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RNA-Seq FASTQs for Tang F. et al. Chromatin accessibility profiles of castration-resistant prostate cancers reveal novel subtypes and therapeutic vulnerabilities

This dataset contains the FASTQ files for a portion of the samples in Tang F. et al. “Chromatin accessibility profiles of castration-resistant prostate cancers reveal novel subtypes and therapeutic vulnerabilities” published in Science. It contains 51 samples sequenced with Illumina HiSeq 2500 or HiSeq 4000. The remaining samples can be found at dbGaP: phs000909.v1.p1

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Chromatin profiles in prostate cancer - Data access policy This dataset is provided to You in accordance to the policy terms.

1. You, the Data Recipient, agree to only use the Data for the Purpose of the Project. 2. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. You undertake not to use or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 3. You agree not to attempt to identify Data Subjects. 4. You and your Authorised Personnel agree to take into consideration any usage restrictions (if any), stemming from consent, i.e. the appropriate lawful basis for processing the Data, as well as any usage restrictions stemming from any applicable internal policies of your Institution. 5. You agree that in handling this Data You will follow an up-to-date information technology (IT) policy that must include, at a minimum, the following items: a. Logging and auditing of Access to the Data and to the computer network; b. Password protection to computer network and/or strong data encryption; c. Virus and malware protection to computers on the computer network; d. Secure backup procedure; 6. You acknowledge that Access to the Data is granted for the duration of the Project described in Section I, as well as any new Project under the same research field or area. Any use of the Data for a Project of another research field or area will need to be approved under a new Agreement. 7. You recognize that nothing in this Agreement shall operate to transfer to You any intellectual property rights to the Data. 8. You agree not to make intellectual property claims on the Data and not to use intellectual property protection in ways that would prevent or block Access to, or use of, any element of the Data. 9. You can elect to perform further Research that would add intellectual and resource capital to the Data, and decide to obtain intellectual property rights on these downstream discoveries. In this case, You agree to implement licensing policies that will not obstruct further Research, following the Organisation for Economic Co-operation and Development Guidelines. 10. You agree that the Research Project 1) bears no legal responsibility for the accuracy or comprehensiveness of the Data; 2) accepts no liability for indirect, consequential, or incidental damages or losses arising from use of the Data; and 3) bears no responsibility for the further analysis or interpretation of these Data over and above that published by the Controller(s). 11. You agree to hold the Data Subject(s) and Data Controller(s) harmless and to defend and indemnify all these parties against all liabilities, demands, damages, expenses, and losses arising out of Your use for any Purpose of the Data. 12. You agree to a moratorium on publishing global analyses of the dataset until the Data Controller(s) have published their own global analysis or twelve (12) months, the maximum, have passed from the time the Data were deposited, whichever occurs first. You acknowledge that prompt publication or public disclosure of the results of the Research Project is encouraged. You also agree that by publishing Your global analyses of the Data, you will not disclose any results generated from the Data. 13. You agree to acknowledge the contribution of the Data Controller(s) in all oral and written presentations, disclosures, and Publications resulting from all analyses of the Data. 14. You agree to use the Data in Your laboratory. Any Authorised Personnel shall work under Your direct supervision. You agree to distribute a copy of these terms to the Authorised Personnel. 15. You may not transfer any information included in the Data to anyone unless specifically designated in the Research Project, or by prior specific or general written authorisation of the Data Controller(s) responsible for the generation of the original Data in each case. 16. You may not transfer the Data itself to anyone outside the Institution, unless the Controller(s) has (have) approved such transfer and its terms in writing. 17. Should You wish to share the Data with an external collaborator, the external collaborator must complete a separate Data Access Agreement. 18. You shall ensure that ‘all’ who have Access to the Data, namely You and Your Authorised Personnel, will be listed out, and are made aware and be bound by the terms of this Agreement. You remain solely and fully responsible for Your Authorised Personnel’s non-compliance with the provision of the Agreement and/or applicable laws. 19. In case of a breach of security resulting from ‘accidental’ use of Data by You and Your Authorised Personnel, which leads to disclosure of Data, then You must report this to Data Controller(s) within 72 hours maximum, and follow any relevant rule as provided by the GDPR. 20. In case of a ‘non-accidental or minor’ breach of the harmonized Data Access Agreement (hDAA) by You, You will further be required to destroy any Data held. 21. You accept that this Agreement will terminate immediately upon ‘any’ breach by You, or its termination (see Section I). 22. You endeavour to settle any dispute with the Data Controller(s) amicably. If you are unable to reach an Agreement, you will meet and negotiate in good faith in an effort to resolve the issue. If the issue has not been resolved within a reasonable period (e.g. 30 calendar days), you are both entitled to submit it for resolution by an arbitrator. 23. Further, the language of the proceedings will be ‘English’ if not otherwise agreed. The award of the arbitration will be final and binding upon the parties concerned.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00006011489 1645917183898 2.0 GB
EGAF00006011490 1645917183898 2.1 GB
EGAF00006011491 1645917183898 2.1 GB
EGAF00006011492 1645917183898 2.1 GB
EGAF00006011493 1645917183898 2.2 GB
EGAF00006011494 1645917183898 2.2 GB
EGAF00006011495 1645917183898 2.1 GB
EGAF00006011496 1645917183898 2.4 GB
EGAF00006011497 1645917183898 2.1 GB
EGAF00006011498 1645917183898 2.3 GB
EGAF00006011499 1645917183898 2.0 GB
EGAF00006011500 1645917183898 2.3 GB
EGAF00006011501 1645917183898 2.4 GB
EGAF00006011502 1645917183898 2.6 GB
EGAF00006011503 1645917183898 2.0 GB
EGAF00006011504 1645917183898 2.0 GB
EGAF00006011505 1645917183898 1.9 GB
EGAF00006011506 1645917183898 1.9 GB
EGAF00006011507 1645917183898 2.2 GB
EGAF00006011508 1645917183898 2.4 GB
EGAF00006011621 1645917183898 1.9 GB
EGAF00006011622 1645917183898 1.9 GB
EGAF00006011623 1645917183898 3.2 GB
EGAF00006011624 1645917183898 3.2 GB
EGAF00006011625 1645917183898 3.8 GB
EGAF00006011626 1645917183898 4.0 GB
EGAF00006011655 1645917183898 2.2 GB
EGAF00006011656 1645917183898 2.3 GB
EGAF00006011657 1645917183898 2.5 GB
EGAF00006011658 1645917183898 2.6 GB
EGAF00006011673 1645917183898 2.8 GB
EGAF00006011674 1645917183898 2.6 GB
EGAF00006011675 1645917183898 1.9 GB
EGAF00006011676 1645917183898 1.9 GB
EGAF00006011677 1645917183898 1.9 GB
EGAF00006011678 1645917183898 1.9 GB
EGAF00006011679 1645917183898 2.0 GB
EGAF00006011680 1645917183898 2.1 GB
EGAF00006011681 1645917183898 2.1 GB
EGAF00006011682 1645917183898 2.1 GB
EGAF00006011683 1645917183898 2.4 GB
EGAF00006011684 1645917183898 2.5 GB
EGAF00006011685 1645917183898 2.6 GB
EGAF00006011686 1645917183898 2.6 GB
EGAF00006011687 1645917183898 1.8 GB
EGAF00006011688 1645917183898 1.9 GB
EGAF00006011689 1645917183898 2.7 GB
EGAF00006011690 1645917183898 2.8 GB
EGAF00006011691 1645917183898 2.1 GB
EGAF00006011692 1645917183898 2.1 GB
EGAF00006011693 1645917183898 2.0 GB
EGAF00006011694 1645917183898 2.1 GB
EGAF00006011695 1645917183898 2.0 GB
EGAF00006011696 1645917183898 2.0 GB
EGAF00006011697 1645917183898 2.7 GB
EGAF00006011698 1645917183898 2.7 GB
EGAF00006011699 1645917183898 2.6 GB
EGAF00006011700 1645917385083 2.7 GB
EGAF00006011701 1645917385083 2.9 GB
EGAF00006011702 1645917385083 2.9 GB
EGAF00006011703 1645917385083 1.7 GB
EGAF00006011704 1645917385083 1.8 GB
EGAF00006011705 1645917385083 2.4 GB
EGAF00006011706 1645917385083 2.5 GB
EGAF00006011707 1645917385083 1.9 GB
EGAF00006011708 1645917385083 2.0 GB
EGAF00006011709 1645917385083 3.0 GB
EGAF00006011710 1645917385083 3.0 GB
EGAF00006011711 1645917385083 2.8 GB
EGAF00006011712 1645917385083 2.9 GB
EGAF00006011713 1645917385083 1.6 GB
EGAF00006011714 1645917385083 1.7 GB
EGAF00006011715 1645917385083 2.1 GB
EGAF00006011716 1645917385083 2.1 GB
EGAF00006011717 1645917385083 2.3 GB
EGAF00006011718 1645917385083 2.4 GB
EGAF00006011719 1645917385083 2.1 GB
EGAF00006011720 1645917385083 2.1 GB
EGAF00006011721 1645917385083 1.7 GB
EGAF00006011722 1645917385083 1.7 GB
EGAF00006011723 1645917385083 2.6 GB
EGAF00006011724 1645917385083 2.7 GB
EGAF00006011725 1645917385083 1.7 GB
EGAF00006011726 1645917385083 1.8 GB
EGAF00006011729 1645917385083 2.1 GB
EGAF00006011730 1645917385083 2.2 GB
EGAF00006011731 1645917385083 1.9 GB
EGAF00006011732 1645917385083 1.9 GB
EGAF00006011733 1645917385083 2.4 GB
EGAF00006011734 1645917385083 2.5 GB
EGAF00006011735 1645917385083 1.3 GB
EGAF00006011736 1645917385083 1.4 GB
EGAF00006011739 1645917385083 2.0 GB
EGAF00006011740 1645917385083 2.0 GB
EGAF00006011741 1645917385083 1.8 GB
EGAF00006011742 1645917385083 1.8 GB
EGAF00006011747 1645917385083 2.0 GB
EGAF00006011748 1645917385083 2.0 GB
EGAF00006011749 1645917385083 1.9 GB
EGAF00006011750 1645917385083 2.0 GB
EGAF00006011751 1645917385083 1.9 GB
EGAF00006011752 1645917385083 2.0 GB
102 Files (227.9 GB)