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Precursor lesions, clonal architecture and relapse in Wilms nephroblastoma

Targeted resequencing at high depth (21 genes, 9 chromosomal regions): at least 4 FFPE samples per case and matched germline DNA: * 100 cases with detailed outcome data, including 15 cases with tumour relapse (515 samples) * 40 cases with matched pre-chemotherapy biopsies (240 samples) * 50 nephrogenic rests matched to above cases (50 samples) We expect a proportion (possibly 10%) of cases to be mutationally silent on the above studies, and propose to subsequently carry out integrated whole-genome, methylome and transcriptome studies on matched frozen tissue from these cases

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00001218595 cram 689.8 MB
EGAF00001218596 cram 775.7 MB
EGAF00001218597 cram 868.5 MB
EGAF00001218598 cram 698.2 MB
EGAF00001218599 cram 716.1 MB
EGAF00001218600 cram 759.0 MB
EGAF00001218601 cram 607.4 MB
EGAF00001218602 cram 654.4 MB
EGAF00001218603 cram 587.0 MB
EGAF00001218604 cram 560.2 MB
EGAF00001218605 cram 608.7 MB
EGAF00001218606 cram 715.2 MB
EGAF00001218607 cram 614.2 MB
EGAF00001218608 cram 754.7 MB
EGAF00001218609 cram 827.9 MB
EGAF00001218610 cram 591.2 MB
EGAF00001218611 cram 550.2 MB
EGAF00001218612 cram 638.4 MB
EGAF00001218613 cram 693.4 MB
EGAF00001218614 cram 779.8 MB
EGAF00001218615 cram 873.2 MB
EGAF00001218616 cram 701.8 MB
EGAF00001218617 cram 719.3 MB
EGAF00001218618 cram 762.7 MB
EGAF00001218619 cram 611.0 MB
EGAF00001218620 cram 658.2 MB
EGAF00001218621 cram 589.8 MB
EGAF00001218622 cram 563.8 MB
EGAF00001218623 cram 612.0 MB
EGAF00001218624 cram 719.0 MB
EGAF00001218625 cram 617.4 MB
EGAF00001218626 cram 758.6 MB
EGAF00001218627 cram 832.0 MB
EGAF00001218628 cram 594.2 MB
EGAF00001218629 cram 553.0 MB
EGAF00001218630 cram 642.0 MB
EGAF00001218631 cram 564.5 MB
EGAF00001218632 cram 538.0 MB
EGAF00001218633 cram 597.3 MB
EGAF00001218634 cram 579.3 MB
EGAF00001218635 cram 659.4 MB
EGAF00001218636 cram 922.0 MB
EGAF00001218637 cram 639.7 MB
EGAF00001218638 cram 643.2 MB
EGAF00001218639 cram 684.0 MB
EGAF00001218640 cram 624.0 MB
EGAF00001218641 cram 746.6 MB
EGAF00001218642 cram 682.4 MB
EGAF00001218643 cram 596.1 MB
EGAF00001218644 cram 695.1 MB
EGAF00001218645 cram 652.8 MB
EGAF00001218646 cram 638.3 MB
EGAF00001218647 cram 709.8 MB
EGAF00001218648 cram 552.8 MB
EGAF00001218649 cram 529.4 MB
EGAF00001218650 cram 586.3 MB
EGAF00001218651 cram 566.5 MB
EGAF00001218652 cram 644.9 MB
EGAF00001218653 cram 902.6 MB
EGAF00001218654 cram 625.2 MB
EGAF00001218655 cram 628.9 MB
EGAF00001218656 cram 670.4 MB
EGAF00001218657 cram 609.5 MB
EGAF00001218658 cram 729.6 MB
EGAF00001218659 cram 670.8 MB
EGAF00001218660 cram 585.0 MB
EGAF00001218661 cram 680.1 MB
EGAF00001218662 cram 639.9 MB
EGAF00001218663 cram 626.8 MB
EGAF00001218664 cram 697.1 MB
70 Files (46.6 GB)