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Single cell BCR sequencing

Paired-end fastq files of 22 AML and 2 normal bone marrow samples were generated using 10x Genomics single cell BCR sequencing following manufacturer's protocol (CG000086 User Guide RevG) for chemistry version 1.0 and targeting 10000 cells per sample. Libraries were sequenced using Illumina NovaSeq 6000 using recommended cycling parameters.

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Department of Genomic Medicine Data Access Agreement

DATA ACCESS AGREEMENT This Data Access Agreement (“Agreement”), effective as of the ____ day of _________________, 20__ (“Effective Date”), is by and between The University of Texas M. D. Anderson Cancer Center, an institution of The University of Texas System and an agency of the State of Texas, with an address at 1515 Holcombe Boulevard, Houston, Texas 77030 (“Provider”), and ________________________________ (“Recipient”) on behalf of its investigator _______ (“Recipient Investigator”) (collectively, the “Parties”; each, a “Party”). RECITALS Provider maintains the following de-identified data in the European Genome-phenome Archive (EGA) managed by the European Bioinformatics Institute ________________ (“Data”), and Provider is willing to allow Recipient to access such Data from the EGA for the internal noncommercial research purposes of _______________ (“Purpose”), pursuant to the terms of this Agreement. In consideration of the mutual promises and covenants herein, and for other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the Parties agree as follows: 1. The Data will be used solely for the Research by Recipient Investigator at Recipient, and may not be transferred to any other investigator or to any third party without prior written permission from Provider. The Material may not be used for any purpose other than the Research, including without limitation for any commercial purpose or for research in human subjects (including, without limitation, in diagnostic testing). 2. Neither Recipient nor Recipient Investigator shall disclose Data to any person or party other than the Recipient Investigator hereunder without Provider’s prior written consent. 3. The Data will be used in compliance with all applicable laws, regulations, and guidelines applicable to the Data, including without limitation any applicable export controls. 4. In any publication resulting from use of the Data, Recipient and Recipient Investigator shall acknowledge Department of Genomic Medicine (“Provider Investigator”) and Provider as the provider of the Data. 5. This Agreement shall be effective as of the Effective Date and shall remain effective until completion of the Research. Either Party may terminate this Agreement with or without cause upon thirty (30) days’ written notice to the other Party. Upon expiration or termination of this Agreement for any reason, Recipient shall destroy all Data received pursuant to this Agreement. 6. Any notice permitted or required as provided for herein shall be in writing and to the contact and address as noted below or as may be provided by either party to the other in writing from time to time. Notice to Provider shall be to: Chief Legal Officer The University of Texas M. D. Anderson Cancer Center 7007 Bertner Ave., 1MC11.3433, Suite 1674 Houston, Texas 77030 Phone: 713-745-6633; Facsimile: 713-745-6029 With a copy to: The University of Texas M. D. Anderson Cancer Center 2 1515 Holcombe Blvd., FCT 8.5025 Office of Research Administration Attn: Executive Director, Research Administration Houston, TX 77030 Phone: 713-792-3672; Facsimile: 713-792-7455 Notice to Recipient shall be to: [insert] 7. In the event Protected Health Information (“PHI”), as defined by the federal Health Insurance Portability and Accountability Act of 1996 (“HIPAA”), as amended, is inadvertently created, accessed by, and/or disclosed to Recipient in connection with this Agreement, Recipient will immediately notify the Provider and will return to Provider or destroy such PHI, in accordance with the Provider’s instructions. Pending return or destruction of any PHI, Recipient shall maintain the confidentiality of all Data (including the PHI) and use appropriate safeguards to prevent access to, use, or disclosure of Data (including the PHI). 8. PROVIDER MAKES NO REPRESENTATION OR WARRANTY CONCERNING THE MATERIAL, INCLUDING WITHOUT LIMITATION, WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OR ANY OTHER WARRANTY, EXPRESS OR IMPLIED. 9. Recipient Investigator and Recipient accept all liability for any use of the Data and for any loss, claim, or damage which may arise from or in connection with this Agreement or the use, handling or storage of the Data and in no event shall Provider or Provider Investigator be liable for any such use, loss, claim or damage. [Insert Recipient Name Here] THE UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER By: By: Name: Name: Title: Title: Date: Date: Read and Understood: Recipient Scientist: Provider Scientist: [Insert Name and Title Here] [Insert Name and Title Here] Date: Date:

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005284761 1620591425712 1.1 GB
EGAF00005284762 1620591425712 2.5 GB
EGAF00005284763 1620591425712 1.2 GB
EGAF00005284764 1620591425712 2.9 GB
EGAF00005284768 1620591425712 1.7 GB
EGAF00005284769 1620591425712 3.9 GB
EGAF00005284783 1620591425712 1.4 GB
EGAF00005284784 1620591484970 3.3 GB
EGAF00005284785 1620591484970 1.4 GB
EGAF00005284786 1620591484970 3.3 GB
EGAF00005284827 1620591484970 1.4 GB
EGAF00005284828 1620591484970 3.3 GB
EGAF00005284829 1620591484970 1.3 GB
EGAF00005284830 1620591484970 3.2 GB
EGAF00005284833 1620591484970 1.7 GB
EGAF00005284834 1620591484970 3.9 GB
EGAF00005284851 1620591484970 1.7 GB
EGAF00005284852 1620591484970 4.0 GB
EGAF00005284891 1620591546353 1.4 GB
EGAF00005284892 1620591546353 3.0 GB
EGAF00005284898 1620591546353 1.3 GB
EGAF00005284899 1620591546353 3.2 GB
EGAF00005284914 1620591546353 1.5 GB
EGAF00005284915 1620591546353 3.7 GB
EGAF00005284916 1620591546353 1.4 GB
EGAF00005284917 1620591546353 3.5 GB
EGAF00005284920 1620591546353 1.4 GB
EGAF00005284921 1620591546353 3.6 GB
EGAF00005284922 1620591546353 1.4 GB
EGAF00005284923 1620591546353 3.3 GB
EGAF00005284942 1620591546353 1.5 GB
EGAF00005284943 1620591546353 3.6 GB
EGAF00005284946 1620591546353 1.5 GB
EGAF00005284947 1620591546353 3.5 GB
EGAF00005284948 1620591610326 1.5 GB
EGAF00005284949 1620591610326 3.3 GB
EGAF00005284969 1620591610326 1.9 GB
EGAF00005284970 1620591610326 4.4 GB
EGAF00005284973 1620591610326 1.7 GB
EGAF00005284974 1620591610326 4.1 GB
EGAF00005284999 1620591610325 1.5 GB
EGAF00005285000 1620591610325 3.4 GB
EGAF00005285001 1620591610325 1.4 GB
EGAF00005285002 1620591610325 3.4 GB
EGAF00005285005 1620591610326 1.4 GB
EGAF00005285006 1620591610326 3.4 GB
EGAF00005285009 1620591610326 1.4 GB
EGAF00005285010 1620591610326 3.5 GB
48 Files (118.2 GB)