Use of Deep Sequencing to Dectect Clonal Mutations In Sun Exposed Skin Epidermis
This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tissue sample. By analyzing small samples, clones with as few as 100 cells will be detectable. Allele frequency distributions for each mutation will be used to infer cell fate using published methods (Klein et al. 2010). This study will shed unprecedented light on the early clonal events that lead to the emergence of cancer.
- 15/08/2016
- 166 samples
- DAC: EGAC00001000000
- Technology: Illumina HiSeq 2000
- PUB DUO:0000019 (version: 2021-02-23)publication requiredThis data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community.
- US DUO:0000026 (version: 2021-02-23)user specific restrictionThis data use modifier indicates that use is limited to use by approved users.
- IS DUO:0000028 (version: 2021-02-23)institution specific restrictionThis data use modifier indicates that use is limited to use within an approved institution.
- GRU DUO:0000042 (version: 2021-02-23)general research useThis data use permission indicates that use is allowed for general research use for any research purpose.
Wellcome Trust Sanger Institute Cancer Genome Group Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001000515 | Cancer Genomics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00000602465 | bam | 904.1 MB | ||
| EGAF00000602466 | bam | 1.2 GB | ||
| EGAF00000602467 | bam | 986.0 MB | ||
| EGAF00000602468 | bam | 1.1 GB | ||
| EGAF00000602469 | bam | 1.0 GB | ||
| EGAF00000602470 | bam | 976.0 MB | ||
| EGAF00000602471 | bam | 957.9 MB | ||
| EGAF00000602472 | bam | 927.0 MB | ||
| EGAF00000602473 | bam | 1.0 GB | ||
| EGAF00000602474 | bam | 1.3 GB | ||
| EGAF00000602475 | bam | 1.2 GB | ||
| EGAF00000602476 | bam | 1.0 GB | ||
| EGAF00000602477 | bam | 1.1 GB | ||
| EGAF00000602478 | bam | 1.2 GB | ||
| EGAF00000602479 | bam | 935.3 MB | ||
| EGAF00000602480 | bam | 1.2 GB | ||
| EGAF00000602481 | bam | 831.5 MB | ||
| EGAF00000602482 | bam | 877.9 MB | ||
| EGAF00000602483 | bam | 1.1 GB | ||
| EGAF00000602484 | bam | 1.4 GB | ||
| EGAF00000602485 | bam | 893.2 MB | ||
| EGAF00000602486 | bam | 1.2 GB | ||
| EGAF00000602487 | bam | 1.1 GB | ||
| EGAF00000602488 | bam | 1.0 GB | ||
| EGAF00000602489 | bam | 1.0 GB | ||
| EGAF00000602490 | bam | 971.1 MB | ||
| EGAF00000602491 | bam | 1.1 GB | ||
| EGAF00000602492 | bam | 994.2 MB | ||
| EGAF00000602493 | bam | 1.0 GB | ||
| EGAF00000602494 | bam | 810.3 MB | ||
| EGAF00000602495 | bam | 991.2 MB | ||
| EGAF00000602496 | bam | 1.9 GB | ||
| EGAF00000602497 | cram | 430.7 MB | ||
| EGAF00000602498 | cram | 571.3 MB | ||
| EGAF00000602499 | cram | 475.4 MB | ||
| EGAF00000602500 | cram | 518.9 MB | ||
| EGAF00000602501 | cram | 495.2 MB | ||
| EGAF00000602502 | cram | 468.9 MB | ||
| EGAF00000602503 | cram | 462.2 MB | ||
| EGAF00000602504 | cram | 449.5 MB | ||
| EGAF00000602505 | cram | 488.4 MB | ||
| EGAF00000602506 | cram | 629.0 MB | ||
| EGAF00000602507 | cram | 578.5 MB | ||
| EGAF00000602508 | cram | 494.5 MB | ||
| EGAF00000602509 | cram | 512.0 MB | ||
| EGAF00000602510 | cram | 583.5 MB | ||
| EGAF00000602511 | cram | 451.9 MB | ||
| EGAF00000602512 | cram | 595.7 MB | ||
| EGAF00000602513 | cram | 395.5 MB | ||
| EGAF00000602514 | cram | 446.1 MB | ||
| EGAF00000602515 | cram | 534.4 MB | ||
| EGAF00000602516 | cram | 662.2 MB | ||
| EGAF00000602517 | cram | 429.1 MB | ||
| EGAF00000602518 | cram | 555.1 MB | ||
| EGAF00000602519 | cram | 518.7 MB | ||
| EGAF00000602520 | cram | 490.0 MB | ||
| EGAF00000602521 | cram | 505.1 MB | ||
| EGAF00000602522 | cram | 476.3 MB | ||
| EGAF00000602523 | cram | 547.4 MB | ||
| EGAF00000602524 | cram | 489.1 MB | ||
| EGAF00000602525 | cram | 492.8 MB | ||
| EGAF00000602526 | cram | 394.1 MB | ||
| EGAF00000602527 | cram | 486.5 MB | ||
| EGAF00000602528 | cram | 978.3 MB | ||
| EGAF00000602529 | cram | 430.9 MB | ||
| EGAF00000602530 | cram | 570.7 MB | ||
| EGAF00000602531 | cram | 474.7 MB | ||
| EGAF00000602532 | cram | 517.7 MB | ||
| EGAF00000602533 | cram | 494.8 MB | ||
| EGAF00000602534 | cram | 468.5 MB | ||
| EGAF00000602535 | cram | 461.4 MB | ||
| EGAF00000602536 | cram | 448.5 MB | ||
| EGAF00000602537 | cram | 488.1 MB | ||
| EGAF00000602538 | cram | 627.4 MB | ||
| EGAF00000602539 | cram | 577.8 MB | ||
| EGAF00000602540 | cram | 494.2 MB | ||
| EGAF00000602541 | cram | 511.1 MB | ||
| EGAF00000602542 | cram | 582.6 MB | ||
| EGAF00000602543 | cram | 452.0 MB | ||
| EGAF00000602544 | cram | 594.7 MB | ||
| EGAF00000602545 | cram | 394.8 MB | ||
| EGAF00000602546 | cram | 443.9 MB | ||
| EGAF00000602547 | cram | 533.5 MB | ||
| EGAF00000602548 | cram | 660.7 MB | ||
| EGAF00000602549 | cram | 428.9 MB | ||
| EGAF00000602550 | cram | 553.9 MB | ||
| EGAF00000602551 | cram | 518.5 MB | ||
| EGAF00000602552 | cram | 488.7 MB | ||
| EGAF00000602553 | cram | 504.2 MB | ||
| EGAF00000602554 | cram | 475.7 MB | ||
| EGAF00000602555 | cram | 545.5 MB | ||
| EGAF00000602556 | cram | 488.2 MB | ||
| EGAF00000602557 | cram | 492.4 MB | ||
| EGAF00000602558 | cram | 393.8 MB | ||
| EGAF00000602559 | cram | 485.8 MB | ||
| EGAF00000602560 | cram | 976.1 MB | ||
| EGAF00000602561 | cram | 431.6 MB | ||
| EGAF00000602562 | cram | 571.2 MB | ||
| EGAF00000602563 | cram | 475.8 MB | ||
| EGAF00000602564 | cram | 518.8 MB | ||
| EGAF00000602565 | cram | 495.3 MB | ||
| EGAF00000602566 | cram | 469.1 MB | ||
| EGAF00000602567 | cram | 462.3 MB | ||
| EGAF00000602568 | cram | 449.5 MB | ||
| EGAF00000602569 | cram | 488.5 MB | ||
| EGAF00000602570 | cram | 628.6 MB | ||
| EGAF00000602571 | cram | 578.9 MB | ||
| EGAF00000602572 | cram | 494.5 MB | ||
| EGAF00000602573 | cram | 511.8 MB | ||
| EGAF00000602574 | cram | 583.5 MB | ||
| EGAF00000602575 | cram | 452.2 MB | ||
| EGAF00000602576 | cram | 595.8 MB | ||
| EGAF00000602577 | cram | 396.1 MB | ||
| EGAF00000602578 | cram | 445.3 MB | ||
| EGAF00000602579 | cram | 534.1 MB | ||
| EGAF00000602580 | cram | 662.1 MB | ||
| EGAF00000602581 | cram | 429.7 MB | ||
| EGAF00000602582 | cram | 554.5 MB | ||
| EGAF00000602583 | cram | 518.8 MB | ||
| EGAF00000602584 | cram | 490.3 MB | ||
| EGAF00000602585 | cram | 503.8 MB | ||
| EGAF00000602586 | cram | 476.1 MB | ||
| EGAF00000602587 | cram | 546.5 MB | ||
| EGAF00000602588 | cram | 489.0 MB | ||
| EGAF00000602589 | cram | 492.6 MB | ||
| EGAF00000602590 | cram | 394.2 MB | ||
| EGAF00000602591 | cram | 486.1 MB | ||
| EGAF00000602592 | cram | 976.6 MB | ||
| EGAF00000606417 | cram | 2.5 GB | ||
| EGAF00000606418 | cram | 2.4 GB | ||
| EGAF00000606419 | cram | 2.3 GB | ||
| EGAF00000606420 | cram | 2.2 GB | ||
| EGAF00000606421 | cram | 2.4 GB | ||
| EGAF00000606422 | cram | 2.4 GB | ||
| EGAF00000606423 | cram | 2.4 GB | ||
| EGAF00000614806 | cram | 711.3 MB | ||
| EGAF00000614807 | cram | 660.1 MB | ||
| EGAF00000614808 | cram | 531.3 MB | ||
| EGAF00000614809 | cram | 434.8 MB | ||
| EGAF00000614810 | cram | 1.4 GB | ||
| EGAF00000614811 | cram | 493.5 MB | ||
| EGAF00000614812 | cram | 596.5 MB | ||
| EGAF00000614813 | cram | 651.3 MB | ||
| EGAF00000614814 | cram | 622.8 MB | ||
| EGAF00000614815 | cram | 702.7 MB | ||
| EGAF00000614816 | cram | 457.0 MB | ||
| EGAF00000614817 | cram | 991.8 MB | ||
| EGAF00000614818 | cram | 670.9 MB | ||
| EGAF00000614819 | cram | 678.9 MB | ||
| EGAF00000614820 | cram | 521.9 MB | ||
| EGAF00000614821 | cram | 592.8 MB | ||
| EGAF00000614822 | cram | 913.7 MB | ||
| EGAF00000614823 | cram | 1.1 GB | ||
| EGAF00000614824 | cram | 949.1 MB | ||
| EGAF00000614825 | cram | 646.8 MB | ||
| EGAF00000614826 | cram | 957.4 MB | ||
| EGAF00000614827 | cram | 1.4 GB | ||
| EGAF00000614828 | cram | 969.7 MB | ||
| EGAF00000614829 | cram | 1.1 GB | ||
| EGAF00000614830 | cram | 1.3 GB | ||
| EGAF00000614831 | cram | 1.0 GB | ||
| EGAF00000614832 | cram | 1.2 GB | ||
| EGAF00000614833 | cram | 1.2 GB | ||
| EGAF00000614834 | cram | 554.6 MB | ||
| EGAF00000614835 | cram | 1.2 GB | ||
| EGAF00000614836 | cram | 1.2 GB | ||
| EGAF00000614837 | cram | 1.1 GB | ||
| EGAF00000614838 | cram | 931.3 MB | ||
| EGAF00000614839 | cram | 906.6 MB | ||
| EGAF00000614840 | cram | 1.1 GB | ||
| EGAF00000614841 | cram | 1.0 GB | ||
| EGAF00000614842 | cram | 1.1 GB | ||
| EGAF00000614843 | cram | 1.0 GB | ||
| EGAF00000614844 | cram | 996.9 MB | ||
| EGAF00000614845 | cram | 876.7 MB | ||
| EGAF00000614846 | cram | 949.4 MB | ||
| EGAF00000614847 | cram | 1.1 GB | ||
| EGAF00000614848 | cram | 942.9 MB | ||
| EGAF00000614849 | cram | 963.7 MB | ||
| EGAF00000614850 | cram | 1.1 GB | ||
| EGAF00000614851 | cram | 974.0 MB | ||
| EGAF00000614852 | cram | 243.7 MB | ||
| EGAF00000614853 | cram | 886.0 MB | ||
| EGAF00000614854 | cram | 1.0 GB | ||
| EGAF00000614855 | cram | 939.2 MB | ||
| EGAF00000614856 | cram | 942.5 MB | ||
| EGAF00000614857 | cram | 956.6 MB | ||
| EGAF00000614858 | cram | 969.3 MB | ||
| EGAF00000614859 | cram | 1.1 GB | ||
| EGAF00000614860 | cram | 1.0 GB | ||
| EGAF00000614861 | cram | 1.0 GB | ||
| EGAF00000614862 | cram | 941.0 MB | ||
| EGAF00000614863 | cram | 1.0 GB | ||
| EGAF00000614864 | cram | 969.6 MB | ||
| EGAF00000614865 | cram | 903.5 MB | ||
| EGAF00000614866 | cram | 883.8 MB | ||
| EGAF00000614867 | cram | 946.3 MB | ||
| EGAF00000614868 | cram | 977.7 MB | ||
| EGAF00000614869 | cram | 1.0 GB | ||
| EGAF00000614870 | cram | 905.6 MB | ||
| EGAF00000614871 | cram | 904.1 MB | ||
| EGAF00000614872 | cram | 919.7 MB | ||
| EGAF00000614873 | cram | 935.8 MB | ||
| EGAF00000614874 | cram | 574.8 MB | ||
| EGAF00000614875 | cram | 1.0 GB | ||
| EGAF00000614876 | cram | 1.0 GB | ||
| EGAF00000614877 | cram | 1.0 GB | ||
| EGAF00000614878 | cram | 886.2 MB | ||
| EGAF00000614879 | cram | 890.1 MB | ||
| EGAF00000614880 | cram | 883.7 MB | ||
| EGAF00000614881 | cram | 956.1 MB | ||
| EGAF00000614882 | cram | 1.0 GB | ||
| EGAF00000614883 | cram | 973.0 MB | ||
| EGAF00000614884 | cram | 1.0 GB | ||
| EGAF00000614885 | cram | 1.1 GB | ||
| EGAF00000614886 | cram | 657.9 MB | ||
| EGAF00000614887 | cram | 814.4 MB | ||
| EGAF00000614888 | cram | 847.2 MB | ||
| EGAF00000614889 | cram | 805.8 MB | ||
| EGAF00000614890 | cram | 841.8 MB | ||
| EGAF00000614891 | cram | 854.4 MB | ||
| EGAF00000614892 | cram | 894.3 MB | ||
| EGAF00000614893 | cram | 932.0 MB | ||
| EGAF00000614894 | cram | 807.3 MB | ||
| EGAF00000614895 | cram | 846.4 MB | ||
| EGAF00000614896 | cram | 888.3 MB | ||
| EGAF00000614897 | cram | 1.0 GB | ||
| EGAF00000614898 | cram | 954.9 MB | ||
| EGAF00000614899 | cram | 664.4 MB | ||
| EGAF00000614900 | cram | 866.9 MB | ||
| EGAF00000614901 | cram | 884.2 MB | ||
| EGAF00000684347 | cram | 886.5 MB | ||
| EGAF00000684348 | cram | 928.2 MB | ||
| EGAF00000684349 | cram | 948.2 MB | ||
| EGAF00000684350 | cram | 996.1 MB | ||
| EGAF00000684351 | cram | 1.3 GB | ||
| EGAF00000684352 | cram | 1.1 GB | ||
| EGAF00000684453 | cram | 1.2 GB | ||
| EGAF00000684454 | cram | 997.9 MB | ||
| EGAF00000684455 | cram | 902.6 MB | ||
| EGAF00000684456 | cram | 975.2 MB | ||
| EGAF00000684457 | cram | 948.5 MB | ||
| EGAF00000684458 | cram | 1.0 GB | ||
| EGAF00000684459 | cram | 977.3 MB | ||
| EGAF00000684460 | cram | 1.0 GB | ||
| EGAF00000684461 | cram | 1.1 GB | ||
| EGAF00000684462 | cram | 1.0 GB | ||
| EGAF00000684463 | cram | 1.0 GB | ||
| EGAF00000684464 | cram | 1.1 GB | ||
| EGAF00000684465 | cram | 1.3 GB | ||
| EGAF00000684466 | cram | 957.5 MB | ||
| EGAF00000684467 | cram | 1.0 GB | ||
| EGAF00000684468 | cram | 1.0 GB | ||
| EGAF00000684469 | cram | 1.1 GB | ||
| EGAF00000684470 | cram | 1.2 GB | ||
| EGAF00000684471 | cram | 1.0 GB | ||
| EGAF00000684472 | cram | 929.9 MB | ||
| EGAF00000684473 | cram | 977.6 MB | ||
| EGAF00000684474 | cram | 999.3 MB | ||
| EGAF00000684475 | cram | 1.9 GB | ||
| EGAF00000684476 | cram | 1.3 GB | ||
| EGAF00000684477 | cram | 1.2 GB | ||
| 262 Files (220.7 GB) | ||||