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ESR1 mutations in tamoxifen-associated endometrial cancer versus spontaneous arisen endometrial tumors

An increased incidence of endometrial cancer has been described for patients that have received tamoxifen to treat breast cancer. Using samples from endometrial tumors, isolated from surgivcal specimens of patients who previously received tamoxifen treatment for breast cancer, we aimed to identify whether there are specific somatic mutations enriched in this population, relative to endometrial tumors from the general population. For this, WES was performed on matched endometrial tumors and healthy tissue (n=21).

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006566577 1658492121551 20.5 GB
EGAF00006566578 1658498421057 55.6 GB
EGAF00006566579 1658490322377 8.0 GB
EGAF00006566580 1658494821266 12.3 GB
EGAF00006566581 1658490322377 10.6 GB
EGAF00006566582 1658493021279 20.8 GB
EGAF00006566583 1658494821266 12.0 GB
EGAF00006566584 1658491221388 15.9 GB
EGAF00006566585 1658492121551 13.4 GB
EGAF00006566586 1658493021279 27.3 GB
EGAF00006566587 1658492121551 10.1 GB
EGAF00006566588 1658492121551 19.9 GB
EGAF00006566589 1658490322377 8.6 GB
EGAF00006566590 1658499321101 61.6 GB
EGAF00006566591 1658492121551 7.7 GB
EGAF00006566592 1658492121551 11.1 GB
EGAF00006566593 1658491221388 11.0 GB
EGAF00006566594 1658492121551 11.3 GB
EGAF00006566595 1658490322377 3.7 GB
EGAF00006566596 1658490322377 4.1 GB
EGAF00006566597 1658493921147 24.2 GB
EGAF00006566598 1658501121027 36.7 GB
EGAF00006566599 1658489436152 2.2 GB
EGAF00006566600 1658491221388 5.8 GB
EGAF00006566601 1658493021279 16.7 GB
EGAF00006566602 1658492121551 26.6 GB
EGAF00006566603 1658491221388 10.2 GB
EGAF00006566604 1658491221388 16.9 GB
EGAF00006566605 1658490322377 6.0 GB
EGAF00006566606 1658493021279 19.0 GB
EGAF00006566607 1658493021279 24.9 GB
EGAF00006566608 1658491221388 19.7 GB
EGAF00006566609 1658490322377 2.7 GB
EGAF00006566610 1658489436152 5.8 GB
EGAF00006566611 1658490322377 7.6 GB
EGAF00006566612 1658493021279 22.4 GB
EGAF00006566613 1658493921147 26.9 GB
EGAF00006566614 1658492121551 25.0 GB
EGAF00006566615 1658494821266 29.4 GB
EGAF00006566616 1658494821266 62.7 GB
EGAF00006566617 1658489436152 8.2 GB
EGAF00006566618 1658494821266 51.5 GB
42 Files (796.7 GB)