Extreme intratumor heterogeneity and driver evolution in mismatch repair deficient gastro-esophageal cancer
The dataset includes multi-region exome sequencing (MSeq) of four resected treatment naïve mismatch repair deficient gastro-esophageal cancers. Paired-end sequencing was performed on the Illumina HiSeq 2500 or NovaSeq 6000 with a target depth of 200X. Seven primary tumor regions along with tumor-adjacent non malignant tissue were subjected to MSeq. An additional two lymph node metastases were also included from each of two cases.
- 35 samples
- DAC: EGAC00001001092
- Technologies: Illumina HiSeq 2500, Illumina NovaSeq 6000
Access to data will be granted to qualified researchers for academic/non-commercial research use subject to signing a data transfer agreement which restricts publication and dissemination of the the dataset and which prohibits any attempt to re-identify any of the study patients. If you need to request access to this data set, please contact: Translational Oncogenomics Lab - Data Access Committee marco.gerlinger@icr.ac.uk
Access to data will be granted to qualified researchers for academic/non-commercial research use subject to signing a data transfer agreement which restricts publication and dissemination of the the dataset and which prohibits any attempt to re-identify any of the study patients. If you need to request access to this data set, please contact: Translational Oncogenomics Lab - Data Access Committee marco.gerlinger@icr.ac.uk
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001003434 | Cancer Genomics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00002337983 | bam | 9.3 GB | ||
| EGAF00002337984 | bam | 4.9 GB | ||
| EGAF00002337985 | bam | 9.4 GB | ||
| EGAF00002337986 | bam | 10.5 GB | ||
| EGAF00002337987 | bam | 10.1 GB | ||
| EGAF00002337988 | bam | 10.8 GB | ||
| EGAF00002337989 | bam | 9.8 GB | ||
| EGAF00002337990 | bam | 9.4 GB | ||
| EGAF00002337991 | bam | 10.8 GB | ||
| EGAF00002337992 | bam | 10.2 GB | ||
| EGAF00002337993 | bam | 9.8 GB | ||
| EGAF00002337994 | bam | 4.4 GB | ||
| EGAF00002337995 | bam | 9.5 GB | ||
| EGAF00002337996 | bam | 10.4 GB | ||
| EGAF00002337997 | bam | 9.6 GB | ||
| EGAF00002337998 | bam | 9.3 GB | ||
| EGAF00002337999 | bam | 11.3 GB | ||
| EGAF00002338000 | bam | 9.2 GB | ||
| EGAF00002338001 | bam | 9.8 GB | ||
| EGAF00002338002 | bam | 9.5 GB | ||
| EGAF00002338003 | bam | 18.5 GB | ||
| EGAF00002338004 | bam | 18.2 GB | ||
| EGAF00002338005 | bam | 19.9 GB | ||
| EGAF00002338006 | bam | 19.4 GB | ||
| EGAF00002338008 | bam | 16.3 GB | ||
| EGAF00002338009 | bam | 17.3 GB | ||
| EGAF00002338010 | bam | 18.7 GB | ||
| EGAF00002338011 | bam | 9.1 GB | ||
| EGAF00002338012 | bam | 18.7 GB | ||
| EGAF00002338013 | bam | 19.2 GB | ||
| EGAF00002338014 | bam | 16.5 GB | ||
| EGAF00002338015 | bam | 16.2 GB | ||
| EGAF00002338016 | bam | 17.2 GB | ||
| EGAF00002338017 | bam | 17.9 GB | ||
| EGAF00002338018 | bam | 18.7 GB | ||
| 35 Files (449.6 GB) | ||||