Genomic Evolution of Breast Cancer Metastasis and Relapse
Recurrent breast cancer is almost universally fatal. We characterize 170 patients locally relapsed or distant metastatic cancers using massively parallel sequencing. We identify that the relapse-seeding clone disseminates late from the primary tumor. TP53 and AKT1 appear to be enriched in ER-positive cancers predisposed to relapse. Mutation acquisition continues at relapse as the same mutation signatures continue to operate and new signatures, such as that caused by radiotherapy appear de novo. In 49% of cases we identify drivers mutations private to the relapse and these are sampled from a wider range of cancer genes, including SWI-SNF complex and JAK-STAT signaling.
- 28/09/2016
- 387 samples
- DAC: EGAC00001000000
- Technologies: Illumina HiSeq 2000, Illumina HiSeq 2500, Illumina MiSeq
- PUB DUO:0000019 (version: 2021-02-23)publication requiredThis data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community.
- US DUO:0000026 (version: 2021-02-23)user specific restrictionThis data use modifier indicates that use is limited to use by approved users.
- IS DUO:0000028 (version: 2021-02-23)institution specific restrictionThis data use modifier indicates that use is limited to use within an approved institution.
- GRU DUO:0000042 (version: 2021-02-23)general research useThis data use permission indicates that use is allowed for general research use for any research purpose.
Wellcome Trust Sanger Institute Cancer Genome Group Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
Study ID | Study Title | Study Type |
---|---|---|
EGAS00001000596 | Cancer Genomics | |
EGAS00001000704 | Cancer Genomics | |
EGAS00001001968 | Cancer Genomics | |
EGAS00001001972 | Cancer Genomics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
ID | File Type | Size | Located in | |
---|---|---|---|---|
EGAF00000498157 | cram | 998.2 MB | ||
EGAF00000498158 | cram | 773.5 MB | ||
EGAF00000507238 | cram | 869.4 MB | ||
EGAF00000507239 | cram | 1.0 GB | ||
EGAF00000507240 | cram | 893.2 MB | ||
EGAF00000507241 | cram | 1.1 GB | ||
EGAF00000581817 | cram | 245.0 MB | ||
EGAF00000581818 | cram | 236.9 MB | ||
EGAF00000581819 | cram | 238.3 MB | ||
EGAF00000581820 | cram | 276.9 MB | ||
EGAF00000581821 | cram | 191.9 MB | ||
EGAF00000581822 | cram | 171.7 MB | ||
EGAF00000581823 | cram | 213.2 MB | ||
EGAF00000581824 | cram | 250.4 MB | ||
EGAF00000581825 | cram | 197.3 MB | ||
EGAF00000581826 | cram | 237.4 MB | ||
EGAF00000581827 | cram | 188.1 MB | ||
EGAF00000581829 | cram | 203.4 MB | ||
EGAF00000581830 | cram | 234.7 MB | ||
EGAF00000581833 | cram | 219.6 MB | ||
EGAF00000581834 | cram | 241.9 MB | ||
EGAF00000581835 | cram | 272.7 MB | ||
EGAF00000581836 | cram | 222.6 MB | ||
EGAF00000581837 | cram | 227.7 MB | ||
EGAF00000581838 | cram | 254.6 MB | ||
EGAF00000581839 | cram | 220.6 MB | ||
EGAF00000581840 | cram | 201.5 MB | ||
EGAF00000581841 | cram | 203.2 MB | ||
EGAF00000581842 | cram | 229.1 MB | ||
EGAF00000581843 | cram | 215.5 MB | ||
EGAF00000581844 | cram | 204.9 MB | ||
EGAF00000581845 | cram | 216.1 MB | ||
EGAF00000581846 | cram | 233.2 MB | ||
EGAF00000581847 | cram | 238.5 MB | ||
EGAF00000581848 | cram | 199.9 MB | ||
EGAF00000581849 | cram | 205.3 MB | ||
EGAF00000581851 | cram | 187.3 MB | ||
EGAF00000581852 | cram | 201.5 MB | ||
EGAF00000581853 | cram | 259.9 MB | ||
EGAF00000581854 | cram | 227.9 MB | ||
EGAF00000581855 | cram | 198.4 MB | ||
EGAF00000581856 | cram | 202.1 MB | ||
EGAF00000581857 | cram | 268.4 MB | ||
EGAF00000581858 | cram | 200.9 MB | ||
EGAF00000581860 | cram | 243.1 MB | ||
EGAF00000581861 | cram | 222.7 MB | ||
EGAF00000581862 | cram | 229.2 MB | ||
EGAF00000581863 | cram | 238.0 MB | ||
EGAF00000581864 | cram | 185.9 MB | ||
EGAF00000581865 | cram | 262.7 MB | ||
EGAF00000581866 | cram | 233.1 MB | ||
EGAF00000581867 | cram | 211.5 MB | ||
EGAF00000581868 | cram | 229.5 MB | ||
EGAF00000581869 | cram | 220.5 MB | ||
EGAF00000581870 | cram | 244.8 MB | ||
EGAF00000581871 | cram | 225.0 MB | ||
EGAF00000581872 | cram | 232.8 MB | ||
EGAF00000581873 | cram | 212.5 MB | ||
EGAF00000581874 | cram | 245.8 MB | ||
EGAF00000581875 | cram | 265.2 MB | ||
EGAF00000581876 | cram | 209.2 MB | ||
EGAF00000581877 | cram | 208.3 MB | ||
EGAF00000581878 | cram | 228.7 MB | ||
EGAF00000581879 | cram | 204.0 MB | ||
EGAF00000581882 | cram | 241.5 MB | ||
EGAF00000581883 | cram | 222.2 MB | ||
EGAF00000581884 | cram | 188.9 MB | ||
EGAF00000581886 | cram | 224.6 MB | ||
EGAF00000581887 | cram | 204.4 MB | ||
EGAF00000581888 | cram | 176.9 MB | ||
EGAF00000581889 | cram | 263.5 MB | ||
EGAF00000581890 | cram | 212.5 MB | ||
EGAF00000581891 | cram | 218.9 MB | ||
EGAF00000581892 | cram | 236.9 MB | ||
EGAF00000581895 | cram | 191.5 MB | ||
EGAF00000581896 | cram | 184.0 MB | ||
EGAF00000581897 | cram | 246.3 MB | ||
EGAF00000581898 | cram | 271.6 MB | ||
EGAF00000606664 | cram | 969.3 MB | ||
EGAF00000606666 | cram | 1.2 GB | ||
EGAF00000606667 | cram | 1.2 GB | ||
EGAF00000606668 | cram | 1.3 GB | ||
EGAF00000606670 | cram | 1.3 GB | ||
EGAF00000606672 | cram | 835.3 MB | ||
EGAF00000606673 | cram | 1.0 GB | ||
EGAF00000606674 | cram | 1.2 GB | ||
EGAF00000606675 | cram | 800.7 MB | ||
EGAF00000606677 | cram | 1.1 GB | ||
EGAF00000606679 | cram | 1.0 GB | ||
EGAF00000606680 | cram | 901.1 MB | ||
EGAF00000606681 | cram | 1.0 GB | ||
EGAF00000606682 | cram | 1.1 GB | ||
EGAF00000606683 | cram | 1.1 GB | ||
EGAF00000606684 | cram | 1.1 GB | ||
EGAF00000606686 | cram | 1.4 GB | ||
EGAF00000606688 | cram | 1.0 GB | ||
EGAF00000606690 | cram | 981.7 MB | ||
EGAF00000606691 | cram | 1.1 GB | ||
EGAF00000606692 | cram | 1.1 GB | ||
EGAF00000606693 | cram | 1.4 GB | ||
EGAF00000606695 | cram | 1.2 GB | ||
EGAF00000606696 | cram | 963.3 MB | ||
EGAF00000606698 | cram | 942.1 MB | ||
EGAF00000606700 | cram | 1.1 GB | ||
EGAF00000606701 | cram | 1.0 GB | ||
EGAF00000606702 | cram | 1.1 GB | ||
EGAF00000606703 | cram | 1.1 GB | ||
EGAF00000606704 | cram | 896.0 MB | ||
EGAF00000606705 | cram | 1.1 GB | ||
EGAF00000606707 | cram | 1.1 GB | ||
EGAF00000606709 | cram | 1.2 GB | ||
EGAF00000606710 | cram | 1.1 GB | ||
EGAF00000606719 | cram | 1.3 GB | ||
EGAF00000606722 | cram | 1.3 GB | ||
EGAF00000606723 | cram | 1.3 GB | ||
EGAF00000606724 | cram | 1.3 GB | ||
EGAF00000606726 | cram | 1.3 GB | ||
EGAF00000606727 | cram | 1.0 GB | ||
EGAF00000606728 | cram | 1.0 GB | ||
EGAF00000606729 | cram | 1.2 GB | ||
EGAF00000606730 | cram | 1.2 GB | ||
EGAF00000606731 | cram | 1.1 GB | ||
EGAF00000606732 | cram | 1.1 GB | ||
EGAF00000606733 | cram | 1.3 GB | ||
EGAF00000606734 | cram | 1.1 GB | ||
EGAF00000606735 | cram | 1.1 GB | ||
EGAF00000606736 | cram | 1.1 GB | ||
EGAF00000606737 | cram | 1.5 GB | ||
EGAF00000606738 | cram | 1.1 GB | ||
EGAF00000606739 | cram | 1.1 GB | ||
EGAF00000606740 | cram | 1.2 GB | ||
EGAF00000606741 | cram | 1.0 GB | ||
EGAF00000606742 | cram | 1.1 GB | ||
EGAF00000606743 | cram | 1.0 GB | ||
EGAF00000606744 | cram | 815.1 MB | ||
EGAF00000606747 | cram | 1.1 GB | ||
EGAF00000606748 | cram | 845.1 MB | ||
EGAF00000606749 | cram | 1.1 GB | ||
EGAF00000606750 | cram | 1.2 GB | ||
EGAF00000606751 | cram | 956.9 MB | ||
EGAF00000606752 | cram | 786.9 MB | ||
EGAF00000606753 | cram | 977.2 MB | ||
EGAF00000606754 | cram | 816.9 MB | ||
EGAF00000606755 | cram | 854.3 MB | ||
EGAF00000606756 | cram | 885.5 MB | ||
EGAF00000606757 | cram | 1.0 GB | ||
EGAF00000606760 | cram | 689.8 MB | ||
EGAF00000606762 | cram | 1.0 GB | ||
EGAF00000606763 | cram | 1.1 GB | ||
EGAF00000606765 | cram | 1.1 GB | ||
EGAF00000606766 | cram | 1.0 GB | ||
EGAF00000606767 | cram | 849.3 MB | ||
EGAF00000606770 | cram | 1.2 GB | ||
EGAF00000606771 | cram | 1.0 GB | ||
EGAF00000606772 | cram | 1.2 GB | ||
EGAF00000606774 | cram | 1.2 GB | ||
EGAF00000606775 | cram | 963.7 MB | ||
EGAF00000606776 | cram | 925.6 MB | ||
EGAF00000606777 | cram | 1.1 GB | ||
EGAF00000606778 | cram | 939.4 MB | ||
EGAF00000606781 | cram | 1.4 GB | ||
EGAF00000606782 | cram | 946.6 MB | ||
EGAF00000606783 | cram | 1.2 GB | ||
EGAF00000606784 | cram | 918.0 MB | ||
EGAF00000606785 | cram | 1.1 GB | ||
EGAF00000606787 | cram | 1.1 GB | ||
EGAF00000606788 | cram | 1.1 GB | ||
EGAF00000606789 | cram | 1.0 GB | ||
EGAF00000606790 | cram | 1.1 GB | ||
EGAF00000606791 | cram | 1.0 GB | ||
EGAF00000606793 | cram | 1.3 GB | ||
EGAF00000606794 | cram | 1.3 GB | ||
EGAF00000606796 | cram | 1.2 GB | ||
EGAF00000606798 | cram | 1.3 GB | ||
EGAF00000606799 | cram | 1.3 GB | ||
EGAF00000606800 | cram | 1.0 GB | ||
EGAF00000606801 | cram | 1.3 GB | ||
EGAF00000606802 | cram | 1.2 GB | ||
EGAF00000606803 | cram | 1.1 GB | ||
EGAF00000606804 | cram | 1.3 GB | ||
EGAF00000606805 | cram | 1.3 GB | ||
EGAF00000606806 | cram | 1.4 GB | ||
EGAF00000606807 | cram | 1.3 GB | ||
EGAF00000606808 | cram | 1.1 GB | ||
EGAF00000606809 | cram | 1.2 GB | ||
EGAF00000606810 | cram | 1.0 GB | ||
EGAF00000606811 | cram | 1.2 GB | ||
EGAF00000606812 | cram | 1.3 GB | ||
EGAF00000606813 | cram | 1.3 GB | ||
EGAF00000606814 | cram | 1.4 GB | ||
EGAF00000606815 | cram | 1.2 GB | ||
EGAF00000606816 | cram | 1.0 GB | ||
EGAF00000606817 | cram | 1.1 GB | ||
EGAF00000606818 | cram | 1.1 GB | ||
EGAF00000606820 | cram | 1.2 GB | ||
EGAF00000606821 | cram | 1.2 GB | ||
EGAF00000606822 | cram | 1.2 GB | ||
EGAF00000606823 | cram | 1.2 GB | ||
EGAF00000606825 | cram | 1.2 GB | ||
EGAF00000606827 | cram | 1.1 GB | ||
EGAF00000606828 | cram | 1.0 GB | ||
EGAF00000606830 | cram | 1.1 GB | ||
EGAF00000606831 | cram | 1.1 GB | ||
EGAF00000606832 | cram | 881.2 MB | ||
EGAF00000606833 | cram | 1.0 GB | ||
EGAF00000606834 | cram | 1.1 GB | ||
EGAF00000606835 | cram | 1.1 GB | ||
EGAF00000606836 | cram | 1.0 GB | ||
EGAF00000606837 | cram | 1.2 GB | ||
EGAF00000606838 | cram | 1.1 GB | ||
EGAF00000606840 | cram | 860.9 MB | ||
EGAF00000606843 | cram | 1.1 GB | ||
EGAF00000606844 | cram | 955.0 MB | ||
EGAF00000606845 | cram | 992.0 MB | ||
EGAF00000606846 | cram | 1.0 GB | ||
EGAF00000606847 | cram | 1.0 GB | ||
EGAF00000606848 | cram | 1.0 GB | ||
EGAF00000606849 | cram | 1.0 GB | ||
EGAF00000606850 | cram | 1.2 GB | ||
EGAF00000606851 | cram | 1.1 GB | ||
EGAF00000606852 | cram | 1.1 GB | ||
EGAF00000606853 | cram | 1.1 GB | ||
EGAF00000606855 | cram | 1.1 GB | ||
EGAF00000611173 | cram | 221.6 MB | ||
EGAF00000611174 | cram | 226.2 MB | ||
EGAF00000611175 | cram | 241.3 MB | ||
EGAF00000611176 | cram | 271.5 MB | ||
EGAF00000611177 | cram | 218.2 MB | ||
EGAF00000611178 | cram | 228.2 MB | ||
EGAF00000611179 | cram | 200.4 MB | ||
EGAF00000611180 | cram | 202.0 MB | ||
EGAF00000611181 | cram | 253.2 MB | ||
EGAF00000611182 | cram | 219.8 MB | ||
EGAF00000611183 | cram | 196.2 MB | ||
EGAF00000611184 | cram | 236.1 MB | ||
EGAF00000611185 | cram | 213.1 MB | ||
EGAF00000611186 | cram | 249.4 MB | ||
EGAF00000611189 | cram | 202.1 MB | ||
EGAF00000611190 | cram | 233.4 MB | ||
EGAF00000611191 | cram | 187.9 MB | ||
EGAF00000611193 | cram | 199.6 MB | ||
EGAF00000611195 | cram | 200.6 MB | ||
EGAF00000611196 | cram | 266.3 MB | ||
EGAF00000611197 | cram | 225.9 MB | ||
EGAF00000611198 | cram | 196.8 MB | ||
EGAF00000611199 | cram | 256.8 MB | ||
EGAF00000611200 | cram | 227.5 MB | ||
EGAF00000611201 | cram | 241.1 MB | ||
EGAF00000611202 | cram | 220.9 MB | ||
EGAF00000611203 | cram | 236.8 MB | ||
EGAF00000611204 | cram | 198.8 MB | ||
EGAF00000611205 | cram | 215.2 MB | ||
EGAF00000611206 | cram | 231.4 MB | ||
EGAF00000611207 | cram | 214.6 MB | ||
EGAF00000611208 | cram | 204.2 MB | ||
EGAF00000611209 | cram | 186.9 MB | ||
EGAF00000611210 | cram | 200.3 MB | ||
EGAF00000611211 | cram | 204.9 MB | ||
EGAF00000611213 | cram | 208.1 MB | ||
EGAF00000611214 | cram | 221.0 MB | ||
EGAF00000611215 | cram | 187.7 MB | ||
EGAF00000611217 | cram | 239.6 MB | ||
EGAF00000611218 | cram | 202.1 MB | ||
EGAF00000611220 | cram | 206.9 MB | ||
EGAF00000611221 | cram | 226.7 MB | ||
EGAF00000611222 | cram | 245.1 MB | ||
EGAF00000611223 | cram | 263.4 MB | ||
EGAF00000611224 | cram | 231.4 MB | ||
EGAF00000611225 | cram | 211.8 MB | ||
EGAF00000611226 | cram | 243.1 MB | ||
EGAF00000611227 | cram | 223.4 MB | ||
EGAF00000611228 | cram | 228.3 MB | ||
EGAF00000611229 | cram | 218.4 MB | ||
EGAF00000611230 | cram | 231.8 MB | ||
EGAF00000611231 | cram | 210.2 MB | ||
EGAF00000611232 | cram | 246.5 MB | ||
EGAF00000611233 | cram | 270.6 MB | ||
EGAF00000611234 | cram | 183.4 MB | ||
EGAF00000611235 | cram | 171.3 MB | ||
EGAF00000611236 | cram | 275.7 MB | ||
EGAF00000611237 | cram | 191.7 MB | ||
EGAF00000611238 | cram | 237.1 MB | ||
EGAF00000611239 | cram | 237.0 MB | ||
EGAF00000611241 | cram | 244.0 MB | ||
EGAF00000611242 | cram | 223.6 MB | ||
EGAF00000611243 | cram | 203.5 MB | ||
EGAF00000611245 | cram | 190.5 MB | ||
EGAF00000611246 | cram | 236.0 MB | ||
EGAF00000611248 | cram | 212.4 MB | ||
EGAF00000611249 | cram | 217.9 MB | ||
EGAF00000611250 | cram | 176.4 MB | ||
EGAF00000611251 | cram | 262.4 MB | ||
EGAF00000611255 | cram | 226.6 MB | ||
EGAF00000611256 | cram | 202.4 MB | ||
EGAF00000611257 | cram | 208.0 MB | ||
EGAF00000611258 | cram | 207.1 MB | ||
EGAF00000611259 | cram | 245.1 MB | ||
EGAF00000611260 | cram | 263.5 MB | ||
EGAF00000611261 | cram | 239.4 MB | ||
EGAF00000611262 | cram | 211.8 MB | ||
EGAF00000611263 | cram | 219.0 MB | ||
EGAF00000611264 | cram | 243.4 MB | ||
EGAF00000611265 | cram | 210.6 MB | ||
EGAF00000611266 | cram | 228.0 MB | ||
EGAF00000611267 | cram | 260.8 MB | ||
EGAF00000611268 | cram | 231.8 MB | ||
EGAF00000611269 | cram | 236.6 MB | ||
EGAF00000611270 | cram | 184.6 MB | ||
EGAF00000611271 | cram | 223.3 MB | ||
EGAF00000611272 | cram | 231.8 MB | ||
EGAF00000611273 | cram | 242.4 MB | ||
EGAF00000611274 | cram | 260.0 MB | ||
EGAF00000611275 | cram | 228.6 MB | ||
EGAF00000611276 | cram | 209.5 MB | ||
EGAF00000611277 | cram | 240.2 MB | ||
EGAF00000611278 | cram | 220.8 MB | ||
EGAF00000611279 | cram | 224.1 MB | ||
EGAF00000611280 | cram | 200.1 MB | ||
EGAF00000611281 | cram | 205.3 MB | ||
EGAF00000611282 | cram | 204.9 MB | ||
EGAF00000611283 | cram | 234.2 MB | ||
EGAF00000611284 | cram | 183.1 MB | ||
EGAF00000611285 | cram | 218.4 MB | ||
EGAF00000611286 | cram | 225.0 MB | ||
EGAF00000611287 | cram | 238.2 MB | ||
EGAF00000611288 | cram | 216.4 MB | ||
EGAF00000611289 | cram | 208.0 MB | ||
EGAF00000611290 | cram | 225.7 MB | ||
EGAF00000611291 | cram | 258.2 MB | ||
EGAF00000611292 | cram | 229.3 MB | ||
EGAF00000611293 | cram | 181.5 MB | ||
EGAF00000611294 | cram | 243.3 MB | ||
EGAF00000611296 | cram | 189.0 MB | ||
EGAF00000611297 | cram | 233.4 MB | ||
EGAF00000611299 | cram | 210.0 MB | ||
EGAF00000611300 | cram | 215.5 MB | ||
EGAF00000611301 | cram | 267.2 MB | ||
EGAF00000611304 | cram | 221.5 MB | ||
EGAF00000611305 | cram | 218.6 MB | ||
EGAF00000611306 | cram | 185.7 MB | ||
EGAF00000611308 | cram | 236.6 MB | ||
EGAF00000611310 | cram | 259.5 MB | ||
EGAF00000611311 | cram | 201.1 MB | ||
EGAF00000611312 | cram | 174.7 MB | ||
EGAF00000611313 | cram | 230.8 MB | ||
EGAF00000611315 | cram | 250.5 MB | ||
EGAF00000611316 | cram | 217.5 MB | ||
EGAF00000611317 | cram | 219.4 MB | ||
EGAF00000611318 | cram | 223.5 MB | ||
EGAF00000611319 | cram | 238.7 MB | ||
EGAF00000611320 | cram | 268.1 MB | ||
EGAF00000611322 | cram | 215.8 MB | ||
EGAF00000611323 | cram | 199.8 MB | ||
EGAF00000611324 | cram | 271.7 MB | ||
EGAF00000611325 | cram | 185.5 MB | ||
EGAF00000611327 | cram | 194.3 MB | ||
EGAF00000611328 | cram | 233.2 MB | ||
EGAF00000611329 | cram | 210.4 MB | ||
EGAF00000611330 | cram | 246.6 MB | ||
EGAF00000611331 | cram | 189.8 MB | ||
EGAF00000611332 | cram | 168.9 MB | ||
EGAF00000611333 | cram | 234.3 MB | ||
EGAF00000611334 | cram | 234.1 MB | ||
EGAF00000611335 | cram | 198.0 MB | ||
EGAF00000611336 | cram | 254.1 MB | ||
EGAF00000611338 | cram | 184.6 MB | ||
EGAF00000611339 | cram | 197.4 MB | ||
EGAF00000611341 | cram | 198.4 MB | ||
EGAF00000611342 | cram | 263.1 MB | ||
EGAF00000611343 | cram | 223.4 MB | ||
EGAF00000611344 | cram | 194.7 MB | ||
EGAF00000611345 | cram | 199.8 MB | ||
EGAF00000611346 | cram | 225.4 MB | ||
EGAF00000611347 | cram | 198.3 MB | ||
EGAF00000611348 | cram | 202.3 MB | ||
EGAF00000611349 | cram | 234.1 MB | ||
EGAF00000611350 | cram | 196.5 MB | ||
EGAF00000611351 | cram | 212.5 MB | ||
EGAF00000611352 | cram | 228.9 MB | ||
EGAF00000611353 | cram | 212.3 MB | ||
EGAF00000611354 | cram | 202.0 MB | ||
EGAF00000611356 | cram | 241.5 MB | ||
EGAF00000611357 | cram | 246.3 MB | ||
EGAF00000611358 | cram | 270.4 MB | ||
EGAF00000611359 | cram | 190.7 MB | ||
EGAF00000611360 | cram | 183.4 MB | ||
EGAF00000611363 | cram | 236.2 MB | ||
EGAF00000611364 | cram | 212.4 MB | ||
EGAF00000611365 | cram | 218.0 MB | ||
EGAF00000611366 | cram | 176.4 MB | ||
EGAF00000611367 | cram | 262.3 MB | ||
EGAF00000611368 | cram | 223.6 MB | ||
EGAF00000611369 | cram | 203.7 MB | ||
EGAF00000611370 | cram | 187.5 MB | ||
EGAF00000611372 | cram | 221.1 MB | ||
EGAF00000611373 | cram | 197.8 MB | ||
EGAF00000611374 | cram | 230.1 MB | ||
EGAF00000611375 | cram | 235.3 MB | ||
EGAF00000611376 | cram | 202.9 MB | ||
EGAF00000611377 | cram | 214.0 MB | ||
EGAF00000611378 | cram | 226.7 MB | ||
EGAF00000611379 | cram | 213.1 MB | ||
EGAF00000611380 | cram | 199.6 MB | ||
EGAF00000611381 | cram | 201.2 MB | ||
EGAF00000611382 | cram | 218.8 MB | ||
EGAF00000611383 | cram | 224.9 MB | ||
EGAF00000611384 | cram | 252.1 MB | ||
EGAF00000611385 | cram | 269.2 MB | ||
EGAF00000611386 | cram | 220.5 MB | ||
EGAF00000611387 | cram | 217.0 MB | ||
EGAF00000611388 | cram | 239.9 MB | ||
EGAF00000611391 | cram | 200.6 MB | ||
EGAF00000611392 | cram | 232.0 MB | ||
EGAF00000611393 | cram | 234.2 MB | ||
EGAF00000611394 | cram | 186.7 MB | ||
EGAF00000611395 | cram | 247.5 MB | ||
EGAF00000611396 | cram | 195.0 MB | ||
EGAF00000611397 | cram | 169.0 MB | ||
EGAF00000611398 | cram | 211.2 MB | ||
EGAF00000611399 | cram | 272.7 MB | ||
EGAF00000611400 | cram | 190.2 MB | ||
EGAF00000611402 | cram | 235.1 MB | ||
EGAF00000611410 | cram | 242.6 MB | ||
EGAF00000611411 | cram | 234.7 MB | ||
EGAF00000611413 | cram | 238.0 MB | ||
EGAF00000611414 | cram | 201.4 MB | ||
EGAF00000611416 | cram | 202.0 MB | ||
EGAF00000611417 | cram | 175.6 MB | ||
EGAF00000611419 | cram | 222.1 MB | ||
EGAF00000611420 | cram | 219.6 MB | ||
EGAF00000611421 | cram | 187.1 MB | ||
EGAF00000611422 | cram | 241.1 MB | ||
EGAF00000611423 | cram | 222.0 MB | ||
EGAF00000611424 | cram | 217.3 MB | ||
EGAF00000611425 | cram | 225.5 MB | ||
EGAF00000611426 | cram | 206.3 MB | ||
EGAF00000611427 | cram | 206.4 MB | ||
EGAF00000611428 | cram | 243.6 MB | ||
EGAF00000611429 | cram | 261.2 MB | ||
EGAF00000611430 | cram | 229.9 MB | ||
EGAF00000611431 | cram | 210.7 MB | ||
EGAF00000611432 | cram | 275.9 MB | ||
EGAF00000611433 | cram | 191.7 MB | ||
EGAF00000611434 | cram | 237.5 MB | ||
EGAF00000611435 | cram | 236.7 MB | ||
EGAF00000611437 | cram | 243.8 MB | ||
EGAF00000611438 | cram | 249.5 MB | ||
EGAF00000611439 | cram | 196.2 MB | ||
EGAF00000611440 | cram | 171.2 MB | ||
EGAF00000611441 | cram | 213.0 MB | ||
EGAF00000611442 | cram | 234.7 MB | ||
EGAF00000611444 | cram | 211.5 MB | ||
EGAF00000611445 | cram | 216.7 MB | ||
EGAF00000611446 | cram | 260.4 MB | ||
EGAF00000611447 | cram | 267.9 MB | ||
EGAF00000611448 | cram | 182.6 MB | ||
EGAF00000611449 | cram | 244.2 MB | ||
EGAF00000611451 | cram | 189.6 MB | ||
EGAF00000611453 | cram | 239.3 MB | ||
EGAF00000611454 | cram | 209.1 MB | ||
EGAF00000611455 | cram | 226.6 MB | ||
EGAF00000611456 | cram | 259.4 MB | ||
EGAF00000611457 | cram | 230.5 MB | ||
EGAF00000611458 | cram | 234.9 MB | ||
EGAF00000611459 | cram | 183.7 MB | ||
EGAF00000611460 | cram | 219.7 MB | ||
EGAF00000611461 | cram | 226.1 MB | ||
EGAF00000611462 | cram | 198.2 MB | ||
EGAF00000611463 | cram | 203.6 MB | ||
EGAF00000611464 | cram | 199.9 MB | ||
EGAF00000611465 | cram | 264.9 MB | ||
EGAF00000611466 | cram | 224.6 MB | ||
EGAF00000611467 | cram | 195.5 MB | ||
EGAF00000611468 | cram | 199.3 MB | ||
EGAF00000611469 | cram | 254.9 MB | ||
EGAF00000611471 | cram | 185.7 MB | ||
EGAF00000611472 | cram | 228.2 MB | ||
EGAF00000611473 | cram | 214.4 MB | ||
EGAF00000611474 | cram | 200.3 MB | ||
EGAF00000611475 | cram | 201.8 MB | ||
EGAF00000611476 | cram | 253.5 MB | ||
EGAF00000611477 | cram | 219.7 MB | ||
EGAF00000611478 | cram | 221.7 MB | ||
EGAF00000611479 | cram | 225.7 MB | ||
EGAF00000611480 | cram | 203.9 MB | ||
EGAF00000611481 | cram | 214.7 MB | ||
EGAF00000611484 | cram | 202.0 MB | ||
EGAF00000611485 | cram | 233.7 MB | ||
EGAF00000611486 | cram | 187.9 MB | ||
EGAF00000611488 | cram | 236.2 MB | ||
EGAF00000611489 | cram | 271.5 MB | ||
EGAF00000611490 | cram | 217.8 MB | ||
EGAF00000611491 | cram | 241.3 MB | ||
EGAF00000611492 | cram | 184.9 MB | ||
EGAF00000611493 | cram | 261.1 MB | ||
EGAF00000611494 | cram | 227.4 MB | ||
EGAF00000611495 | cram | 236.6 MB | ||
EGAF00000611496 | cram | 241.1 MB | ||
EGAF00000611497 | cram | 220.8 MB | ||
EGAF00000611498 | cram | 199.1 MB | ||
EGAF00000611500 | cram | 200.8 MB | ||
EGAF00000611501 | cram | 266.3 MB | ||
EGAF00000611502 | cram | 256.9 MB | ||
EGAF00000611503 | cram | 225.9 MB | ||
EGAF00000611504 | cram | 186.6 MB | ||
EGAF00000611505 | cram | 200.1 MB | ||
EGAF00000611506 | cram | 204.4 MB | ||
EGAF00000611508 | cram | 236.5 MB | ||
EGAF00000611509 | cram | 198.8 MB | ||
EGAF00000611510 | cram | 196.7 MB | ||
EGAF00000611511 | cram | 231.4 MB | ||
EGAF00000626999 | cram | 1.0 GB | ||
EGAF00000627000 | cram | 1.1 GB | ||
EGAF00000627001 | cram | 1.1 GB | ||
EGAF00000627002 | cram | 1.0 GB | ||
EGAF00000627003 | cram | 1.2 GB | ||
EGAF00000627004 | cram | 1.2 GB | ||
EGAF00000627006 | cram | 1.1 GB | ||
EGAF00000627007 | cram | 1.0 GB | ||
EGAF00000627008 | cram | 999.8 MB | ||
EGAF00000627009 | cram | 1.1 GB | ||
EGAF00000627010 | cram | 1.0 GB | ||
EGAF00000627011 | cram | 1.0 GB | ||
EGAF00000627012 | cram | 1.2 GB | ||
EGAF00000627013 | cram | 1.0 GB | ||
EGAF00000627017 | cram | 1.4 GB | ||
EGAF00000627018 | cram | 1.4 GB | ||
EGAF00000627020 | cram | 1.3 GB | ||
EGAF00000627021 | cram | 1.2 GB | ||
EGAF00000627022 | cram | 1.2 GB | ||
EGAF00000627023 | cram | 1.2 GB | ||
EGAF00000627026 | cram | 1.2 GB | ||
EGAF00000627031 | cram | 940.7 MB | ||
EGAF00000627032 | cram | 2.0 GB | ||
EGAF00000627033 | cram | 858.8 MB | ||
EGAF00000627034 | cram | 2.3 GB | ||
EGAF00000627035 | cram | 2.1 GB | ||
EGAF00000627036 | cram | 2.1 GB | ||
EGAF00000627037 | cram | 954.5 MB | ||
EGAF00000627038 | cram | 1.1 GB | ||
EGAF00000627039 | cram | 1.2 GB | ||
EGAF00000627041 | cram | 1.1 GB | ||
EGAF00000627042 | cram | 1.2 GB | ||
EGAF00000627043 | cram | 1.2 GB | ||
EGAF00000627044 | cram | 1.2 GB | ||
EGAF00000627045 | cram | 1.1 GB | ||
EGAF00000627046 | cram | 1.2 GB | ||
EGAF00000627047 | cram | 1.1 GB | ||
EGAF00000627048 | cram | 1.1 GB | ||
EGAF00000627049 | cram | 1.0 GB | ||
EGAF00000627050 | cram | 1.1 GB | ||
EGAF00000627052 | cram | 942.3 MB | ||
EGAF00000627053 | cram | 1.1 GB | ||
EGAF00000627054 | cram | 1.0 GB | ||
EGAF00000627055 | cram | 984.7 MB | ||
EGAF00000627056 | cram | 1.0 GB | ||
EGAF00000627057 | cram | 1.1 GB | ||
EGAF00000627058 | cram | 1.0 GB | ||
EGAF00000627059 | cram | 1.0 GB | ||
EGAF00000627060 | cram | 977.8 MB | ||
EGAF00000627061 | cram | 1.1 GB | ||
EGAF00000627062 | cram | 1.2 GB | ||
EGAF00000627063 | cram | 983.0 MB | ||
EGAF00000627064 | cram | 943.2 MB | ||
EGAF00000627065 | cram | 1.1 GB | ||
EGAF00000627066 | cram | 1.1 GB | ||
EGAF00000627067 | cram | 797.7 MB | ||
EGAF00000627068 | cram | 803.4 MB | ||
EGAF00000627069 | cram | 834.1 MB | ||
EGAF00000627070 | cram | 571.1 MB | ||
EGAF00000627071 | cram | 987.3 MB | ||
EGAF00000627072 | cram | 829.5 MB | ||
EGAF00000627073 | cram | 866.8 MB | ||
EGAF00000627074 | cram | 780.1 MB | ||
EGAF00000627075 | cram | 742.6 MB | ||
EGAF00000627076 | cram | 842.4 MB | ||
EGAF00000627077 | cram | 722.5 MB | ||
EGAF00000627078 | cram | 745.9 MB | ||
EGAF00000627079 | cram | 944.2 MB | ||
EGAF00000627081 | cram | 929.2 MB | ||
EGAF00000627085 | cram | 1.3 GB | ||
EGAF00000627086 | cram | 1.2 GB | ||
EGAF00000627090 | cram | 974.1 MB | ||
EGAF00000627091 | cram | 1.0 GB | ||
EGAF00000627097 | cram | 1.2 GB | ||
EGAF00001233688 | cram | 224.0 MB | ||
EGAF00001233689 | cram | 1.1 GB | ||
EGAF00001233690 | cram | 374.0 MB | ||
EGAF00001233691 | cram | 1.3 GB | ||
EGAF00001233692 | cram | 1.4 GB | ||
EGAF00001233693 | cram | 309.1 MB | ||
EGAF00001233694 | cram | 177.6 MB | ||
EGAF00001233695 | cram | 1.5 GB | ||
EGAF00001233696 | cram | 672.8 MB | ||
EGAF00001233697 | cram | 160.0 MB | ||
EGAF00001233698 | cram | 1.2 GB | ||
EGAF00001233699 | cram | 1.4 GB | ||
EGAF00001233700 | cram | 399.6 MB | ||
EGAF00001233701 | cram | 403.3 MB | ||
EGAF00001233702 | cram | 728.8 MB | ||
EGAF00001233703 | cram | 374.9 MB | ||
EGAF00001233704 | cram | 1.5 GB | ||
EGAF00001233705 | cram | 1.2 GB | ||
EGAF00001233706 | cram | 342.6 MB | ||
EGAF00001233709 | cram | 369.5 MB | ||
EGAF00001233710 | cram | 1.2 GB | ||
EGAF00001233711 | cram | 445.3 MB | ||
EGAF00001233712 | cram | 571.0 MB | ||
EGAF00001233713 | cram | 517.8 MB | ||
EGAF00001233714 | cram | 1.0 GB | ||
EGAF00001233715 | cram | 1.3 GB | ||
EGAF00001233716 | cram | 1.1 GB | ||
EGAF00001233717 | cram | 156.8 MB | ||
EGAF00001233718 | cram | 1.1 GB | ||
EGAF00001233719 | cram | 1.1 GB | ||
EGAF00001233720 | cram | 107.6 MB | ||
EGAF00001233721 | cram | 1.1 GB | ||
EGAF00001233722 | cram | 532.9 MB | ||
EGAF00001233723 | cram | 1.0 GB | ||
EGAF00001233724 | cram | 1.0 GB | ||
EGAF00001233725 | cram | 1.1 GB | ||
EGAF00001233726 | cram | 1.0 GB | ||
EGAF00001233727 | cram | 1.0 GB | ||
EGAF00001233728 | cram | 516.7 MB | ||
EGAF00001332183 | cram | 965.3 MB | ||
EGAF00001332184 | cram | 832.7 MB | ||
EGAF00001332185 | cram | 909.0 MB | ||
EGAF00001332186 | cram | 877.9 MB | ||
EGAF00001332187 | cram | 899.7 MB | ||
EGAF00001332188 | cram | 800.3 MB | ||
EGAF00001332189 | cram | 56.2 MB | ||
EGAF00001332190 | cram | 932.1 MB | ||
EGAF00001332191 | cram | 863.7 MB | ||
EGAF00001332192 | cram | 39.4 MB | ||
EGAF00001332193 | cram | 773.0 MB | ||
EGAF00001332194 | cram | 1.5 GB | ||
EGAF00001332195 | cram | 779.5 MB | ||
EGAF00001332196 | cram | 728.3 MB | ||
EGAF00001332197 | cram | 812.2 MB | ||
EGAF00001332198 | cram | 933.0 MB | ||
EGAF00001332199 | cram | 960.0 MB | ||
EGAF00001332200 | cram | 828.1 MB | ||
EGAF00001332201 | cram | 901.2 MB | ||
EGAF00001332202 | cram | 871.0 MB | ||
EGAF00001332203 | cram | 894.2 MB | ||
EGAF00001332204 | cram | 795.3 MB | ||
EGAF00001332205 | cram | 55.7 MB | ||
EGAF00001332206 | cram | 926.9 MB | ||
EGAF00001332207 | cram | 858.7 MB | ||
EGAF00001332208 | cram | 39.2 MB | ||
EGAF00001332209 | cram | 767.5 MB | ||
EGAF00001332210 | cram | 1.5 GB | ||
EGAF00001332211 | cram | 774.3 MB | ||
EGAF00001332212 | cram | 723.7 MB | ||
EGAF00001332213 | cram | 807.0 MB | ||
EGAF00001332214 | cram | 927.4 MB | ||
EGAF00001332215 | cram | 685.1 MB | ||
EGAF00001332216 | cram | 688.7 MB | ||
EGAF00001332217 | cram | 631.3 MB | ||
EGAF00001332218 | cram | 566.0 MB | ||
EGAF00001332219 | cram | 547.8 MB | ||
EGAF00001332220 | cram | 583.8 MB | ||
EGAF00001332221 | cram | 695.2 MB | ||
EGAF00001332222 | cram | 27.8 MB | ||
EGAF00001332223 | cram | 651.3 MB | ||
EGAF00001332224 | cram | 664.2 MB | ||
EGAF00001332225 | cram | 592.3 MB | ||
EGAF00001332226 | cram | 596.7 MB | ||
EGAF00001332227 | cram | 635.4 MB | ||
EGAF00001332228 | cram | 610.1 MB | ||
EGAF00001332229 | cram | 624.9 MB | ||
EGAF00001332230 | cram | 727.7 MB | ||
EGAF00001332231 | cram | 679.0 MB | ||
EGAF00001332232 | cram | 683.1 MB | ||
EGAF00001332233 | cram | 624.5 MB | ||
EGAF00001332234 | cram | 561.3 MB | ||
EGAF00001332235 | cram | 543.1 MB | ||
EGAF00001332236 | cram | 578.3 MB | ||
EGAF00001332237 | cram | 689.3 MB | ||
EGAF00001332238 | cram | 27.7 MB | ||
EGAF00001332239 | cram | 646.7 MB | ||
EGAF00001332240 | cram | 658.4 MB | ||
EGAF00001332241 | cram | 587.5 MB | ||
EGAF00001332242 | cram | 591.7 MB | ||
EGAF00001332243 | cram | 630.6 MB | ||
EGAF00001332244 | cram | 604.4 MB | ||
EGAF00001332245 | cram | 620.4 MB | ||
EGAF00001332246 | cram | 722.9 MB | ||
EGAF00001332247 | cram | 751.1 MB | ||
EGAF00001332248 | cram | 677.6 MB | ||
EGAF00001332249 | cram | 799.8 MB | ||
EGAF00001332250 | cram | 638.0 MB | ||
EGAF00001332251 | cram | 605.4 MB | ||
EGAF00001332252 | cram | 774.7 MB | ||
EGAF00001332253 | cram | 548.7 MB | ||
EGAF00001332254 | cram | 771.8 MB | ||
EGAF00001332255 | cram | 749.1 MB | ||
EGAF00001332256 | cram | 740.5 MB | ||
EGAF00001332257 | cram | 794.3 MB | ||
EGAF00001332258 | cram | 1.1 GB | ||
EGAF00001332259 | cram | 641.4 MB | ||
EGAF00001332260 | cram | 680.2 MB | ||
EGAF00001332261 | cram | 728.4 MB | ||
EGAF00001332262 | cram | 763.1 MB | ||
EGAF00001332263 | cram | 687.5 MB | ||
EGAF00001332264 | cram | 812.3 MB | ||
EGAF00001332265 | cram | 647.2 MB | ||
EGAF00001332266 | cram | 616.8 MB | ||
EGAF00001332267 | cram | 788.7 MB | ||
EGAF00001332268 | cram | 558.4 MB | ||
EGAF00001332269 | cram | 784.2 MB | ||
EGAF00001332270 | cram | 760.6 MB | ||
EGAF00001332271 | cram | 752.3 MB | ||
EGAF00001332272 | cram | 807.5 MB | ||
EGAF00001332273 | cram | 1.1 GB | ||
EGAF00001332274 | cram | 652.4 MB | ||
EGAF00001332275 | cram | 690.8 MB | ||
EGAF00001332276 | cram | 740.3 MB | ||
EGAF00001332277 | cram | 6.0 MB | ||
EGAF00001332278 | cram | 44.3 MB | ||
EGAF00001332279 | cram | 29.8 MB | ||
EGAF00001332280 | cram | 15.6 MB | ||
EGAF00001332281 | cram | 4.6 MB | ||
EGAF00001332282 | cram | 33.9 MB | ||
EGAF00001332283 | cram | 23.0 MB | ||
EGAF00001332284 | cram | 11.9 MB | ||
EGAF00001332285 | cram | 5.1 MB | ||
EGAF00001332286 | cram | 37.8 MB | ||
EGAF00001332287 | cram | 25.6 MB | ||
EGAF00001332288 | cram | 13.4 MB | ||
EGAF00001332289 | cram | 6.5 MB | ||
EGAF00001332290 | cram | 48.1 MB | ||
EGAF00001332291 | cram | 32.7 MB | ||
EGAF00001332292 | cram | 16.9 MB | ||
734 Files (424.3 GB) |