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T-cell reconstitution after reduced dose ATLG induction in kidney transplant patients

We analyzed the T-cell receptor (TCR) repertoires from ten kidney transplant recipients. Five out of the ten kidney transplant recipients received ATLG while the other five recipients received basiliximab as induction therapy. TCR repertoires of CD4+ and CD8+ positive T-cells were assessed prior to transplantation and within the first month after transplantation as well as at three- and 12-months post-transplant. In addition, the pre-formed alloreactive TCR repertoire for each kidney transplant recipient was identified using mixed lymphocyte reaction and donor reactive T-cells were subjected to TCR beta sequencing. This dataset comprises a total of 106 samples. NGS TCR beta libraries of all samples were sequenced on an Illumina NextSeq 500 and raw sequencing data (in the form of fastq files) as well assembled clonotypes and their counts (in the form of clonotype tables) are provided.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005298863 1621088052562 360.8 MB
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EGAF00005298875 1621088537250 979.1 MB
EGAF00005298876 1621088600713 1.5 GB
EGAF00005298881 1621088361059 342.6 MB
EGAF00005298882 1621088112913 511.1 MB
EGAF00005298885 1621087816323 429.8 MB
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EGAF00005298894 1621088052562 360.4 MB
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EGAF00005298899 1621087870882 242.9 MB
EGAF00005298900 1621088178459 376.0 MB
EGAF00005298911 1621088178459 418.6 MB
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EGAF00005298916 1621087936428 482.5 MB
EGAF00005298931 1621087870882 425.7 MB
EGAF00005298932 1621087870882 678.3 MB
EGAF00005298933 1621088361059 350.0 MB
EGAF00005298934 1621088292990 526.7 MB
EGAF00005298935 1621088234103 379.9 MB
EGAF00005298936 1621088112913 604.5 MB
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EGAF00005298993 1621088000103 243.7 MB
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EGAF00005299085 1621087696797 4.3 MB
EGAF00005299086 1621087696797 271.3 kB
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EGAF00005774623 1642176304520 186.9 MB
EGAF00005774624 1642176245147 231.6 MB
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EGAF00005774631 1642176245147 170.8 MB
EGAF00005774632 1642176245147 232.1 MB
EGAF00005774633 1642176245147 205.7 MB
EGAF00005774634 1642176245147 287.8 MB
EGAF00005774635 1642176245147 219.9 MB
EGAF00005774636 1642176245147 288.8 MB
EGAF00005774637 1642176245147 239.3 MB
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EGAF00005774642 1642176360203 335.2 MB
EGAF00005774643 1642176304520 394.0 MB
EGAF00005774644 1642176600177 470.5 MB
EGAF00005774645 1642176245147 164.2 MB
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EGAF00005774647 1642176183006 28.2 MB
EGAF00005774648 1642176183006 36.3 MB
EGAF00005774649 1642176245147 347.5 MB
EGAF00005774650 1642176245147 411.0 MB
EGAF00005774651 1642176420188 54.1 MB
EGAF00005774652 1642176245147 70.1 MB
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EGAF00005774654 1642176304520 755.3 MB
EGAF00005774655 1642176660156 215.4 MB
EGAF00005774656 1642176245147 265.6 MB
EGAF00005774657 1642176360203 323.5 MB
EGAF00005774658 1642176245147 390.6 MB
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EGAF00005774663 1642176245147 107.8 MB
EGAF00005774664 1642176480052 129.5 MB
EGAF00005774665 1642176540094 321.1 MB
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EGAF00005774685 1642176245147 69.9 MB
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EGAF00005774687 1642176245147 73.2 MB
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EGAF00005774697 1642176245147 183.0 MB
EGAF00005774698 1642176245147 229.7 MB
EGAF00005774699 1642176304520 344.3 MB
EGAF00005774700 1642176245147 418.2 MB
EGAF00005774701 1642176420188 378.3 MB
EGAF00005774702 1642176245147 485.5 MB
EGAF00005774703 1642176245147 359.8 MB
EGAF00005774704 1642176245147 451.5 MB
EGAF00005774705 1642176245147 168.7 MB
EGAF00005774706 1642176245147 213.8 MB
EGAF00005774707 1642176245147 317.3 MB
EGAF00005774708 1642176360203 368.5 MB
EGAF00005774709 1642176245147 299.5 MB
EGAF00005774710 1642176540094 384.7 MB
EGAF00005774711 1642176183006 211.0 MB
EGAF00005774712 1642176304520 263.1 MB
EGAF00005774713 1642176245147 135.6 MB
EGAF00005774714 1642176183006 160.1 MB
EGAF00005774715 1642176183006 4.2 MB
EGAF00005774716 1642176183006 4.8 MB
EGAF00005774717 1642176245147 474.4 MB
EGAF00005774718 1642176304520 602.5 MB
EGAF00005774719 1642176245147 159.2 MB
EGAF00005774720 1642176183005 192.9 MB
EGAF00005774721 1642176360203 1.3 GB
EGAF00005774722 1642176720046 1.7 GB
EGAF00005774723 1642176183005 258.3 MB
EGAF00005774724 1642176245147 316.1 MB
EGAF00005774725 1642176183006 50.2 MB
EGAF00005774726 1642176420188 67.5 MB
EGAF00005774727 1642176183006 239.7 MB
EGAF00005774728 1642176245147 301.7 MB
EGAF00005774729 1642176183006 214.9 MB
EGAF00005774730 1642176245147 267.4 MB
EGAF00005774731 1642176183006 73.4 MB
EGAF00005774732 1642176183006 96.6 MB
EGAF00005774733 1642176245147 248.9 MB
EGAF00005774734 1642176245147 314.2 MB
EGAF00005774735 1642176183005 53.2 MB
EGAF00005774736 1642176183005 64.1 MB
EGAF00005774737 1642176183005 57.3 MB
EGAF00005774738 1642176183005 71.3 MB
EGAF00005774739 1642176304520 129.2 MB
EGAF00005774740 1642176245147 153.0 MB
EGAF00005774741 1642176245147 199.8 MB
EGAF00005774742 1642176245147 260.7 MB
EGAF00005774743 1642176183005 130.2 MB
EGAF00005774744 1642176245147 156.7 MB
EGAF00005774745 1642176245147 147.9 MB
EGAF00005774746 1642176304520 188.0 MB
EGAF00005774747 1642176183005 30.1 MB
EGAF00005774748 1642176183005 34.1 MB
EGAF00005774749 1642176183005 4.0 MB
EGAF00005774750 1642176245147 4.5 MB
EGAF00005774751 1642176245147 205.7 MB
EGAF00005774752 1642176304520 262.1 MB
EGAF00005774753 1642176183005 95.1 MB
EGAF00005774754 1642176183005 114.1 MB
EGAF00005774755 1642176245147 194.5 MB
EGAF00005774756 1642176304520 254.6 MB
EGAF00005774757 1642176245147 185.2 MB
EGAF00005774758 1642176245147 227.5 MB
EGAF00005774759 1642176600177 245.8 MB
EGAF00005774760 1642176245147 296.7 MB
EGAF00005774761 1642176245147 204.6 MB
EGAF00005774762 1642176360203 264.3 MB
EGAF00005774763 1642176245147 255.8 MB
EGAF00005774764 1642176245147 325.4 MB
EGAF00005774765 1642176183005 18.4 MB
EGAF00005774766 1642176183005 22.4 MB
EGAF00005774767 1642176183005 39.0 MB
EGAF00005774768 1642176420188 44.5 MB
EGAF00005774769 1642176245147 321.1 MB
EGAF00005774770 1642176245147 392.7 MB
EGAF00005774771 1642176304520 242.7 MB
EGAF00005774772 1642176420188 314.7 MB
EGAF00005774773 1642176183005 70.9 MB
EGAF00005774774 1642176245147 85.0 MB
EGAF00005774775 1642176245147 56.2 MB
EGAF00005774776 1642176183005 71.2 MB
EGAF00005774777 1642176183005 35.9 MB
EGAF00005774778 1642176183005 46.9 MB
EGAF00005774779 1642176183005 184.8 MB
EGAF00005774780 1642176245147 219.9 MB
EGAF00005774781 1642176304520 642.2 MB
EGAF00005774782 1642176304520 802.3 MB
EGAF00005774783 1642176245147 390.0 MB
EGAF00005774784 1642176540094 501.0 MB
EGAF00005774785 1642179903667 9.7 MB
EGAF00005774786 1642179903667 10.4 MB
EGAF00005774787 1642179960461 5.8 MB
EGAF00005774788 1642179903667 24.7 MB
EGAF00005774789 1642179903667 180.0 kB
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EGAF00005774793 1642179903667 3.8 MB
EGAF00005774794 1642179960461 9.5 kB
EGAF00005774795 1642179903667 8.2 MB
EGAF00005774796 1642179903667 16.1 MB
EGAF00005774797 1642179903667 7.8 MB
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EGAF00005774805 1642179903667 644.5 kB
EGAF00005774806 1642179903667 1.8 MB
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EGAF00005774808 1642179903667 1.4 MB
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EGAF00005774814 1642179903667 5.5 MB
EGAF00005774815 1642179903667 577.1 kB
EGAF00005774816 1642179903667 1.0 MB
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EGAF00005774820 1642179903667 373.1 kB
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EGAF00005774828 1642179903667 976.3 kB
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EGAF00005774831 1642179903667 13.7 MB
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EGAF00005774835 1642179903667 1.3 MB
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EGAF00005774864 1642183380313 1.8 MB
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EGAF00005774866 1642183380313 2.2 MB
EGAF00005774867 1642183380313 3.8 MB
EGAF00005774868 1642183380313 1.1 MB
318 Files (63.8 GB)