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Genetic vulnerability of knockout cancer lines (2019-04-01)

Genome-wide CRISPR/Cas9 library screen was performed in isogenic cell lines. Three biological replicates were used. Cells were harvested at initiation of screen and at specific time points following cell culture. Using this approach we aim to identify genes specifically important in cell survival in engineered cell lines. Please perform 72, instead of 36, PCR reactions as the screen performed at 200x coverage. . This dataset contains all the data available for this study on 2019-04-01.

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Wellcome Trust Sanger Institute Data Sharing Policy

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00001995379 cram 299.2 MB
EGAF00001995380 cram 283.4 MB
EGAF00001995381 cram 312.8 MB
EGAF00001995382 cram 302.8 MB
EGAF00001995383 cram 260.6 MB
EGAF00001995384 cram 285.8 MB
EGAF00001995385 cram 299.4 MB
EGAF00001995386 cram 283.7 MB
EGAF00001995387 cram 313.5 MB
EGAF00001995388 cram 303.4 MB
EGAF00001995389 cram 260.8 MB
EGAF00001995390 cram 286.0 MB
EGAF00001995391 cram 350.5 MB
EGAF00001995392 cram 329.9 MB
EGAF00001995393 cram 310.4 MB
EGAF00001995394 cram 358.3 MB
EGAF00001995395 cram 324.8 MB
EGAF00001995396 cram 328.4 MB
EGAF00001995397 cram 360.1 MB
EGAF00001995398 cram 338.7 MB
EGAF00001995399 cram 319.4 MB
EGAF00001995400 cram 368.4 MB
EGAF00001995401 cram 334.3 MB
EGAF00001995402 cram 336.6 MB
EGAF00001995403 cram 301.3 MB
EGAF00001995404 cram 340.3 MB
EGAF00001995405 cram 301.8 MB
EGAF00001995406 cram 294.7 MB
EGAF00001995407 cram 314.5 MB
EGAF00001995453 cram 290.3 MB
EGAF00001995454 cram 300.0 MB
EGAF00001995455 cram 339.2 MB
EGAF00001995456 cram 301.2 MB
EGAF00001995457 cram 293.8 MB
EGAF00001995458 cram 314.3 MB
EGAF00001995459 cram 289.1 MB
36 Files (11.2 GB)