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Clonality of circulating tumor cells in breast cancer brain metastases patients

The incidence of brain metastases in breast cancer (BCBM) patients is increasing. These patients have a very poor prognosis and therefore identification of blood-based biomarkers, such as circulating tumor cells (CTCs) and understanding the genomic heterogeneity could help to personalize treatment options. In this study, DNA from individual CTCs as well as corresponding primary tumors and brain metastases were analyzed by next generation sequencing (NGS) in order to evaluate copy number aberrations and single nucleotide variations (SNVs).

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00000827831 cram 2.3 GB
EGAF00000827832 cram 2.3 GB
EGAF00000827833 cram 2.5 GB
EGAF00000827834 cram 2.4 GB
EGAF00000827835 cram 2.1 GB
EGAF00000827836 cram 2.4 GB
EGAF00000827837 cram 2.2 GB
EGAF00000827838 cram 2.0 GB
EGAF00000827839 cram 2.3 GB
EGAF00000827840 cram 2.4 GB
EGAF00000827841 cram 2.5 GB
EGAF00000827843 cram 1.7 GB
EGAF00000827868 cram 2.5 GB
EGAF00000827869 cram 2.2 GB
EGAF00000827870 cram 2.4 GB
EGAF00000827871 cram 2.3 GB
EGAF00000827872 cram 2.0 GB
EGAF00000827881 cram 2.6 GB
EGAF00000827882 cram 2.7 GB
EGAF00000827883 cram 2.6 GB
EGAF00000827884 cram 2.8 GB
EGAF00000827885 cram 2.8 GB
EGAF00000827888 cram 2.5 GB
EGAF00000827889 cram 2.6 GB
EGAF00000827890 cram 2.5 GB
EGAF00000827891 cram 2.8 GB
EGAF00000827892 cram 2.7 GB
EGAF00000827949 cram 2.2 GB
EGAF00000827952 cram 2.8 GB
EGAF00000827953 cram 2.3 GB
EGAF00000827954 cram 2.2 GB
EGAF00000827955 cram 3.1 GB
EGAF00000827956 cram 2.2 GB
EGAF00000827959 cram 2.7 GB
EGAF00000827960 cram 2.3 GB
EGAF00000827961 cram 2.1 GB
EGAF00000827962 cram 3.0 GB
EGAF00000827963 cram 2.9 GB
EGAF00000827964 cram 2.0 GB
EGAF00000827965 cram 2.4 GB
EGAF00000827968 cram 1.8 GB
EGAF00000827970 cram 2.8 GB
EGAF00000827971 cram 2.0 GB
EGAF00000827972 cram 2.4 GB
EGAF00000830359 cram 2.2 GB
EGAF00000830367 cram 2.2 GB
EGAF00000830369 cram 2.8 GB
EGAF00000830372 cram 2.5 GB
EGAF00000830373 cram 2.9 GB
EGAF00000830374 cram 2.9 GB
EGAF00000830375 cram 2.4 GB
EGAF00000830377 cram 2.8 GB
EGAF00000830380 cram 2.5 GB
EGAF00000830381 cram 2.9 GB
EGAF00000830382 cram 2.8 GB
EGAF00000830383 cram 2.4 GB
56 Files (137.7 GB)