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Chracterising cellur pathways underlying CD3/CD28 activation of human CD4+ cells

We devised an approach to disentangle the TCR and CD28 pathways upon stimulation in naive and memory primary human CD4+ T cells (Tcons) in response to defined stimulatory signals. Sorted Tcons were activated using a titration of anti-CD3 and anti-CD28 in combination as well as individually. As a control we cultured cells in the same conditions but without the stimuli. In total, we defined seven conditions from four individuals for sequencing. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/ .

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001004147 Gene Regulation Study

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00003250657 cram 816.4 MB
EGAF00003250658 cram 877.6 MB
EGAF00003250659 cram 754.0 MB
EGAF00003250660 cram 824.7 MB
EGAF00003250661 cram 655.0 MB
EGAF00003250662 cram 671.2 MB
EGAF00003250663 cram 656.6 MB
EGAF00003250664 cram 908.8 MB
EGAF00003250665 cram 754.5 MB
EGAF00003250666 cram 753.0 MB
EGAF00003250667 cram 683.8 MB
EGAF00003250668 cram 676.4 MB
EGAF00003250669 cram 821.3 MB
EGAF00003250670 cram 744.4 MB
EGAF00003250671 cram 821.4 MB
EGAF00003250672 cram 884.0 MB
EGAF00003250673 cram 755.1 MB
EGAF00003250674 cram 825.5 MB
EGAF00003250675 cram 656.8 MB
EGAF00003250676 cram 672.0 MB
EGAF00003250677 cram 657.0 MB
EGAF00003250678 cram 911.8 MB
EGAF00003250679 cram 756.5 MB
EGAF00003250680 cram 754.9 MB
EGAF00003250681 cram 685.2 MB
EGAF00003250682 cram 677.7 MB
EGAF00003250683 cram 823.9 MB
EGAF00003250684 cram 746.3 MB
EGAF00003250685 cram 817.8 MB
EGAF00003250715 cram 879.1 MB
EGAF00003250716 cram 752.3 MB
EGAF00003250717 cram 822.3 MB
EGAF00003250718 cram 653.3 MB
EGAF00003250719 cram 668.7 MB
EGAF00003250720 cram 654.3 MB
EGAF00003250721 cram 907.2 MB
EGAF00003250722 cram 752.8 MB
EGAF00003250723 cram 751.6 MB
EGAF00003250724 cram 682.7 MB
EGAF00003250725 cram 675.1 MB
EGAF00003250726 cram 821.2 MB
EGAF00003250727 cram 742.7 MB
EGAF00003250728 cram 826.8 MB
EGAF00003250729 cram 888.7 MB
EGAF00003250730 cram 760.3 MB
EGAF00003250731 cram 830.2 MB
EGAF00003250732 cram 660.7 MB
EGAF00003250733 cram 675.8 MB
EGAF00003250734 cram 661.8 MB
EGAF00003250735 cram 917.0 MB
EGAF00003250736 cram 761.1 MB
EGAF00003250737 cram 759.6 MB
EGAF00003250738 cram 690.8 MB
EGAF00003250739 cram 682.7 MB
EGAF00003250740 cram 830.1 MB
EGAF00003250741 cram 751.5 MB
EGAF00003250742 cram 821.8 MB
EGAF00003250743 cram 884.4 MB
EGAF00003250773 cram 758.9 MB
EGAF00003250774 cram 827.5 MB
EGAF00003250775 cram 660.4 MB
EGAF00003250776 cram 673.7 MB
EGAF00003250777 cram 661.5 MB
EGAF00003250778 cram 914.4 MB
EGAF00003250779 cram 761.5 MB
EGAF00003250780 cram 759.2 MB
EGAF00003250781 cram 691.0 MB
EGAF00003250782 cram 682.7 MB
EGAF00003250783 cram 831.2 MB
EGAF00003250784 cram 751.2 MB
EGAF00003250785 cram 464.3 MB
EGAF00003250786 cram 415.5 MB
EGAF00003250787 cram 394.9 MB
EGAF00003250788 cram 402.9 MB
EGAF00003250789 cram 396.8 MB
EGAF00003250790 cram 366.5 MB
EGAF00003250791 cram 400.9 MB
EGAF00003250792 cram 424.2 MB
EGAF00003250793 cram 443.1 MB
EGAF00003250794 cram 438.2 MB
EGAF00003250795 cram 464.2 MB
EGAF00003250796 cram 415.2 MB
EGAF00003250797 cram 394.5 MB
EGAF00003250798 cram 402.5 MB
EGAF00003250799 cram 396.2 MB
EGAF00003250800 cram 366.6 MB
EGAF00003250801 cram 401.2 MB
EGAF00003250831 cram 424.9 MB
EGAF00003250832 cram 443.9 MB
EGAF00003250833 cram 438.3 MB
EGAF00003250834 cram 468.3 MB
EGAF00003250835 cram 418.8 MB
EGAF00003250836 cram 398.7 MB
EGAF00003250837 cram 405.9 MB
EGAF00003250838 cram 399.6 MB
EGAF00003250839 cram 370.2 MB
EGAF00003250840 cram 405.0 MB
EGAF00003250841 cram 427.9 MB
EGAF00003250842 cram 447.1 MB
EGAF00003250843 cram 441.6 MB
EGAF00004838057 cram 410.6 MB
EGAF00004838058 cram 459.4 MB
EGAF00004855657 cram 416.4 MB
EGAF00004855658 cram 369.2 MB
EGAF00004855659 cram 454.1 MB
EGAF00004855660 cram 411.8 MB
EGAF00004855661 cram 430.3 MB
EGAF00004855662 cram 410.8 MB
EGAF00004855663 cram 415.9 MB
EGAF00004855664 cram 369.5 MB
EGAF00004855665 cram 453.8 MB
EGAF00004855666 cram 411.8 MB
EGAF00004855667 cram 430.9 MB
EGAF00004855668 cram 420.4 MB
EGAF00004855669 cram 373.3 MB
EGAF00004855670 cram 415.4 MB
EGAF00004855671 cram 435.3 MB
EGAF00004855672 cram 414.8 MB
118 Files (73.2 GB)