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Single cell ATAC sequencing

Paired-end fastq files of 22 AML and 2 normal bone marrow samples were generated using 10x Genomics single cell ATAC sequencing following manufacturer's protocol (CG000168 User Guide RevB) for chemistry version 1.0 and targeting 10000 nuclei per sample. Libraries were sequenced using Illumina HiSeq4000 using recommended cycling parameters.

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Department of Genomic Medicine Data Access Agreement

DATA ACCESS AGREEMENT This Data Access Agreement (“Agreement”), effective as of the ____ day of _________________, 20__ (“Effective Date”), is by and between The University of Texas M. D. Anderson Cancer Center, an institution of The University of Texas System and an agency of the State of Texas, with an address at 1515 Holcombe Boulevard, Houston, Texas 77030 (“Provider”), and ________________________________ (“Recipient”) on behalf of its investigator _______ (“Recipient Investigator”) (collectively, the “Parties”; each, a “Party”). RECITALS Provider maintains the following de-identified data in the European Genome-phenome Archive (EGA) managed by the European Bioinformatics Institute ________________ (“Data”), and Provider is willing to allow Recipient to access such Data from the EGA for the internal noncommercial research purposes of _______________ (“Purpose”), pursuant to the terms of this Agreement. In consideration of the mutual promises and covenants herein, and for other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the Parties agree as follows: 1. The Data will be used solely for the Research by Recipient Investigator at Recipient, and may not be transferred to any other investigator or to any third party without prior written permission from Provider. The Material may not be used for any purpose other than the Research, including without limitation for any commercial purpose or for research in human subjects (including, without limitation, in diagnostic testing). 2. Neither Recipient nor Recipient Investigator shall disclose Data to any person or party other than the Recipient Investigator hereunder without Provider’s prior written consent. 3. The Data will be used in compliance with all applicable laws, regulations, and guidelines applicable to the Data, including without limitation any applicable export controls. 4. In any publication resulting from use of the Data, Recipient and Recipient Investigator shall acknowledge Department of Genomic Medicine (“Provider Investigator”) and Provider as the provider of the Data. 5. This Agreement shall be effective as of the Effective Date and shall remain effective until completion of the Research. Either Party may terminate this Agreement with or without cause upon thirty (30) days’ written notice to the other Party. Upon expiration or termination of this Agreement for any reason, Recipient shall destroy all Data received pursuant to this Agreement. 6. Any notice permitted or required as provided for herein shall be in writing and to the contact and address as noted below or as may be provided by either party to the other in writing from time to time. Notice to Provider shall be to: Chief Legal Officer The University of Texas M. D. Anderson Cancer Center 7007 Bertner Ave., 1MC11.3433, Suite 1674 Houston, Texas 77030 Phone: 713-745-6633; Facsimile: 713-745-6029 With a copy to: The University of Texas M. D. Anderson Cancer Center 2 1515 Holcombe Blvd., FCT 8.5025 Office of Research Administration Attn: Executive Director, Research Administration Houston, TX 77030 Phone: 713-792-3672; Facsimile: 713-792-7455 Notice to Recipient shall be to: [insert] 7. In the event Protected Health Information (“PHI”), as defined by the federal Health Insurance Portability and Accountability Act of 1996 (“HIPAA”), as amended, is inadvertently created, accessed by, and/or disclosed to Recipient in connection with this Agreement, Recipient will immediately notify the Provider and will return to Provider or destroy such PHI, in accordance with the Provider’s instructions. Pending return or destruction of any PHI, Recipient shall maintain the confidentiality of all Data (including the PHI) and use appropriate safeguards to prevent access to, use, or disclosure of Data (including the PHI). 8. PROVIDER MAKES NO REPRESENTATION OR WARRANTY CONCERNING THE MATERIAL, INCLUDING WITHOUT LIMITATION, WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OR ANY OTHER WARRANTY, EXPRESS OR IMPLIED. 9. Recipient Investigator and Recipient accept all liability for any use of the Data and for any loss, claim, or damage which may arise from or in connection with this Agreement or the use, handling or storage of the Data and in no event shall Provider or Provider Investigator be liable for any such use, loss, claim or damage. [Insert Recipient Name Here] THE UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER By: By: Name: Name: Title: Title: Date: Date: Read and Understood: Recipient Scientist: Provider Scientist: [Insert Name and Title Here] [Insert Name and Title Here] Date: Date:

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005284766 1620591425712 2.0 GB
EGAF00005284767 1620591425712 12.5 GB
EGAF00005284770 1620591425712 10.7 GB
EGAF00005284771 1620591425712 5.3 GB
EGAF00005284772 1620591425712 1.9 GB
EGAF00005284773 1620591425712 19.0 GB
EGAF00005284776 1620591425712 2.0 GB
EGAF00005284777 1620591425712 20.2 GB
EGAF00005284778 1620591425712 18.7 GB
EGAF00005284779 1620591425712 5.1 GB
EGAF00005284787 1620591484970 2.0 GB
EGAF00005284788 1620591484970 11.8 GB
EGAF00005284789 1620591484970 10.9 GB
EGAF00005284790 1620591484970 5.5 GB
EGAF00005284791 1620591484970 2.0 GB
EGAF00005284792 1620591484970 12.0 GB
EGAF00005284803 1620591484970 10.8 GB
EGAF00005284804 1620591484970 5.5 GB
EGAF00005284807 1620591484970 11.3 GB
EGAF00005284808 1620591484970 5.8 GB
EGAF00005284809 1620591484970 1.9 GB
EGAF00005284810 1620591484970 19.0 GB
EGAF00005284813 1620591484970 11.3 GB
EGAF00005284814 1620591484970 5.4 GB
EGAF00005284817 1620591484970 2.0 GB
EGAF00005284818 1620591484970 12.4 GB
EGAF00005284819 1620591484970 2.0 GB
EGAF00005284820 1620591484970 19.2 GB
EGAF00005284821 1620591484970 18.7 GB
EGAF00005284822 1620591484970 5.2 GB
EGAF00005284825 1620591484970 2.1 GB
EGAF00005284826 1620591484970 12.2 GB
EGAF00005284853 1620591484970 1.9 GB
EGAF00005284854 1620591484970 11.8 GB
EGAF00005284858 1620591484970 10.8 GB
EGAF00005284859 1620591484970 5.4 GB
EGAF00005284863 1620591484970 1.9 GB
EGAF00005284864 1620591484970 11.8 GB
EGAF00005284866 1620591546353 11.6 GB
EGAF00005284867 1620591546353 5.8 GB
EGAF00005284868 1620591546353 2.0 GB
EGAF00005284869 1620591546353 12.2 GB
EGAF00005284870 1620591546353 19.6 GB
EGAF00005284871 1620591546353 4.6 GB
EGAF00005284872 1620591546353 2.0 GB
EGAF00005284873 1620591546353 18.1 GB
EGAF00005284876 1620591546353 11.3 GB
EGAF00005284877 1620591546353 5.7 GB
EGAF00005284880 1620591546353 11.3 GB
EGAF00005284881 1620591546353 5.8 GB
EGAF00005284882 1620591546353 2.0 GB
EGAF00005284883 1620591546353 12.4 GB
EGAF00005284904 1620591546353 2.0 GB
EGAF00005284905 1620591546353 20.7 GB
EGAF00005284906 1620591546353 19.2 GB
EGAF00005284907 1620591546353 5.5 GB
EGAF00005284908 1620591546353 19.5 GB
EGAF00005284909 1620591546353 5.5 GB
EGAF00005284910 1620591546353 11.3 GB
EGAF00005284911 1620591546353 5.7 GB
EGAF00005284912 1620591546353 2.0 GB
EGAF00005284913 1620591546353 20.6 GB
EGAF00005284933 1620591546353 19.2 GB
EGAF00005284934 1620591546353 5.6 GB
EGAF00005284957 1620591610326 2.0 GB
EGAF00005284958 1620591610326 12.3 GB
EGAF00005284959 1620591610326 10.9 GB
EGAF00005284960 1620591610326 5.5 GB
EGAF00005284961 1620591610326 1.9 GB
EGAF00005284962 1620591610325 12.0 GB
EGAF00005284965 1620591610326 10.7 GB
EGAF00005284966 1620591610326 5.4 GB
EGAF00005284967 1620591610326 18.1 GB
EGAF00005284968 1620591610326 5.1 GB
EGAF00005284977 1620591610326 11.3 GB
EGAF00005284978 1620591610326 5.9 GB
EGAF00005284981 1620591610326 2.0 GB
EGAF00005284982 1620591610326 12.5 GB
EGAF00005284991 1620591610325 1.9 GB
EGAF00005284992 1620591610325 12.1 GB
EGAF00005284993 1620591610325 10.8 GB
EGAF00005284994 1620591610325 5.5 GB
EGAF00005285019 1620591610326 1.9 GB
EGAF00005285020 1620591610325 11.9 GB
EGAF00005285021 1620591610326 2.1 GB
EGAF00005285022 1620591610326 12.4 GB
EGAF00005285023 1620591610326 19.2 GB
EGAF00005285024 1620591610326 5.6 GB
EGAF00005285025 1620591610326 11.3 GB
EGAF00005285026 1620591610326 5.8 GB
EGAF00005285029 1620591610326 10.7 GB
EGAF00005285030 1620591670410 5.4 GB
EGAF00005285031 1620591670410 2.1 GB
EGAF00005285032 1620591670410 12.4 GB
EGAF00005285041 1620591670410 2.0 GB
EGAF00005285042 1620591670410 20.5 GB
96 Files (860.8 GB)