Peripheral immunoprofiling of stratifies COVID-19 patients based on disease-specific neutrophil signatures
The SARS-CoV-2 pandemic has led to increasing numbers of COVID-19 patients all over the world. Aetiopathologies range from no symptoms, mild flu-like to severe cases succumbing to respiratory failure. Reports on a dysregulated immune system in the severe cases, showing similarities to cytokine release syndrome, calls for better characterization and understanding of the changes in the immune system as well as their variance across COVID-19 patients in order to be able to design according to host-directed therapies. Here, we profiled blood transcriptomes of 39 COVID-19 patients and 10 control donors. Enriched granulocyte signatures in whole blood samples were verified in granulocyte samples from 49 COVID-19 patients in a second cohort.
- 79 samples
- DAC: EGAC00001001640
- Technology: NextSeq 500
whole blood COVID-19 data access policy
Access to data generated is made available by completing the data access agreement for review by the data access committee and will be granted exclusively to qualified investigators for appropriate use.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001004503 | Other |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00004150656 | fastq.gz | 3.0 GB | ||
| EGAF00004150657 | fastq.gz | 3.2 GB | ||
| EGAF00004150658 | fastq.gz | 3.4 GB | ||
| EGAF00004150659 | fastq.gz | 3.5 GB | ||
| EGAF00004150660 | fastq.gz | 2.4 GB | ||
| EGAF00004150661 | fastq.gz | 2.5 GB | ||
| EGAF00004150662 | fastq.gz | 2.4 GB | ||
| EGAF00004150663 | fastq.gz | 2.6 GB | ||
| EGAF00004150664 | fastq.gz | 2.3 GB | ||
| EGAF00004150665 | fastq.gz | 2.5 GB | ||
| EGAF00004150666 | fastq.gz | 5.3 GB | ||
| EGAF00004150667 | fastq.gz | 5.5 GB | ||
| EGAF00004150668 | fastq.gz | 2.7 GB | ||
| EGAF00004150669 | fastq.gz | 2.8 GB | ||
| EGAF00004150670 | fastq.gz | 2.4 GB | ||
| EGAF00004150671 | fastq.gz | 2.5 GB | ||
| EGAF00004150672 | fastq.gz | 2.8 GB | ||
| EGAF00004150673 | fastq.gz | 3.1 GB | ||
| EGAF00004150674 | fastq.gz | 3.3 GB | ||
| EGAF00004150675 | fastq.gz | 3.6 GB | ||
| EGAF00004150676 | fastq.gz | 3.4 GB | ||
| EGAF00004150677 | fastq.gz | 3.6 GB | ||
| EGAF00004150678 | fastq.gz | 4.9 GB | ||
| EGAF00004150679 | fastq.gz | 5.1 GB | ||
| EGAF00004150680 | fastq.gz | 2.2 GB | ||
| EGAF00004150681 | fastq.gz | 2.2 GB | ||
| EGAF00004150682 | fastq.gz | 2.0 GB | ||
| EGAF00004150683 | fastq.gz | 2.2 GB | ||
| EGAF00004150684 | fastq.gz | 3.3 GB | ||
| EGAF00004150685 | fastq.gz | 3.8 GB | ||
| EGAF00004150686 | fastq.gz | 3.0 GB | ||
| EGAF00004150687 | fastq.gz | 3.1 GB | ||
| EGAF00004150688 | fastq.gz | 2.2 GB | ||
| EGAF00004150689 | fastq.gz | 2.4 GB | ||
| EGAF00004150690 | fastq.gz | 2.5 GB | ||
| EGAF00004150691 | fastq.gz | 2.8 GB | ||
| EGAF00004150692 | fastq.gz | 1.4 GB | ||
| EGAF00004150693 | fastq.gz | 1.6 GB | ||
| EGAF00004150694 | fastq.gz | 3.3 GB | ||
| EGAF00004150695 | fastq.gz | 3.5 GB | ||
| EGAF00004150696 | fastq.gz | 2.5 GB | ||
| EGAF00004150697 | fastq.gz | 2.6 GB | ||
| EGAF00004150698 | fastq.gz | 4.8 GB | ||
| EGAF00004150699 | fastq.gz | 4.9 GB | ||
| EGAF00004150700 | fastq.gz | 3.0 GB | ||
| EGAF00004150701 | fastq.gz | 3.3 GB | ||
| EGAF00004150702 | fastq.gz | 2.0 GB | ||
| EGAF00004150703 | fastq.gz | 2.0 GB | ||
| EGAF00004150704 | fastq.gz | 2.8 GB | ||
| EGAF00004150705 | fastq.gz | 3.0 GB | ||
| EGAF00004150706 | fastq.gz | 2.2 GB | ||
| EGAF00004150707 | fastq.gz | 2.3 GB | ||
| EGAF00004150708 | fastq.gz | 1.2 GB | ||
| EGAF00004150709 | fastq.gz | 1.3 GB | ||
| EGAF00004150710 | fastq.gz | 2.9 GB | ||
| EGAF00004150711 | fastq.gz | 3.1 GB | ||
| EGAF00004150712 | fastq.gz | 9.0 GB | ||
| EGAF00004150713 | fastq.gz | 9.5 GB | ||
| EGAF00004150714 | fastq.gz | 2.7 GB | ||
| EGAF00004150715 | fastq.gz | 2.8 GB | ||
| EGAF00004150716 | fastq.gz | 748.1 MB | ||
| EGAF00004150717 | fastq.gz | 839.5 MB | ||
| EGAF00004150718 | fastq.gz | 2.8 GB | ||
| EGAF00004150719 | fastq.gz | 3.1 GB | ||
| EGAF00004150720 | fastq.gz | 3.3 GB | ||
| EGAF00004150721 | fastq.gz | 3.4 GB | ||
| EGAF00004150722 | fastq.gz | 5.7 GB | ||
| EGAF00004150723 | fastq.gz | 6.1 GB | ||
| EGAF00004150724 | fastq.gz | 3.5 GB | ||
| EGAF00004150725 | fastq.gz | 3.8 GB | ||
| EGAF00004150726 | fastq.gz | 4.2 GB | ||
| EGAF00004150727 | fastq.gz | 4.4 GB | ||
| EGAF00004150728 | fastq.gz | 2.5 GB | ||
| EGAF00004150729 | fastq.gz | 2.5 GB | ||
| EGAF00004150730 | fastq.gz | 2.1 GB | ||
| EGAF00004150731 | fastq.gz | 2.3 GB | ||
| EGAF00004150732 | fastq.gz | 2.5 GB | ||
| EGAF00004150733 | fastq.gz | 2.6 GB | ||
| EGAF00004150734 | fastq.gz | 5.1 GB | ||
| EGAF00004150735 | fastq.gz | 5.6 GB | ||
| EGAF00004150736 | fastq.gz | 5.6 GB | ||
| EGAF00004150737 | fastq.gz | 5.8 GB | ||
| EGAF00004150738 | fastq.gz | 603.6 MB | ||
| EGAF00004150739 | fastq.gz | 659.0 MB | ||
| EGAF00004150740 | fastq.gz | 773.4 MB | ||
| EGAF00004150741 | fastq.gz | 822.4 MB | ||
| EGAF00004150742 | fastq.gz | 566.7 MB | ||
| EGAF00004150743 | fastq.gz | 586.0 MB | ||
| EGAF00004150744 | fastq.gz | 703.0 MB | ||
| EGAF00004150745 | fastq.gz | 725.8 MB | ||
| EGAF00004150746 | fastq.gz | 738.6 MB | ||
| EGAF00004150747 | fastq.gz | 771.0 MB | ||
| EGAF00004150748 | fastq.gz | 593.4 MB | ||
| EGAF00004150749 | fastq.gz | 613.3 MB | ||
| EGAF00004150750 | fastq.gz | 419.7 MB | ||
| EGAF00004150751 | fastq.gz | 425.3 MB | ||
| EGAF00004150752 | fastq.gz | 420.1 MB | ||
| EGAF00004150753 | fastq.gz | 428.9 MB | ||
| EGAF00004150754 | fastq.gz | 1.2 GB | ||
| EGAF00004150755 | fastq.gz | 1.3 GB | ||
| EGAF00004150756 | fastq.gz | 1.2 GB | ||
| EGAF00004150757 | fastq.gz | 1.3 GB | ||
| EGAF00004150758 | fastq.gz | 1.2 GB | ||
| EGAF00004150759 | fastq.gz | 1.3 GB | ||
| EGAF00004150760 | fastq.gz | 1.2 GB | ||
| EGAF00004150761 | fastq.gz | 1.4 GB | ||
| EGAF00004150762 | fastq.gz | 1.0 GB | ||
| EGAF00004150763 | fastq.gz | 1.2 GB | ||
| EGAF00004150764 | fastq.gz | 1.1 GB | ||
| EGAF00004150765 | fastq.gz | 1.2 GB | ||
| EGAF00004150766 | fastq.gz | 1.1 GB | ||
| EGAF00004150767 | fastq.gz | 1.3 GB | ||
| EGAF00004150768 | fastq.gz | 1.0 GB | ||
| EGAF00004150769 | fastq.gz | 1.1 GB | ||
| EGAF00004150770 | fastq.gz | 1.4 GB | ||
| EGAF00004150771 | fastq.gz | 1.6 GB | ||
| EGAF00004150772 | fastq.gz | 1.3 GB | ||
| EGAF00004150773 | fastq.gz | 1.5 GB | ||
| EGAF00004150774 | fastq.gz | 1.3 GB | ||
| EGAF00004150775 | fastq.gz | 1.5 GB | ||
| EGAF00004150776 | fastq.gz | 1.3 GB | ||
| EGAF00004150777 | fastq.gz | 1.5 GB | ||
| EGAF00004150778 | fastq.gz | 1.1 GB | ||
| EGAF00004150779 | fastq.gz | 1.3 GB | ||
| EGAF00004150780 | fastq.gz | 1.2 GB | ||
| EGAF00004150781 | fastq.gz | 1.4 GB | ||
| EGAF00004150782 | fastq.gz | 1.4 GB | ||
| EGAF00004150783 | fastq.gz | 1.6 GB | ||
| EGAF00004150784 | fastq.gz | 1.1 GB | ||
| EGAF00004150785 | fastq.gz | 1.3 GB | ||
| EGAF00004150786 | fastq.gz | 1.5 GB | ||
| EGAF00004150787 | fastq.gz | 1.7 GB | ||
| EGAF00004150788 | fastq.gz | 998.6 MB | ||
| EGAF00004150789 | fastq.gz | 1.1 GB | ||
| EGAF00004150790 | fastq.gz | 1.2 GB | ||
| EGAF00004150791 | fastq.gz | 1.3 GB | ||
| EGAF00004150792 | fastq.gz | 1.0 GB | ||
| EGAF00004150793 | fastq.gz | 1.2 GB | ||
| EGAF00004150794 | fastq.gz | 1.4 GB | ||
| EGAF00004150795 | fastq.gz | 1.5 GB | ||
| EGAF00004150796 | fastq.gz | 1.2 GB | ||
| EGAF00004150797 | fastq.gz | 1.4 GB | ||
| EGAF00004150798 | fastq.gz | 1.3 GB | ||
| EGAF00004150799 | fastq.gz | 1.4 GB | ||
| EGAF00004150800 | fastq.gz | 1.4 GB | ||
| EGAF00004150801 | fastq.gz | 1.5 GB | ||
| EGAF00004150802 | fastq.gz | 1.3 GB | ||
| EGAF00004150803 | fastq.gz | 1.4 GB | ||
| EGAF00004150804 | fastq.gz | 930.7 MB | ||
| EGAF00004150805 | fastq.gz | 1.1 GB | ||
| EGAF00004150806 | fastq.gz | 1.1 GB | ||
| EGAF00004150807 | fastq.gz | 1.2 GB | ||
| EGAF00004150808 | fastq.gz | 1.3 GB | ||
| EGAF00004150809 | fastq.gz | 1.4 GB | ||
| EGAF00004150810 | fastq.gz | 1.3 GB | ||
| EGAF00004150811 | fastq.gz | 1.5 GB | ||
| EGAF00004150812 | fastq.gz | 1.6 GB | ||
| EGAF00004150813 | fastq.gz | 1.8 GB | ||
| 158 Files (354.6 GB) | ||||