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Profiling of H3K27ac landscape in five immune cell types from rheumatoid arthritis patients and healthy controls

We collected peripheral blood mononuclear cells (PBMC) from 6 RA patients and 4 healthy controls, as well as synovial fluid (SF) from the same RA patients. We then sorted B cells, CD4+ and CD8+ T cells, regulatory T cells and monocytes using flow cytometry and profiled regions marked with H3K27ac using CUT&Tag.

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The DAC of Department of clinical immunology, Xijing hospital has been established to provide oversight and guidance on data access issues. The Committee monitors the progress of all data requests and also reviews any requests for access that raise particular issues.

Ownership and Intellectual Property Department of clinical immunology,Xijing hospital is the only owner of the data. We have a rigorous review process for researchers who want to use the data. Our data is restricted to open access. Researchers who want to use the data must submit application for use to the DAC of Department of clinical immunology. Data only shared with bona fide researchers Requesters should be employees of a recognised academic institution, health service organisation or charitable research organisation with experience in medical research. Requestors should be able to demonstrate, through their peer reviewed publications in the area of interest, their ability to carry out the proposed study. Their organisation should have formal policies and procedures to comply with any legal, ethical or data protection constraints and to ensure that the dataset is stored securely and used responsibly. Independent Oversight of Access An Independent Access Committee has been established to provide oversight and guidance on data access issues. The Committee will monitor the progress of all data requests. Protecting the Identity of Participants Safeguards will be maintained to ensure the anonymity and confidentiality of participants’ data. Researchers will enter a legal agreement not to make any attempt to identify participants, and the data provided to researchers will not contain any personally identifiable variables.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005068218 1615327676934 202.5 MB
EGAF00005068219 1615327819308 211.3 MB
EGAF00005068220 1615327676934 140.0 MB
EGAF00005068221 1615327676934 144.2 MB
EGAF00005068222 1615328417712 244.6 MB
EGAF00005068223 1615327676934 249.1 MB
EGAF00005068224 1615328047935 325.4 MB
EGAF00005068225 1615328417712 340.6 MB
EGAF00005068226 1615327676934 137.9 MB
EGAF00005068227 1615327756101 147.5 MB
EGAF00005068228 1615327676934 113.9 MB
EGAF00005068229 1615327676934 122.5 MB
EGAF00005068230 1615327819308 189.1 MB
EGAF00005068231 1615327756101 196.0 MB
EGAF00005068232 1615327756101 293.1 MB
EGAF00005068233 1615328047935 311.8 MB
EGAF00005068234 1615328113517 224.8 MB
EGAF00005068235 1615327819308 233.9 MB
EGAF00005068236 1615328173711 427.8 MB
EGAF00005068237 1615328047935 449.7 MB
EGAF00005068238 1615328047935 348.8 MB
EGAF00005068239 1615328113517 356.4 MB
EGAF00005068240 1615328113517 285.2 MB
EGAF00005068241 1615328047935 302.0 MB
EGAF00005068242 1615328583344 315.8 MB
EGAF00005068243 1615329005246 324.8 MB
EGAF00005068244 1615328173711 193.2 MB
EGAF00005068245 1615328047935 197.4 MB
EGAF00005068246 1615327998439 159.1 MB
EGAF00005068247 1615328417712 167.0 MB
EGAF00005068248 1615328583344 289.9 MB
EGAF00005068249 1615328583344 304.5 MB
EGAF00005068250 1615328471522 337.7 MB
EGAF00005068251 1615328540855 355.4 MB
EGAF00005068252 1615328113517 97.2 MB
EGAF00005068253 1615328285077 101.9 MB
EGAF00005068254 1615328343847 225.6 MB
EGAF00005068255 1615328471522 235.7 MB
EGAF00005068256 1615328471522 331.1 MB
EGAF00005068257 1615328833257 339.4 MB
EGAF00005068258 1615328766828 578.4 MB
EGAF00005068259 1615328766828 593.5 MB
EGAF00005068260 1615328888405 423.4 MB
EGAF00005068261 1615328943271 441.5 MB
EGAF00005068262 1615328417712 232.7 MB
EGAF00005068263 1615328471522 236.8 MB
EGAF00005068264 1615328343847 212.0 MB
EGAF00005068265 1615328540855 218.1 MB
EGAF00005068266 1615328343847 204.9 MB
EGAF00005068267 1615328343847 209.9 MB
EGAF00005068268 1615328833257 137.7 MB
EGAF00005068269 1615328888405 138.5 MB
EGAF00005068270 1615328766828 337.3 MB
EGAF00005068271 1615328540855 348.1 MB
EGAF00005068272 1615328223840 158.4 MB
EGAF00005068273 1615328285077 167.7 MB
EGAF00005068274 1615328223840 159.1 MB
EGAF00005068275 1615328223840 164.1 MB
EGAF00005068276 1615328343847 166.0 MB
EGAF00005068277 1615328285077 172.2 MB
EGAF00005068278 1615328833257 365.1 MB
EGAF00005068279 1615328833257 378.0 MB
EGAF00005068280 1615328583344 414.1 MB
EGAF00005068281 1615329123920 434.8 MB
EGAF00005068282 1615328703387 447.2 MB
EGAF00005068283 1615328833257 463.8 MB
EGAF00005068284 1615328583344 396.3 MB
EGAF00005068285 1615328583344 405.0 MB
EGAF00005068286 1615328471522 172.8 MB
EGAF00005068287 1615328471522 213.1 MB
EGAF00005068288 1615328417712 162.5 MB
EGAF00005068289 1615328417712 169.4 MB
EGAF00005068290 1615328173711 149.8 MB
EGAF00005068291 1615328173711 152.0 MB
EGAF00005068292 1615328285077 187.1 MB
EGAF00005068293 1615328471522 196.7 MB
EGAF00005068294 1615328833257 364.9 MB
EGAF00005068295 1615328648261 379.6 MB
EGAF00005068296 1615328583344 292.0 MB
EGAF00005068297 1615328471522 302.9 MB
EGAF00005068298 1615328833257 354.4 MB
EGAF00005068299 1615328540855 346.9 MB
EGAF00005068300 1615328648261 414.8 MB
EGAF00005068301 1615328703387 418.7 MB
EGAF00005068302 1615328173711 150.5 MB
EGAF00005068303 1615328343847 158.3 MB
EGAF00005068304 1615328113517 99.0 MB
EGAF00005068305 1615328173711 104.7 MB
EGAF00005068306 1615328766828 333.9 MB
EGAF00005068307 1615328540855 352.2 MB
EGAF00005068308 1615328113517 134.2 MB
EGAF00005068309 1615328833257 141.2 MB
EGAF00005068310 1615328417712 185.3 MB
EGAF00005068311 1615328343847 194.4 MB
EGAF00005068312 1615328540855 353.8 MB
EGAF00005068313 1615328540855 374.3 MB
EGAF00005068314 1615328648261 360.6 MB
EGAF00005068315 1615329005246 362.0 MB
EGAF00005068316 1615328766828 469.9 MB
EGAF00005068317 1615328766828 491.2 MB
EGAF00005068318 1615328173711 155.1 MB
EGAF00005068319 1615328173711 146.2 MB
EGAF00005068320 1615328343847 203.4 MB
EGAF00005068321 1615328471522 213.8 MB
EGAF00005068322 1615328703387 419.0 MB
EGAF00005068323 1615328943271 429.0 MB
EGAF00005068324 1615328343847 158.5 MB
EGAF00005068325 1615328223840 163.6 MB
EGAF00005068326 1615328471522 310.7 MB
EGAF00005068327 1615328471522 328.1 MB
EGAF00005068328 1615328173711 156.4 MB
EGAF00005068329 1615328343847 161.9 MB
EGAF00005068330 1615328173711 89.6 MB
EGAF00005068331 1615328285077 93.8 MB
EGAF00005068332 1615328583344 413.9 MB
EGAF00005068333 1615328888405 432.3 MB
EGAF00005068334 1615328417712 280.6 MB
EGAF00005068335 1615328471522 291.6 MB
118 Files (31.6 GB)