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single cell RNA-seq of bone marrow from infants with MLL-rearranged Acute Lymphoblastic Leukemia by single cell RNA-sequencing

This dataset contains two experiments. 1) Single cell RNA-seq of diagnostic samples from patients with MLL-rearranged infant ALL that underwent relapse or not (samples ending in R relapsed, samples ending in N did not). For some of the patients, multiple indipendent plates were produced (each plate is a sample). 2) in vitro prednisolone exposure experiment. diagnostic bone marrow samples from patient 4662R were cultured for three days with and without prednisolone. Single cell experiments were conducted according to Muraro et al (cell systems, 2016, doi:10.1016/j.cels.2016.09.002). Cell barcodes and UMI sequences are embedded in the header of each fastq entry. Cell barcodes irrelevant to this experiment were removed before submission.

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002838531 fastq.gz 1.7 GB
EGAF00002838532 fastq.gz 1.0 GB
EGAF00002838533 fastq.gz 252.5 MB
EGAF00002838534 fastq.gz 2.8 GB
EGAF00002838535 fastq.gz 565.4 MB
EGAF00002838536 fastq.gz 951.6 MB
EGAF00002838537 fastq.gz 5.7 GB
EGAF00002838538 fastq.gz 2.0 GB
EGAF00002838539 fastq.gz 795.2 MB
EGAF00002838540 fastq.gz 1.9 GB
EGAF00002838541 fastq.gz 1.6 GB
EGAF00002838542 fastq.gz 1.7 GB
12 Files (21.1 GB)