Need Help?

sWGS of OV04 PDX samples for ACN rascal study

This dataset contains 148 .bam files of shallow WGS data (~0.1X) from OV04 PDX samples. Sequencing reads were aligned to the 1000 Genomes Project GRCh37-derived reference genome using the BWA aligner (v.0.07.17; CRUK-CI alignment pipeline).

Request Access

Data Access policy - Brenton Lab (OV04 study)

Data Access Request Form – Brenton Lab, CRUK-CI, University of Cambridge, UK These terms and conditions govern access to and use of the managed access datasets to which the User Institution has requested access. The User Institution and User agree to be bound by these terms and conditions. Definitions: Confidential Information: means any information provided by the Data Provider relating to the Data Data: The managed access dataset(s) to which the User Institution has requested access, as detailed in Schedule B. Data Provider: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE of The Old Schools, Trinity Lane, Cambridge CB2 1TN, United Kingdom and the Cambridge University Hospitals NHS Foundation Trust of Addenbrooke’s Hospital, Cambridge, CB2 0QQ; represented by staff of the Brenton Group at the Cancer Research UK Cambridge Institute, and contactable by email at james.brenton@cruk.cam.ac.uk or future email as updated; or future representatives as indicated in Data Access Committee(s) for the dataset(s) defined in Schedule B. Data Subject: means an individual who participated in research studies from whom the Data was derived. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Personal Data: means information and/or data about one or more living person who is the subject of personal data and who can be identified from that information, as provided under the General Data Protection Regulation (EU) 2016/679 (as amended from time to time), including but not limited to surname, initials, date of birth, address and postcodes, national insurance number, hospital number or NHS number. Project: The research project for which the User Institution has requested access to these Data, as defined in Schedule B. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. User Institution is referred to within this Agreement as “You” (and “Your” shall be construed accordingly). Data Provider will provide access to Data to the User Institution under the following Terms and Conditions: 1. You agree to preserve, at all times, the confidentiality and privacy of information and Data pertaining to Data Subjects. In particular, you undertake not to use, or attempt to use the Data to compromise or otherwise breach or infringe the confidentiality and privacy of information on Data Subjects. You agree to protect the confidentiality of Data Subjects in any Publications that you prepare by taking all reasonable care to limit the possibility of identification. You agree not to attempt to link Data to any other data source on the same samples, link the Data to any person or otherwise identify any Data Subject from the Data. 2. You agree not to transfer or disclose the Data, in whole or part, to others, except to persons within the User Institution for carrying out the Project or as reasonably necessary for Data/safety monitoring or programme management. If You wish to disclose the Data to a collaborator outside the User Institution, the third party must make a separate application for access to the Data. 3. You agree to use the Data for the advancement of medical research, and solely for the approved purpose and Project described in Schedule B and for no other purpose. 4. You agree that Data may be reissued from time to time, with suitable versioning. If the reissue is at the request of Data Subjects and/or other ethical scrutiny or concerns, you will destroy earlier versions of the Data, and upon request of Data Provider, provide written certification of such destruction. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 5. You agree to acknowledge in any Publication based in whole or part on the Data, the published paper(s) from which the Data derives, and the version of the Data. 6. You agree and acknowledge that the researchers of this study, the original Data creators, depositors, or copyright holders, and the Data Provider: a) bear no legal responsibility or liability for the accuracy or comprehensiveness of the Data, or from any use of the Data including further analysis or interpretation of such Data; and b) shall have no liability for any direct or indirect, consequential, or incidental damages or losses whatsoever arising out of Your use of the Data, or from the unavailability of, or lack of access to, the Data for whatever reason; and c) disclaim any and all representations, conditions or warranties (either express, implied or statutory) regarding the Data, including accuracy of the Data or that the Data corresponds with a particular description or is fit for a particular purpose. 7. You understand and acknowledge that the Data is owned by Data Provider and its collaborators and is protected by copyright, database rights and other intellectual property rights. You agree that you shall not reproduce or copy the Data, except as reasonably required to carry out the Project and for no other purpose, or sell all or any part of the Data in any circumstances. 8. You recognise that by granting You access to Data, no rights or ownership or intellectual property rights in or relating to the Data are transferred to You. 9. Upon any breach by You of the terms set out in this form, You will be required to destroy the Data in Your possession, and upon request, provide written certification to the Data Provider of such destruction. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 10. You accept that it may be necessary for the Data Provider to alter the terms of use of the Data from time to time. As an example, this may include specific provisions relating to the Data required by Data Provider or collaborator parties. In the event that changes are required, the Data Provider or their appointed agent will contact You to inform You of the changes and You may elect either to accept the changes or to destroy the Data in Your possession and cease its use. Your obligations as set out in this form pertaining to the Data and its use will continue to operate in full force and effect after Data is destroyed. 11. You agree that the Data is protected by and subject to applicable international laws. You are responsible for ensuring compliance with any such laws. The Data Provider reserves the right to request and inspect Your data security and management documentation to ensure the adequacy and compliance of data protection measures pertaining to storage and use of Data. 12. If the Data includes any identifiable Personal Data, You agree to: (a) take appropriate technical and organisational measures against the unauthorised or unlawful processing and/or use of the Data, any data derived from the Data and/or and all Confidential Information, against the accidental loss or destruction of, or damage to, such data and information. (b) ensure that the measures referred to in (a) shall include the measures set out in Schedule A. (c) restrict access to the Data, any data derived from the Data and all other Confidential Information to employees who strictly need access to such data and/or information to undertake the Project, and shall ensure that all such employees are reliable, and informed of the confidential nature of such data and/or information and the importance of processing it securely. (d) For the avoidance of doubt, You undertake not to disclose to a third party, whether in connection with the Project or otherwise, any data and/or information contained in or derived from the Data which constitutes Personal Data. Schedule A 1.1 You acknowledge and agree that the Data is pseudonymised Data and that You will become the Data Controller on receipt of such Data. 1.2 You will only process the Data for the purpose of carrying out the Project. 1.3 You agree that safeguards required under Article 89(1) of GDPR, and relevant conditions under the Data Protection Act 2018, are satisfied, and in particular that: (i) the processing of Data under or in connection with this Agreement is in the public interest; and (ii) if applicable, the Project has been subject to ethical review by an appropriate institutional review board or independent ethics committee. 1.4 The Data Provider does not intend to provide any information that may lead to You being able to identify any individual from whom any Data has been obtained. 1.5 You agree that You shall not analyse or make any use of any Data where it is reasonably foreseeable that such analysis or use may lead to the identification of any Data Subject or compromise the anonymity of any Data Subject in any way. 1.6 You shall notify the Data Provider immediately of any actual or suspected breach of security which involves the Data.   Schedule B Name of the applicant and co-applicant(s), including affiliations, titles and contact details. For dataset deposited at EGA, applicants must have registered accounts at EGA. Student applicants must include their supervisors as a co-applicant. Name of Registered User Email Job Title Supervisor* Title of Project (in less than 30 words) Data Requested (please indicate relevant publication(s) describing the data, accession number(s) and/or relevant links to data, and [where relevant] details of and links to the respective Data Access Committee(s) (DAC)) Research Project: Please provide a clear description of the project and its specific aims in no more than 750 words. This should include specific details of what you plan to do with the data and include key references. Brief description of the infrastructure and experience for handling the requested data securely Signature of authorized signatory of User Institution Signature: Name: Title: Date: Signature of Principal Investigator I confirm that I have read and understood the TERMS AND CONDITIONS as set forth in this DATA ACCESS REQUEST FORM. Signature: Name: Title: Date:

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001005601 Whole Genome Sequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005477028 bam 545.9 MB
EGAF00005477029 bam 805.3 MB
EGAF00005477030 bam 591.9 MB
EGAF00005477031 bam 944.3 MB
EGAF00005477032 bam 691.0 MB
EGAF00005477033 bam 582.9 MB
EGAF00005477034 bam 874.2 MB
EGAF00005477035 bam 816.0 MB
EGAF00005477037 bam 465.1 MB
EGAF00005477039 bam 692.8 MB
EGAF00005477040 bam 769.0 MB
EGAF00005477041 bam 543.9 MB
EGAF00005477042 bam 704.5 MB
EGAF00005477043 bam 635.8 MB
EGAF00005477044 bam 557.8 MB
EGAF00005477045 bam 496.6 MB
EGAF00005477046 bam 477.0 MB
EGAF00005477047 bam 563.2 MB
EGAF00005477048 bam 632.1 MB
EGAF00005477049 bam 538.1 MB
EGAF00005477050 bam 826.8 MB
EGAF00005477051 bam 694.6 MB
EGAF00005477052 bam 848.9 MB
EGAF00005477053 bam 764.0 MB
EGAF00005477054 bam 782.5 MB
EGAF00005477055 bam 503.2 MB
EGAF00005477056 bam 505.8 MB
EGAF00005477057 bam 680.3 MB
EGAF00005477058 bam 761.0 MB
EGAF00005477059 bam 463.5 MB
EGAF00005477060 bam 728.9 MB
EGAF00005477061 bam 452.9 MB
EGAF00005477062 bam 854.1 MB
EGAF00005477063 bam 736.3 MB
EGAF00005477064 bam 806.3 MB
EGAF00005477065 bam 551.3 MB
EGAF00005477066 bam 638.5 MB
EGAF00005477067 bam 929.1 MB
EGAF00005477068 bam 742.1 MB
EGAF00005477069 bam 487.5 MB
EGAF00005477070 bam 683.5 MB
EGAF00005477071 bam 748.9 MB
EGAF00005477072 bam 782.0 MB
EGAF00005477073 bam 585.7 MB
EGAF00005477074 bam 718.8 MB
EGAF00005477075 bam 570.3 MB
EGAF00005477076 bam 555.0 MB
EGAF00005477077 bam 594.9 MB
EGAF00005477078 bam 616.3 MB
EGAF00005477079 bam 660.3 MB
EGAF00005477080 bam 602.5 MB
EGAF00005477081 bam 779.1 MB
EGAF00005477082 bam 610.5 MB
EGAF00005477083 bam 638.3 MB
EGAF00005477084 bam 337.8 MB
EGAF00005477085 bam 433.1 MB
EGAF00005477086 bam 676.7 MB
EGAF00005477087 bam 496.5 MB
EGAF00005477088 bam 751.1 MB
EGAF00005477089 bam 665.8 MB
EGAF00005477090 bam 766.3 MB
EGAF00005477091 bam 606.8 MB
EGAF00005477092 bam 755.3 MB
EGAF00005477093 bam 741.0 MB
EGAF00005477094 bam 735.1 MB
EGAF00005477095 bam 1.0 GB
EGAF00005477096 bam 751.5 MB
EGAF00005477097 bam 733.3 MB
EGAF00005477098 bam 668.8 MB
EGAF00005477099 bam 586.1 MB
EGAF00005477100 bam 753.4 MB
EGAF00005477101 bam 612.7 MB
EGAF00005477102 bam 539.6 MB
EGAF00005477103 bam 718.6 MB
EGAF00005477105 bam 873.2 MB
EGAF00005477106 bam 845.6 MB
EGAF00005477107 bam 638.5 MB
EGAF00005477108 bam 815.3 MB
EGAF00005477109 bam 792.0 MB
EGAF00005477110 bam 827.7 MB
EGAF00005477111 bam 498.2 MB
EGAF00005477112 bam 626.4 MB
EGAF00005477113 bam 755.7 MB
EGAF00005477114 bam 437.6 MB
EGAF00005477115 bam 594.5 MB
EGAF00005477116 bam 597.5 MB
EGAF00005477117 bam 521.8 MB
EGAF00005477118 bam 572.8 MB
EGAF00005477119 bam 752.6 MB
EGAF00005477120 bam 807.2 MB
EGAF00005477121 bam 760.0 MB
EGAF00005477122 bam 675.9 MB
EGAF00005477123 bam 724.0 MB
EGAF00005477124 bam 1.0 GB
EGAF00005477125 bam 662.5 MB
EGAF00005477126 bam 905.4 MB
EGAF00005477127 bam 808.6 MB
EGAF00005477128 bam 853.4 MB
EGAF00005477129 bam 618.7 MB
EGAF00005477130 bam 738.4 MB
EGAF00005477131 bam 431.1 MB
EGAF00005477132 bam 840.7 MB
EGAF00005477133 bam 913.5 MB
EGAF00005477134 bam 940.4 MB
EGAF00005477135 bam 884.9 MB
EGAF00005477136 bam 679.7 MB
EGAF00005477137 bam 937.2 MB
EGAF00005477138 bam 767.4 MB
EGAF00005477140 bam 735.5 MB
EGAF00005477141 bam 1.0 GB
EGAF00005477142 bam 810.9 MB
EGAF00005477143 bam 821.1 MB
EGAF00005477144 bam 404.4 MB
EGAF00005477145 bam 658.1 MB
EGAF00005477146 bam 735.7 MB
EGAF00005477147 bam 748.7 MB
EGAF00005477148 bam 710.8 MB
EGAF00005477149 bam 583.3 MB
EGAF00005477150 bam 639.5 MB
EGAF00005477151 bam 648.0 MB
EGAF00005477152 bam 492.7 MB
EGAF00005477153 bam 926.1 MB
EGAF00005477154 bam 395.6 MB
EGAF00005477155 bam 628.2 MB
EGAF00005477156 bam 809.3 MB
EGAF00005477157 bam 899.9 MB
EGAF00005477158 bam 1.0 GB
EGAF00005477159 bam 635.7 MB
EGAF00005477160 bam 639.0 MB
EGAF00005477161 bam 786.9 MB
EGAF00005477162 bam 774.2 MB
EGAF00005477163 bam 890.0 MB
EGAF00005477164 bam 725.8 MB
EGAF00005477165 bam 620.7 MB
EGAF00005477166 bam 862.9 MB
EGAF00005477167 bam 432.6 MB
EGAF00005477168 bam 741.5 MB
EGAF00005477169 bam 742.6 MB
EGAF00005477170 bam 437.6 MB
EGAF00005477171 bam 652.1 MB
EGAF00005477172 bam 778.7 MB
EGAF00005477173 bam 810.0 MB
EGAF00005477174 bam 440.7 MB
EGAF00005477175 bam 737.9 MB
144 Files (99.7 GB)