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EPITREAT extended cohort

Data set of 22 tumor/normal pairs of non-small cell lung cancer (NSCLC) patients. All tissue pairs were screened with MeDIP methylation enrichment sequencing and validations were performed with targeted bisulfite re-sequencing.

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EPITREAT complete data set containing non-small cell lung cancer (NSCLC) methylation data.

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom EDPC grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: EDPC and the collaborators listed in Appendix I responsible for the development, organisation, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. EDPC: Epitreat data production consortium (EDPC) 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. In particular, the User Institution agrees not to publish any raw data sequences which may be used for an identification of the Research Participant. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Kodex für nicht-ärztliche Wissenschaftler, die an der Totalsequenzierung, insbesondere von Patientengenomen, beteiligt sind (https://www.dkfz.de/de/mga/download/Pressemeldungen/mk_eurat_stellungnahme.pdf?m=1421890866), the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognizing the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analyzing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organization for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify EDPC within 30 days of any changes or departures of Authorized Personnel. 13. The User Institution will notify EDPC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify EDPC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. EDPC may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. As an example, this may include specific provisions relating to the Data required by Data Producers other than EDPC. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorized Personnel. The User Institution will procure that the Authorized Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of Germany and shall be subject to the exclusive jurisdiction of the German courts.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00001685382 fastq.gz 2.2 GB
EGAF00001685383 fastq.gz 2.2 GB
EGAF00001685384 fastq.gz 1.5 GB
EGAF00001685385 fastq.gz 1.5 GB
EGAF00001685386 fastq.gz 1.0 GB
EGAF00001685387 fastq.gz 1.1 GB
EGAF00001685388 fastq.gz 2.5 GB
EGAF00001685389 fastq.gz 2.6 GB
EGAF00001685390 fastq.gz 1.5 GB
EGAF00001685391 fastq.gz 1.5 GB
EGAF00001685392 fastq.gz 1.2 GB
EGAF00001685393 fastq.gz 1.3 GB
EGAF00001685394 fastq.gz 681.2 MB
EGAF00001685395 fastq.gz 700.8 MB
EGAF00001685396 fastq.gz 965.3 MB
EGAF00001685397 fastq.gz 995.4 MB
EGAF00001685398 fastq.gz 598.5 MB
EGAF00001685399 fastq.gz 610.9 MB
EGAF00001685400 fastq.gz 1.0 GB
EGAF00001685401 fastq.gz 1.1 GB
EGAF00001685402 fastq.gz 689.1 MB
EGAF00001685403 fastq.gz 708.7 MB
EGAF00001685404 fastq.gz 1.0 GB
EGAF00001685405 fastq.gz 1.1 GB
EGAF00001685406 fastq.gz 2.3 GB
EGAF00001685407 fastq.gz 2.4 GB
EGAF00001685408 fastq.gz 659.0 MB
EGAF00001685409 fastq.gz 676.0 MB
EGAF00001685410 fastq.gz 1.2 GB
EGAF00001685411 fastq.gz 1.2 GB
EGAF00001685412 fastq.gz 2.4 GB
EGAF00001685413 fastq.gz 2.4 GB
EGAF00001685414 fastq.gz 2.5 GB
EGAF00001685415 fastq.gz 2.6 GB
EGAF00001685416 fastq.gz 2.7 GB
EGAF00001685417 fastq.gz 2.7 GB
EGAF00001685418 fastq.gz 2.0 GB
EGAF00001685419 fastq.gz 2.1 GB
EGAF00001685420 fastq.gz 2.6 GB
EGAF00001685421 fastq.gz 2.6 GB
EGAF00001685422 fastq.gz 2.8 GB
EGAF00001685423 fastq.gz 2.9 GB
EGAF00001685424 fastq.gz 2.4 GB
EGAF00001685425 fastq.gz 2.4 GB
EGAF00001685426 fastq.gz 2.6 GB
EGAF00001685427 fastq.gz 2.7 GB
EGAF00001685428 fastq.gz 3.0 GB
EGAF00001685429 fastq.gz 3.1 GB
EGAF00001685430 fastq.gz 2.1 GB
EGAF00001685431 fastq.gz 2.2 GB
EGAF00001685432 fastq.gz 2.3 GB
EGAF00001685433 fastq.gz 2.4 GB
EGAF00001685434 fastq.gz 1.9 GB
EGAF00001685435 fastq.gz 2.0 GB
EGAF00001685436 fastq.gz 2.3 GB
EGAF00001685437 fastq.gz 2.4 GB
EGAF00001685438 fastq.gz 1.9 GB
EGAF00001685439 fastq.gz 1.9 GB
EGAF00001685440 fastq.gz 3.3 GB
EGAF00001685441 fastq.gz 3.4 GB
EGAF00001685442 fastq.gz 3.0 GB
EGAF00001685443 fastq.gz 3.1 GB
EGAF00001685444 fastq.gz 1.4 GB
EGAF00001685445 fastq.gz 1.5 GB
EGAF00001685446 fastq.gz 1.5 GB
EGAF00001685447 fastq.gz 1.5 GB
EGAF00001685448 fastq.gz 1.2 GB
EGAF00001685449 fastq.gz 1.3 GB
EGAF00001685450 fastq.gz 2.0 GB
EGAF00001685451 fastq.gz 2.0 GB
EGAF00001685452 fastq.gz 2.1 GB
EGAF00001685453 fastq.gz 2.1 GB
EGAF00001685454 fastq.gz 2.1 GB
EGAF00001685455 fastq.gz 2.2 GB
EGAF00001685456 fastq.gz 1.8 GB
EGAF00001685457 fastq.gz 1.8 GB
EGAF00001685458 fastq.gz 2.2 GB
EGAF00001685459 fastq.gz 2.2 GB
EGAF00001685460 fastq.gz 1.9 GB
EGAF00001685461 fastq.gz 2.0 GB
EGAF00001685462 fastq.gz 2.4 GB
EGAF00001685463 fastq.gz 2.4 GB
EGAF00001685464 fastq.gz 2.1 GB
EGAF00001685465 fastq.gz 2.1 GB
EGAF00001685466 fastq.gz 2.5 GB
EGAF00001685467 fastq.gz 2.5 GB
EGAF00001685468 fastq.gz 1.8 GB
EGAF00001685469 fastq.gz 1.9 GB
EGAF00001685470 fastq.gz 2.5 GB
EGAF00001685471 fastq.gz 2.5 GB
EGAF00001685472 fastq.gz 1.8 GB
EGAF00001685473 fastq.gz 1.8 GB
EGAF00001685474 fastq.gz 1.9 GB
EGAF00001685475 fastq.gz 2.0 GB
EGAF00001685476 fastq.gz 1.8 GB
EGAF00001685477 fastq.gz 1.8 GB
EGAF00001685478 fastq.gz 1.8 GB
EGAF00001685479 fastq.gz 1.8 GB
EGAF00001685480 fastq.gz 2.5 GB
EGAF00001685481 fastq.gz 2.6 GB
EGAF00001685482 fastq.gz 1.4 GB
EGAF00001685483 fastq.gz 1.5 GB
EGAF00001685484 fastq.gz 2.9 GB
EGAF00001685485 fastq.gz 3.0 GB
EGAF00001685486 fastq.gz 3.3 GB
EGAF00001685487 fastq.gz 3.4 GB
EGAF00001685488 fastq.gz 2.0 GB
EGAF00001685489 fastq.gz 2.1 GB
EGAF00001685490 fastq.gz 1.6 GB
EGAF00001685491 fastq.gz 1.7 GB
EGAF00001685492 fastq.gz 2.4 GB
EGAF00001685493 fastq.gz 2.5 GB
EGAF00001685809 fastq.gz 2.2 GB
EGAF00001685810 fastq.gz 2.0 GB
EGAF00001685811 fastq.gz 2.4 GB
EGAF00001685812 fastq.gz 2.2 GB
EGAF00001685813 fastq.gz 2.2 GB
EGAF00001685814 fastq.gz 2.1 GB
EGAF00001685815 fastq.gz 2.3 GB
EGAF00001685816 fastq.gz 2.1 GB
EGAF00001685817 fastq.gz 2.3 GB
EGAF00001685818 fastq.gz 2.1 GB
EGAF00001685819 fastq.gz 2.1 GB
EGAF00001685820 fastq.gz 2.0 GB
EGAF00001685821 fastq.gz 932.0 MB
EGAF00001685822 fastq.gz 823.9 MB
EGAF00001685823 fastq.gz 943.5 MB
EGAF00001685824 fastq.gz 834.4 MB
EGAF00001685825 fastq.gz 954.6 MB
EGAF00001685826 fastq.gz 840.0 MB
EGAF00001685827 fastq.gz 1.2 GB
EGAF00001685828 fastq.gz 1.1 GB
EGAF00001685829 fastq.gz 1.0 GB
EGAF00001685830 fastq.gz 915.7 MB
EGAF00001685831 fastq.gz 1.4 GB
EGAF00001685832 fastq.gz 1.3 GB
EGAF00001685833 fastq.gz 1.2 GB
EGAF00001685834 fastq.gz 1.0 GB
EGAF00001685835 fastq.gz 885.1 MB
EGAF00001685836 fastq.gz 792.4 MB
140 Files (264.8 GB)