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RNA-seq study of longitudinal blood cell samples drawn from children at risk of type 1 diabetes

The appearance of type 1 diabetes (T1D)-associated autoantibodies is the first and only measurable parameter to predict progression toward T1D in genetically susceptible individuals. However, autoantibodies indicate an active autoimmune reaction, wherein the immune tolerance is already broken. Therefore, there is a clear and urgent need for new biomarkers that predict the onset of the autoimmune reaction preceding auto-antibody positivity or reflect progressive b-cell destruction. Here we report the mRNA sequencing-based analysis of 306 samples including fractionated samples of CD4+ and CD8+ T cells as well as CD4, CD8 cell fractions and unfractionated PBMC samples longitudinally collected from seven children who developed beta-cell autoimmunity (case subjects) at a young age and matched control subjects.

Request Access

The policy to access the DIABIMMUNE transcriptomics data

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. DATA OWNER Mikael Knip, University of Helsinki, Helsinki, Finland Riitta Lahesmaa, University of Turku, Turku, Finland USER INSTITUTION (Name and address + business id) Definitions Data Access Committee: DIABIMMUNE Transcriptomics Data Access Committee, consisting of data owners who will make the decisions for granting access to the data, hereafter referred to as “the Committee”. Authorised Personnel: The individuals at the User Institution to whom the Committee, grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: The committee and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to follow the relevant legislation regarding the Data Protection Laws as described in Finnish Laws including the legislation to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project unless obliged to retain the data for archival purposes in conformity with the audit or legal requirements. 12. The User Institution will notify the Committee within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify the Committee prior to any significant changes to the protocol for the Project. 14. The User Institution will notify the Committee as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. The data owners may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for the archival purpose in conformity with the audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than the data owners. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of Finland and shall be subject to the exclusive jurisdiction of the Finnish courts. The arbitration shall be conducted in Turku, Finland, in the English language. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for the data owners Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY APPENDIX I – DATASET DETAILS Dataset reference (EGA Study ID and Dataset Details) Name of the project that created the dataset DIABIMMUNE transcriptomics study. Names of other data producers/collaborators Professor Riitta Lahesmaa, Academy of Finland Professor, Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland Professor Mikael Knip, Children’s Hospital, University of Helsinki, and Helsinki University Hospital, Helsinki, Finland Professor Harri Lähdesmäki, Department of Computer Science, Aalto University School of Science, Espoo, Finland Specific limitations on areas of research Minimum protection measures required. The User Institution should delete the raw data from their computers and servers upon the completion of the study for which the data was granted. File access: Data can be held in unencrypted files on an institutional computer system, with Unix user group read/write access for one or more appropriate groups but not Unix world read/write access behind a secure firewall. Laptops holding these data should have password-protected logins and screen locks (set to lock after 5 min of inactivity). If held on USB keys or other portable hard drives, the data must be encrypted. APPENDIX II – PROJECT DETAILS (to be completed by the Requestor) Details of dataset requested, i.e., EGA Study and Dataset Accession Number A brief abstract of the Project in which the Data will be used (500 words max) All Individuals who the User Institution to be named as registered users Name of Registered User Email Job Title Supervisor* All Individuals that should have an account created at the EGA Name of Registered User Email Job Title APPENDIX III – PUBLICATION POLICY The data producers and collaborators have made the first publication of this dataset and do not consider its deposition into public databases to be the equivalent of such publications. The data producers and collaborators anticipate that the dataset could be useful to other qualified researchers for a variety of purposes. However, some areas of work are subject to a publication moratorium. The publication moratorium covers any publications (including oral communications) that describe the use of the dataset. For research papers, submission for publication should not occur until 06 months after these data were first made available on the relevant hosting database unless the committee has provided written consent to earlier submission. In any publications based on these data, please describe how the data can be accessed, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers (e.g., EGAS00000000029), and acknowledge its use in a form agreed by the User Institution with the committee.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00003211291 fastq.gz 4.0 GB
EGAF00003211292 fastq.gz 4.0 GB
EGAF00003211293 fastq.gz 4.5 GB
EGAF00003211294 fastq.gz 4.5 GB
EGAF00003211295 fastq.gz 2.8 GB
EGAF00003211296 fastq.gz 2.8 GB
EGAF00003211297 fastq.gz 3.3 GB
EGAF00003211298 fastq.gz 3.4 GB
EGAF00003211299 fastq.gz 3.3 GB
EGAF00003211300 fastq.gz 3.3 GB
EGAF00003211301 fastq.gz 3.8 GB
EGAF00003211302 fastq.gz 3.8 GB
EGAF00003211303 fastq.gz 3.0 GB
EGAF00003211304 fastq.gz 3.0 GB
EGAF00003211305 fastq.gz 4.9 GB
EGAF00003211306 fastq.gz 4.9 GB
EGAF00003211307 fastq.gz 3.6 GB
EGAF00003211308 fastq.gz 3.6 GB
EGAF00003211309 fastq.gz 3.6 GB
EGAF00003211310 fastq.gz 3.6 GB
EGAF00003211311 fastq.gz 3.6 GB
EGAF00003211312 fastq.gz 3.6 GB
EGAF00003211313 fastq.gz 3.5 GB
EGAF00003211314 fastq.gz 3.5 GB
EGAF00003211315 fastq.gz 4.6 GB
EGAF00003211316 fastq.gz 4.6 GB
EGAF00003211317 fastq.gz 4.1 GB
EGAF00003211318 fastq.gz 4.1 GB
EGAF00003211319 fastq.gz 4.5 GB
EGAF00003211320 fastq.gz 4.5 GB
EGAF00003211321 fastq.gz 3.4 GB
EGAF00003211322 fastq.gz 3.4 GB
EGAF00003211323 fastq.gz 4.8 GB
EGAF00003211324 fastq.gz 4.8 GB
EGAF00003211325 fastq.gz 3.9 GB
EGAF00003211326 fastq.gz 3.9 GB
EGAF00003211327 fastq.gz 3.3 GB
EGAF00003211328 fastq.gz 3.4 GB
EGAF00003211329 fastq.gz 3.4 GB
EGAF00003211330 fastq.gz 3.4 GB
EGAF00003211331 fastq.gz 4.1 GB
EGAF00003211332 fastq.gz 4.1 GB
EGAF00003211333 fastq.gz 4.1 GB
EGAF00003211334 fastq.gz 4.1 GB
EGAF00003211335 fastq.gz 3.7 GB
EGAF00003211336 fastq.gz 3.7 GB
EGAF00003211337 fastq.gz 5.5 GB
EGAF00003211338 fastq.gz 5.4 GB
EGAF00003211339 fastq.gz 3.4 GB
EGAF00003211340 fastq.gz 3.5 GB
EGAF00003211341 fastq.gz 3.9 GB
EGAF00003211342 fastq.gz 3.9 GB
EGAF00003211343 fastq.gz 4.1 GB
EGAF00003211344 fastq.gz 4.1 GB
EGAF00003211345 fastq.gz 4.1 GB
EGAF00003211346 fastq.gz 4.1 GB
EGAF00003211347 fastq.gz 4.3 GB
EGAF00003211348 fastq.gz 4.3 GB
EGAF00003211349 fastq.gz 3.7 GB
EGAF00003211350 fastq.gz 3.8 GB
EGAF00003211351 fastq.gz 4.3 GB
EGAF00003211352 fastq.gz 4.2 GB
EGAF00003211353 fastq.gz 4.4 GB
EGAF00003211354 fastq.gz 4.4 GB
EGAF00003211355 fastq.gz 3.7 GB
EGAF00003211356 fastq.gz 3.7 GB
EGAF00003211357 fastq.gz 4.0 GB
EGAF00003211358 fastq.gz 4.0 GB
EGAF00003211359 fastq.gz 3.1 GB
EGAF00003211360 fastq.gz 3.2 GB
EGAF00003211361 fastq.gz 3.2 GB
EGAF00003211362 fastq.gz 3.2 GB
EGAF00003211363 fastq.gz 4.2 GB
EGAF00003211364 fastq.gz 4.2 GB
EGAF00003211365 fastq.gz 3.7 GB
EGAF00003211366 fastq.gz 3.6 GB
EGAF00003211367 fastq.gz 3.6 GB
EGAF00003211368 fastq.gz 3.6 GB
EGAF00003211369 fastq.gz 3.3 GB
EGAF00003211370 fastq.gz 3.3 GB
EGAF00003211371 fastq.gz 4.0 GB
EGAF00003211372 fastq.gz 4.0 GB
EGAF00003211373 fastq.gz 3.9 GB
EGAF00003211374 fastq.gz 3.9 GB
EGAF00003211375 fastq.gz 4.4 GB
EGAF00003211376 fastq.gz 4.3 GB
EGAF00003211377 fastq.gz 4.0 GB
EGAF00003211378 fastq.gz 4.0 GB
EGAF00003211379 fastq.gz 3.5 GB
EGAF00003211380 fastq.gz 3.5 GB
EGAF00003211381 fastq.gz 3.3 GB
EGAF00003211382 fastq.gz 3.3 GB
EGAF00003211383 fastq.gz 5.4 GB
EGAF00003211384 fastq.gz 5.4 GB
EGAF00003211385 fastq.gz 3.8 GB
EGAF00003211386 fastq.gz 3.8 GB
EGAF00003211387 fastq.gz 3.4 GB
EGAF00003211388 fastq.gz 3.4 GB
EGAF00003211389 fastq.gz 3.5 GB
EGAF00003211390 fastq.gz 3.5 GB
EGAF00003211391 fastq.gz 3.1 GB
EGAF00003211392 fastq.gz 3.1 GB
EGAF00003211393 fastq.gz 3.2 GB
EGAF00003211394 fastq.gz 3.2 GB
EGAF00003211395 fastq.gz 2.9 GB
EGAF00003211396 fastq.gz 2.9 GB
EGAF00003211397 fastq.gz 3.2 GB
EGAF00003211398 fastq.gz 3.2 GB
EGAF00003211399 fastq.gz 3.2 GB
EGAF00003211400 fastq.gz 3.2 GB
EGAF00003211401 fastq.gz 4.7 GB
EGAF00003211402 fastq.gz 4.7 GB
EGAF00003211403 fastq.gz 3.3 GB
EGAF00003211404 fastq.gz 3.3 GB
EGAF00003211405 fastq.gz 3.9 GB
EGAF00003211406 fastq.gz 3.9 GB
EGAF00003211407 fastq.gz 4.5 GB
EGAF00003211408 fastq.gz 4.5 GB
EGAF00003211409 fastq.gz 3.2 GB
EGAF00003211410 fastq.gz 3.3 GB
EGAF00003211411 fastq.gz 4.3 GB
EGAF00003211412 fastq.gz 4.3 GB
EGAF00003211413 fastq.gz 4.1 GB
EGAF00003211414 fastq.gz 4.1 GB
EGAF00003211415 fastq.gz 4.0 GB
EGAF00003211416 fastq.gz 4.0 GB
EGAF00003211417 fastq.gz 3.9 GB
EGAF00003211418 fastq.gz 3.9 GB
EGAF00003211419 fastq.gz 3.9 GB
EGAF00003211420 fastq.gz 3.9 GB
EGAF00003211421 fastq.gz 4.4 GB
EGAF00003211422 fastq.gz 4.4 GB
EGAF00003211423 fastq.gz 4.6 GB
EGAF00003211424 fastq.gz 4.6 GB
EGAF00003211425 fastq.gz 3.7 GB
EGAF00003211426 fastq.gz 3.7 GB
EGAF00003211427 fastq.gz 3.5 GB
EGAF00003211428 fastq.gz 3.5 GB
EGAF00003211429 fastq.gz 3.3 GB
EGAF00003211430 fastq.gz 3.3 GB
EGAF00003211431 fastq.gz 3.5 GB
EGAF00003211432 fastq.gz 3.5 GB
EGAF00003211433 fastq.gz 4.0 GB
EGAF00003211434 fastq.gz 4.0 GB
EGAF00003211435 fastq.gz 4.1 GB
EGAF00003211436 fastq.gz 4.1 GB
EGAF00003211437 fastq.gz 4.0 GB
EGAF00003211438 fastq.gz 4.0 GB
EGAF00003211439 fastq.gz 4.2 GB
EGAF00003211440 fastq.gz 4.2 GB
EGAF00003211441 fastq.gz 4.4 GB
EGAF00003211442 fastq.gz 4.4 GB
EGAF00003211443 fastq.gz 3.6 GB
EGAF00003211444 fastq.gz 3.7 GB
EGAF00003211445 fastq.gz 3.5 GB
EGAF00003211446 fastq.gz 3.5 GB
EGAF00003211447 fastq.gz 3.6 GB
EGAF00003211448 fastq.gz 3.6 GB
EGAF00003211449 fastq.gz 4.0 GB
EGAF00003211450 fastq.gz 4.0 GB
EGAF00003211451 fastq.gz 3.3 GB
EGAF00003211452 fastq.gz 3.3 GB
EGAF00003211453 fastq.gz 3.6 GB
EGAF00003211454 fastq.gz 3.6 GB
EGAF00003211455 fastq.gz 4.0 GB
EGAF00003211456 fastq.gz 4.0 GB
EGAF00003211457 fastq.gz 4.0 GB
EGAF00003211458 fastq.gz 4.0 GB
EGAF00003211459 fastq.gz 4.1 GB
EGAF00003211460 fastq.gz 4.1 GB
EGAF00003211461 fastq.gz 4.6 GB
EGAF00003211462 fastq.gz 4.6 GB
EGAF00003211463 fastq.gz 3.4 GB
EGAF00003211464 fastq.gz 3.4 GB
EGAF00003211465 fastq.gz 3.5 GB
EGAF00003211466 fastq.gz 3.6 GB
EGAF00003211467 fastq.gz 3.8 GB
EGAF00003211468 fastq.gz 3.7 GB
EGAF00003211469 fastq.gz 3.5 GB
EGAF00003211470 fastq.gz 3.5 GB
EGAF00003211471 fastq.gz 4.0 GB
EGAF00003211472 fastq.gz 4.0 GB
EGAF00003211473 fastq.gz 4.2 GB
EGAF00003211474 fastq.gz 4.2 GB
EGAF00003211475 fastq.gz 4.1 GB
EGAF00003211476 fastq.gz 4.1 GB
EGAF00003211477 fastq.gz 3.4 GB
EGAF00003211478 fastq.gz 3.4 GB
EGAF00003211479 fastq.gz 3.7 GB
EGAF00003211480 fastq.gz 3.7 GB
EGAF00003211481 fastq.gz 3.9 GB
EGAF00003211482 fastq.gz 4.0 GB
EGAF00003211483 fastq.gz 4.0 GB
EGAF00003211484 fastq.gz 4.0 GB
EGAF00003211485 fastq.gz 3.5 GB
EGAF00003211486 fastq.gz 3.6 GB
EGAF00003211487 fastq.gz 4.0 GB
EGAF00003211488 fastq.gz 4.0 GB
EGAF00003211489 fastq.gz 5.1 GB
EGAF00003211490 fastq.gz 5.1 GB
EGAF00003211491 fastq.gz 4.1 GB
EGAF00003211492 fastq.gz 4.1 GB
EGAF00003211493 fastq.gz 3.5 GB
EGAF00003211494 fastq.gz 3.5 GB
EGAF00003211495 fastq.gz 3.5 GB
EGAF00003211496 fastq.gz 3.5 GB
EGAF00003211497 fastq.gz 4.4 GB
EGAF00003211498 fastq.gz 4.4 GB
EGAF00003211499 fastq.gz 3.6 GB
EGAF00003211500 fastq.gz 3.5 GB
EGAF00003211501 fastq.gz 3.5 GB
EGAF00003211502 fastq.gz 3.5 GB
EGAF00003211503 fastq.gz 2.5 GB
EGAF00003211504 fastq.gz 2.5 GB
EGAF00003211505 fastq.gz 4.0 GB
EGAF00003211506 fastq.gz 4.0 GB
EGAF00003211507 fastq.gz 4.2 GB
EGAF00003211508 fastq.gz 4.2 GB
EGAF00003211509 fastq.gz 3.0 GB
EGAF00003211510 fastq.gz 3.0 GB
EGAF00003211511 fastq.gz 3.8 GB
EGAF00003211512 fastq.gz 3.8 GB
EGAF00003211513 fastq.gz 3.5 GB
EGAF00003211514 fastq.gz 3.5 GB
EGAF00003211515 fastq.gz 3.8 GB
EGAF00003211516 fastq.gz 3.8 GB
EGAF00003211517 fastq.gz 4.7 GB
EGAF00003211518 fastq.gz 4.7 GB
EGAF00003211519 fastq.gz 2.9 GB
EGAF00003211520 fastq.gz 2.9 GB
EGAF00003211521 fastq.gz 3.5 GB
EGAF00003211522 fastq.gz 3.5 GB
EGAF00003211523 fastq.gz 4.0 GB
EGAF00003211524 fastq.gz 4.0 GB
EGAF00003211525 fastq.gz 3.5 GB
EGAF00003211526 fastq.gz 3.5 GB
EGAF00003211527 fastq.gz 2.6 GB
EGAF00003211528 fastq.gz 2.6 GB
EGAF00003211529 fastq.gz 2.9 GB
EGAF00003211530 fastq.gz 2.9 GB
EGAF00003211531 fastq.gz 3.7 GB
EGAF00003211532 fastq.gz 3.7 GB
EGAF00003211533 fastq.gz 3.6 GB
EGAF00003211534 fastq.gz 3.5 GB
EGAF00003211535 fastq.gz 3.6 GB
EGAF00003211536 fastq.gz 3.6 GB
EGAF00003211537 fastq.gz 3.9 GB
EGAF00003211538 fastq.gz 3.9 GB
EGAF00003211539 fastq.gz 2.8 GB
EGAF00003211540 fastq.gz 2.8 GB
EGAF00003211541 fastq.gz 3.9 GB
EGAF00003211542 fastq.gz 3.9 GB
EGAF00003211543 fastq.gz 4.5 GB
EGAF00003211544 fastq.gz 4.4 GB
EGAF00003211545 fastq.gz 3.9 GB
EGAF00003211546 fastq.gz 3.9 GB
EGAF00003211547 fastq.gz 3.6 GB
EGAF00003211548 fastq.gz 3.6 GB
EGAF00003211549 fastq.gz 3.7 GB
EGAF00003211550 fastq.gz 3.7 GB
EGAF00003211551 fastq.gz 4.3 GB
EGAF00003211552 fastq.gz 4.3 GB
EGAF00003211553 fastq.gz 4.1 GB
EGAF00003211554 fastq.gz 4.1 GB
EGAF00003211555 fastq.gz 3.9 GB
EGAF00003211556 fastq.gz 3.9 GB
EGAF00003211557 fastq.gz 4.4 GB
EGAF00003211558 fastq.gz 4.4 GB
EGAF00003211559 fastq.gz 2.6 GB
EGAF00003211560 fastq.gz 2.6 GB
EGAF00003211561 fastq.gz 4.8 GB
EGAF00003211562 fastq.gz 4.8 GB
EGAF00003211563 fastq.gz 3.2 GB
EGAF00003211564 fastq.gz 3.2 GB
EGAF00003211565 fastq.gz 4.3 GB
EGAF00003211566 fastq.gz 4.3 GB
EGAF00003211567 fastq.gz 3.9 GB
EGAF00003211568 fastq.gz 3.9 GB
EGAF00003211569 fastq.gz 3.9 GB
EGAF00003211570 fastq.gz 3.9 GB
EGAF00003211571 fastq.gz 3.9 GB
EGAF00003211572 fastq.gz 3.9 GB
EGAF00003211573 fastq.gz 3.6 GB
EGAF00003211574 fastq.gz 3.6 GB
EGAF00003211575 fastq.gz 3.5 GB
EGAF00003211576 fastq.gz 3.5 GB
EGAF00003211577 fastq.gz 3.2 GB
EGAF00003211578 fastq.gz 3.2 GB
EGAF00003211579 fastq.gz 4.2 GB
EGAF00003211580 fastq.gz 4.2 GB
EGAF00003211581 fastq.gz 3.7 GB
EGAF00003211582 fastq.gz 3.7 GB
EGAF00003211583 fastq.gz 2.4 GB
EGAF00003211584 fastq.gz 2.4 GB
EGAF00003211585 fastq.gz 3.8 GB
EGAF00003211586 fastq.gz 3.8 GB
EGAF00003211587 fastq.gz 3.6 GB
EGAF00003211588 fastq.gz 3.6 GB
EGAF00003211589 fastq.gz 3.9 GB
EGAF00003211590 fastq.gz 3.9 GB
EGAF00003211591 fastq.gz 3.8 GB
EGAF00003211592 fastq.gz 3.8 GB
EGAF00003211593 fastq.gz 4.1 GB
EGAF00003211594 fastq.gz 4.1 GB
EGAF00003211595 fastq.gz 3.2 GB
EGAF00003211596 fastq.gz 3.2 GB
EGAF00003211597 fastq.gz 3.9 GB
EGAF00003211598 fastq.gz 3.9 GB
EGAF00003211599 fastq.gz 3.6 GB
EGAF00003211600 fastq.gz 3.6 GB
EGAF00003211601 fastq.gz 2.9 GB
EGAF00003211602 fastq.gz 2.9 GB
EGAF00003211603 fastq.gz 3.9 GB
EGAF00003211604 fastq.gz 3.9 GB
EGAF00003211605 fastq.gz 3.5 GB
EGAF00003211606 fastq.gz 3.5 GB
EGAF00003211607 fastq.gz 2.9 GB
EGAF00003211608 fastq.gz 2.9 GB
EGAF00003211609 fastq.gz 3.9 GB
EGAF00003211610 fastq.gz 3.9 GB
EGAF00003211611 fastq.gz 3.2 GB
EGAF00003211612 fastq.gz 3.2 GB
EGAF00003211613 fastq.gz 4.0 GB
EGAF00003211614 fastq.gz 4.1 GB
EGAF00003211615 fastq.gz 3.4 GB
EGAF00003211616 fastq.gz 3.4 GB
EGAF00003211617 fastq.gz 3.6 GB
EGAF00003211618 fastq.gz 3.6 GB
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EGAF00003211621 fastq.gz 4.2 GB
EGAF00003211622 fastq.gz 4.2 GB
EGAF00003211623 fastq.gz 3.1 GB
EGAF00003211624 fastq.gz 3.1 GB
EGAF00003211625 fastq.gz 3.5 GB
EGAF00003211626 fastq.gz 3.6 GB
EGAF00003211627 fastq.gz 4.0 GB
EGAF00003211628 fastq.gz 4.0 GB
EGAF00003211629 fastq.gz 3.9 GB
EGAF00003211630 fastq.gz 3.9 GB
EGAF00003211631 fastq.gz 3.7 GB
EGAF00003211632 fastq.gz 3.7 GB
EGAF00003211633 fastq.gz 3.3 GB
EGAF00003211634 fastq.gz 3.4 GB
EGAF00003211635 fastq.gz 4.8 GB
EGAF00003211636 fastq.gz 4.7 GB
EGAF00003211673 fastq.gz 4.5 GB
EGAF00003211674 fastq.gz 4.5 GB
EGAF00003211675 fastq.gz 3.8 GB
EGAF00003211676 fastq.gz 3.8 GB
EGAF00003211677 fastq.gz 3.6 GB
EGAF00003211678 fastq.gz 3.7 GB
EGAF00003211679 fastq.gz 2.8 GB
EGAF00003211680 fastq.gz 2.8 GB
EGAF00003211681 fastq.gz 4.3 GB
EGAF00003211682 fastq.gz 4.4 GB
EGAF00003211683 fastq.gz 3.8 GB
EGAF00003211684 fastq.gz 3.8 GB
EGAF00003211685 fastq.gz 3.4 GB
EGAF00003211686 fastq.gz 3.4 GB
EGAF00003211687 fastq.gz 3.1 GB
EGAF00003211688 fastq.gz 3.1 GB
EGAF00003211689 fastq.gz 3.9 GB
EGAF00003211690 fastq.gz 3.9 GB
EGAF00003211691 fastq.gz 2.8 GB
EGAF00003211692 fastq.gz 2.8 GB
EGAF00003211693 fastq.gz 4.4 GB
EGAF00003211694 fastq.gz 4.4 GB
EGAF00003211695 fastq.gz 4.1 GB
EGAF00003211696 fastq.gz 4.1 GB
EGAF00003211697 fastq.gz 3.8 GB
EGAF00003211698 fastq.gz 3.8 GB
EGAF00003211699 fastq.gz 2.8 GB
EGAF00003211700 fastq.gz 2.8 GB
EGAF00003211701 fastq.gz 4.1 GB
EGAF00003211702 fastq.gz 4.1 GB
EGAF00003211703 fastq.gz 3.3 GB
EGAF00003211704 fastq.gz 3.3 GB
EGAF00003211705 fastq.gz 3.0 GB
EGAF00003211706 fastq.gz 3.0 GB
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EGAF00003211710 fastq.gz 4.1 GB
EGAF00003211711 fastq.gz 4.4 GB
EGAF00003211712 fastq.gz 4.4 GB
EGAF00003211713 fastq.gz 4.6 GB
EGAF00003211714 fastq.gz 4.6 GB
EGAF00003211715 fastq.gz 3.7 GB
EGAF00003211716 fastq.gz 3.8 GB
EGAF00003211717 fastq.gz 3.9 GB
EGAF00003211718 fastq.gz 3.9 GB
EGAF00003211719 fastq.gz 3.0 GB
EGAF00003211720 fastq.gz 3.0 GB
EGAF00003211721 fastq.gz 3.5 GB
EGAF00003211722 fastq.gz 3.6 GB
EGAF00003211723 fastq.gz 3.9 GB
EGAF00003211724 fastq.gz 3.9 GB
EGAF00003211725 fastq.gz 3.4 GB
EGAF00003211726 fastq.gz 3.4 GB
EGAF00003211727 fastq.gz 3.3 GB
EGAF00003211728 fastq.gz 3.3 GB
EGAF00003211729 fastq.gz 3.3 GB
EGAF00003211730 fastq.gz 3.3 GB
EGAF00003211731 fastq.gz 3.6 GB
EGAF00003211732 fastq.gz 3.6 GB
EGAF00003211733 fastq.gz 3.5 GB
EGAF00003211734 fastq.gz 3.5 GB
EGAF00003211735 fastq.gz 3.1 GB
EGAF00003211736 fastq.gz 3.1 GB
EGAF00003211737 fastq.gz 3.1 GB
EGAF00003211738 fastq.gz 3.1 GB
EGAF00003211739 fastq.gz 2.3 GB
EGAF00003211740 fastq.gz 2.4 GB
EGAF00003211741 fastq.gz 4.6 GB
EGAF00003211742 fastq.gz 4.6 GB
EGAF00003211743 fastq.gz 3.5 GB
EGAF00003211744 fastq.gz 3.5 GB
EGAF00003211745 fastq.gz 3.2 GB
EGAF00003211746 fastq.gz 3.2 GB
EGAF00003211747 fastq.gz 3.9 GB
EGAF00003211748 fastq.gz 3.9 GB
EGAF00003211749 fastq.gz 4.1 GB
EGAF00003211750 fastq.gz 4.2 GB
EGAF00003211751 fastq.gz 3.5 GB
EGAF00003211752 fastq.gz 3.5 GB
EGAF00003211753 fastq.gz 1.6 GB
EGAF00003211754 fastq.gz 1.6 GB
EGAF00003211755 fastq.gz 4.0 GB
EGAF00003211756 fastq.gz 4.0 GB
EGAF00003211757 fastq.gz 3.1 GB
EGAF00003211758 fastq.gz 3.2 GB
EGAF00003211759 fastq.gz 3.6 GB
EGAF00003211760 fastq.gz 3.6 GB
EGAF00003211761 fastq.gz 3.8 GB
EGAF00003211762 fastq.gz 3.8 GB
EGAF00003211763 fastq.gz 2.6 GB
EGAF00003211764 fastq.gz 2.6 GB
EGAF00003211765 fastq.gz 4.2 GB
EGAF00003211766 fastq.gz 4.2 GB
EGAF00003211767 fastq.gz 3.6 GB
EGAF00003211768 fastq.gz 3.6 GB
EGAF00003211769 fastq.gz 4.9 GB
EGAF00003211770 fastq.gz 4.9 GB
EGAF00003211771 fastq.gz 3.6 GB
EGAF00003211772 fastq.gz 3.6 GB
EGAF00003211773 fastq.gz 3.7 GB
EGAF00003211774 fastq.gz 3.7 GB
EGAF00003211775 fastq.gz 3.5 GB
EGAF00003211776 fastq.gz 3.5 GB
EGAF00003211777 fastq.gz 4.2 GB
EGAF00003211778 fastq.gz 4.2 GB
EGAF00003211779 fastq.gz 4.4 GB
EGAF00003211780 fastq.gz 4.4 GB
EGAF00003211781 fastq.gz 4.3 GB
EGAF00003211782 fastq.gz 4.2 GB
EGAF00003211783 fastq.gz 3.9 GB
EGAF00003211784 fastq.gz 3.9 GB
EGAF00003211785 fastq.gz 3.9 GB
EGAF00003211786 fastq.gz 3.9 GB
EGAF00003211787 fastq.gz 3.7 GB
EGAF00003211788 fastq.gz 3.7 GB
EGAF00003211789 fastq.gz 3.4 GB
EGAF00003211790 fastq.gz 3.4 GB
EGAF00003211791 fastq.gz 3.4 GB
EGAF00003211792 fastq.gz 3.5 GB
EGAF00003211793 fastq.gz 4.4 GB
EGAF00003211794 fastq.gz 4.4 GB
EGAF00003211795 fastq.gz 3.6 GB
EGAF00003211796 fastq.gz 3.6 GB
EGAF00003211797 fastq.gz 4.0 GB
EGAF00003211798 fastq.gz 4.0 GB
EGAF00003211799 fastq.gz 4.1 GB
EGAF00003211800 fastq.gz 4.1 GB
EGAF00003211801 fastq.gz 3.8 GB
EGAF00003211802 fastq.gz 3.8 GB
EGAF00003211803 fastq.gz 3.6 GB
EGAF00003211804 fastq.gz 3.6 GB
EGAF00003211805 fastq.gz 3.9 GB
EGAF00003211806 fastq.gz 3.9 GB
EGAF00003211807 fastq.gz 4.4 GB
EGAF00003211808 fastq.gz 4.4 GB
EGAF00003211809 fastq.gz 4.4 GB
EGAF00003211810 fastq.gz 4.4 GB
EGAF00003211811 fastq.gz 3.4 GB
EGAF00003211812 fastq.gz 3.4 GB
EGAF00003211813 fastq.gz 3.7 GB
EGAF00003211814 fastq.gz 3.7 GB
EGAF00003211815 fastq.gz 4.0 GB
EGAF00003211816 fastq.gz 4.0 GB
EGAF00003211817 fastq.gz 3.9 GB
EGAF00003211818 fastq.gz 3.9 GB
EGAF00003211819 fastq.gz 3.5 GB
EGAF00003211820 fastq.gz 3.6 GB
EGAF00003211821 fastq.gz 3.8 GB
EGAF00003211822 fastq.gz 3.8 GB
EGAF00003211823 fastq.gz 4.0 GB
EGAF00003211824 fastq.gz 4.0 GB
EGAF00003211825 fastq.gz 4.0 GB
EGAF00003211826 fastq.gz 4.0 GB
EGAF00003211827 fastq.gz 4.3 GB
EGAF00003211828 fastq.gz 4.3 GB
EGAF00003211829 fastq.gz 3.3 GB
EGAF00003211830 fastq.gz 3.3 GB
EGAF00003211831 fastq.gz 4.2 GB
EGAF00003211832 fastq.gz 4.2 GB
EGAF00003211833 fastq.gz 4.3 GB
EGAF00003211834 fastq.gz 4.3 GB
EGAF00003211835 fastq.gz 3.4 GB
EGAF00003211836 fastq.gz 3.4 GB
EGAF00003211837 fastq.gz 3.0 GB
EGAF00003211838 fastq.gz 3.0 GB
EGAF00003211839 fastq.gz 3.9 GB
EGAF00003211840 fastq.gz 4.0 GB
EGAF00003211841 fastq.gz 3.2 GB
EGAF00003211842 fastq.gz 3.2 GB
EGAF00003211843 fastq.gz 3.3 GB
EGAF00003211844 fastq.gz 3.3 GB
EGAF00003211845 fastq.gz 4.6 GB
EGAF00003211846 fastq.gz 4.6 GB
EGAF00003211847 fastq.gz 4.4 GB
EGAF00003211848 fastq.gz 4.4 GB
EGAF00003211849 fastq.gz 4.9 GB
EGAF00003211850 fastq.gz 4.9 GB
EGAF00003211851 fastq.gz 4.3 GB
EGAF00003211852 fastq.gz 4.2 GB
EGAF00003211853 fastq.gz 3.7 GB
EGAF00003211854 fastq.gz 3.7 GB
EGAF00003211855 fastq.gz 3.0 GB
EGAF00003211856 fastq.gz 3.1 GB
EGAF00003211857 fastq.gz 4.5 GB
EGAF00003211858 fastq.gz 4.5 GB
EGAF00003211859 fastq.gz 3.9 GB
EGAF00003211860 fastq.gz 3.9 GB
EGAF00003211861 fastq.gz 4.0 GB
EGAF00003211862 fastq.gz 4.1 GB
EGAF00003211863 fastq.gz 4.5 GB
EGAF00003211864 fastq.gz 4.6 GB
EGAF00003211865 fastq.gz 3.6 GB
EGAF00003211866 fastq.gz 3.6 GB
EGAF00003211867 fastq.gz 3.5 GB
EGAF00003211868 fastq.gz 3.5 GB
EGAF00003211869 fastq.gz 3.2 GB
EGAF00003211870 fastq.gz 3.2 GB
EGAF00003211871 fastq.gz 3.5 GB
EGAF00003211872 fastq.gz 3.5 GB
EGAF00003211873 fastq.gz 3.8 GB
EGAF00003211874 fastq.gz 3.8 GB
EGAF00003211875 fastq.gz 3.5 GB
EGAF00003211876 fastq.gz 3.5 GB
EGAF00003211877 fastq.gz 3.9 GB
EGAF00003211878 fastq.gz 3.9 GB
EGAF00003211879 fastq.gz 4.2 GB
EGAF00003211880 fastq.gz 4.2 GB
EGAF00003211881 fastq.gz 4.1 GB
EGAF00003211882 fastq.gz 4.1 GB
EGAF00003211883 fastq.gz 4.1 GB
EGAF00003211884 fastq.gz 4.1 GB
EGAF00003211885 fastq.gz 4.0 GB
EGAF00003211886 fastq.gz 4.0 GB
EGAF00003211887 fastq.gz 3.8 GB
EGAF00003211888 fastq.gz 3.8 GB
EGAF00003211889 fastq.gz 4.3 GB
EGAF00003211890 fastq.gz 4.3 GB
EGAF00003211891 fastq.gz 3.7 GB
EGAF00003211892 fastq.gz 3.7 GB
EGAF00003211893 fastq.gz 4.2 GB
EGAF00003211894 fastq.gz 4.2 GB
EGAF00003211895 fastq.gz 3.9 GB
EGAF00003211896 fastq.gz 3.8 GB
EGAF00003211897 fastq.gz 4.5 GB
EGAF00003211898 fastq.gz 4.5 GB
EGAF00003211899 fastq.gz 4.2 GB
EGAF00003211900 fastq.gz 4.1 GB
EGAF00003211901 fastq.gz 3.4 GB
EGAF00003211902 fastq.gz 3.4 GB
EGAF00003211903 fastq.gz 3.4 GB
EGAF00003211904 fastq.gz 3.5 GB
EGAF00003211905 fastq.gz 3.5 GB
EGAF00003211906 fastq.gz 3.5 GB
EGAF00003211907 fastq.gz 3.2 GB
EGAF00003211908 fastq.gz 3.2 GB
EGAF00003211909 fastq.gz 3.8 GB
EGAF00003211910 fastq.gz 3.8 GB
EGAF00003211911 fastq.gz 4.2 GB
EGAF00003211912 fastq.gz 4.2 GB
EGAF00003211913 fastq.gz 2.8 GB
EGAF00003211914 fastq.gz 2.8 GB
EGAF00003211915 fastq.gz 3.5 GB
EGAF00003211916 fastq.gz 3.5 GB
EGAF00003211917 fastq.gz 2.8 GB
EGAF00003211918 fastq.gz 2.8 GB
EGAF00003211919 fastq.gz 3.2 GB
EGAF00003211920 fastq.gz 3.1 GB
EGAF00003211921 fastq.gz 3.7 GB
EGAF00003211922 fastq.gz 3.7 GB
EGAF00003211923 fastq.gz 3.9 GB
EGAF00003211924 fastq.gz 3.9 GB
EGAF00003211925 fastq.gz 4.7 GB
EGAF00003211926 fastq.gz 4.7 GB
EGAF00003211927 fastq.gz 3.7 GB
EGAF00003211928 fastq.gz 3.7 GB
EGAF00003211929 fastq.gz 4.4 GB
EGAF00003211930 fastq.gz 4.4 GB
EGAF00003211931 fastq.gz 2.8 GB
EGAF00003211932 fastq.gz 2.8 GB
EGAF00003211933 fastq.gz 4.2 GB
EGAF00003211934 fastq.gz 4.1 GB
EGAF00003211935 fastq.gz 3.8 GB
EGAF00003211936 fastq.gz 3.8 GB
EGAF00003211937 fastq.gz 4.3 GB
EGAF00003211938 fastq.gz 4.3 GB
612 Files (2.3 TB)