Clonal expansion of mutated cell population in bladder urothelium
1cm biospies of from patients undergoing bladder cystectomy will be collected. The underlying muscle and stroma will be removed and the remaining epithelia dissected into small sequential areas which will be sent for ultra-deep exome sequencing using a panel of known cancer and viral genes. Sequence analysis using similar methods to Martincorena I et al (Science 2015, 348:880) will provide an idea of the somatic mutational landscape in these patient samples. Individual patient muscle samples will also be sequenced as a reference.
- 27/03/2017
- 55 samples
- DAC: EGAC00001000205
- Technology: Illumina HiSeq 2000
Wellcome Trust Sanger Institute Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| Cancer Genomics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00001234506 | cram | 904.4 MB | ||
| EGAF00001234507 | cram | 845.7 MB | ||
| EGAF00001234508 | cram | 1.0 GB | ||
| EGAF00001234509 | cram | 1.0 GB | ||
| EGAF00001234510 | cram | 1.0 GB | ||
| EGAF00001234511 | cram | 1.0 GB | ||
| EGAF00001234512 | cram | 992.6 MB | ||
| EGAF00001234513 | cram | 895.6 MB | ||
| EGAF00001234514 | cram | 694.0 MB | ||
| EGAF00001234515 | cram | 670.1 MB | ||
| EGAF00001234516 | cram | 716.2 MB | ||
| EGAF00001234517 | cram | 777.2 MB | ||
| EGAF00001234518 | cram | 909.3 MB | ||
| EGAF00001234519 | cram | 937.9 MB | ||
| EGAF00001234520 | cram | 900.8 MB | ||
| EGAF00001234521 | cram | 705.5 MB | ||
| EGAF00001234522 | cram | 608.6 MB | ||
| EGAF00001234523 | cram | 610.7 MB | ||
| EGAF00001234524 | cram | 619.9 MB | ||
| EGAF00001234525 | cram | 678.9 MB | ||
| EGAF00001234526 | cram | 695.5 MB | ||
| EGAF00001234527 | cram | 648.6 MB | ||
| EGAF00001234528 | cram | 663.6 MB | ||
| EGAF00001234529 | cram | 637.7 MB | ||
| EGAF00001234530 | cram | 598.0 MB | ||
| EGAF00001234531 | cram | 571.7 MB | ||
| EGAF00001234532 | cram | 604.7 MB | ||
| EGAF00001234533 | cram | 633.1 MB | ||
| EGAF00001234534 | cram | 639.9 MB | ||
| EGAF00001234535 | cram | 959.3 MB | ||
| EGAF00001234536 | cram | 958.7 MB | ||
| EGAF00001234537 | cram | 943.2 MB | ||
| EGAF00001234538 | cram | 1.0 GB | ||
| EGAF00001234539 | cram | 873.0 MB | ||
| EGAF00001234540 | cram | 863.3 MB | ||
| EGAF00001234541 | cram | 965.3 MB | ||
| EGAF00001234542 | cram | 938.9 MB | ||
| EGAF00001234543 | cram | 831.5 MB | ||
| EGAF00001234544 | cram | 965.7 MB | ||
| EGAF00001234545 | cram | 862.1 MB | ||
| EGAF00001234546 | cram | 866.2 MB | ||
| EGAF00001234547 | cram | 873.3 MB | ||
| EGAF00001234548 | cram | 887.7 MB | ||
| EGAF00001234549 | cram | 981.8 MB | ||
| EGAF00001234550 | cram | 1.1 GB | ||
| EGAF00001234551 | cram | 871.6 MB | ||
| EGAF00001234552 | cram | 783.3 MB | ||
| EGAF00001234553 | cram | 850.5 MB | ||
| EGAF00001234554 | cram | 849.6 MB | ||
| EGAF00001234555 | cram | 828.3 MB | ||
| EGAF00001234556 | cram | 796.4 MB | ||
| EGAF00001234557 | cram | 904.9 MB | ||
| EGAF00001234558 | cram | 861.2 MB | ||
| EGAF00001234559 | cram | 856.8 MB | ||
| EGAF00001234560 | cram | 855.3 MB | ||
| 55 Files (45.5 GB) | ||||