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MutWP5: CRUK Mutographs of Cancer: Lung: PD43291_Novaseq (Exome) (2021-02-02)

Sequencing of LCM-derived microbiopsies from explanted lung from COPD patient. Goal to assess the mutational burden, spectrum, and clonal dynamics within the tissue. Deep sampling throughout multiple regions of the lung will determine whether there are differences in smoking-related mutaiton burden in different portions of the lung. Whole-genome sequencing will be conducted on samples identified as promising from the initial targeted data. Results from this poriton of the study will be compared to other individuals with smoking-related diseases (COPD, pulmonary fibrosis, lung cancer), and normal, non-smoking lungs. . This dataset contains all the data available for this study on 2021-02-02.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00004458590 cram 5.2 GB
EGAF00004458591 cram 6.2 GB
EGAF00004458592 cram 3.8 GB
EGAF00004458593 cram 4.5 GB
EGAF00004458594 cram 5.3 GB
EGAF00004458595 cram 6.9 GB
EGAF00004458596 cram 5.3 GB
EGAF00004458597 cram 4.8 GB
EGAF00004458598 cram 3.9 GB
EGAF00004458599 cram 4.9 GB
EGAF00004458600 cram 4.2 GB
EGAF00004458601 cram 3.6 GB
EGAF00004458602 cram 5.2 GB
EGAF00004458603 cram 5.9 GB
EGAF00004458604 cram 4.4 GB
EGAF00004458605 cram 4.5 GB
EGAF00004458606 cram 4.9 GB
EGAF00004458607 cram 4.9 GB
EGAF00004458608 cram 3.9 GB
EGAF00004458609 cram 4.7 GB
20 Files (97.0 GB)