Need Help?

Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer.

This dataset consists of shallow whole genome sequencing data and amplicon sequencing data for 26 ovarian cancer patients (21 high-grade serous ovarian cancer, 4 low-grade serous ovarian cancer and 1 clear cell ovarian cancer). The data are provided as single end FASTQ files for the shallow whole genome sequencing data (31 libraries) and paired end FASTQ files for the amplicon sequencing data (98 libraries).

Request Access

Data Access policy - Brenton Lab

Data Access Request Form – Brenton Lab, CRUK-CI, University of Cambridge, UK These terms and conditions govern access to and use of the managed access datasets to which the User Institution has requested access. The User Institution and User agree to be bound by these terms and conditions. Definitions: Confidential Information: means any information provided by the Data Provider relating to the Data Data: The managed access dataset(s) to which the User Institution has requested access, as detailed in Schedule B. Data Provider: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE of The Old Schools, Trinity Lane, Cambridge CB2 1TN, United Kingdom and the Cambridge University Hospitals NHS Foundation Trust of Addenbrooke’s Hospital, Cambridge, CB2 0QQ; represented by staff of the Brenton Group at the Cancer Research UK Cambridge Institute, and contactable by email at james.brenton@cruk.cam.ac.uk or future email as updated; or future representatives as indicated in Data Access Committee(s) for the dataset(s) defined in Schedule B. Data Subject: means an individual who participated in research studies from whom the Data was derived. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Personal Data: means information and/or data about one or more living person who is the subject of personal data and who can be identified from that information, as provided under the General Data Protection Regulation (EU) 2016/679 (as amended from time to time), including but not limited to surname, initials, date of birth, address and postcodes, national insurance number, hospital number or NHS number. Project: The research project for which the User Institution has requested access to these Data, as defined in Schedule B. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. User Institution is referred to within this Agreement as “You” (and “Your” shall be construed accordingly). Data Provider will provide access to Data to the User Institution under the following Terms and Conditions: 1. You agree to preserve, at all times, the confidentiality and privacy of information and Data pertaining to Data Subjects. In particular, you undertake not to use, or attempt to use the Data to compromise or otherwise breach or infringe the confidentiality and privacy of information on Data Subjects. You agree to protect the confidentiality of Data Subjects in any Publications that you prepare by taking all reasonable care to limit the possibility of identification. You agree not to attempt to link Data to any other data source on the same samples, link the Data to any person or otherwise identify any Data Subject from the Data. 2. You agree not to transfer or disclose the Data, in whole or part, to others, except to persons within the User Institution for carrying out the Project or as reasonably necessary for Data/safety monitoring or programme management. If You wish to disclose the Data to a collaborator outside the User Institution, the third party must make a separate application for access to the Data. 3. You agree to use the Data for the advancement of medical research, and solely for the approved purpose and Project described in Schedule B and for no other purpose. 4. You agree that Data may be reissued from time to time, with suitable versioning. If the reissue is at the request of Data Subjects and/or other ethical scrutiny or concerns, you will destroy earlier versions of the Data, and upon request of Data Provider, provide written certification of such destruction. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 5. You agree to acknowledge in any Publication based in whole or part on the Data, the published paper(s) from which the Data derives, and the version of the Data. 6. You agree and acknowledge that the researchers of this study, the original Data creators, depositors, or copyright holders, and the Data Provider: a) bear no legal responsibility or liability for the accuracy or comprehensiveness of the Data, or from any use of the Data including further analysis or interpretation of such Data; and b) shall have no liability for any direct or indirect, consequential, or incidental damages or losses whatsoever arising out of Your use of the Data, or from the unavailability of, or lack of access to, the Data for whatever reason; and c) disclaim any and all representations, conditions or warranties (either express, implied or statutory) regarding the Data, including accuracy of the Data or that the Data corresponds with a particular description or is fit for a particular purpose. 7. You understand and acknowledge that the Data is owned by Data Provider and its collaborators and is protected by copyright, database rights and other intellectual property rights. You agree that you shall not reproduce or copy the Data, except as reasonably required to carry out the Project and for no other purpose, or sell all or any part of the Data in any circumstances. 8. You recognise that by granting You access to Data, no rights or ownership or intellectual property rights in or relating to the Data are transferred to You. 9. Upon any breach by You of the terms set out in this form, You will be required to destroy the Data in Your possession, and upon request, provide written certification to the Data Provider of such destruction. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 10. You accept that it may be necessary for the Data Provider to alter the terms of use of the Data from time to time. As an example, this may include specific provisions relating to the Data required by Data Provider or collaborator parties. In the event that changes are required, the Data Provider or their appointed agent will contact You to inform You of the changes and You may elect either to accept the changes or to destroy the Data in Your possession and cease its use. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 11. You agree that the Data is protected by and subject to applicable international laws. You are responsible for ensuring compliance with any such laws. The Data Provider reserves the right to request and inspect Your data security and management documentation to ensure the adequacy and compliance of data protection measures pertaining to storage and use of Data. 12. If the Data includes any identifiable Personal Data, You agree to: (a) take appropriate technical and organisational measures against the unauthorised or unlawful processing and/or use of the Data, any data derived from the Data and/or and all Confidential Information, against the accidental loss or destruction of, or damage to, such data and information. (b) ensure that the measures referred to in (a) shall include the measures set out in Schedule A. (c) restrict access to the Data, any data derived from the Data and all other Confidential Information to employees who strictly need access to such data and/or information to undertake the Project, and shall ensure that all such employees are reliable, and informed of the confidential nature of such data and/or information and the importance of processing it securely. (d) For the avoidance of doubt, You undertake not to disclose to a third party, whether in connection with the Project or otherwise, any data and/or information contained in or derived from the Data which constitutes Personal Data. Schedule A 1.1 You acknowledge and agree that the Data is pseudonymised Data and that You will become the Data Controller on receipt of such Data. 1.2 You will only process the Data for the purpose of carrying out the Project. 1.3 You agree that safeguards required under Article 89(1) of GDPR, and relevant conditions under the Data Protection Act 2018, are satisfied, and in particular that: (i) the processing of Data under or in connection with this Agreement is in the public interest; and (ii) if applicable, the Project has been subject to ethical review by an appropriate institutional review board or independent ethics committee. 1.4 The Data Provider does not intend to provide any information that may lead to You being able to identify any individual from whom any Data has been obtained. 1.5 You agree that You shall not analyse or make any use of any Data where it is reasonably foreseeable that such analysis or use may lead to the identification of any Data Subject or compromise the anonymity of any Data Subject in any way. 1.6 You shall notify the Data Provider immediately of any actual or suspected breach of security which involves the Data.   Schedule B Name of the applicant and co-applicant(s), including affiliations, titles and contact details. For dataset deposited at EGA, applicants must have registered accounts at EGA. Student applicants must include their supervisors as a co-applicant. Name of Registered User Email Job Title Supervisor* Title of Project (in less than 30 words) Data Requested (please indicate relevant publication(s) describing the data, accession number(s) and/or relevant links to data, and [where relevant] details of and links to the respective Data Access Committee(s) (DAC)) Research Project: Please provide a clear description of the project and its specific aims in no more than 750 words. This should include specific details of what you plan to do with the data and include key references. Brief description of the infrastructure and experience for handling the requested data securely Signature of authorized signatory of User Institution Signature: Name: Title: Date: Signature of Principal Investigator I confirm that I have read and understood the TERMS AND CONDITIONS as set forth in this DATA ACCESS REQUEST FORM. Signature: Name: Title: Date:

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001006200 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006143680 fq.gz 124.3 MB
EGAF00006143681 fq.gz 142.1 MB
EGAF00006143682 fq.gz 177.1 MB
EGAF00006143683 fq.gz 205.7 MB
EGAF00006143684 fq.gz 129.3 MB
EGAF00006143685 fq.gz 147.1 MB
EGAF00006143686 fq.gz 531.8 MB
EGAF00006143687 fq.gz 128.5 MB
EGAF00006143688 fq.gz 144.6 MB
EGAF00006143689 fq.gz 102.3 MB
EGAF00006143690 fq.gz 115.8 MB
EGAF00006143691 fq.gz 111.7 MB
EGAF00006143692 fq.gz 123.6 MB
EGAF00006143693 fq.gz 144.8 MB
EGAF00006143694 fq.gz 171.0 MB
EGAF00006143695 fq.gz 128.2 MB
EGAF00006143696 fq.gz 145.0 MB
EGAF00006143697 fq.gz 124.4 MB
EGAF00006143698 fq.gz 141.9 MB
EGAF00006143699 fq.gz 194.0 MB
EGAF00006143700 fq.gz 220.8 MB
EGAF00006143701 fq.gz 241.0 MB
EGAF00006143702 fq.gz 274.1 MB
EGAF00006143703 fq.gz 56.8 MB
EGAF00006143704 fq.gz 62.9 MB
EGAF00006143705 fq.gz 167.4 MB
EGAF00006143706 fq.gz 185.8 MB
EGAF00006143707 fq.gz 50.6 MB
EGAF00006143708 fq.gz 57.2 MB
EGAF00006143709 fq.gz 176.1 MB
EGAF00006143710 fq.gz 198.3 MB
EGAF00006143711 fq.gz 163.6 MB
EGAF00006143712 fq.gz 185.2 MB
EGAF00006143713 fq.gz 150.6 MB
EGAF00006143714 fq.gz 175.5 MB
EGAF00006143715 fq.gz 199.7 MB
EGAF00006143716 fq.gz 230.9 MB
EGAF00006143717 fq.gz 126.2 MB
EGAF00006143718 fq.gz 140.9 MB
EGAF00006143719 fq.gz 159.0 MB
EGAF00006143720 fq.gz 178.6 MB
EGAF00006143721 fq.gz 123.3 MB
EGAF00006143722 fq.gz 138.6 MB
EGAF00006143723 fq.gz 150.1 MB
EGAF00006143724 fq.gz 174.8 MB
EGAF00006143725 fq.gz 71.9 MB
EGAF00006143726 fq.gz 79.3 MB
EGAF00006143727 fq.gz 211.3 MB
EGAF00006143728 fq.gz 245.3 MB
EGAF00006143729 fq.gz 198.2 MB
EGAF00006143730 fq.gz 229.3 MB
EGAF00006143731 fq.gz 188.0 MB
EGAF00006143732 fq.gz 210.9 MB
EGAF00006143733 fq.gz 110.2 MB
EGAF00006143734 fq.gz 120.0 MB
EGAF00006143735 fq.gz 115.5 MB
EGAF00006143736 fq.gz 131.0 MB
EGAF00006143737 fq.gz 24.1 MB
EGAF00006143738 fq.gz 26.5 MB
EGAF00006143739 fq.gz 132.2 MB
EGAF00006143740 fq.gz 148.8 MB
EGAF00006143741 fq.gz 134.9 MB
EGAF00006143742 fq.gz 152.8 MB
EGAF00006143743 fq.gz 143.1 MB
EGAF00006143744 fq.gz 159.7 MB
EGAF00006143745 fq.gz 123.4 MB
EGAF00006143746 fq.gz 138.6 MB
EGAF00006143747 fq.gz 172.8 MB
EGAF00006143748 fq.gz 191.7 MB
EGAF00006143749 fq.gz 609.1 MB
EGAF00006143750 fq.gz 144.1 MB
EGAF00006143751 fq.gz 162.5 MB
EGAF00006143752 fq.gz 503.0 MB
EGAF00006143753 fq.gz 134.7 MB
EGAF00006143754 fq.gz 156.3 MB
EGAF00006143755 fq.gz 799.7 MB
EGAF00006143756 fq.gz 123.2 MB
EGAF00006143757 fq.gz 139.6 MB
EGAF00006143758 fq.gz 129.7 MB
EGAF00006143759 fq.gz 147.0 MB
EGAF00006143760 fq.gz 174.2 MB
EGAF00006143761 fq.gz 201.6 MB
EGAF00006143762 fq.gz 155.1 MB
EGAF00006143763 fq.gz 180.2 MB
EGAF00006143764 fq.gz 134.9 MB
EGAF00006143765 fq.gz 154.2 MB
EGAF00006143766 fq.gz 154.5 MB
EGAF00006143767 fq.gz 171.3 MB
EGAF00006143768 fq.gz 99.0 MB
EGAF00006143769 fq.gz 110.6 MB
EGAF00006143770 fq.gz 451.4 MB
EGAF00006143771 fq.gz 140.2 MB
EGAF00006143772 fq.gz 157.7 MB
EGAF00006143773 fq.gz 552.0 MB
EGAF00006143774 fq.gz 376.3 MB
EGAF00006143775 fq.gz 618.9 MB
EGAF00006143776 fq.gz 126.2 MB
EGAF00006143777 fq.gz 147.7 MB
EGAF00006143778 fq.gz 42.9 MB
EGAF00006143779 fq.gz 43.9 MB
EGAF00006143780 fq.gz 78.1 MB
EGAF00006143781 fq.gz 90.2 MB
EGAF00006143782 fq.gz 145.5 MB
EGAF00006143783 fq.gz 166.1 MB
EGAF00006143784 fq.gz 454.5 MB
EGAF00006143785 fq.gz 151.0 MB
EGAF00006143786 fq.gz 170.6 MB
EGAF00006143787 fq.gz 665.8 MB
EGAF00006143788 fq.gz 142.9 MB
EGAF00006143789 fq.gz 160.3 MB
EGAF00006143790 fq.gz 628.1 MB
EGAF00006143791 fq.gz 117.7 MB
EGAF00006143792 fq.gz 133.2 MB
EGAF00006143793 fq.gz 156.1 MB
EGAF00006143794 fq.gz 178.1 MB
EGAF00006143795 fq.gz 153.7 MB
EGAF00006143796 fq.gz 172.6 MB
EGAF00006143797 fq.gz 151.6 MB
EGAF00006143798 fq.gz 166.4 MB
EGAF00006143799 fq.gz 126.9 MB
EGAF00006143800 fq.gz 148.0 MB
EGAF00006143801 fq.gz 190.4 MB
EGAF00006143802 fq.gz 213.4 MB
EGAF00006143803 fq.gz 204.8 MB
EGAF00006143804 fq.gz 230.3 MB
EGAF00006143805 fq.gz 277.9 MB
EGAF00006143806 fq.gz 660.7 MB
EGAF00006143807 fq.gz 148.7 MB
EGAF00006143808 fq.gz 166.6 MB
EGAF00006143809 fq.gz 154.1 MB
EGAF00006143810 fq.gz 173.0 MB
EGAF00006143811 fq.gz 38.2 MB
EGAF00006143812 fq.gz 39.4 MB
EGAF00006143813 fq.gz 254.2 MB
EGAF00006143814 fq.gz 176.7 MB
EGAF00006143815 fq.gz 202.1 MB
EGAF00006143816 fq.gz 766.2 MB
EGAF00006143817 fq.gz 675.6 MB
EGAF00006143818 fq.gz 44.1 MB
EGAF00006143819 fq.gz 48.2 MB
EGAF00006143820 fq.gz 48.6 MB
EGAF00006143821 fq.gz 635.5 MB
EGAF00006143822 fq.gz 121.5 MB
EGAF00006143823 fq.gz 141.7 MB
EGAF00006143824 fq.gz 144.9 MB
EGAF00006143825 fq.gz 153.5 MB
EGAF00006143826 fq.gz 38.8 MB
EGAF00006143827 fq.gz 43.1 MB
EGAF00006143828 fq.gz 788.2 MB
EGAF00006143829 fq.gz 182.3 MB
EGAF00006143830 fq.gz 205.4 MB
EGAF00006143831 fq.gz 174.1 MB
EGAF00006143832 fq.gz 193.7 MB
EGAF00006143833 fq.gz 808.2 MB
EGAF00006143834 fq.gz 323.0 MB
EGAF00006143835 fq.gz 244.6 MB
EGAF00006143836 fq.gz 906.4 MB
EGAF00006143837 fq.gz 673.8 MB
EGAF00006143838 fq.gz 126.5 MB
EGAF00006143839 fq.gz 143.8 MB
EGAF00006143840 fq.gz 119.1 MB
EGAF00006143841 fq.gz 135.1 MB
EGAF00006143842 fq.gz 134.1 MB
EGAF00006143843 fq.gz 152.3 MB
EGAF00006143844 fq.gz 120.4 MB
EGAF00006143845 fq.gz 132.8 MB
EGAF00006143846 fq.gz 551.5 MB
EGAF00006143847 fq.gz 547.6 MB
EGAF00006143848 fq.gz 123.2 MB
EGAF00006143849 fq.gz 141.4 MB
EGAF00006143850 fq.gz 166.1 MB
EGAF00006143851 fq.gz 189.3 MB
EGAF00006143852 fq.gz 112.2 MB
EGAF00006143853 fq.gz 130.7 MB
EGAF00006143854 fq.gz 115.1 MB
EGAF00006143855 fq.gz 129.6 MB
EGAF00006143856 fq.gz 127.5 MB
EGAF00006143857 fq.gz 143.4 MB
EGAF00006143858 fq.gz 148.6 MB
EGAF00006143859 fq.gz 172.2 MB
EGAF00006143860 fq.gz 45.2 MB
EGAF00006143861 fq.gz 47.2 MB
EGAF00006143862 fq.gz 208.7 MB
EGAF00006143863 fq.gz 237.9 MB
EGAF00006143864 fq.gz 79.1 MB
EGAF00006143865 fq.gz 82.9 MB
EGAF00006143866 fq.gz 676.9 MB
EGAF00006143867 fq.gz 112.8 MB
EGAF00006143868 fq.gz 122.4 MB
EGAF00006143869 fq.gz 176.1 MB
EGAF00006143870 fq.gz 203.3 MB
EGAF00006143871 fq.gz 220.4 MB
EGAF00006143872 fq.gz 247.5 MB
EGAF00006143873 fq.gz 139.6 MB
EGAF00006143874 fq.gz 160.4 MB
EGAF00006143875 fq.gz 230.1 MB
EGAF00006143876 fq.gz 262.4 MB
EGAF00006143877 fq.gz 187.0 MB
EGAF00006143878 fq.gz 213.4 MB
EGAF00006143879 fq.gz 170.6 MB
EGAF00006143880 fq.gz 185.1 MB
EGAF00006143881 fq.gz 174.2 MB
EGAF00006143882 fq.gz 194.6 MB
EGAF00006143883 fq.gz 139.1 MB
EGAF00006143884 fq.gz 157.6 MB
EGAF00006143885 fq.gz 151.6 MB
EGAF00006143886 fq.gz 169.1 MB
EGAF00006143887 fq.gz 195.5 MB
EGAF00006143888 fq.gz 225.4 MB
EGAF00006143889 fq.gz 208.9 MB
EGAF00006143890 fq.gz 238.6 MB
EGAF00006143891 fq.gz 464.5 MB
EGAF00006143892 fq.gz 200.0 MB
EGAF00006143893 fq.gz 227.5 MB
EGAF00006143894 fq.gz 160.2 MB
EGAF00006143895 fq.gz 187.0 MB
EGAF00006143896 fq.gz 155.8 MB
EGAF00006143897 fq.gz 180.1 MB
EGAF00006143898 fq.gz 664.8 MB
EGAF00006143899 fq.gz 503.2 MB
EGAF00006143900 fq.gz 619.5 MB
EGAF00006143901 fq.gz 196.5 MB
EGAF00006143902 fq.gz 222.2 MB
EGAF00006143903 fq.gz 99.8 MB
EGAF00006143904 fq.gz 109.1 MB
EGAF00006143905 fq.gz 119.6 MB
EGAF00006143906 fq.gz 135.8 MB
227 Files (46.7 GB)