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Profiling of H3K27ac landscape in five immune cell types from rheumatoid arthritis patients and healthy controls

We collected peripheral blood mononuclear cells (PBMC) from 6 RA patients and 4 healthy controls, as well as synovial fluid (SF) from the same RA patients. We then sorted B cells, CD4+ and CD8+ T cells, regulatory T cells and monocytes using flow cytometry and profiled regions marked with H3K27ac using CUT&Tag.

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The DAC of Department of clinical immunology, Xijing hospital has been established to provide oversight and guidance on data access issues. The Committee monitors the progress of all data requests and also reviews any requests for access that raise particular issues.

Ownership and Intellectual Property Department of clinical immunology,Xijing hospital is the only owner of the data. We have a rigorous review process for researchers who want to use the data. Our data is restricted to open access. Researchers who want to use the data must submit application for use to the DAC of Department of clinical immunology. Data only shared with bona fide researchers Requesters should be employees of a recognised academic institution, health service organisation or charitable research organisation with experience in medical research. Requestors should be able to demonstrate, through their peer reviewed publications in the area of interest, their ability to carry out the proposed study. Their organisation should have formal policies and procedures to comply with any legal, ethical or data protection constraints and to ensure that the dataset is stored securely and used responsibly. Independent Oversight of Access An Independent Access Committee has been established to provide oversight and guidance on data access issues. The Committee will monitor the progress of all data requests. Protecting the Identity of Participants Safeguards will be maintained to ensure the anonymity and confidentiality of participants’ data. Researchers will enter a legal agreement not to make any attempt to identify participants, and the data provided to researchers will not contain any personally identifiable variables.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001005085 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00005068218 fq.gz 202.5 MB
EGAF00005068219 fq.gz 211.3 MB
EGAF00005068220 fq.gz 140.0 MB
EGAF00005068221 fq.gz 144.2 MB
EGAF00005068222 fq.gz 244.6 MB
EGAF00005068223 fq.gz 249.1 MB
EGAF00005068224 fq.gz 325.4 MB
EGAF00005068225 fq.gz 340.6 MB
EGAF00005068226 fq.gz 137.9 MB
EGAF00005068227 fq.gz 147.5 MB
EGAF00005068228 fq.gz 113.9 MB
EGAF00005068229 fq.gz 122.5 MB
EGAF00005068230 fq.gz 189.1 MB
EGAF00005068231 fq.gz 196.0 MB
EGAF00005068232 fq.gz 293.1 MB
EGAF00005068233 fq.gz 311.8 MB
EGAF00005068234 fq.gz 224.8 MB
EGAF00005068235 fq.gz 233.9 MB
EGAF00005068236 fq.gz 427.8 MB
EGAF00005068237 fq.gz 449.7 MB
EGAF00005068238 fq.gz 348.8 MB
EGAF00005068239 fq.gz 356.4 MB
EGAF00005068240 fq.gz 285.2 MB
EGAF00005068241 fq.gz 302.0 MB
EGAF00005068242 fq.gz 315.8 MB
EGAF00005068243 fq.gz 324.8 MB
EGAF00005068244 fq.gz 193.2 MB
EGAF00005068245 fq.gz 197.4 MB
EGAF00005068246 fq.gz 159.1 MB
EGAF00005068247 fq.gz 167.0 MB
EGAF00005068248 fq.gz 289.9 MB
EGAF00005068249 fq.gz 304.5 MB
EGAF00005068250 fq.gz 337.7 MB
EGAF00005068251 fq.gz 355.4 MB
EGAF00005068252 fq.gz 97.2 MB
EGAF00005068253 fq.gz 101.9 MB
EGAF00005068254 fq.gz 225.6 MB
EGAF00005068255 fq.gz 235.7 MB
EGAF00005068256 fq.gz 331.1 MB
EGAF00005068257 fq.gz 339.4 MB
EGAF00005068258 fq.gz 578.4 MB
EGAF00005068259 fq.gz 593.5 MB
EGAF00005068260 fq.gz 423.4 MB
EGAF00005068261 fq.gz 441.5 MB
EGAF00005068262 fq.gz 232.7 MB
EGAF00005068263 fq.gz 236.8 MB
EGAF00005068264 fq.gz 212.0 MB
EGAF00005068265 fq.gz 218.1 MB
EGAF00005068266 fq.gz 204.9 MB
EGAF00005068267 fq.gz 209.9 MB
EGAF00005068268 fq.gz 137.7 MB
EGAF00005068269 fq.gz 138.5 MB
EGAF00005068270 fq.gz 337.3 MB
EGAF00005068271 fq.gz 348.1 MB
EGAF00005068272 fq.gz 158.4 MB
EGAF00005068273 fq.gz 167.7 MB
EGAF00005068274 fq.gz 159.1 MB
EGAF00005068275 fq.gz 164.1 MB
EGAF00005068276 fq.gz 166.0 MB
EGAF00005068277 fq.gz 172.2 MB
EGAF00005068278 fq.gz 365.1 MB
EGAF00005068279 fq.gz 378.0 MB
EGAF00005068280 fq.gz 414.1 MB
EGAF00005068281 fq.gz 434.8 MB
EGAF00005068282 fq.gz 447.2 MB
EGAF00005068283 fq.gz 463.8 MB
EGAF00005068284 fq.gz 396.3 MB
EGAF00005068285 fq.gz 405.0 MB
EGAF00005068286 fq.gz 172.8 MB
EGAF00005068287 fq.gz 213.1 MB
EGAF00005068288 fq.gz 162.5 MB
EGAF00005068289 fq.gz 169.4 MB
EGAF00005068290 fq.gz 149.8 MB
EGAF00005068291 fq.gz 152.0 MB
EGAF00005068292 fq.gz 187.1 MB
EGAF00005068293 fq.gz 196.7 MB
EGAF00005068294 fq.gz 364.9 MB
EGAF00005068295 fq.gz 379.6 MB
EGAF00005068296 fq.gz 292.0 MB
EGAF00005068297 fq.gz 302.9 MB
EGAF00005068298 fq.gz 354.4 MB
EGAF00005068299 fq.gz 346.9 MB
EGAF00005068300 fq.gz 414.8 MB
EGAF00005068301 fq.gz 418.7 MB
EGAF00005068302 fq.gz 150.5 MB
EGAF00005068303 fq.gz 158.3 MB
EGAF00005068304 fq.gz 99.0 MB
EGAF00005068305 fq.gz 104.7 MB
EGAF00005068306 fq.gz 333.9 MB
EGAF00005068307 fq.gz 352.2 MB
EGAF00005068308 fq.gz 134.2 MB
EGAF00005068309 fq.gz 141.2 MB
EGAF00005068310 fq.gz 185.3 MB
EGAF00005068311 fq.gz 194.4 MB
EGAF00005068312 fq.gz 353.8 MB
EGAF00005068313 fq.gz 374.3 MB
EGAF00005068314 fq.gz 360.6 MB
EGAF00005068315 fq.gz 362.0 MB
EGAF00005068316 fq.gz 469.9 MB
EGAF00005068317 fq.gz 491.2 MB
EGAF00005068318 fq.gz 155.1 MB
EGAF00005068319 fq.gz 146.2 MB
EGAF00005068320 fq.gz 203.4 MB
EGAF00005068321 fq.gz 213.8 MB
EGAF00005068322 fq.gz 419.0 MB
EGAF00005068323 fq.gz 429.0 MB
EGAF00005068324 fq.gz 158.5 MB
EGAF00005068325 fq.gz 163.6 MB
EGAF00005068326 fq.gz 310.7 MB
EGAF00005068327 fq.gz 328.1 MB
EGAF00005068328 fq.gz 156.4 MB
EGAF00005068329 fq.gz 161.9 MB
EGAF00005068330 fq.gz 89.6 MB
EGAF00005068331 fq.gz 93.8 MB
EGAF00005068332 fq.gz 413.9 MB
EGAF00005068333 fq.gz 432.3 MB
EGAF00005068334 fq.gz 280.6 MB
EGAF00005068335 fq.gz 291.6 MB
118 Files (31.6 GB)