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MiRNome_pituitary_adenoma

Small RNA (<100 bases in length) were purified from total RNA using miRNeasy kit (Qiagen), then sequenced. Libraries were prepared at the Genomics Platform of the Cochin Institute, following the TruSeq small RNA protocol (Illumina), starting from 1 µg of high quality total RNA. Single read (1 × 75 bp) sequencing was performed on a Nextseq 500 platform (Illumina). FASTQ sequences were aligned on miRBase v.2052, then counted with STAR (v.2.5.2a).

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DATA ACCESS AGREEMENT

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom AREP grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: AREP and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. AREP: Association pour la Recherche et l’Enseignement en Pathologie Laboratoire de Pathologie Hopital Ambroise Paré 9 avenue Charles de Gaulle 92104 Boulogne-Billancourt cedex 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify AREP within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify AREP prior to any significant changes to the protocol for the Project. 14. The User Institution will notify AREP as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. AREP may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than AREP. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of France and shall be subject to the exclusive jurisdiction of the French courts. Specific limitations on areas of research This research is aimed at studying the genomic alterations occurring in pituitary adenomas. Therefore these data can only be used for analyzing the SOMATIC genome and epigenome, formally EXCLUDING any study focusing on the GERMLINE genome of individuals included in this project.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002455257 fastq.gz 1.6 GB
EGAF00002455258 bam 42.6 MB
EGAF00002455259 fastq.gz 2.0 GB
EGAF00002455260 bam 232.3 MB
EGAF00002455261 fastq.gz 3.1 GB
EGAF00002455262 bam 27.3 MB
EGAF00002455263 fastq.gz 3.5 GB
EGAF00002455264 fastq.gz 4.2 GB
EGAF00002455265 bam 151.6 MB
EGAF00002455266 bam 61.8 MB
EGAF00002455267 fastq.gz 2.4 GB
EGAF00002455268 fastq.gz 2.3 GB
EGAF00002455269 bam 31.8 MB
EGAF00002455270 fastq.gz 1.4 GB
EGAF00002455271 bam 105.4 MB
EGAF00002455272 fastq.gz 2.6 GB
EGAF00002455273 bam 84.9 MB
EGAF00002455274 fastq.gz 1.9 GB
EGAF00002455275 bam 35.2 MB
EGAF00002455276 fastq.gz 1.9 GB
EGAF00002455277 bam 103.1 MB
EGAF00002455278 fastq.gz 1.5 GB
EGAF00002455279 bam 106.5 MB
EGAF00002455280 fastq.gz 2.6 GB
EGAF00002455281 bam 54.7 MB
EGAF00002455315 fastq.gz 3.4 GB
EGAF00002455316 bam 185.4 MB
EGAF00002455317 fastq.gz 3.4 GB
EGAF00002455318 bam 106.3 MB
EGAF00002455319 fastq.gz 1.5 GB
EGAF00002455320 bam 89.4 MB
EGAF00002455321 fastq.gz 2.9 GB
EGAF00002455322 bam 134.1 MB
EGAF00002455323 fastq.gz 2.2 GB
EGAF00002455324 bam 85.7 MB
EGAF00002455325 fastq.gz 2.3 GB
EGAF00002455326 bam 104.1 MB
EGAF00002455327 fastq.gz 2.5 GB
EGAF00002455328 bam 73.7 MB
EGAF00002455329 fastq.gz 1.9 GB
EGAF00002455330 bam 74.5 MB
EGAF00002455331 fastq.gz 5.2 GB
EGAF00002455332 bam 148.1 MB
EGAF00002455333 fastq.gz 2.2 GB
EGAF00002455334 bam 102.9 MB
EGAF00002455335 fastq.gz 5.0 GB
EGAF00002455336 bam 134.6 MB
EGAF00002455337 fastq.gz 1.9 GB
EGAF00002455338 bam 78.9 MB
EGAF00002455339 fastq.gz 1.6 GB
EGAF00002455585 bam 140.8 MB
EGAF00002455586 fastq.gz 3.1 GB
EGAF00002455587 bam 121.8 MB
EGAF00002455588 fastq.gz 2.5 GB
EGAF00002455638 bam 99.1 MB
EGAF00002455639 fastq.gz 1.9 GB
EGAF00002455640 bam 98.8 MB
EGAF00002455641 fastq.gz 3.2 GB
EGAF00002455642 bam 113.4 MB
EGAF00002455643 fastq.gz 1.7 GB
EGAF00002455644 bam 109.4 MB
EGAF00002455645 fastq.gz 1.9 GB
EGAF00002455646 bam 73.6 MB
EGAF00002455647 fastq.gz 4.3 GB
EGAF00002455648 bam 122.8 MB
EGAF00002455649 fastq.gz 3.3 GB
EGAF00002455650 bam 132.5 MB
EGAF00002455652 fastq.gz 2.8 GB
EGAF00002455653 bam 100.5 MB
EGAF00002455655 fastq.gz 2.4 GB
EGAF00002455656 bam 88.1 MB
EGAF00002455658 fastq.gz 2.7 GB
EGAF00002455659 bam 122.9 MB
EGAF00002455661 fastq.gz 2.9 GB
EGAF00002455662 bam 111.5 MB
EGAF00002455696 fastq.gz 4.1 GB
EGAF00002455697 bam 128.3 MB
EGAF00002455699 bam 83.2 MB
EGAF00002455700 fastq.gz 1.6 GB
EGAF00002455702 bam 145.3 MB
EGAF00002455703 fastq.gz 3.8 GB
EGAF00002455705 bam 127.7 MB
EGAF00002455706 fastq.gz 1.9 GB
EGAF00002455708 bam 123.5 MB
EGAF00002455709 fastq.gz 3.3 GB
EGAF00002455711 bam 148.5 MB
EGAF00002455712 fastq.gz 1.8 GB
EGAF00002455714 fastq.gz 3.1 GB
EGAF00002455715 bam 177.7 MB
EGAF00002455717 bam 84.9 MB
EGAF00002455718 fastq.gz 3.4 GB
EGAF00002455732 bam 93.7 MB
EGAF00002455736 bam 154.9 MB
EGAF00002455740 bam 74.3 MB
EGAF00002455744 bam 129.1 MB
EGAF00002455749 bam 89.2 MB
EGAF00002455752 bam 81.1 MB
EGAF00002455754 fastq.gz 1.8 GB
EGAF00002455755 bam 76.2 MB
EGAF00002455757 fastq.gz 1.8 GB
EGAF00002455758 bam 103.1 MB
EGAF00002455760 fastq.gz 4.1 GB
EGAF00002455761 fastq.gz 4.4 GB
EGAF00002455762 bam 39.9 MB
EGAF00002455764 bam 89.8 MB
EGAF00002455766 fastq.gz 3.5 GB
EGAF00002455768 bam 75.9 MB
EGAF00002455769 fastq.gz 3.6 GB
EGAF00002455770 fastq.gz 3.6 GB
EGAF00002455771 bam 120.5 MB
EGAF00002455773 bam 68.0 MB
EGAF00002455774 fastq.gz 2.9 GB
EGAF00002455776 bam 81.8 MB
EGAF00002455777 bam 96.5 MB
EGAF00002455781 bam 63.6 MB
EGAF00002455786 bam 112.1 MB
EGAF00002455790 bam 246.4 MB
EGAF00002455794 bam 78.9 MB
EGAF00002455798 bam 70.1 MB
EGAF00002455802 bam 52.4 MB
EGAF00002455806 bam 132.9 MB
EGAF00002455807 fastq.gz 2.6 GB
EGAF00002455809 bam 118.3 MB
EGAF00002455810 fastq.gz 3.3 GB
EGAF00002455812 bam 103.0 MB
EGAF00002455813 fastq.gz 6.0 GB
EGAF00002455815 fastq.gz 3.0 GB
EGAF00002455817 fastq.gz 2.4 GB
EGAF00002455819 fastq.gz 5.3 GB
EGAF00002455821 fastq.gz 2.4 GB
EGAF00002455823 fastq.gz 3.9 GB
EGAF00002455825 fastq.gz 1.1 GB
EGAF00002455827 fastq.gz 5.2 GB
EGAF00002455829 fastq.gz 4.6 GB
EGAF00002455831 fastq.gz 4.4 GB
EGAF00002455835 bam 100.3 MB
EGAF00002455838 bam 122.8 MB
EGAF00002455841 bam 85.7 MB
EGAF00002455844 bam 37.0 MB
EGAF00002455847 bam 56.5 MB
EGAF00002455850 bam 208.5 MB
EGAF00002455853 bam 139.7 MB
EGAF00002455854 fastq.gz 2.5 GB
EGAF00002455857 bam 190.4 MB
EGAF00002455858 fastq.gz 2.8 GB
EGAF00002455861 bam 87.2 MB
EGAF00002455862 fastq.gz 1.8 GB
EGAF00002455864 fastq.gz 2.2 GB
EGAF00002455865 fastq.gz 5.3 GB
EGAF00002455867 fastq.gz 1.7 GB
EGAF00002455869 fastq.gz 4.3 GB
EGAF00002455872 fastq.gz 4.5 GB
EGAF00002455874 fastq.gz 2.6 GB
EGAF00002455876 fastq.gz 1.3 GB
EGAF00002455878 fastq.gz 1.8 GB
EGAF00002455880 fastq.gz 3.8 GB
EGAF00002455884 fastq.gz 2.3 GB
EGAF00002455892 bam 62.2 MB
EGAF00002455893 fastq.gz 3.6 GB
EGAF00002455896 fastq.gz 1.7 GB
EGAF00002455897 bam 144.0 MB
EGAF00002455900 fastq.gz 2.2 GB
EGAF00002455901 bam 35.4 MB
EGAF00002455902 bam 157.1 MB
EGAF00002455905 fastq.gz 1.9 GB
EGAF00002455906 bam 234.1 MB
EGAF00002455907 fastq.gz 2.7 GB
EGAF00002455910 bam 160.9 MB
EGAF00002455911 fastq.gz 4.8 GB
EGAF00002455914 bam 123.7 MB
EGAF00002455915 fastq.gz 3.1 GB
EGAF00002455918 bam 108.7 MB
EGAF00002455919 fastq.gz 2.5 GB
EGAF00002455954 bam 110.1 MB
EGAF00002455955 fastq.gz 1.8 GB
EGAF00002455958 fastq.gz 2.9 GB
EGAF00002455959 bam 131.7 MB
EGAF00002455962 bam 49.6 MB
EGAF00002455963 fastq.gz 2.1 GB
EGAF00002455966 fastq.gz 2.1 GB
EGAF00002455967 bam 37.8 MB
EGAF00002455970 fastq.gz 2.0 GB
EGAF00002455971 bam 80.0 MB
EGAF00002455972 fastq.gz 1.4 GB
EGAF00002455975 bam 43.9 MB
EGAF00002455976 fastq.gz 1.8 GB
EGAF00002455979 bam 37.0 MB
EGAF00002455980 fastq.gz 5.7 GB
EGAF00002455981 bam 34.4 MB
EGAF00002456017 fastq.gz 3.1 GB
EGAF00002456018 bam 234.3 MB
EGAF00002456021 bam 155.6 MB
EGAF00002456022 fastq.gz 4.2 GB
EGAF00002456025 bam 108.5 MB
EGAF00002456026 fastq.gz 3.6 GB
EGAF00002456029 bam 55.9 MB
EGAF00002456030 fastq.gz 1.2 GB
EGAF00002456033 bam 34.4 MB
EGAF00002456034 fastq.gz 3.3 GB
EGAF00002456037 bam 59.8 MB
EGAF00002456038 fastq.gz 1.6 GB
EGAF00002456039 bam 33.2 MB
EGAF00002456042 fastq.gz 3.6 GB
EGAF00002456045 bam 54.6 MB
EGAF00002456079 fastq.gz 5.6 GB
EGAF00002456080 bam 33.2 MB
EGAF00002456083 fastq.gz 4.6 GB
EGAF00002456084 bam 76.4 MB
EGAF00002456085 fastq.gz 2.6 GB
EGAF00002456088 fastq.gz 2.6 GB
EGAF00002456089 bam 66.7 MB
EGAF00002456092 fastq.gz 2.8 GB
EGAF00002456093 bam 51.6 MB
EGAF00002456096 bam 41.3 MB
EGAF00002456097 fastq.gz 3.6 GB
EGAF00002456100 bam 81.6 MB
EGAF00002456101 fastq.gz 2.0 GB
EGAF00002456102 bam 43.2 MB
EGAF00002456103 fastq.gz 2.9 GB
EGAF00002456104 bam 76.4 MB
EGAF00002456105 fastq.gz 1.7 GB
EGAF00002456106 bam 54.4 MB
222 Files (332.1 GB)