006566609 | bam | 2.7 GB | ||
| EGAF00006566610 | bam | 5.8 GB | ||
| EGAF00006566611 | bam | 7.6 GB | ||
| EGAF00006566612 | bam | 22.4 GB | ||
| EGAF00006566613 | bam | 26.9 GB | ||
| EGAF00006566614 | bam | 25.0 GB | ||
| EGAF00006566615 | bam | 29.4 GB | ||
| EGAF00006566616 | bam | 62.7 GB | ||
| EGAF00006566617 | bam | 8.2 GB | ||
| EGAF00006566618 | bam | 51.5 GB | ||
| 42 Files (796.7 GB) | ||||