Homologous recombination deficient breast cancers

Breast cancer DNA repair policy

Breast cancer DNA repair policy includes the controlled public distribution of exome sequencing data of primary breast cancers with defects in DNA repair pathways Access to this data will be controlled by the DAC. Access to data is permitted after submission of a research question, which will be evaluated by the DAC main contact. The data can only be used for this particular research question. In the event of publication, the original publication of this data must be properly referenced (Functional ex vivo assay reveals homologous recombination deficiency in breast cancer beyond BRCA gene defects, Titia G. Meijer, Nicole S. Verkaik, Anieta M. Sieuwerts, Job van Riet, Kishan A.T. Naipal, Carolien H.M. van Deurzen, Michael A. den Bakker, Hein F.B.M. Sleddens, Hendrikus-Jan Dubbink, T. Dorine den Toom, Winand N.M. Dinjens, Esther Lips, Petra M. Nederlof, Marcel Smid, Harmen J. G. van de Werken, Roland Kanaar, John W. M. Martens, Agnes Jager and Dik C. van Gent, Clin Cancer Res. 2018 Aug 23. pii: clincanres.0063.2018. doi: 10.1158/1078-0432.CCR-18-0063. [Epub ahead of print]) as well as co-authorship of the DAC main contact must be guaranteed.