Need Help?

Genomic signatures define three subtypes of EGFR-mutant stage II-III non-small-cell lung cancer with distinct adjuvant therapy outcomes

This dataset contains targeted sequencing data of 204 surgical samples from resected NSCLC. Genomic profiling identifies five predictive biomarkers, which is then integrated into the Multiple-gene INdex to Evaluate the Relative benefit of Various Adjuvant therapies (MINERVA) score. The MINERVA score categorizes patients into three subgroups with relative disease-free survival and overall survival benefits from either adjuvant gefitinib or chemotherapy. This study demonstrates that predictive genomic signatures could potentially stratify resected EGFR-mutant NSCLC patients and provide precise guidance towards future personalized adjuvant therapy.

Request Access

This agreement governs the terms on which access will be granted to the genotype data generated by Guangdong Lung Cancer Institute. Please follow Data Availability statement of the study for data access.

The raw sequencing data are available under restricted access due to data privacy laws. Access can be obtained by contacting corresponding authors of this study at syylwu@live.cn.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005492424 1632945257992 4.1 MB
EGAF00005492425 1632944956146 1.9 MB
EGAF00005492426 1632945257992 3.1 MB
EGAF00005492427 1632957533880 3.5 MB
EGAF00005492428 1632945257992 2.2 MB
EGAF00005492429 1632945257992 2.8 MB
EGAF00005492430 1632945257992 1.5 MB
EGAF00005492431 1632957031165 2.9 MB
EGAF00005492432 1632945257992 3.9 MB
EGAF00005492433 1632945257992 2.7 MB
EGAF00005492434 1632945257992 3.2 MB
EGAF00005492435 1632945257992 2.0 MB
EGAF00005492436 1632957031165 2.4 MB
EGAF00005492437 1632945257992 3.0 MB
EGAF00005492438 1632945257992 2.1 MB
EGAF00005492439 1632945257992 4.7 MB
EGAF00005492440 1632945257992 4.3 MB
EGAF00005492441 1632945257992 4.1 MB
EGAF00005492442 1632945257992 4.3 MB
EGAF00005492443 1632957031165 4.1 MB
EGAF00005492444 1632945257992 2.2 MB
EGAF00005492445 1632945257992 5.5 MB
EGAF00005492446 1632945257992 2.1 MB
EGAF00005492447 1632945257992 1.8 MB
EGAF00005492448 1632945257992 3.0 MB
EGAF00005492449 1632945257992 3.6 MB
EGAF00005492450 1632945257992 1.8 MB
EGAF00005492451 1632945257992 3.5 MB
EGAF00005492452 1632945257992 4.2 MB
EGAF00005492453 1632945257992 2.4 MB
EGAF00005492454 1632945257992 5.6 MB
EGAF00005492455 1632945257992 928.1 kB
EGAF00005492456 1632945257992 2.0 MB
EGAF00005492457 1632945257992 1.6 MB
EGAF00005492458 1632945781330 3.3 MB
EGAF00005492459 1632945257992 2.8 MB
EGAF00005492460 1632945781330 2.7 MB
EGAF00005492461 1632945257992 2.9 MB
EGAF00005492462 1632971619059 4.0 MB
EGAF00005492463 1632945781331 1.8 MB
EGAF00005492464 1632945257992 5.3 MB
EGAF00005492465 1632945257992 2.3 MB
EGAF00005492466 1632945781331 2.9 MB
EGAF00005492467 1632945257992 4.3 MB
EGAF00005492468 1632945781330 2.2 MB
EGAF00005492469 1632945781331 2.5 MB
EGAF00005492470 1632945781330 3.0 MB
EGAF00005492471 1632945781330 2.6 MB
EGAF00005492472 1632945781331 2.9 MB
EGAF00005492473 1632946366958 2.4 MB
EGAF00005492474 1632945781331 6.4 MB
EGAF00005492475 1632957783165 4.2 MB
EGAF00005492476 1632945781330 3.1 MB
EGAF00005492477 1632945781331 1.8 MB
EGAF00005492478 1632945781330 2.1 MB
EGAF00005492479 1632945781331 1.8 MB
EGAF00005492480 1632945781330 5.9 MB
EGAF00005492481 1632945781330 1.9 MB
EGAF00005492482 1632957031165 1.5 MB
EGAF00005492483 1632945781331 1.3 MB
EGAF00005492484 1632945781331 2.1 MB
EGAF00005492485 1632945781330 644.9 kB
EGAF00005492486 1632945781330 3.0 MB
EGAF00005492487 1632945781330 1.9 MB
EGAF00005492488 1632946366958 3.6 MB
EGAF00005492489 1632945781330 2.7 MB
EGAF00005492490 1632946366958 1.9 MB
EGAF00005492491 1632957031165 2.7 MB
EGAF00005492492 1632945781330 2.1 MB
EGAF00005492493 1632945781330 1.8 MB
EGAF00005492494 1632945781330 2.3 MB
EGAF00005492495 1632946366958 2.4 MB
EGAF00005492496 1632946366958 4.0 MB
EGAF00005492497 1632945781330 993.8 kB
EGAF00005492498 1632945781331 3.0 MB
EGAF00005492499 1632945781331 2.5 MB
EGAF00005492500 1632945781331 1.5 MB
EGAF00005492501 1632946366958 3.4 MB
EGAF00005492502 1632945781331 1.7 MB
EGAF00005492503 1632945781331 1.9 MB
EGAF00005492504 1632945781331 1.3 MB
EGAF00005492505 1632946366958 5.4 MB
EGAF00005492506 1632945781331 2.0 MB
EGAF00005492507 1632945781331 2.4 MB
EGAF00005492508 1632946366958 2.8 MB
EGAF00005492509 1632945781331 4.6 MB
EGAF00005492510 1632945781331 1.6 MB
EGAF00005492511 1632945781330 4.9 MB
EGAF00005492512 1632957783165 3.3 MB
EGAF00005492513 1632945781331 2.2 MB
EGAF00005492514 1632957281688 2.8 MB
EGAF00005492515 1632945781331 3.2 MB
EGAF00005492516 1632945781331 1.9 MB
EGAF00005492517 1632957281688 3.7 MB
EGAF00005492518 1632946366958 2.2 MB
EGAF00005492519 1632946366958 2.2 MB
EGAF00005492520 1632946366958 2.8 MB
EGAF00005492521 1632945781331 2.6 MB
EGAF00005492522 1632946366958 3.3 MB
EGAF00005492523 1632946366958 2.8 MB
EGAF00005492524 1632957281688 2.0 MB
EGAF00005492525 1632946366959 2.3 MB
EGAF00005492526 1632946366959 2.6 MB
EGAF00005492527 1632946366959 2.6 MB
EGAF00005492528 1632946366959 4.8 MB
EGAF00005492529 1632946366959 2.8 MB
EGAF00005492530 1632946366959 3.7 MB
EGAF00005492531 1632946366959 3.3 MB
EGAF00005492532 1632946366959 4.2 MB
EGAF00005492533 1632946366958 4.3 MB
EGAF00005492534 1632946366958 3.0 MB
EGAF00005492535 1632946366958 1.3 MB
EGAF00005492536 1632957031165 1.7 MB
EGAF00005492537 1632946366958 2.7 MB
EGAF00005492538 1632946366958 2.3 MB
EGAF00005492539 1632945781331 5.0 MB
EGAF00005492540 1632946366958 7.5 MB
EGAF00005492541 1632946366958 3.7 MB
EGAF00005492542 1632946366958 2.2 MB
EGAF00005492543 1632946366958 4.1 MB
EGAF00005492544 1632946366959 2.4 MB
EGAF00005492545 1632946366959 1.7 MB
EGAF00005492546 1632957031165 2.6 MB
EGAF00005492547 1632946366959 2.9 MB
EGAF00005492548 1632946366959 1.6 MB
EGAF00005492549 1632946366959 2.8 MB
EGAF00005492550 1632957031165 3.9 MB
EGAF00005492551 1632946366959 9.5 MB
EGAF00005492552 1632946366959 2.8 MB
EGAF00005492553 1632957031165 1.6 MB
EGAF00005492554 1632946366959 4.8 MB
EGAF00005492555 1632946366959 2.4 MB
EGAF00005492556 1632946366959 1.9 MB
EGAF00005492557 1632946366959 2.0 MB
EGAF00005492558 1632946366959 4.0 MB
EGAF00005492559 1632946366959 3.6 MB
EGAF00005492560 1632946366959 4.1 MB
EGAF00005492561 1632946366959 2.2 MB
EGAF00005492562 1632946366959 1.9 MB
EGAF00005492563 1632946366959 2.6 MB
EGAF00005492564 1632946366959 2.4 MB
EGAF00005492565 1632957031165 2.0 MB
EGAF00005492566 1632946366959 988.4 kB
EGAF00005492567 1632946366959 5.7 MB
EGAF00005492568 1632946366958 3.5 MB
EGAF00005492569 1632946366959 2.7 MB
EGAF00005492570 1632946366959 3.6 MB
EGAF00005492571 1632957281688 4.3 MB
EGAF00005492572 1632946366959 3.7 MB
EGAF00005492573 1632946366959 5.2 MB
EGAF00005492574 1632946366959 3.4 MB
EGAF00005492575 1632946366959 4.0 MB
EGAF00005492576 1632957031165 5.9 MB
EGAF00005492577 1632946366959 1.8 MB
EGAF00005492578 1632946366959 3.5 MB
EGAF00005492579 1632946366959 2.1 MB
EGAF00005492580 1632946366959 1.9 MB
EGAF00005492581 1632946366959 5.1 MB
EGAF00005492582 1632946366959 3.8 MB
EGAF00005492583 1632946366959 1.5 MB
EGAF00005492584 1632946366959 3.5 MB
EGAF00005492585 1632946366959 4.4 MB
EGAF00005492586 1632946366959 2.7 MB
EGAF00005492587 1632946366959 3.5 MB
EGAF00005492588 1632946366959 1.8 MB
EGAF00005492589 1632946366959 2.1 MB
EGAF00005492590 1632946366959 428.3 kB
EGAF00005492591 1632946366958 3.8 MB
EGAF00005492592 1632946951096 3.6 MB
EGAF00005492593 1632946366959 2.0 MB
EGAF00005492594 1632946366958 3.8 MB
EGAF00005492595 1632946366958 1.9 MB
EGAF00005492596 1632946366959 4.0 MB
EGAF00005492597 1632946951096 6.7 MB
EGAF00005492598 1632957031165 3.2 MB
EGAF00005492599 1632946366959 2.0 MB
EGAF00005492600 1632946366959 5.0 MB
EGAF00005492601 1632946366959 3.4 MB
EGAF00005492602 1632957783165 1.7 MB
EGAF00005492603 1632946366959 1.3 MB
EGAF00005492604 1632946366959 1.9 MB
EGAF00005492605 1632958028872 1.7 MB
EGAF00005492606 1632946366959 2.7 MB
EGAF00005492607 1632946366959 3.6 MB
EGAF00005492608 1632946366959 1.6 MB
EGAF00005492609 1632946366959 5.0 MB
EGAF00005492610 1632946366959 6.7 MB
EGAF00005492611 1632957031165 2.8 MB
EGAF00005492612 1632946366959 3.3 MB
EGAF00005492613 1632946366959 2.5 MB
EGAF00005492614 1632946366959 3.9 MB
EGAF00005492615 1632946366959 3.9 MB
EGAF00005492616 1632946951096 2.0 MB
EGAF00005492617 1632946366959 2.4 MB
EGAF00005492618 1632946951096 2.6 MB
EGAF00005492619 1632946951096 3.5 MB
EGAF00005492620 1632946366959 1.8 MB
EGAF00005492621 1632946951096 3.0 MB
EGAF00005492622 1632946366959 5.8 MB
EGAF00005492623 1632946366959 2.8 MB
EGAF00005492624 1632946366959 2.5 MB
EGAF00005492625 1632946951096 2.5 MB
EGAF00005492626 1632946366959 2.3 MB
EGAF00005492627 1632957281688 2.2 MB
204 Files (612.8 MB)