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Fine-mapping clustered GWAS hits enhances the identification of disease risk and protective genetic variants

This dataset contains: 1) Raw FASTQ and BAM files for short reads. Here, DNA libraries were prepared using Nextera Rapid Capture Custom Enrichment kit (Illumina) and paired-end sequenced on a HiSeq2500 (Illumina). 2) Raw FASTQ and BAM files for long reads. Here, DNA libraries were prepared using 1D DNA ligation Sequencing Kit (SQK-LSK109, Oxford Nanopore) and single-end sequenced on a MinION device (Oxford Nanopore).

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Data Access Policy for short and long-read sequencing results obtained for 86 Brugada syndrome samples.

1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorized Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Guidelines on FAIR Data Management in Horizon 2020 (https://ec.europa.eu/research/participants/data/ref/h2020/grants_manual/hi/oa_pilot/h2020-hi-oa-data-mgt_en.pdf) in https://ec.europa.eu/research/participants/docs/h2020-funding-guide/cross-cutting-issues/open-access-data-management/open-access_en.htm and the Toronto Statement (https://www.nature.com/articles/461168a). This includes but is not limited to recognizing the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 9. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.ott.nih.gov/sites/default/files/documents/pdfs/70fr18413.pdf) conformity with the Organization for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf). 10. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004927 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00004961713 fastq.gz 315.1 MB
EGAF00004961714 fastq.gz 310.2 MB
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EGAF00004961716 fastq.gz 687.9 MB
EGAF00004961717 bam 363.9 MB
EGAF00004961718 bam 335.5 MB
EGAF00004961719 fastq.gz 293.1 MB
EGAF00004961720 fastq.gz 276.2 MB
EGAF00004961721 fastq.gz 323.0 MB
EGAF00004961722 fastq.gz 310.4 MB
EGAF00004961723 fastq.gz 407.6 MB
EGAF00004961724 fastq.gz 428.7 MB
EGAF00004961725 fastq.gz 759.1 MB
EGAF00004961726 fastq.gz 780.7 MB
EGAF00004961727 bam 342.4 MB
EGAF00004961728 fastq.gz 901.0 MB
EGAF00004961729 fastq.gz 928.3 MB
EGAF00004961730 fastq.gz 266.4 MB
EGAF00004961731 fastq.gz 242.3 MB
EGAF00004961732 bam 762.7 MB
EGAF00004961733 bam 291.1 MB
EGAF00004961734 fastq.gz 357.6 MB
EGAF00004961735 fastq.gz 338.5 MB
EGAF00004961736 bam 451.3 MB
EGAF00004961737 bam 699.8 MB
EGAF00004961738 bam 353.7 MB
EGAF00004961739 fastq.gz 839.9 MB
EGAF00004961740 fastq.gz 870.5 MB
EGAF00004961741 fastq.gz 345.6 MB
EGAF00004961742 fastq.gz 336.3 MB
EGAF00004961743 fastq.gz 330.3 MB
EGAF00004961744 fastq.gz 311.1 MB
EGAF00004961745 fastq.gz 273.5 MB
EGAF00004961746 fastq.gz 267.0 MB
EGAF00004961747 fastq.gz 862.6 MB
EGAF00004961748 fastq.gz 853.8 MB
EGAF00004961749 bam 332.5 MB
EGAF00004961750 fastq.gz 352.6 MB
EGAF00004961751 fastq.gz 381.8 MB
EGAF00004961754 bam 817.5 MB
EGAF00004961755 fastq.gz 713.5 MB
EGAF00004961756 fastq.gz 755.4 MB
EGAF00004961757 fastq.gz 706.3 MB
EGAF00004961758 fastq.gz 728.1 MB
EGAF00004961759 bam 345.1 MB
EGAF00004961760 fastq.gz 324.7 MB
EGAF00004961761 fastq.gz 357.4 MB
EGAF00004961762 bam 737.5 MB
EGAF00004961763 fastq.gz 297.2 MB
EGAF00004961764 fastq.gz 276.3 MB
EGAF00004961765 fastq.gz 320.6 MB
EGAF00004961766 fastq.gz 334.5 MB
EGAF00004961767 bam 316.6 MB
EGAF00004961768 fastq.gz 352.6 MB
EGAF00004961769 fastq.gz 344.8 MB
EGAF00004961770 fastq.gz 284.9 MB
EGAF00004961771 fastq.gz 273.2 MB
EGAF00004961772 bam 377.3 MB
EGAF00004961773 bam 333.4 MB
EGAF00004961774 fastq.gz 521.5 MB
EGAF00004961775 fastq.gz 534.2 MB
EGAF00004961776 bam 431.9 MB
EGAF00004961777 fastq.gz 231.0 MB
EGAF00004961778 fastq.gz 216.9 MB
EGAF00004961779 bam 388.0 MB
EGAF00004961780 fastq.gz 273.5 MB
EGAF00004961781 fastq.gz 267.0 MB
EGAF00004961782 fastq.gz 278.5 MB
EGAF00004961783 fastq.gz 271.4 MB
EGAF00004961786 fastq.gz 348.8 MB
EGAF00004961787 fastq.gz 344.0 MB
EGAF00004961800 fastq.gz 278.5 MB
EGAF00004961801 fastq.gz 271.4 MB
EGAF00004961802 fastq.gz 297.5 MB
EGAF00004961803 fastq.gz 303.0 MB
EGAF00004961806 bam 338.5 MB
EGAF00004961807 bam 375.9 MB
EGAF00004961808 fastq.gz 298.4 MB
EGAF00004961809 fastq.gz 292.7 MB
EGAF00004961810 fastq.gz 253.9 MB
EGAF00004961811 fastq.gz 237.7 MB
EGAF00004961812 bam 373.2 MB
EGAF00004961813 fastq.gz 359.1 MB
EGAF00004961814 fastq.gz 341.0 MB
EGAF00004961815 fastq.gz 265.4 MB
EGAF00004961816 fastq.gz 251.9 MB
EGAF00004961817 fastq.gz 293.1 MB
EGAF00004961818 fastq.gz 276.2 MB
EGAF00004961819 bam 371.6 MB
EGAF00004961820 fastq.gz 759.1 MB
EGAF00004961821 fastq.gz 780.7 MB
EGAF00004961828 fastq.gz 792.1 MB
EGAF00004961829 fastq.gz 783.5 MB
EGAF00004961830 bam 868.9 MB
EGAF00004961831 bam 294.4 MB
EGAF00004961834 fastq.gz 312.7 MB
EGAF00004961835 fastq.gz 291.8 MB
EGAF00004961836 bam 337.0 MB
EGAF00004961837 fastq.gz 326.2 MB
EGAF00004961838 fastq.gz 304.8 MB
EGAF00004961839 fastq.gz 279.9 MB
EGAF00004961840 fastq.gz 266.5 MB
EGAF00004961841 fastq.gz 338.4 MB
EGAF00004961842 fastq.gz 343.7 MB
EGAF00004961843 bam 338.5 MB
EGAF00004961844 fastq.gz 374.5 MB
EGAF00004961845 fastq.gz 403.7 MB
EGAF00004961850 bam 384.3 MB
EGAF00004961851 fastq.gz 262.2 MB
EGAF00004961852 fastq.gz 245.4 MB
EGAF00004961853 fastq.gz 346.2 MB
EGAF00004961854 fastq.gz 359.1 MB
EGAF00004961855 fastq.gz 729.9 MB
EGAF00004961856 fastq.gz 743.9 MB
EGAF00004961857 fastq.gz 341.7 MB
EGAF00004961858 fastq.gz 329.3 MB
EGAF00004961859 bam 329.9 MB
EGAF00004961862 fastq.gz 730.3 MB
EGAF00004961863 fastq.gz 770.7 MB
EGAF00004961864 fastq.gz 303.6 MB
EGAF00004961865 fastq.gz 296.0 MB
EGAF00004961866 fastq.gz 299.8 MB
EGAF00004961867 fastq.gz 280.2 MB
EGAF00004961868 bam 335.4 MB
EGAF00004961869 bam 700.7 MB
EGAF00004961870 bam 748.3 MB
EGAF00004961871 bam 406.9 MB
EGAF00004961872 fastq.gz 313.1 MB
EGAF00004961873 fastq.gz 339.5 MB
EGAF00004961874 fastq.gz 826.9 MB
EGAF00004961875 fastq.gz 835.7 MB
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EGAF00004961877 fastq.gz 327.4 MB
EGAF00004961878 fastq.gz 315.4 MB
EGAF00004961879 fastq.gz 273.0 MB
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EGAF00004961882 fastq.gz 792.1 MB
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EGAF00004961889 fastq.gz 363.1 MB
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EGAF00004961892 fastq.gz 337.5 MB
EGAF00004961893 fastq.gz 355.5 MB
EGAF00004961894 fastq.gz 725.9 MB
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EGAF00004961904 bam 319.0 MB
EGAF00004961905 fastq.gz 304.6 MB
EGAF00004961906 fastq.gz 293.7 MB
EGAF00004961907 fastq.gz 643.8 MB
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EGAF00004961911 fastq.gz 346.3 MB
EGAF00004961912 fastq.gz 375.9 MB
EGAF00004961913 fastq.gz 326.2 MB
EGAF00004961914 fastq.gz 304.8 MB
EGAF00004961915 fastq.gz 392.9 MB
EGAF00004961916 fastq.gz 434.2 MB
EGAF00004961917 fastq.gz 803.3 MB
EGAF00004961918 fastq.gz 798.9 MB
EGAF00004961919 fastq.gz 862.6 MB
EGAF00004961920 fastq.gz 853.8 MB
EGAF00004961921 fastq.gz 725.9 MB
EGAF00004961922 fastq.gz 754.1 MB
EGAF00004961923 bam 607.6 MB
EGAF00004961924 fastq.gz 352.6 MB
EGAF00004961925 fastq.gz 344.8 MB
EGAF00004961926 bam 710.4 MB
EGAF00004961927 bam 281.8 MB
EGAF00004961928 fastq.gz 329.1 MB
EGAF00004961929 fastq.gz 309.6 MB
EGAF00004961930 fastq.gz 297.2 MB
EGAF00004961931 fastq.gz 276.3 MB
EGAF00004961932 fastq.gz 304.6 MB
EGAF00004961933 fastq.gz 293.7 MB
EGAF00004961934 fastq.gz 283.9 MB
EGAF00004961935 fastq.gz 273.8 MB
EGAF00004961936 fastq.gz 284.9 MB
EGAF00004961937 fastq.gz 273.2 MB
EGAF00004961938 fastq.gz 692.0 MB
EGAF00004961939 fastq.gz 687.9 MB
EGAF00004961940 fastq.gz 374.5 MB
EGAF00004961941 fastq.gz 403.7 MB
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EGAF00004961945 fastq.gz 329.1 MB
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EGAF00004961950 fastq.gz 222.9 MB
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EGAF00004961969 bam 631.1 MB
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EGAF00004961971 fastq.gz 287.4 MB
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EGAF00004961973 fastq.gz 320.6 MB
EGAF00004961974 fastq.gz 334.5 MB
EGAF00004961975 fastq.gz 345.6 MB
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EGAF00004961977 fastq.gz 295.6 MB
EGAF00004961978 fastq.gz 291.8 MB
EGAF00004961979 bam 376.2 MB
EGAF00004961980 bam 334.9 MB
EGAF00004961981 bam 295.8 MB
EGAF00004961982 fastq.gz 336.9 MB
EGAF00004961983 fastq.gz 353.1 MB
EGAF00004961984 fastq.gz 346.2 MB
EGAF00004961985 fastq.gz 359.1 MB
EGAF00004961986 fastq.gz 265.4 MB
EGAF00004961987 fastq.gz 251.9 MB
EGAF00004961990 bam 323.7 MB
EGAF00004961991 bam 366.8 MB
EGAF00004961992 fastq.gz 267.3 MB
EGAF00004961993 fastq.gz 283.0 MB
EGAF00004961994 bam 377.6 MB
EGAF00004961995 fastq.gz 286.5 MB
EGAF00004961996 fastq.gz 279.6 MB
EGAF00004961997 fastq.gz 337.5 MB
EGAF00004961998 fastq.gz 370.3 MB
EGAF00004961999 fastq.gz 213.6 MB
EGAF00004962000 fastq.gz 194.6 MB
EGAF00004962001 bam 351.2 MB
EGAF00004962002 bam 320.0 MB
EGAF00004962003 bam 316.5 MB
EGAF00004962004 fastq.gz 944.6 MB
EGAF00004962005 fastq.gz 973.6 MB
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EGAF00004962007 bam 314.6 MB
EGAF00004962020 fastq.gz 809.2 MB
EGAF00004962021 fastq.gz 822.5 MB
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EGAF00004962025 fastq.gz 420.1 MB
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EGAF00004962030 fastq.gz 232.3 MB
EGAF00004962031 fastq.gz 901.0 MB
EGAF00004962032 fastq.gz 928.3 MB
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EGAF00004962034 bam 239.8 MB
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EGAF00004962036 fastq.gz 410.2 MB
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555 Files (180.3 GB)