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Pilot experiment on functional genomics in osteoarthritis_RNA

The aim of this work is to apply an integrated systems approach to understand the biological underpinnings of large joint (hip and knee) osteoarthritis which culminates in the need for total joint replacement (TJR). In this pilot we will assess the feasibility of the approach in the relevant tissue. We will obtain diseased and non-diseased tissue (cartilage and endochondral bone) following TJR, coupled with a blood sample, from 12 patients. We will characterise the 12 pairs of diseased and non-diseased tissue samples in terms of transcription (RNASeq) The pilot will help assess the feasibility of isolating sufficient levels of starting material for the different approaches, and will instigate the development of analytical approaches to synthesising the resulting data.

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Wellcome Trust Sanger Institute Data Sharing Policy

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001001203 Transcriptome Analysis

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00000792120 cram 729.1 MB
EGAF00000792121 cram 674.0 MB
EGAF00000792122 cram 688.6 MB
EGAF00000792123 cram 689.0 MB
EGAF00000792124 cram 685.2 MB
EGAF00000792125 cram 736.5 MB
EGAF00000792126 cram 755.4 MB
EGAF00000792127 cram 819.7 MB
EGAF00000792128 cram 666.7 MB
EGAF00000792129 cram 720.6 MB
EGAF00000792130 cram 646.0 MB
EGAF00000792131 cram 629.2 MB
EGAF00000792132 cram 748.5 MB
EGAF00000792133 cram 707.0 MB
EGAF00000792134 cram 693.7 MB
EGAF00000792135 cram 736.4 MB
EGAF00000792136 cram 1.1 GB
EGAF00000792137 cram 711.1 MB
EGAF00000792138 cram 676.4 MB
EGAF00000792139 cram 630.8 MB
EGAF00000792140 cram 682.7 MB
EGAF00000792141 cram 733.0 MB
EGAF00000792142 cram 594.2 MB
EGAF00000792143 cram 703.6 MB
EGAF00000792144 cram 731.2 MB
EGAF00000792145 cram 669.4 MB
EGAF00000792146 cram 683.8 MB
EGAF00000792177 cram 684.3 MB
EGAF00000792178 cram 680.8 MB
EGAF00000792179 cram 730.8 MB
EGAF00000792180 cram 749.0 MB
EGAF00000792181 cram 814.0 MB
EGAF00000792182 cram 660.5 MB
EGAF00000792183 cram 714.0 MB
EGAF00000792184 cram 641.1 MB
EGAF00000792185 cram 624.6 MB
EGAF00000792186 cram 743.2 MB
EGAF00000792187 cram 701.6 MB
EGAF00000792188 cram 689.6 MB
EGAF00000792189 cram 730.5 MB
EGAF00000792190 cram 1.1 GB
EGAF00000792191 cram 705.9 MB
EGAF00000792192 cram 671.0 MB
EGAF00000792193 cram 626.5 MB
EGAF00000792194 cram 676.6 MB
EGAF00000792195 cram 728.3 MB
EGAF00000792196 cram 590.6 MB
EGAF00000792197 cram 699.7 MB
EGAF00000792198 cram 725.2 MB
EGAF00000792286 cram 544.9 MB
EGAF00000792287 cram 560.1 MB
EGAF00000792288 cram 561.3 MB
EGAF00000792289 cram 556.4 MB
EGAF00000792290 cram 597.8 MB
EGAF00000792291 cram 613.8 MB
EGAF00000792292 cram 666.6 MB
EGAF00000792293 cram 543.8 MB
EGAF00000792294 cram 583.6 MB
EGAF00000792295 cram 524.3 MB
EGAF00000792296 cram 512.7 MB
EGAF00000792297 cram 607.9 MB
EGAF00000792298 cram 574.6 MB
EGAF00000792299 cram 566.8 MB
EGAF00000792300 cram 600.4 MB
EGAF00000792301 cram 865.1 MB
EGAF00000792302 cram 580.9 MB
EGAF00000792303 cram 549.1 MB
EGAF00000792304 cram 512.0 MB
EGAF00000792305 cram 552.9 MB
EGAF00000792306 cram 596.0 MB
EGAF00000792334 cram 485.8 MB
EGAF00000792335 cram 572.8 MB
EGAF00000792336 cram 597.5 MB
EGAF00000792337 cram 673.0 MB
EGAF00000792338 cram 687.5 MB
EGAF00000792339 cram 687.2 MB
EGAF00000792340 cram 684.0 MB
EGAF00000792341 cram 731.6 MB
EGAF00000792342 cram 751.8 MB
EGAF00000792343 cram 817.7 MB
EGAF00000792344 cram 660.9 MB
EGAF00000792345 cram 714.9 MB
EGAF00000792346 cram 642.7 MB
EGAF00000792347 cram 627.0 MB
EGAF00000792348 cram 744.5 MB
EGAF00000792349 cram 703.1 MB
EGAF00000792350 cram 693.0 MB
EGAF00000792351 cram 731.2 MB
EGAF00000792352 cram 1.1 GB
EGAF00000792353 cram 708.9 MB
EGAF00000792354 cram 672.0 MB
EGAF00000792355 cram 628.5 MB
EGAF00000792356 cram 678.5 MB
EGAF00000792357 cram 731.5 MB
EGAF00000792358 cram 591.1 MB
EGAF00000792359 cram 701.1 MB
EGAF00000792360 cram 726.1 MB
EGAF00000792395 cram 673.7 MB
EGAF00000792396 cram 688.2 MB
EGAF00000792397 cram 688.6 MB
EGAF00000792398 cram 684.6 MB
EGAF00000792399 cram 735.4 MB
EGAF00000792400 cram 754.6 MB
EGAF00000792401 cram 819.3 MB
EGAF00000792402 cram 665.7 MB
EGAF00000792403 cram 719.7 MB
EGAF00000792404 cram 644.9 MB
EGAF00000792405 cram 628.7 MB
EGAF00000792406 cram 747.4 MB
EGAF00000792407 cram 706.6 MB
EGAF00000792408 cram 694.2 MB
EGAF00000792409 cram 735.8 MB
EGAF00000792410 cram 1.1 GB
EGAF00000792411 cram 710.3 MB
EGAF00000792412 cram 675.4 MB
EGAF00000792413 cram 629.8 MB
EGAF00000792414 cram 681.7 MB
EGAF00000792415 cram 732.8 MB
EGAF00000792416 cram 594.6 MB
EGAF00000792417 cram 703.8 MB
EGAF00000792418 cram 730.2 MB
EGAF00000792419 cram 672.6 MB
EGAF00000792420 cram 686.8 MB
EGAF00000792421 cram 687.3 MB
EGAF00000792422 cram 683.8 MB
EGAF00000792423 cram 734.0 MB
EGAF00000792424 cram 752.7 MB
EGAF00000792425 cram 817.7 MB
EGAF00000792426 cram 664.4 MB
EGAF00000792427 cram 717.8 MB
EGAF00000792428 cram 643.9 MB
EGAF00000792429 cram 628.0 MB
EGAF00000792430 cram 746.6 MB
EGAF00000792431 cram 704.8 MB
EGAF00000792432 cram 692.8 MB
EGAF00000792433 cram 733.7 MB
EGAF00000792434 cram 1.1 GB
EGAF00000792435 cram 709.4 MB
EGAF00000792436 cram 673.9 MB
EGAF00000792437 cram 629.0 MB
EGAF00000792438 cram 680.4 MB
EGAF00000792439 cram 731.3 MB
EGAF00000792440 cram 593.5 MB
EGAF00000792441 cram 702.2 MB
144 Files (99.3 GB)