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Peripheral clonal expansion of T cells (scTCR-seq)

Single-cell TCR-seq of tumor-infiltrating lymphocytes from 14 cancer patients before treatment, taken from tumor, normal adjacent tissue, and peripheral blood. Dataset consists of paired-end FASTQ files, including replicate libraries and runs.

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GENENTECH DATA ACCESS COMMITTEEDATA ACCESS AGREEMENT

GENENTECH DATA ACCESS COMMITTEEDATA ACCESS AGREEMENT WITH COMMERCIAL ORGANIZATIONThis Data Access Agreement (“Agreement”) between Genentech, Inc. (“Genentech”) and User and User Organization (as defined below) governs the terms on which access will be granted to the genotype data obtained from Genentech.In signing this Agreement, User and User Organization agree to be bound by the terms and conditions of access set out in this Agreement.For the sake of clarity, the terms of access set out in this Agreement apply both to the User and the User Organization (as defined below). User Organization and User are referred to within the Agreement as “You” and “Your” shall be construed accordingly.Definitions: gRED means Genentech Research and Early Development.Data means all and any human genetic data obtained from Genentech and generated by gRED. Data Subject means a person, who has been informed of the purpose for which the Data is held and has given his/her informed consent thereto.User means a researcher whose User Organization has previously completed this Data Access Agreement and has received acknowledgement of its acceptance.Publications means, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research.User Organization means the commercial organization at which the User is employed or affiliated.Genentech Data Access Committee means members of the gRED organization that is responsible for making the data access decisions for the genotype data generated by gRED.Terms and Conditions: In signing this Agreement:1.You agree to use the Data only for the advancement of medical research.2.You agree to preserve, at all times, the confidentiality of Data pertaining to Data Subjects. In particular, You undertake not to use, or attempt to use the Data to compromise or otherwise infringe the confidentiality of information on Data Subjects and their right to privacy.3.You agree not to attempt to link the Data provided under this Agreement to other information or archive data available for the data sets provided, even if access to that data has been formally granted to you, or it is freely available without restriction, without specific permission being sought from the relevant access committees.4.You agree not to transfer or disclose the Data, in whole or part, or any identifiable material derived from the Data, to others, except as necessary for data/safety monitoring or program management. Should You wish to share the Data with a collaborator outside the same Organization, the third party must make a separate application for access to the Data.5.You agree to use the Data for the approved purpose and project described in your application; use of the Data for a new purpose or project will require a new application and approval.6.You shall be free to publish the results of the research using the Data for the approved purpose. You agree to acknowledge in any such publication that the research makes use of Data generated by Genentech/gRED.7.You accept that Genentech:a.bears no legal responsibility for the accuracy or comprehensiveness of the Data; and b.accepts no liability for indirect, consequential, or incidental, damages or losses arising from use of the Data, or from the unavailability of, or break in access to, the Data for whatever reason.8.You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out Your research with the Data, or sale of all or part of the Data on any media is not permitted.9.You recognize that nothing in this Agreement shall operate to transfer to the User Organization any intellectual property rights relating to the Data. The User Organization has the right to develop intellectual property based on the comparisons with their own data. Any invention or discovery made by User and/or User Organization arising out of the use of the Data (each a “Data Invention”) shall be promptly disclosed to Genentech in writing. User Organization hereby grants to Genentech a royalty-free, fully-paid, non-exclusive license (i) to make, use and import such Data Invention for internal research purposes; and (ii) to make, use, offer to sell, sell and import such Data Invention to the extent necessary to commercialize Genentech product(s), which license shall be sublicensable to Genentech’s affiliates and development and commercialization collaborators on such product(s). 10.You agree that you will submit a report to the Genentech Data Access Committee, if requested, on completion of the agreed purpose. The Genentech Data Access Committee agrees to treat the report and all information, data, results, and conclusions contained within such report as confidential information belonging to the User Organization.11.(a) You agree to use the Data in accordance with all applicable laws, including but not limited to applicable data privacy laws.(b) The Genentech Data Access Committee reserves the right to request and inspect data security and management documentation to ensure the adequacy of data protection measures. 12.This Agreement shall be effective as of the date of the last party to sign below (“Effective Date”) and shall terminate three (3) years after the Effective Date, unless terminated sooner pursuant to Section 13 below.13.You accept that this Agreement will terminate immediately upon any breach of this Agreement by You and You will be required to destroy any Data held. Either Party may terminate this Agreement upon thirty (30) days written notice for any reason. The following Sections of this Agreement shall survive its expiration or termination: Sections 1 – 10, 11(a), and 13. For and on behalf of User/Applicant:___________________________Signature of User/Applicant___________________________Print Name of User/Applicant___________________________Title___________________________DateFor and on behalf of User Organization:___________________________Signature of Organizational or Administrative Authority___________________________Print Name___________________________Title___________________________Name of User Organization___________________________DateFor Genentech, Inc.:___________________________Signature___________________________Print Name___________________________Title___________________________Date

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002839058 fastq.gz 2.2 GB
EGAF00002839059 fastq.gz 2.3 GB
EGAF00002839060 fastq.gz 2.1 GB
EGAF00002839061 fastq.gz 2.2 GB
EGAF00002839062 fastq.gz 2.2 GB
EGAF00002839063 fastq.gz 2.3 GB
EGAF00002839064 fastq.gz 2.1 GB
EGAF00002839065 fastq.gz 2.2 GB
EGAF00002839066 fastq.gz 2.2 GB
EGAF00002839067 fastq.gz 2.3 GB
EGAF00002839068 fastq.gz 2.2 GB
EGAF00002839069 fastq.gz 2.3 GB
EGAF00002839070 fastq.gz 4.6 GB
EGAF00002839071 fastq.gz 4.8 GB
EGAF00002839072 fastq.gz 4.4 GB
EGAF00002839073 fastq.gz 4.7 GB
EGAF00002839074 fastq.gz 4.9 GB
EGAF00002839075 fastq.gz 5.1 GB
EGAF00002839076 fastq.gz 4.7 GB
EGAF00002839077 fastq.gz 4.9 GB
EGAF00002839078 fastq.gz 3.6 GB
EGAF00002839079 fastq.gz 3.8 GB
EGAF00002839080 fastq.gz 3.5 GB
EGAF00002839081 fastq.gz 3.7 GB
EGAF00002839082 fastq.gz 3.7 GB
EGAF00002839083 fastq.gz 3.8 GB
EGAF00002839084 fastq.gz 3.5 GB
EGAF00002839085 fastq.gz 3.7 GB
EGAF00002839086 fastq.gz 3.7 GB
EGAF00002839087 fastq.gz 3.9 GB
EGAF00002839088 fastq.gz 3.2 GB
EGAF00002839089 fastq.gz 3.5 GB
EGAF00002839090 fastq.gz 3.4 GB
EGAF00002839091 fastq.gz 3.6 GB
EGAF00002839092 fastq.gz 3.5 GB
EGAF00002839093 fastq.gz 3.8 GB
EGAF00002839094 fastq.gz 4.3 GB
EGAF00002839095 fastq.gz 4.6 GB
EGAF00002839096 fastq.gz 4.4 GB
EGAF00002839097 fastq.gz 4.7 GB
EGAF00002839098 fastq.gz 4.4 GB
EGAF00002839099 fastq.gz 4.7 GB
EGAF00002839100 fastq.gz 4.4 GB
EGAF00002839101 fastq.gz 4.7 GB
EGAF00002839102 fastq.gz 3.9 GB
EGAF00002839103 fastq.gz 4.1 GB
EGAF00002839104 fastq.gz 4.0 GB
EGAF00002839105 fastq.gz 4.2 GB
EGAF00002839106 fastq.gz 3.9 GB
EGAF00002839107 fastq.gz 4.2 GB
EGAF00002839108 fastq.gz 4.0 GB
EGAF00002839109 fastq.gz 4.2 GB
EGAF00002839110 fastq.gz 2.7 GB
EGAF00002839111 fastq.gz 2.8 GB
EGAF00002839112 fastq.gz 2.7 GB
EGAF00002839113 fastq.gz 2.8 GB
EGAF00002839114 fastq.gz 2.9 GB
EGAF00002839115 fastq.gz 2.9 GB
EGAF00002839116 fastq.gz 2.8 GB
EGAF00002839117 fastq.gz 2.9 GB
EGAF00002839118 fastq.gz 692.0 MB
EGAF00002839119 fastq.gz 756.3 MB
EGAF00002839120 fastq.gz 694.6 MB
EGAF00002839121 fastq.gz 758.7 MB
EGAF00002839122 fastq.gz 2.0 GB
EGAF00002839123 fastq.gz 2.1 GB
EGAF00002839124 fastq.gz 2.0 GB
EGAF00002839125 fastq.gz 2.1 GB
EGAF00002839126 fastq.gz 762.3 MB
EGAF00002839127 fastq.gz 819.9 MB
EGAF00002839128 fastq.gz 764.2 MB
EGAF00002839129 fastq.gz 822.2 MB
EGAF00002839130 fastq.gz 2.1 GB
EGAF00002839131 fastq.gz 2.2 GB
EGAF00002839132 fastq.gz 2.1 GB
EGAF00002839133 fastq.gz 2.1 GB
EGAF00002839134 fastq.gz 716.8 MB
EGAF00002839135 fastq.gz 772.1 MB
EGAF00002839136 fastq.gz 718.8 MB
EGAF00002839137 fastq.gz 774.8 MB
EGAF00002839138 fastq.gz 2.0 GB
EGAF00002839139 fastq.gz 2.1 GB
EGAF00002839140 fastq.gz 1.9 GB
EGAF00002839141 fastq.gz 2.0 GB
EGAF00002839142 fastq.gz 1.2 GB
EGAF00002839143 fastq.gz 1.2 GB
EGAF00002839144 fastq.gz 1.2 GB
EGAF00002839145 fastq.gz 1.3 GB
EGAF00002839146 fastq.gz 1.2 GB
EGAF00002839147 fastq.gz 1.2 GB
EGAF00002839148 fastq.gz 1.2 GB
EGAF00002839149 fastq.gz 1.3 GB
EGAF00002839150 fastq.gz 1.1 GB
EGAF00002839151 fastq.gz 1.1 GB
EGAF00002839152 fastq.gz 1.1 GB
EGAF00002839153 fastq.gz 1.1 GB
EGAF00002839154 fastq.gz 827.6 MB
EGAF00002839155 fastq.gz 862.1 MB
EGAF00002839156 fastq.gz 853.8 MB
EGAF00002839157 fastq.gz 890.0 MB
EGAF00002839158 fastq.gz 1.2 GB
EGAF00002839159 fastq.gz 1.2 GB
EGAF00002839160 fastq.gz 1.2 GB
EGAF00002839161 fastq.gz 1.3 GB
EGAF00002839162 fastq.gz 1.2 GB
EGAF00002839163 fastq.gz 1.2 GB
EGAF00002839164 fastq.gz 1.2 GB
EGAF00002839165 fastq.gz 1.3 GB
EGAF00002839166 fastq.gz 1.2 GB
EGAF00002839167 fastq.gz 1.2 GB
EGAF00002839168 fastq.gz 1.2 GB
EGAF00002839169 fastq.gz 1.3 GB
EGAF00002839170 fastq.gz 5.8 GB
EGAF00002839171 fastq.gz 6.0 GB
EGAF00002839172 fastq.gz 6.0 GB
EGAF00002839173 fastq.gz 6.2 GB
EGAF00002839174 fastq.gz 5.7 GB
EGAF00002839175 fastq.gz 5.9 GB
EGAF00002839176 fastq.gz 5.9 GB
EGAF00002839177 fastq.gz 6.1 GB
EGAF00002839178 fastq.gz 5.6 GB
EGAF00002839179 fastq.gz 5.9 GB
EGAF00002839180 fastq.gz 5.8 GB
EGAF00002839181 fastq.gz 6.0 GB
EGAF00002839182 fastq.gz 3.9 GB
EGAF00002839183 fastq.gz 4.1 GB
EGAF00002839184 fastq.gz 3.9 GB
EGAF00002839185 fastq.gz 4.1 GB
EGAF00002839186 fastq.gz 3.1 GB
EGAF00002839187 fastq.gz 3.2 GB
EGAF00002839188 fastq.gz 3.1 GB
EGAF00002839189 fastq.gz 3.2 GB
EGAF00002839190 fastq.gz 3.2 GB
EGAF00002839191 fastq.gz 3.4 GB
EGAF00002839192 fastq.gz 3.2 GB
EGAF00002839193 fastq.gz 3.4 GB
EGAF00002839194 fastq.gz 3.0 GB
EGAF00002839195 fastq.gz 3.2 GB
EGAF00002839196 fastq.gz 3.0 GB
EGAF00002839197 fastq.gz 3.2 GB
EGAF00002839198 fastq.gz 4.9 GB
EGAF00002839199 fastq.gz 5.0 GB
EGAF00002839200 fastq.gz 4.9 GB
EGAF00002839201 fastq.gz 5.0 GB
EGAF00002839202 fastq.gz 3.6 GB
EGAF00002839203 fastq.gz 3.7 GB
EGAF00002839204 fastq.gz 3.6 GB
EGAF00002839205 fastq.gz 3.7 GB
EGAF00002839206 fastq.gz 3.8 GB
EGAF00002839207 fastq.gz 3.9 GB
EGAF00002839208 fastq.gz 3.8 GB
EGAF00002839209 fastq.gz 3.9 GB
EGAF00002839210 fastq.gz 7.3 GB
EGAF00002839211 fastq.gz 7.6 GB
EGAF00002839212 fastq.gz 7.2 GB
EGAF00002839213 fastq.gz 7.5 GB
EGAF00002839214 fastq.gz 9.7 GB
EGAF00002839215 fastq.gz 10.0 GB
EGAF00002839216 fastq.gz 9.6 GB
EGAF00002839217 fastq.gz 9.9 GB
EGAF00002839218 fastq.gz 7.3 GB
EGAF00002839219 fastq.gz 7.6 GB
EGAF00002839220 fastq.gz 7.2 GB
EGAF00002839221 fastq.gz 7.5 GB
EGAF00002839222 fastq.gz 3.3 GB
EGAF00002839223 fastq.gz 3.4 GB
EGAF00002839224 fastq.gz 3.2 GB
EGAF00002839225 fastq.gz 3.3 GB
EGAF00002839226 fastq.gz 3.0 GB
EGAF00002839227 fastq.gz 3.1 GB
EGAF00002839228 fastq.gz 2.9 GB
EGAF00002839229 fastq.gz 3.0 GB
EGAF00002839230 fastq.gz 3.1 GB
EGAF00002839231 fastq.gz 3.2 GB
EGAF00002839232 fastq.gz 3.0 GB
EGAF00002839233 fastq.gz 3.1 GB
176 Files (590.7 GB)