MutWP5: CRUK Mutographs of Cancer: Lung: PD37920 (Targeted) (2021-02-02)
Sequencing of LCM-derived microbiopsies from explanted lung from COPD patient. Goal to assess the mutational burden, spectrum, and clonal dynamics within the tissue. Deep sampling throughout multiple regions of the lung will determine whether there are differences in smoking-related mutation burden in different portions of the lung. Targeted sequencing will be conducted on samples to identify drivers of interest and clonality of the samples, well-performing samples will be sent for subsequent whole-genome sequencing. Results from this portion of the study will be compared to other individuals with smoking-related diseases (COPD, pulmonary fibrosis, lung cancer), and normal, non-smoking lungs. . This dataset contains all the data available for this study on 2021-02-02.
- 30 samples
- DAC: EGAC00001000000
- Technologies: HiSeq X Ten, Illumina HiSeq 4000
- PUB DUO:0000019 (version: 2021-02-23)publication requiredThis data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community.
- US DUO:0000026 (version: 2021-02-23)user specific restrictionThis data use modifier indicates that use is limited to use by approved users.
- IS DUO:0000028 (version: 2021-02-23)institution specific restrictionThis data use modifier indicates that use is limited to use within an approved institution.
- GRU DUO:0000042 (version: 2021-02-23)general research useThis data use permission indicates that use is allowed for general research use for any research purpose.
Wellcome Trust Sanger Institute Cancer Genome Group Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| Cancer Genomics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00002554561 | cram | 362.1 MB | ||
| EGAF00002554562 | cram | 397.8 MB | ||
| EGAF00002554563 | cram | 352.6 MB | ||
| EGAF00002554564 | cram | 416.0 MB | ||
| EGAF00002554565 | cram | 369.3 MB | ||
| EGAF00002554566 | cram | 360.8 MB | ||
| EGAF00002554567 | cram | 384.6 MB | ||
| EGAF00002554568 | cram | 367.2 MB | ||
| EGAF00002554569 | cram | 427.1 MB | ||
| EGAF00002554570 | cram | 533.6 MB | ||
| EGAF00002554571 | cram | 398.9 MB | ||
| EGAF00002554572 | cram | 373.9 MB | ||
| EGAF00002554573 | cram | 402.7 MB | ||
| EGAF00002554574 | cram | 464.2 MB | ||
| EGAF00002554575 | cram | 378.0 MB | ||
| EGAF00002554576 | cram | 393.5 MB | ||
| EGAF00002554577 | cram | 456.5 MB | ||
| EGAF00002554578 | cram | 367.3 MB | ||
| EGAF00002554579 | cram | 408.5 MB | ||
| EGAF00002554580 | cram | 433.4 MB | ||
| EGAF00002554581 | cram | 396.6 MB | ||
| EGAF00002554582 | cram | 427.7 MB | ||
| EGAF00002554583 | cram | 409.3 MB | ||
| EGAF00002554584 | cram | 426.7 MB | ||
| EGAF00002883976 | cram | 6.2 GB | ||
| EGAF00002883977 | cram | 5.8 GB | ||
| EGAF00002883978 | cram | 6.0 GB | ||
| EGAF00002883979 | cram | 6.3 GB | ||
| EGAF00002883980 | cram | 5.8 GB | ||
| EGAF00002883981 | cram | 6.2 GB | ||
| 30 Files (46.0 GB) | ||||