Chracterising cellur pathways underlying CD3/CD28 activation of human CD4+ cells
We devised an approach to disentangle the TCR and CD28 pathways upon stimulation in naive and memory primary human CD4+ T cells (Tcons) in response to defined stimulatory signals. Isolated memory and naïve T cells were activated using anti-CD3, anti-CD28 or both in combination. As a control we cultured cells in the same conditions but without the stimuli. We carried Chipmentation using the H3K27ac antibody on 200,000 cross-linked cells. 1) This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute please see http://www.sanger.ac.uk/datasharing/ .
- 18 samples
- DAC: EGAC00001000205
- Technology: Illumina HiSeq 2500
Wellcome Trust Sanger Institute Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001002599 | Epigenetics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00003250508 | cram | 475.6 MB | ||
| EGAF00003250509 | cram | 540.9 MB | ||
| EGAF00003250510 | cram | 476.4 MB | ||
| EGAF00003250511 | cram | 443.9 MB | ||
| EGAF00003250512 | cram | 456.6 MB | ||
| EGAF00003250542 | cram | 434.3 MB | ||
| EGAF00003250543 | cram | 624.6 MB | ||
| EGAF00003250544 | cram | 529.3 MB | ||
| EGAF00003250545 | cram | 504.6 MB | ||
| EGAF00003250546 | cram | 423.6 MB | ||
| EGAF00003250547 | cram | 504.6 MB | ||
| EGAF00003250548 | cram | 615.9 MB | ||
| EGAF00003250549 | cram | 509.8 MB | ||
| EGAF00003250550 | cram | 529.4 MB | ||
| EGAF00003250551 | cram | 597.2 MB | ||
| EGAF00003250552 | cram | 496.4 MB | ||
| EGAF00003250553 | cram | 527.8 MB | ||
| EGAF00003250554 | cram | 498.9 MB | ||
| EGAF00003250555 | cram | 476.5 MB | ||
| EGAF00003250556 | cram | 542.6 MB | ||
| EGAF00003250557 | cram | 478.1 MB | ||
| EGAF00003250558 | cram | 444.9 MB | ||
| EGAF00003250559 | cram | 458.4 MB | ||
| EGAF00003250560 | cram | 435.4 MB | ||
| EGAF00003250561 | cram | 626.2 MB | ||
| EGAF00003250562 | cram | 530.7 MB | ||
| EGAF00003250563 | cram | 506.3 MB | ||
| EGAF00003250564 | cram | 425.1 MB | ||
| EGAF00003250565 | cram | 505.6 MB | ||
| EGAF00003250566 | cram | 616.7 MB | ||
| EGAF00003250567 | cram | 509.8 MB | ||
| EGAF00003250568 | cram | 528.9 MB | ||
| EGAF00003250569 | cram | 597.5 MB | ||
| EGAF00003250599 | cram | 496.0 MB | ||
| EGAF00003250600 | cram | 527.9 MB | ||
| EGAF00003250601 | cram | 498.5 MB | ||
| EGAF00003250602 | cram | 478.0 MB | ||
| EGAF00003250603 | cram | 543.2 MB | ||
| EGAF00003250604 | cram | 478.9 MB | ||
| EGAF00003250605 | cram | 446.3 MB | ||
| EGAF00003250606 | cram | 459.4 MB | ||
| EGAF00003250607 | cram | 436.6 MB | ||
| EGAF00003250608 | cram | 626.6 MB | ||
| EGAF00003250609 | cram | 530.2 MB | ||
| EGAF00003250610 | cram | 506.8 MB | ||
| EGAF00003250611 | cram | 425.0 MB | ||
| EGAF00003250612 | cram | 506.5 MB | ||
| EGAF00003250613 | cram | 616.3 MB | ||
| EGAF00003250614 | cram | 510.1 MB | ||
| EGAF00003250615 | cram | 529.0 MB | ||
| EGAF00003250616 | cram | 606.1 MB | ||
| EGAF00003250617 | cram | 496.5 MB | ||
| EGAF00003250618 | cram | 529.0 MB | ||
| EGAF00003250619 | cram | 498.9 MB | ||
| 54 Files (27.6 GB) | ||||