Amplicon-based sequencing of drug resistant lung cancer cell lines (2017-07-05)
A EGFR mutant NSCLC cell line which is sensitive to AZD9291 inhibition was mutagenised with the chemical mutagen ENU and then drug selected using a AZD9291. Single cell derived colonies were then manually picked and expanded in drug. Resistance was confirmed in a 14 day assay and DNA was collected. These then underwent targeted amplicon-based sequencing to confirm candidate resistance effectors hypothesised from currently available literature. This dataset contains all the data available for this study on 2017-07-05.
- 12/07/2017
- 177 samples
- DAC: EGAC00001000000
- Technology: Illumina MiSeq
- PUB DUO:0000019 (version: 2021-02-23)publication requiredThis data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community.
- US DUO:0000026 (version: 2021-02-23)user specific restrictionThis data use modifier indicates that use is limited to use by approved users.
- IS DUO:0000028 (version: 2021-02-23)institution specific restrictionThis data use modifier indicates that use is limited to use within an approved institution.
- GRU DUO:0000042 (version: 2021-02-23)general research useThis data use permission indicates that use is allowed for general research use for any research purpose.
Wellcome Trust Sanger Institute Cancer Genome Group Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| Cancer Genomics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00001305538 | cram | 9.9 MB | ||
| EGAF00001305539 | cram | 10.3 MB | ||
| EGAF00001305540 | cram | 10.5 MB | ||
| EGAF00001305541 | cram | 10.7 MB | ||
| EGAF00001305542 | cram | 12.0 MB | ||
| EGAF00001305543 | cram | 5.1 MB | ||
| EGAF00001305544 | cram | 2.5 MB | ||
| EGAF00001305545 | cram | 17.6 MB | ||
| EGAF00001305546 | cram | 1.9 MB | ||
| EGAF00001305547 | cram | 7.8 MB | ||
| EGAF00001305548 | cram | 3.0 MB | ||
| EGAF00001305549 | cram | 12.0 MB | ||
| EGAF00001305550 | cram | 7.2 MB | ||
| EGAF00001305551 | cram | 11.5 MB | ||
| EGAF00001305552 | cram | 7.3 MB | ||
| EGAF00001305553 | cram | 2.7 MB | ||
| EGAF00001305554 | cram | 13.4 MB | ||
| EGAF00001305555 | cram | 11.0 MB | ||
| EGAF00001305556 | cram | 7.7 MB | ||
| EGAF00001305557 | cram | 11.3 MB | ||
| EGAF00001305558 | cram | 2.6 MB | ||
| EGAF00001305559 | cram | 7.4 MB | ||
| EGAF00001305560 | cram | 8.2 MB | ||
| EGAF00001305561 | cram | 11.9 MB | ||
| EGAF00001305562 | cram | 7.8 MB | ||
| EGAF00001306435 | cram | 9.3 MB | ||
| EGAF00001306436 | cram | 6.0 MB | ||
| EGAF00001306437 | cram | 14.4 MB | ||
| EGAF00001306438 | cram | 7.6 MB | ||
| EGAF00001306439 | cram | 7.7 MB | ||
| EGAF00001306440 | cram | 9.2 MB | ||
| EGAF00001306441 | cram | 7.4 MB | ||
| EGAF00001306442 | cram | 11.1 MB | ||
| EGAF00001306443 | cram | 15.1 MB | ||
| EGAF00001306444 | cram | 3.5 MB | ||
| EGAF00001306445 | cram | 15.1 MB | ||
| EGAF00001306446 | cram | 3.4 MB | ||
| EGAF00001306447 | cram | 10.5 MB | ||
| EGAF00001306448 | cram | 10.5 MB | ||
| EGAF00001306449 | cram | 11.2 MB | ||
| EGAF00001306450 | cram | 6.0 MB | ||
| EGAF00001306451 | cram | 2.8 MB | ||
| EGAF00001306452 | cram | 3.9 MB | ||
| EGAF00001306453 | cram | 3.2 MB | ||
| EGAF00001306454 | cram | 3.3 MB | ||
| EGAF00001306455 | cram | 3.7 MB | ||
| EGAF00001306456 | cram | 4.2 MB | ||
| EGAF00001306457 | cram | 6.8 MB | ||
| EGAF00001306458 | cram | 4.4 MB | ||
| EGAF00001306459 | cram | 4.1 MB | ||
| EGAF00001306460 | cram | 4.2 MB | ||
| EGAF00001306461 | cram | 3.6 MB | ||
| EGAF00001306462 | cram | 3.8 MB | ||
| EGAF00001306463 | cram | 4.0 MB | ||
| EGAF00001306464 | cram | 4.0 MB | ||
| EGAF00001306465 | cram | 3.1 MB | ||
| EGAF00001306466 | cram | 3.5 MB | ||
| EGAF00001306467 | cram | 4.4 MB | ||
| EGAF00001306468 | cram | 2.7 MB | ||
| EGAF00001306469 | cram | 4.2 MB | ||
| EGAF00001306470 | cram | 3.7 MB | ||
| EGAF00001306471 | cram | 4.4 MB | ||
| EGAF00001306472 | cram | 3.6 MB | ||
| EGAF00001306473 | cram | 2.7 MB | ||
| EGAF00001306474 | cram | 991.3 kB | ||
| EGAF00001306475 | cram | 2.9 MB | ||
| EGAF00001306476 | cram | 3.5 MB | ||
| EGAF00001306477 | cram | 4.6 MB | ||
| EGAF00001306478 | cram | 2.4 MB | ||
| EGAF00001306479 | cram | 3.0 MB | ||
| EGAF00001306480 | cram | 3.0 MB | ||
| EGAF00001306481 | cram | 3.0 MB | ||
| EGAF00001306482 | cram | 4.3 MB | ||
| EGAF00001306483 | cram | 4.1 MB | ||
| EGAF00001306484 | cram | 4.7 MB | ||
| EGAF00001306485 | cram | 5.7 MB | ||
| EGAF00001306486 | cram | 3.9 MB | ||
| EGAF00001306487 | cram | 3.4 MB | ||
| EGAF00001306488 | cram | 4.8 MB | ||
| EGAF00001306489 | cram | 4.2 MB | ||
| EGAF00001306490 | cram | 5.5 MB | ||
| EGAF00001306491 | cram | 3.8 MB | ||
| EGAF00001306492 | cram | 3.3 MB | ||
| EGAF00001306493 | cram | 4.9 MB | ||
| EGAF00001306494 | cram | 3.9 MB | ||
| EGAF00001306495 | cram | 3.7 MB | ||
| EGAF00001306496 | cram | 4.6 MB | ||
| EGAF00001306497 | cram | 4.9 MB | ||
| EGAF00001306498 | cram | 6.0 MB | ||
| EGAF00001306499 | cram | 598.2 kB | ||
| EGAF00001306500 | cram | 4.4 MB | ||
| EGAF00001306501 | cram | 4.5 MB | ||
| EGAF00001306502 | cram | 6.1 MB | ||
| EGAF00001306503 | cram | 8.2 MB | ||
| EGAF00001306504 | cram | 6.2 MB | ||
| EGAF00001306505 | cram | 4.4 MB | ||
| EGAF00001306506 | cram | 22.4 MB | ||
| EGAF00001306507 | cram | 5.3 MB | ||
| EGAF00001306508 | cram | 3.0 MB | ||
| EGAF00001306509 | cram | 2.1 MB | ||
| EGAF00001306510 | cram | 3.6 MB | ||
| EGAF00001306511 | cram | 2.8 MB | ||
| EGAF00001306512 | cram | 5.7 MB | ||
| EGAF00001306513 | cram | 12.2 MB | ||
| EGAF00001306514 | cram | 564.3 kB | ||
| EGAF00001306515 | cram | 1.7 MB | ||
| EGAF00001306516 | cram | 10.3 MB | ||
| EGAF00001306517 | cram | 4.2 MB | ||
| EGAF00001306518 | cram | 1.2 MB | ||
| EGAF00001306519 | cram | 2.0 MB | ||
| EGAF00001306520 | cram | 3.0 MB | ||
| EGAF00001306521 | cram | 21.0 MB | ||
| EGAF00001306522 | cram | 4.2 MB | ||
| EGAF00001306523 | cram | 18.1 MB | ||
| EGAF00001306524 | cram | 6.8 MB | ||
| EGAF00001306525 | cram | 7.2 MB | ||
| EGAF00001306526 | cram | 688.7 kB | ||
| EGAF00001306527 | cram | 14.9 MB | ||
| EGAF00001306528 | cram | 14.9 MB | ||
| EGAF00001307313 | cram | 12.2 MB | ||
| EGAF00001307314 | cram | 23.4 MB | ||
| EGAF00001307315 | cram | 15.7 MB | ||
| EGAF00001307316 | cram | 4.5 MB | ||
| EGAF00001307317 | cram | 11.4 MB | ||
| EGAF00001307318 | cram | 11.6 MB | ||
| EGAF00001307319 | cram | 2.1 MB | ||
| EGAF00001307320 | cram | 8.1 MB | ||
| EGAF00001307321 | cram | 18.6 MB | ||
| EGAF00001307322 | cram | 18.6 MB | ||
| EGAF00001307323 | cram | 12.1 MB | ||
| EGAF00001307324 | cram | 2.6 MB | ||
| EGAF00001307325 | cram | 9.9 MB | ||
| EGAF00001307326 | cram | 10.9 MB | ||
| EGAF00001307327 | cram | 22.2 MB | ||
| EGAF00001307328 | cram | 8.3 MB | ||
| EGAF00001307329 | cram | 3.5 MB | ||
| EGAF00001307330 | cram | 22.4 MB | ||
| EGAF00001307331 | cram | 7.4 MB | ||
| EGAF00001307332 | cram | 6.3 MB | ||
| EGAF00001307333 | cram | 884.3 kB | ||
| EGAF00001307334 | cram | 2.2 MB | ||
| EGAF00001307335 | cram | 4.1 MB | ||
| EGAF00001307336 | cram | 3.4 MB | ||
| EGAF00001307337 | cram | 4.0 MB | ||
| EGAF00001307338 | cram | 7.4 MB | ||
| EGAF00001307339 | cram | 2.6 MB | ||
| EGAF00001307340 | cram | 3.9 MB | ||
| EGAF00001307341 | cram | 3.3 MB | ||
| EGAF00001307342 | cram | 3.2 MB | ||
| EGAF00001307343 | cram | 3.4 MB | ||
| EGAF00001307344 | cram | 6.5 MB | ||
| EGAF00001307345 | cram | 7.9 MB | ||
| EGAF00001307346 | cram | 7.8 MB | ||
| EGAF00001307347 | cram | 3.3 MB | ||
| EGAF00001307348 | cram | 4.4 MB | ||
| EGAF00001307349 | cram | 3.5 MB | ||
| EGAF00001307350 | cram | 2.3 MB | ||
| EGAF00001307351 | cram | 3.2 MB | ||
| EGAF00001307352 | cram | 813.7 kB | ||
| EGAF00001307353 | cram | 20.2 MB | ||
| EGAF00001307354 | cram | 4.5 MB | ||
| EGAF00001307355 | cram | 2.1 MB | ||
| EGAF00001307356 | cram | 2.1 MB | ||
| EGAF00001307357 | cram | 2.7 MB | ||
| EGAF00001307358 | cram | 2.6 MB | ||
| EGAF00001307359 | cram | 4.0 MB | ||
| EGAF00001307360 | cram | 2.5 MB | ||
| EGAF00001307361 | cram | 4.4 MB | ||
| EGAF00001307362 | cram | 4.8 MB | ||
| EGAF00001307363 | cram | 8.1 MB | ||
| EGAF00001307364 | cram | 3.4 MB | ||
| EGAF00001307365 | cram | 3.7 MB | ||
| EGAF00001307366 | cram | 8.4 MB | ||
| EGAF00001307367 | cram | 4.1 MB | ||
| EGAF00001590352 | cram | 32.5 MB | ||
| EGAF00001590353 | cram | 18.6 MB | ||
| EGAF00001590354 | cram | 5.0 MB | ||
| 177 Files (1.2 GB) | ||||