A compendium of mutational signatures due to environmental exposures
Analysis of mutational signatures caused by exposure to known mutagens in human induced pluripotent stem (iPS) cells. A reference human iPS cell-line will be exposed to 100 chemicals known or proposed to be mutagenic. Following exposure to mutagen, cells will undergo a period of recovery before sub clones are generated and sequenced. The progenitor "parental" IPS cell-line will be used to generate reference sequence data, in order to determine the mutational signatures acquired as a result of exposure to different mutagens.
- 6 samples
- DAC: EGAC00001000205
- Technology: HiSeq X Ten
Wellcome Trust Sanger Institute Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| Whole Genome Sequencing |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00002374179 | cram | 45.1 GB | ||
| EGAF00002374180 | cram | 35.5 GB | ||
| EGAF00002374181 | cram | 33.8 GB | ||
| EGAF00002374182 | cram | 5.3 GB | ||
| EGAF00002384070 | cram | 141.0 MB | ||
| EGAF00002384071 | cram | 125.9 MB | ||
| EGAF00002384072 | cram | 118.5 MB | ||
| EGAF00002384073 | cram | 112.6 MB | ||
| EGAF00002384074 | cram | 156.6 MB | ||
| EGAF00002384075 | cram | 157.5 MB | ||
| EGAF00002384076 | cram | 11.2 GB | ||
| 11 Files (131.7 GB) | ||||