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Single cell multiomics sequencing and analyses of human colorectal cancer

Whole genome sequencing data of tumor tissues, adjacent normal tissues, and peripheral blood from CRC patients.

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Data access policy of sequencing data from BIOPIC, Peking University

Data access policy of sequencing data from BIOPIC, Peking University --------------------------------------------------------------------------------- DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom Peking University BIOPIC Data Access Committee (PUBDAC) grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: Peking University BIOPIC Data Access Committee (PUBDAC) and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. Peking University BIOPIC Data Access Committee (PUBDAC): PUBDAC is composed of senior employees with appropriate scientific, bioethics, and human subjects’ research expertise. Members may be appointed for a specified term as defined by the convening Institute or serve more than one term. Consultants with specific expertise may be invited to meetings or to provide written consultation. Consultants may be PKU or non-PKU employees, and are not voting members of the DAC. Timelines for responding to requests for data access will vary, but PKUDAC will strive to provide decisions or feedback to requesting investigators in a timely manner. ?1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (https://wellcome.ac.uk/sites/default/files/wtd003207.pdf) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify Peking University BIOPIC Data Access Committee (PUBDAC) within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify Peking University BIOPIC Data Access Committee (PUBDAC) prior to any significant changes to the protocol for the Project. 14. The User Institution will notify Peking University BIOPIC Data Access Committee (PUBDAC) as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. Peking University BIOPIC Data Access Committee (PUBDAC) may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than Peking University BIOPIC Data Access Committee (PUBDAC). In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of China and shall be subject to the exclusive jurisdiction of the Chinese courts. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for Peking University BIOPIC Data Access Committee (PUBDAC) Signature: Name: Title: Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002197566 fastq.gz 3.6 GB
EGAF00002197567 fastq.gz 4.3 GB
EGAF00002197568 fastq.gz 3.0 GB
EGAF00002197569 fastq.gz 3.4 GB
EGAF00002197570 fastq.gz 2.8 GB
EGAF00002197571 fastq.gz 3.2 GB
EGAF00002197572 fastq.gz 2.8 GB
EGAF00002197573 fastq.gz 3.2 GB
EGAF00002197574 fastq.gz 6.7 GB
EGAF00002197575 fastq.gz 7.5 GB
EGAF00002197576 fastq.gz 2.0 GB
EGAF00002197577 fastq.gz 2.5 GB
EGAF00002197578 fastq.gz 2.0 GB
EGAF00002197579 fastq.gz 2.3 GB
EGAF00002197580 fastq.gz 1.4 GB
EGAF00002197581 fastq.gz 1.5 GB
EGAF00002197582 fastq.gz 2.0 GB
EGAF00002197583 fastq.gz 2.3 GB
EGAF00002197584 fastq.gz 2.3 GB
EGAF00002197585 fastq.gz 2.5 GB
EGAF00002197586 fastq.gz 2.3 GB
EGAF00002197587 fastq.gz 2.6 GB
EGAF00002197588 fastq.gz 2.6 GB
EGAF00002197589 fastq.gz 2.8 GB
EGAF00002197590 fastq.gz 2.3 GB
EGAF00002197591 fastq.gz 2.8 GB
EGAF00002197592 fastq.gz 2.3 GB
EGAF00002197593 fastq.gz 2.6 GB
EGAF00002197594 fastq.gz 1.6 GB
EGAF00002197595 fastq.gz 1.7 GB
EGAF00002197596 fastq.gz 2.3 GB
EGAF00002197597 fastq.gz 2.6 GB
EGAF00002197598 fastq.gz 2.5 GB
EGAF00002197599 fastq.gz 2.8 GB
EGAF00002197600 fastq.gz 2.6 GB
EGAF00002197601 fastq.gz 2.9 GB
EGAF00002197602 fastq.gz 2.9 GB
EGAF00002197603 fastq.gz 3.2 GB
EGAF00002197604 fastq.gz 2.1 GB
EGAF00002197605 fastq.gz 2.6 GB
EGAF00002197606 fastq.gz 2.1 GB
EGAF00002197607 fastq.gz 2.3 GB
EGAF00002197608 fastq.gz 1.4 GB
EGAF00002197609 fastq.gz 1.5 GB
EGAF00002197610 fastq.gz 2.1 GB
EGAF00002197611 fastq.gz 2.3 GB
EGAF00002197612 fastq.gz 2.3 GB
EGAF00002197613 fastq.gz 2.5 GB
EGAF00002197614 fastq.gz 2.4 GB
EGAF00002197615 fastq.gz 2.6 GB
EGAF00002197616 fastq.gz 2.6 GB
EGAF00002197617 fastq.gz 2.9 GB
EGAF00002197618 fastq.gz 2.0 GB
EGAF00002197619 fastq.gz 2.5 GB
EGAF00002197620 fastq.gz 1.9 GB
EGAF00002197621 fastq.gz 2.2 GB
EGAF00002197622 fastq.gz 1.3 GB
EGAF00002197623 fastq.gz 1.5 GB
EGAF00002197624 fastq.gz 1.9 GB
EGAF00002197625 fastq.gz 2.2 GB
EGAF00002197626 fastq.gz 2.1 GB
EGAF00002197627 fastq.gz 2.4 GB
EGAF00002197628 fastq.gz 2.2 GB
EGAF00002197629 fastq.gz 2.5 GB
EGAF00002197630 fastq.gz 2.5 GB
EGAF00002197631 fastq.gz 2.7 GB
EGAF00002197632 fastq.gz 2.1 GB
EGAF00002197633 fastq.gz 2.5 GB
EGAF00002197634 fastq.gz 2.1 GB
EGAF00002197635 fastq.gz 2.3 GB
EGAF00002197636 fastq.gz 1.4 GB
EGAF00002197637 fastq.gz 1.6 GB
EGAF00002197638 fastq.gz 2.1 GB
EGAF00002197639 fastq.gz 2.3 GB
EGAF00002197640 fastq.gz 2.3 GB
EGAF00002197641 fastq.gz 2.5 GB
EGAF00002197642 fastq.gz 2.4 GB
EGAF00002197643 fastq.gz 2.6 GB
EGAF00002197644 fastq.gz 2.7 GB
EGAF00002197645 fastq.gz 2.9 GB
EGAF00002197646 fastq.gz 2.3 GB
EGAF00002197647 fastq.gz 2.7 GB
EGAF00002197648 fastq.gz 2.2 GB
EGAF00002197649 fastq.gz 2.5 GB
EGAF00002197650 fastq.gz 1.5 GB
EGAF00002197651 fastq.gz 1.6 GB
EGAF00002197652 fastq.gz 2.2 GB
EGAF00002197653 fastq.gz 2.5 GB
EGAF00002197654 fastq.gz 2.4 GB
EGAF00002197655 fastq.gz 2.7 GB
EGAF00002197656 fastq.gz 2.5 GB
EGAF00002197657 fastq.gz 2.8 GB
EGAF00002197658 fastq.gz 2.9 GB
EGAF00002197659 fastq.gz 3.1 GB
EGAF00002197660 fastq.gz 1.9 GB
EGAF00002197661 fastq.gz 2.3 GB
EGAF00002197662 fastq.gz 1.9 GB
EGAF00002197663 fastq.gz 2.1 GB
EGAF00002197664 fastq.gz 1.3 GB
EGAF00002197665 fastq.gz 1.4 GB
EGAF00002197666 fastq.gz 1.9 GB
EGAF00002197667 fastq.gz 2.1 GB
EGAF00002197668 fastq.gz 2.1 GB
EGAF00002197669 fastq.gz 2.3 GB
EGAF00002197670 fastq.gz 2.1 GB
EGAF00002197671 fastq.gz 2.3 GB
EGAF00002197672 fastq.gz 2.4 GB
EGAF00002197673 fastq.gz 2.6 GB
EGAF00002197674 fastq.gz 2.0 GB
EGAF00002197675 fastq.gz 2.3 GB
EGAF00002197676 fastq.gz 1.9 GB
EGAF00002197677 fastq.gz 2.1 GB
EGAF00002197678 fastq.gz 1.3 GB
EGAF00002197679 fastq.gz 1.4 GB
EGAF00002197680 fastq.gz 1.9 GB
EGAF00002197681 fastq.gz 2.1 GB
EGAF00002197682 fastq.gz 2.1 GB
EGAF00002197683 fastq.gz 2.3 GB
EGAF00002197684 fastq.gz 2.2 GB
EGAF00002197685 fastq.gz 2.4 GB
EGAF00002197686 fastq.gz 2.5 GB
EGAF00002197687 fastq.gz 2.6 GB
EGAF00002197688 fastq.gz 1.5 GB
EGAF00002197689 fastq.gz 1.8 GB
EGAF00002197690 fastq.gz 1.8 GB
EGAF00002197691 fastq.gz 2.1 GB
EGAF00002197692 fastq.gz 2.9 GB
EGAF00002197693 fastq.gz 3.4 GB
EGAF00002197694 fastq.gz 2.8 GB
EGAF00002197695 fastq.gz 3.2 GB
EGAF00002197696 fastq.gz 1.6 GB
EGAF00002197697 fastq.gz 1.9 GB
EGAF00002197698 fastq.gz 1.5 GB
EGAF00002197699 fastq.gz 1.8 GB
EGAF00002197700 fastq.gz 1.5 GB
EGAF00002197701 fastq.gz 1.8 GB
EGAF00002197702 fastq.gz 1.5 GB
EGAF00002197703 fastq.gz 1.8 GB
EGAF00002197704 fastq.gz 1.3 GB
EGAF00002197705 fastq.gz 1.4 GB
EGAF00002197706 fastq.gz 2.0 GB
EGAF00002197707 fastq.gz 2.2 GB
EGAF00002197708 fastq.gz 1.9 GB
EGAF00002197709 fastq.gz 2.1 GB
EGAF00002197710 fastq.gz 2.0 GB
EGAF00002197711 fastq.gz 2.3 GB
EGAF00002197712 fastq.gz 5.4 GB
EGAF00002197713 fastq.gz 6.0 GB
EGAF00002197714 fastq.gz 6.9 GB
EGAF00002197715 fastq.gz 8.0 GB
EGAF00002197716 fastq.gz 2.7 GB
EGAF00002197717 fastq.gz 2.9 GB
EGAF00002197718 fastq.gz 2.2 GB
EGAF00002197719 fastq.gz 2.5 GB
EGAF00002197720 fastq.gz 5.4 GB
EGAF00002197721 fastq.gz 6.1 GB
EGAF00002197722 fastq.gz 5.0 GB
EGAF00002197723 fastq.gz 5.5 GB
EGAF00002197724 fastq.gz 4.7 GB
EGAF00002197725 fastq.gz 4.9 GB
EGAF00002197726 fastq.gz 2.4 GB
EGAF00002197727 fastq.gz 2.6 GB
EGAF00002197728 fastq.gz 5.3 GB
EGAF00002197729 fastq.gz 5.9 GB
EGAF00002197730 fastq.gz 4.8 GB
EGAF00002197731 fastq.gz 5.3 GB
EGAF00002197732 fastq.gz 4.5 GB
EGAF00002197733 fastq.gz 4.7 GB
EGAF00002197734 fastq.gz 2.5 GB
EGAF00002197735 fastq.gz 2.6 GB
EGAF00002197736 fastq.gz 7.5 GB
EGAF00002197737 fastq.gz 8.2 GB
EGAF00002197738 fastq.gz 9.0 GB
EGAF00002197739 fastq.gz 9.7 GB
EGAF00002197740 fastq.gz 9.9 GB
EGAF00002197741 fastq.gz 11.2 GB
EGAF00002197742 fastq.gz 7.5 GB
EGAF00002197743 fastq.gz 8.0 GB
EGAF00002197744 fastq.gz 11.6 GB
EGAF00002197745 fastq.gz 12.7 GB
EGAF00002197746 fastq.gz 6.9 GB
EGAF00002197747 fastq.gz 7.6 GB
EGAF00002197748 fastq.gz 8.4 GB
EGAF00002197749 fastq.gz 9.0 GB
EGAF00002197750 fastq.gz 9.2 GB
EGAF00002197751 fastq.gz 10.5 GB
EGAF00002197752 fastq.gz 7.0 GB
EGAF00002197753 fastq.gz 7.5 GB
EGAF00002197754 fastq.gz 10.9 GB
EGAF00002197755 fastq.gz 11.9 GB
EGAF00002197756 fastq.gz 7.5 GB
EGAF00002197757 fastq.gz 7.8 GB
EGAF00002197758 fastq.gz 5.7 GB
EGAF00002197759 fastq.gz 5.9 GB
EGAF00002197760 fastq.gz 3.5 GB
EGAF00002197761 fastq.gz 3.7 GB
EGAF00002197762 fastq.gz 7.8 GB
EGAF00002197763 fastq.gz 8.3 GB
EGAF00002197764 fastq.gz 6.0 GB
EGAF00002197765 fastq.gz 6.4 GB
EGAF00002197766 fastq.gz 3.8 GB
EGAF00002197767 fastq.gz 4.1 GB
EGAF00002197768 fastq.gz 3.1 GB
EGAF00002197769 fastq.gz 3.7 GB
EGAF00002197770 fastq.gz 2.7 GB
EGAF00002197771 fastq.gz 3.2 GB
EGAF00002197772 fastq.gz 2.5 GB
EGAF00002197773 fastq.gz 3.0 GB
EGAF00002197774 fastq.gz 3.3 GB
EGAF00002197775 fastq.gz 4.0 GB
EGAF00002197776 fastq.gz 3.0 GB
EGAF00002197777 fastq.gz 3.6 GB
EGAF00002197778 fastq.gz 3.8 GB
EGAF00002197779 fastq.gz 4.6 GB
214 Files (743.7 GB)