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LSC RNA-Sequencing

To infer the proteomic Mito signature in the LSC subcompartiment, myeloid blasts for 10 patients from the discovery cohort were FACS-sorted into CD34-GPR56+NKG2DLigands- (CD34-), alias 61dc5fb798e2520001702c03 CD34+GPR56+NKG2DLigands- (CD34+), alias 61dc5fb798e2520001702c03 Detailed gating strategy will be described in Donato, Correia, Andresen and Trumpp et al., (manuscript in preparation)

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DAP for genomic sequencing data generated as part of the "AML proteogenomic landscape" paper.

In requesting access to and retrieving data from this repository: 1. You agree to use the Data only for the advancement of medical research, according to the consent obtained from sample donors. 2. You agree not to use the data or any part thereof for the creation of products for sale or for any commercial purpose. 3. You agree to preserve, at all times, the confidentiality of information and Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy. 4. You agree not to attempt to link the data provided under this agreement to other information or archive data available for the data sets provided, even if access to that data has been formally granted to you, or it is freely available without restriction, without specific permission being sought from the relevent access committees. 5. You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others, except as necessary for data/safety monitoring or programme management. Should You wish to share the Data with a collaborator outwith the same Institution, the third party must make a separate application for access to the Data. 6. You agree to use the data for the approved purpose and project described in your application; use of the data for a new purpose or project will require a new application and approval. 7. You accept that Data will be reissued from time to time, with suitable versioning. If the reissue is at the request of sample donors and/or other ethical scrutiny, You will destroy earlier versions of the Data. 9. You agree to acknowledge in any work based in whole or part on the Data, the published paper from which the Data derives, the version of the data, and the role of the authors and the relevant primary collectors and their funders. Suitable wording is provided upon request. 10. You accept that the authors, represented by the data accessing committee, the original data creators, depositors or copyright holders, or the funders of the Data or any part of the Data supplied: a) bear no legal responsibility for the accuracy or comprehensiveness of the Data; and b) accept no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason. 11. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted. 12. You recognise that nothing in this agreement shall operate to transfer to the User Institution any intellectual property rights relating to the Data. The User Institution has the right to develop intellectual property based on comparisons with their own data. 13. You accept that this agreement will terminate immediately upon any breach of this agreement by You and You will be required to destroy any Data held. 14. You accept that it may be necessary for the authors, represented by the data accessing committee, or its appointed agent to alter the terms of this agreement from time to time in order to address new concerns. In this event, the authors, represented by the data accessing committee, or its appointed agent will contact You to inform You of any changes and You agree that Your continued use of the Data shall be dependent on the parties entering into a new version of the Agreement. 15. You agree that you will submit a report to the Data Access Committee, if requested, on completion of the agreed purpose. The Data Access Committee agrees to treat the report and all information, data, results, and conclusions contained within such report as confidential information belonging to the User Institution. 16. You accept that the Data is protected by and subject to international laws, including but not limited to the “Gendiagnostikgesetzt”, the EU General Data Protection Regulation (GDPR), and that You are responsible for ensuring compliance with any such applicable law. The Consortium Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures in countries that have no national laws comparable to that which pertain in the EU. 17. This agreement shall be construed, interpreted and governed by the laws of the Federal Republic of Germany and the European Union and shall be subject to the non-exclusive jurisdiction of the german and european courts.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005777518 1642756205657 770.4 MB
EGAF00005777519 1642757223730 755.7 MB
EGAF00005777520 1642757291908 3.1 GB
EGAF00005777521 1642756867679 3.1 GB
EGAF00005777522 1642756502289 1.7 GB
EGAF00005777523 1642756441979 1.7 GB
EGAF00005777524 1642756264683 1.3 GB
EGAF00005777525 1642756683301 1.2 GB
EGAF00005777526 1642756749219 2.6 GB
EGAF00005777527 1642757223730 2.5 GB
EGAF00005777528 1642757162610 3.2 GB
EGAF00005777529 1642757291908 3.2 GB
EGAF00005777530 1642759021104 3.4 GB
EGAF00005777531 1642756922118 3.3 GB
EGAF00005777532 1642756988666 1.7 GB
EGAF00005777533 1642757109771 1.6 GB
EGAF00005777534 1642758070420 2.3 GB
EGAF00005777535 1642757586339 2.3 GB
EGAF00005777536 1642758124299 2.5 GB
EGAF00005777537 1642759474149 2.5 GB
EGAF00005777538 1642756683301 2.1 GB
EGAF00005777539 1642756562159 2.0 GB
EGAF00005777540 1642756683301 1.6 GB
EGAF00005777541 1642757223730 1.6 GB
EGAF00005777542 1642756622809 1.8 GB
EGAF00005777543 1642756683301 1.8 GB
EGAF00005777544 1642756802938 1.9 GB
EGAF00005777545 1642757762150 1.9 GB
EGAF00005777546 1642757109771 2.1 GB
EGAF00005777547 1642757109771 2.0 GB
EGAF00005777548 1642756988666 2.8 GB
EGAF00005777549 1642757109771 2.7 GB
EGAF00005777550 1642756382663 1.3 GB
EGAF00005777551 1642757521366 1.3 GB
EGAF00005777552 1642757109771 1.3 GB
EGAF00005777553 1642756802938 1.3 GB
EGAF00005777554 1642757109771 2.5 GB
EGAF00005777555 1642759080921 2.4 GB
EGAF00005777556 1642756264683 1.0 GB
EGAF00005777557 1642756502289 1.0 GB
40 Files (81.1 GB)