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IVAC Melanoma

Whole exome and transcriptome sequencing of 12 melanoma patients (including technical replicates). linicalTrials.gov Identifier: NCT02035956. Paper: Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer - Nature volume 547, pages 222–226

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IVAC melanoma data access policy

DATA ACCESS AGREEMENT This Data Access Agreement between Biontech AG, An der Goldgrube 12, 55131 Mainz and User Institution (as defined below) governs access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom Biontech AG grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: Biontech AG and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. You shall be free to publish the results of the research using the Data for the Project. You agree to acknowledge in any such publication that the research makes use of the Data generated by Biontech AG or its affiliates. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. You agree to use the Data in accordance with all applicable laws, including but not limited to European data privacy laws (General Data Protection Regulation, German Data Privacy Law). 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. You understand and acknowledge that the Data is protected by copyright and other intellectual property rights, and that duplication, except as reasonably required to carry out the Project with the Data, or sale of all or part of the Data on any media is not permitted. 7. You recognize that nothing in this Agreement shall operate to transfer to the User Organization any intellectual property rights relating to the Data. The User Organization has the right to develop intellectual property based on the comparison with their own Data. Any invention or discovery made by User and/or User Organization arising out of the Use of the Data shall be promptly disclosed to Biontech AG in writing. User Organization hereby grants to Biontech AG a royalty-free, fully paid, non-exclusive license (i) to make, use and import such invention for internal research purposes; and (ii) to make, use, offer to sell, sell and import such invention to the extent necessary to commercialize Biontech product(s) which license shall be sublicensable to Biontech´s affiliates and development and commercialization collaborators on such product(s). 8. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 11. The User Institution will notify Biontech AG within 30 days of any changes or departures of Authorised Personnel. 12. The User Institution will notify Biontech AG prior to any significant changes to the protocol for the Project. 13. The User Institution will notify Biontech AG as soon as it becomes aware of a breach of the terms or conditions of this agreement. 14. Biontech AG may terminate this agreement for any reason by written notice to the User Institution. If this agreement terminates, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 15. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than Biontech AG. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 16. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 17. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 18. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of England and Wales and shall be subject to the exclusive jurisdiction of the English courts.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002235806 fastq.gz 5.9 GB
EGAF00002235807 fastq.gz 5.8 GB
EGAF00002235808 fastq.gz 4.3 GB
EGAF00002235809 fastq.gz 4.3 GB
EGAF00002235810 fastq.gz 6.1 GB
EGAF00002235811 fastq.gz 6.1 GB
EGAF00002235812 fastq.gz 5.5 GB
EGAF00002235813 fastq.gz 5.5 GB
EGAF00002235814 fastq.gz 6.6 GB
EGAF00002235815 fastq.gz 6.6 GB
EGAF00002235816 fastq.gz 5.8 GB
EGAF00002235817 fastq.gz 5.9 GB
EGAF00002235818 fastq.gz 5.5 GB
EGAF00002235819 fastq.gz 5.6 GB
EGAF00002235820 fastq.gz 5.0 GB
EGAF00002235821 fastq.gz 5.0 GB
EGAF00002235822 fastq.gz 5.2 GB
EGAF00002235823 fastq.gz 5.2 GB
EGAF00002235824 fastq.gz 6.3 GB
EGAF00002235825 fastq.gz 6.3 GB
EGAF00002235826 fastq.gz 5.6 GB
EGAF00002235827 fastq.gz 5.6 GB
EGAF00002235828 fastq.gz 5.5 GB
EGAF00002235829 fastq.gz 5.5 GB
EGAF00002235830 fastq.gz 5.2 GB
EGAF00002235831 fastq.gz 5.2 GB
EGAF00002235832 fastq.gz 5.2 GB
EGAF00002235833 fastq.gz 5.2 GB
EGAF00002235834 fastq.gz 5.5 GB
EGAF00002235835 fastq.gz 5.5 GB
EGAF00002235836 fastq.gz 5.9 GB
EGAF00002235837 fastq.gz 5.9 GB
EGAF00002235838 fastq.gz 5.4 GB
EGAF00002235839 fastq.gz 5.4 GB
EGAF00002235840 fastq.gz 10.1 GB
EGAF00002235841 fastq.gz 10.1 GB
EGAF00002235842 fastq.gz 9.8 GB
EGAF00002235843 fastq.gz 9.8 GB
EGAF00002235844 fastq.gz 10.4 GB
EGAF00002235845 fastq.gz 10.6 GB
EGAF00002235846 fastq.gz 11.1 GB
EGAF00002235847 fastq.gz 11.3 GB
EGAF00002235848 fastq.gz 10.8 GB
EGAF00002235849 fastq.gz 11.0 GB
EGAF00002235850 fastq.gz 10.1 GB
EGAF00002235851 fastq.gz 10.3 GB
EGAF00002235852 fastq.gz 9.1 GB
EGAF00002235853 fastq.gz 9.3 GB
EGAF00002235854 fastq.gz 8.8 GB
EGAF00002235855 fastq.gz 9.0 GB
EGAF00002235856 fastq.gz 7.9 GB
EGAF00002235857 fastq.gz 8.1 GB
EGAF00002235858 fastq.gz 7.6 GB
EGAF00002235859 fastq.gz 7.8 GB
EGAF00002235860 fastq.gz 10.7 GB
EGAF00002235861 fastq.gz 10.6 GB
EGAF00002235862 fastq.gz 11.0 GB
EGAF00002235863 fastq.gz 11.0 GB
EGAF00002235864 fastq.gz 8.5 GB
EGAF00002235865 fastq.gz 8.4 GB
EGAF00002235866 fastq.gz 9.8 GB
EGAF00002235867 fastq.gz 9.7 GB
EGAF00002235868 fastq.gz 10.4 GB
EGAF00002235869 fastq.gz 10.6 GB
EGAF00002235870 fastq.gz 10.0 GB
EGAF00002235871 fastq.gz 10.2 GB
EGAF00002235872 fastq.gz 7.3 GB
EGAF00002235873 fastq.gz 7.5 GB
EGAF00002235874 fastq.gz 9.0 GB
EGAF00002235875 fastq.gz 9.2 GB
EGAF00002235876 fastq.gz 11.1 GB
EGAF00002235877 fastq.gz 11.2 GB
EGAF00002235878 fastq.gz 11.0 GB
EGAF00002235879 fastq.gz 11.0 GB
EGAF00002235880 fastq.gz 10.9 GB
EGAF00002235881 fastq.gz 11.0 GB
EGAF00002235882 fastq.gz 10.5 GB
EGAF00002235883 fastq.gz 10.6 GB
EGAF00002235884 fastq.gz 10.9 GB
EGAF00002235885 fastq.gz 11.0 GB
EGAF00002235886 fastq.gz 10.6 GB
EGAF00002235887 fastq.gz 10.7 GB
EGAF00002235888 fastq.gz 9.4 GB
EGAF00002235889 fastq.gz 9.5 GB
EGAF00002235890 fastq.gz 9.8 GB
EGAF00002235891 fastq.gz 9.9 GB
EGAF00002235892 fastq.gz 10.1 GB
EGAF00002235893 fastq.gz 10.1 GB
EGAF00002235894 fastq.gz 11.8 GB
EGAF00002235895 fastq.gz 11.8 GB
EGAF00002235896 fastq.gz 8.5 GB
EGAF00002235897 fastq.gz 8.5 GB
EGAF00002235898 fastq.gz 8.8 GB
EGAF00002235899 fastq.gz 8.8 GB
EGAF00002235900 fastq.gz 11.3 GB
EGAF00002235901 fastq.gz 11.4 GB
EGAF00002235902 fastq.gz 11.3 GB
EGAF00002235903 fastq.gz 11.4 GB
EGAF00002235904 fastq.gz 8.7 GB
EGAF00002235905 fastq.gz 8.6 GB
EGAF00002235906 fastq.gz 10.0 GB
EGAF00002235907 fastq.gz 10.1 GB
EGAF00002235908 fastq.gz 11.7 GB
EGAF00002235909 fastq.gz 11.7 GB
EGAF00002235910 fastq.gz 12.6 GB
EGAF00002235911 fastq.gz 12.6 GB
EGAF00002235912 fastq.gz 12.6 GB
EGAF00002235913 fastq.gz 12.6 GB
EGAF00002235914 fastq.gz 10.6 GB
EGAF00002235915 fastq.gz 10.6 GB
EGAF00002235916 fastq.gz 10.5 GB
EGAF00002235917 fastq.gz 10.5 GB
EGAF00002235918 fastq.gz 11.0 GB
EGAF00002235919 fastq.gz 10.9 GB
EGAF00002235920 fastq.gz 7.5 GB
EGAF00002235921 fastq.gz 7.5 GB
EGAF00002235922 fastq.gz 9.6 GB
EGAF00002235923 fastq.gz 9.6 GB
EGAF00002235924 fastq.gz 9.8 GB
EGAF00002235925 fastq.gz 9.9 GB
EGAF00002235926 fastq.gz 10.0 GB
EGAF00002235927 fastq.gz 10.0 GB
EGAF00002235928 fastq.gz 11.3 GB
EGAF00002235929 fastq.gz 11.4 GB
EGAF00002235930 fastq.gz 9.9 GB
EGAF00002235931 fastq.gz 10.0 GB
EGAF00002235932 fastq.gz 10.9 GB
EGAF00002235933 fastq.gz 10.9 GB
EGAF00002235934 fastq.gz 8.7 GB
EGAF00002235935 fastq.gz 8.7 GB
EGAF00002235936 fastq.gz 8.3 GB
EGAF00002235937 fastq.gz 7.8 GB
EGAF00002235938 fastq.gz 7.1 GB
EGAF00002235939 fastq.gz 6.7 GB
EGAF00002235940 fastq.gz 5.8 GB
EGAF00002235941 fastq.gz 5.9 GB
EGAF00002235942 fastq.gz 5.6 GB
EGAF00002235943 fastq.gz 5.7 GB
EGAF00002235944 fastq.gz 6.8 GB
EGAF00002235945 fastq.gz 6.9 GB
EGAF00002235946 fastq.gz 5.0 GB
EGAF00002235947 fastq.gz 5.0 GB
EGAF00002235948 fastq.gz 6.1 GB
EGAF00002235949 fastq.gz 6.0 GB
144 Files (1.2 TB)