SINGLE CELL ANALYSIS OF IN VITRO ERYTHROPOIESIS
We are developing a protocol to differentiate mouse and human induced pluripotent stem (IPS) and embryonic stem (ES) cells towards the haematopoietic pathway to generate erythrocytes in vitro. This system has many applications such as the study of the role of specific genes and human polymorphisms in infectious diseases such as malaria, as well as haematological diseases such as myelodysplastic syndrome. The nature of the in vitro differentiation process means that a heterogeneous population of cells is generated. In order to understand the types of cells produced with our protocol, we have performed a single cell analysis, which has the power to reveal the different populations of cells and their characteristics. For this, a cDNA library has been made that needs to be sequenced to obtain the gene expression profiles of the different cells. With this information we will be able to assess the quality of the differentiation protocol and improve it in order to produce better cells for the downstream applications.This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
- 13/08/2016
- 192 samples
- DAC: EGAC00001000205
- Technology: Illumina HiSeq 2500
Wellcome Trust Sanger Institute Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
Study ID | Study Title | Study Type |
---|---|---|
Transcriptome Analysis |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
ID | File Type | Size | Located in | |
---|---|---|---|---|
EGAF00000595280 | cram | 123.0 MB | ||
EGAF00000595281 | cram | 123.8 MB | ||
EGAF00000595282 | cram | 169.1 MB | ||
EGAF00000595283 | cram | 168.8 MB | ||
EGAF00000595284 | cram | 155.3 MB | ||
EGAF00000595285 | cram | 164.0 MB | ||
EGAF00000595286 | cram | 168.6 MB | ||
EGAF00000595287 | cram | 161.7 MB | ||
EGAF00000595288 | cram | 184.1 MB | ||
EGAF00000595289 | cram | 132.0 MB | ||
EGAF00000595290 | cram | 148.5 MB | ||
EGAF00000595291 | cram | 141.9 MB | ||
EGAF00000595292 | cram | 171.5 MB | ||
EGAF00000595293 | cram | 183.7 MB | ||
EGAF00000595294 | cram | 190.2 MB | ||
EGAF00000595295 | cram | 158.7 MB | ||
EGAF00000595296 | cram | 203.5 MB | ||
EGAF00000595297 | cram | 226.6 MB | ||
EGAF00000595298 | cram | 206.1 MB | ||
EGAF00000595299 | cram | 42.3 MB | ||
EGAF00000595300 | cram | 199.9 MB | ||
EGAF00000595301 | cram | 60.4 MB | ||
EGAF00000595302 | cram | 158.0 MB | ||
EGAF00000595303 | cram | 183.0 MB | ||
EGAF00000595304 | cram | 177.0 MB | ||
EGAF00000595305 | cram | 266.7 MB | ||
EGAF00000595306 | cram | 223.4 MB | ||
EGAF00000595307 | cram | 241.6 MB | ||
EGAF00000595308 | cram | 250.3 MB | ||
EGAF00000595309 | cram | 236.5 MB | ||
EGAF00000595310 | cram | 235.0 MB | ||
EGAF00000595311 | cram | 270.2 MB | ||
EGAF00000595312 | cram | 216.1 MB | ||
EGAF00000595313 | cram | 190.7 MB | ||
EGAF00000595314 | cram | 178.8 MB | ||
EGAF00000595315 | cram | 204.5 MB | ||
EGAF00000595316 | cram | 223.5 MB | ||
EGAF00000595317 | cram | 213.2 MB | ||
EGAF00000595318 | cram | 244.8 MB | ||
EGAF00000595319 | cram | 282.3 MB | ||
EGAF00000595320 | cram | 329.1 MB | ||
EGAF00000595321 | cram | 216.4 MB | ||
EGAF00000595322 | cram | 274.3 MB | ||
EGAF00000595323 | cram | 281.1 MB | ||
EGAF00000595324 | cram | 219.8 MB | ||
EGAF00000595325 | cram | 197.8 MB | ||
EGAF00000595326 | cram | 232.3 MB | ||
EGAF00000595327 | cram | 223.4 MB | ||
EGAF00000595328 | cram | 234.9 MB | ||
EGAF00000595329 | cram | 366.0 MB | ||
EGAF00000595330 | cram | 341.6 MB | ||
EGAF00000595331 | cram | 156.4 MB | ||
EGAF00000595332 | cram | 227.8 MB | ||
EGAF00000595333 | cram | 252.0 MB | ||
EGAF00000595334 | cram | 337.7 MB | ||
EGAF00000595335 | cram | 190.0 MB | ||
EGAF00000595336 | cram | 245.7 MB | ||
EGAF00000595337 | cram | 229.9 MB | ||
EGAF00000595338 | cram | 219.8 MB | ||
EGAF00000595339 | cram | 152.9 MB | ||
EGAF00000595340 | cram | 172.6 MB | ||
EGAF00000595341 | cram | 249.9 MB | ||
EGAF00000595342 | cram | 240.7 MB | ||
EGAF00000595343 | cram | 212.7 MB | ||
EGAF00000595344 | cram | 259.8 MB | ||
EGAF00000595345 | cram | 188.0 MB | ||
EGAF00000595346 | cram | 223.1 MB | ||
EGAF00000595347 | cram | 258.5 MB | ||
EGAF00000595348 | cram | 196.2 MB | ||
EGAF00000595349 | cram | 268.8 MB | ||
EGAF00000595350 | cram | 202.5 MB | ||
EGAF00000595351 | cram | 204.8 MB | ||
EGAF00000595352 | cram | 210.7 MB | ||
EGAF00000595353 | cram | 341.1 MB | ||
EGAF00000595354 | cram | 211.6 MB | ||
EGAF00000595355 | cram | 259.5 MB | ||
EGAF00000595356 | cram | 171.3 MB | ||
EGAF00000595357 | cram | 240.0 MB | ||
EGAF00000595358 | cram | 267.1 MB | ||
EGAF00000595359 | cram | 271.4 MB | ||
EGAF00000595360 | cram | 224.1 MB | ||
EGAF00000595361 | cram | 239.6 MB | ||
EGAF00000595362 | cram | 251.9 MB | ||
EGAF00000595363 | cram | 183.3 MB | ||
EGAF00000595364 | cram | 238.5 MB | ||
EGAF00000595365 | cram | 225.2 MB | ||
EGAF00000595366 | cram | 333.7 MB | ||
EGAF00000595367 | cram | 252.0 MB | ||
EGAF00000595368 | cram | 193.5 MB | ||
EGAF00000595369 | cram | 267.2 MB | ||
EGAF00000595370 | cram | 280.2 MB | ||
EGAF00000595371 | cram | 228.7 MB | ||
EGAF00000595372 | cram | 290.6 MB | ||
EGAF00000595373 | cram | 304.4 MB | ||
EGAF00000595374 | cram | 171.8 MB | ||
EGAF00000595375 | cram | 156.1 MB | ||
EGAF00000595376 | cram | 236.4 MB | ||
EGAF00000595377 | cram | 169.6 MB | ||
EGAF00000595378 | cram | 169.6 MB | ||
EGAF00000595379 | cram | 156.3 MB | ||
EGAF00000595380 | cram | 164.9 MB | ||
EGAF00000595381 | cram | 169.7 MB | ||
EGAF00000595382 | cram | 163.1 MB | ||
EGAF00000595383 | cram | 185.0 MB | ||
EGAF00000595384 | cram | 132.8 MB | ||
EGAF00000595385 | cram | 149.0 MB | ||
EGAF00000595386 | cram | 142.9 MB | ||
EGAF00000595387 | cram | 172.6 MB | ||
EGAF00000595388 | cram | 184.1 MB | ||
EGAF00000595389 | cram | 190.5 MB | ||
EGAF00000595390 | cram | 158.7 MB | ||
EGAF00000595391 | cram | 204.1 MB | ||
EGAF00000595392 | cram | 227.1 MB | ||
EGAF00000595393 | cram | 206.5 MB | ||
EGAF00000595394 | cram | 42.3 MB | ||
EGAF00000595395 | cram | 200.1 MB | ||
EGAF00000595396 | cram | 60.4 MB | ||
EGAF00000595397 | cram | 158.6 MB | ||
EGAF00000595398 | cram | 183.1 MB | ||
EGAF00000595399 | cram | 177.1 MB | ||
EGAF00000595400 | cram | 267.3 MB | ||
EGAF00000595401 | cram | 223.7 MB | ||
EGAF00000595402 | cram | 241.7 MB | ||
EGAF00000595403 | cram | 250.2 MB | ||
EGAF00000595404 | cram | 236.8 MB | ||
EGAF00000595405 | cram | 235.5 MB | ||
EGAF00000595406 | cram | 271.2 MB | ||
EGAF00000595407 | cram | 216.6 MB | ||
EGAF00000595408 | cram | 191.8 MB | ||
EGAF00000595409 | cram | 179.3 MB | ||
EGAF00000595410 | cram | 204.8 MB | ||
EGAF00000595411 | cram | 224.0 MB | ||
EGAF00000595412 | cram | 213.4 MB | ||
EGAF00000595413 | cram | 244.4 MB | ||
EGAF00000595414 | cram | 282.4 MB | ||
EGAF00000595415 | cram | 329.5 MB | ||
EGAF00000595416 | cram | 217.1 MB | ||
EGAF00000595417 | cram | 273.9 MB | ||
EGAF00000595418 | cram | 281.6 MB | ||
EGAF00000595419 | cram | 220.3 MB | ||
EGAF00000595420 | cram | 198.2 MB | ||
EGAF00000595421 | cram | 232.5 MB | ||
EGAF00000595422 | cram | 224.4 MB | ||
EGAF00000595423 | cram | 235.4 MB | ||
EGAF00000595424 | cram | 368.0 MB | ||
EGAF00000595425 | cram | 342.1 MB | ||
EGAF00000595426 | cram | 157.7 MB | ||
EGAF00000595427 | cram | 228.2 MB | ||
EGAF00000595428 | cram | 253.3 MB | ||
EGAF00000595429 | cram | 338.2 MB | ||
EGAF00000595430 | cram | 190.2 MB | ||
EGAF00000595431 | cram | 246.5 MB | ||
EGAF00000595432 | cram | 231.6 MB | ||
EGAF00000595433 | cram | 220.1 MB | ||
EGAF00000595434 | cram | 153.6 MB | ||
EGAF00000595435 | cram | 173.2 MB | ||
EGAF00000595436 | cram | 250.5 MB | ||
EGAF00000595437 | cram | 241.0 MB | ||
EGAF00000595438 | cram | 213.0 MB | ||
EGAF00000595439 | cram | 260.5 MB | ||
EGAF00000595440 | cram | 188.9 MB | ||
EGAF00000595441 | cram | 223.3 MB | ||
EGAF00000595442 | cram | 259.1 MB | ||
EGAF00000595443 | cram | 196.6 MB | ||
EGAF00000595444 | cram | 270.5 MB | ||
EGAF00000595445 | cram | 202.5 MB | ||
EGAF00000595446 | cram | 205.3 MB | ||
EGAF00000595447 | cram | 211.2 MB | ||
EGAF00000595448 | cram | 343.0 MB | ||
EGAF00000595449 | cram | 211.9 MB | ||
EGAF00000595450 | cram | 261.0 MB | ||
EGAF00000595451 | cram | 172.4 MB | ||
EGAF00000595452 | cram | 240.9 MB | ||
EGAF00000595453 | cram | 267.8 MB | ||
EGAF00000595454 | cram | 271.9 MB | ||
EGAF00000595455 | cram | 225.1 MB | ||
EGAF00000595456 | cram | 241.9 MB | ||
EGAF00000595457 | cram | 252.2 MB | ||
EGAF00000595458 | cram | 184.2 MB | ||
EGAF00000595459 | cram | 239.4 MB | ||
EGAF00000595460 | cram | 225.8 MB | ||
EGAF00000595461 | cram | 334.5 MB | ||
EGAF00000595462 | cram | 252.1 MB | ||
EGAF00000595463 | cram | 194.0 MB | ||
EGAF00000595464 | cram | 267.9 MB | ||
EGAF00000595465 | cram | 280.9 MB | ||
EGAF00000595466 | cram | 229.6 MB | ||
EGAF00000595467 | cram | 290.5 MB | ||
EGAF00000595468 | cram | 305.9 MB | ||
EGAF00000595469 | cram | 171.6 MB | ||
EGAF00000595470 | cram | 156.9 MB | ||
EGAF00000595471 | cram | 237.3 MB | ||
EGAF00000684353 | cram | 189.1 MB | ||
EGAF00000684354 | cram | 11.3 MB | ||
EGAF00000684355 | cram | 228.6 MB | ||
EGAF00000684356 | cram | 128.5 MB | ||
EGAF00000684357 | cram | 179.6 MB | ||
EGAF00000684358 | cram | 165.1 MB | ||
EGAF00000684359 | cram | 183.1 MB | ||
EGAF00000684360 | cram | 119.1 MB | ||
EGAF00000684361 | cram | 1.9 MB | ||
EGAF00000684362 | cram | 58.1 MB | ||
EGAF00000684363 | cram | 100.8 MB | ||
EGAF00000684364 | cram | 155.2 MB | ||
EGAF00000684365 | cram | 279.4 MB | ||
EGAF00000684366 | cram | 142.0 MB | ||
EGAF00000684367 | cram | 215.9 MB | ||
EGAF00000684368 | cram | 172.7 MB | ||
EGAF00000684369 | cram | 198.9 MB | ||
EGAF00000684370 | cram | 154.8 MB | ||
EGAF00000684371 | cram | 240.0 MB | ||
EGAF00000684372 | cram | 171.4 MB | ||
EGAF00000684373 | cram | 17.7 MB | ||
EGAF00000684374 | cram | 95.3 MB | ||
EGAF00000684375 | cram | 347.3 MB | ||
EGAF00000684376 | cram | 213.4 MB | ||
EGAF00000684377 | cram | 88.2 MB | ||
EGAF00000684378 | cram | 127.7 MB | ||
EGAF00000684379 | cram | 202.6 MB | ||
EGAF00000684380 | cram | 277.9 MB | ||
EGAF00000684381 | cram | 141.3 MB | ||
EGAF00000684382 | cram | 213.8 MB | ||
EGAF00000684383 | cram | 171.9 MB | ||
EGAF00000684384 | cram | 198.2 MB | ||
EGAF00000684385 | cram | 154.2 MB | ||
EGAF00000684386 | cram | 238.3 MB | ||
EGAF00000684387 | cram | 170.7 MB | ||
EGAF00000684388 | cram | 17.8 MB | ||
EGAF00000684389 | cram | 94.7 MB | ||
EGAF00000684390 | cram | 345.2 MB | ||
EGAF00000684391 | cram | 212.4 MB | ||
EGAF00000684392 | cram | 87.9 MB | ||
EGAF00000684393 | cram | 127.4 MB | ||
EGAF00000684394 | cram | 201.1 MB | ||
EGAF00000684395 | cram | 154.4 MB | ||
EGAF00000684396 | cram | 114.9 MB | ||
EGAF00000684397 | cram | 92.1 MB | ||
EGAF00000684398 | cram | 106.5 MB | ||
EGAF00000684399 | cram | 147.4 MB | ||
EGAF00000684400 | cram | 89.7 MB | ||
EGAF00000684401 | cram | 157.9 MB | ||
EGAF00000684402 | cram | 149.4 MB | ||
EGAF00000684403 | cram | 134.4 MB | ||
EGAF00000684404 | cram | 128.0 MB | ||
EGAF00000684405 | cram | 159.4 MB | ||
EGAF00000684406 | cram | 128.0 MB | ||
EGAF00000684480 | cram | 155.3 MB | ||
EGAF00000684481 | cram | 115.6 MB | ||
EGAF00000684482 | cram | 92.3 MB | ||
EGAF00000684483 | cram | 106.8 MB | ||
EGAF00000684484 | cram | 148.2 MB | ||
EGAF00000684485 | cram | 90.0 MB | ||
EGAF00000684486 | cram | 158.3 MB | ||
EGAF00000684487 | cram | 150.4 MB | ||
EGAF00000684488 | cram | 135.5 MB | ||
EGAF00000684489 | cram | 128.8 MB | ||
EGAF00000684490 | cram | 160.9 MB | ||
EGAF00000684491 | cram | 128.7 MB | ||
EGAF00000684492 | cram | 184.0 MB | ||
EGAF00000684493 | cram | 205.9 MB | ||
EGAF00000684494 | cram | 154.7 MB | ||
EGAF00000684495 | cram | 145.0 MB | ||
EGAF00000684496 | cram | 144.4 MB | ||
EGAF00000684497 | cram | 6.0 MB | ||
EGAF00000684498 | cram | 138.3 MB | ||
EGAF00000684499 | cram | 225.5 MB | ||
EGAF00000684500 | cram | 181.2 MB | ||
EGAF00000684501 | cram | 229.0 MB | ||
EGAF00000684502 | cram | 66.8 MB | ||
EGAF00000684503 | cram | 190.7 MB | ||
EGAF00000684504 | cram | 164.8 MB | ||
EGAF00000684505 | cram | 256.0 MB | ||
EGAF00000684506 | cram | 213.7 MB | ||
EGAF00000684507 | cram | 182.9 MB | ||
EGAF00000684508 | cram | 204.9 MB | ||
EGAF00000684509 | cram | 154.5 MB | ||
EGAF00000684510 | cram | 144.6 MB | ||
EGAF00000684511 | cram | 143.1 MB | ||
EGAF00000684512 | cram | 6.0 MB | ||
EGAF00000684513 | cram | 137.6 MB | ||
EGAF00000684514 | cram | 224.1 MB | ||
EGAF00000684515 | cram | 180.3 MB | ||
EGAF00000684516 | cram | 228.0 MB | ||
EGAF00000684517 | cram | 66.8 MB | ||
EGAF00000684518 | cram | 189.2 MB | ||
EGAF00000684519 | cram | 163.9 MB | ||
EGAF00000684520 | cram | 254.9 MB | ||
EGAF00000684521 | cram | 212.5 MB | ||
EGAF00000684522 | cram | 188.3 MB | ||
EGAF00000684523 | cram | 169.4 MB | ||
EGAF00000684524 | cram | 972.3 kB | ||
EGAF00000684525 | cram | 184.3 MB | ||
EGAF00000684526 | cram | 208.0 MB | ||
EGAF00000684527 | cram | 149.3 MB | ||
EGAF00000684528 | cram | 64.8 MB | ||
EGAF00000684529 | cram | 18.2 MB | ||
EGAF00000684530 | cram | 229.8 MB | ||
EGAF00000684531 | cram | 236.2 MB | ||
EGAF00000684532 | cram | 230.5 MB | ||
EGAF00000684533 | cram | 119.9 MB | ||
EGAF00000684688 | cram | 189.0 MB | ||
EGAF00000684689 | cram | 170.3 MB | ||
EGAF00000684690 | cram | 982.3 kB | ||
EGAF00000684691 | cram | 185.1 MB | ||
EGAF00000684692 | cram | 209.7 MB | ||
EGAF00000684693 | cram | 150.0 MB | ||
EGAF00000684694 | cram | 65.1 MB | ||
EGAF00000684695 | cram | 18.2 MB | ||
EGAF00000684696 | cram | 231.5 MB | ||
EGAF00000684697 | cram | 237.5 MB | ||
EGAF00000684698 | cram | 231.9 MB | ||
EGAF00000684699 | cram | 120.9 MB | ||
EGAF00000684700 | cram | 144.2 MB | ||
EGAF00000684701 | cram | 60.5 MB | ||
EGAF00000684702 | cram | 2.7 MB | ||
EGAF00000684703 | cram | 110.4 MB | ||
EGAF00000684704 | cram | 168.5 MB | ||
EGAF00000684705 | cram | 269.2 MB | ||
EGAF00000684706 | cram | 75.4 MB | ||
EGAF00000684707 | cram | 92.6 MB | ||
EGAF00000684708 | cram | 142.6 MB | ||
EGAF00000684709 | cram | 232.1 MB | ||
EGAF00000684710 | cram | 208.2 MB | ||
EGAF00000684711 | cram | 155.3 MB | ||
EGAF00000684712 | cram | 143.4 MB | ||
EGAF00000684713 | cram | 100.1 MB | ||
EGAF00000684714 | cram | 41.7 MB | ||
EGAF00000684715 | cram | 143.9 MB | ||
EGAF00000684716 | cram | 60.2 MB | ||
EGAF00000684717 | cram | 2.7 MB | ||
EGAF00000684718 | cram | 109.6 MB | ||
EGAF00000684719 | cram | 167.6 MB | ||
EGAF00000684720 | cram | 268.1 MB | ||
EGAF00000684721 | cram | 75.2 MB | ||
EGAF00000684722 | cram | 92.0 MB | ||
EGAF00000684723 | cram | 141.5 MB | ||
EGAF00000684724 | cram | 231.5 MB | ||
EGAF00000684725 | cram | 207.2 MB | ||
EGAF00000684726 | cram | 154.5 MB | ||
EGAF00000684727 | cram | 142.6 MB | ||
EGAF00000684728 | cram | 99.6 MB | ||
EGAF00000684729 | cram | 41.6 MB | ||
EGAF00000684730 | cram | 151.2 MB | ||
EGAF00000684731 | cram | 175.1 MB | ||
EGAF00000684732 | cram | 181.1 MB | ||
EGAF00000684860 | cram | 269.0 MB | ||
EGAF00000684861 | cram | 86.0 MB | ||
EGAF00000684862 | cram | 255.9 MB | ||
EGAF00000684863 | cram | 192.5 MB | ||
EGAF00000684864 | cram | 220.0 MB | ||
EGAF00000684865 | cram | 151.5 MB | ||
EGAF00000684866 | cram | 124.4 MB | ||
EGAF00000684867 | cram | 110.6 MB | ||
EGAF00000684868 | cram | 6.3 MB | ||
EGAF00000684869 | cram | 91.9 MB | ||
EGAF00000684870 | cram | 179.4 MB | ||
EGAF00000684871 | cram | 166.4 MB | ||
EGAF00000684872 | cram | 151.7 MB | ||
EGAF00000684873 | cram | 176.2 MB | ||
EGAF00000684874 | cram | 181.7 MB | ||
EGAF00000684875 | cram | 266.7 MB | ||
EGAF00000684876 | cram | 85.6 MB | ||
EGAF00000684877 | cram | 253.7 MB | ||
EGAF00000684878 | cram | 191.6 MB | ||
EGAF00000684879 | cram | 219.2 MB | ||
EGAF00000684880 | cram | 151.0 MB | ||
EGAF00000684881 | cram | 123.6 MB | ||
EGAF00000684882 | cram | 109.7 MB | ||
EGAF00000684883 | cram | 6.3 MB | ||
EGAF00000684884 | cram | 91.5 MB | ||
EGAF00000684885 | cram | 178.5 MB | ||
EGAF00000684886 | cram | 165.7 MB | ||
EGAF00000684887 | cram | 188.0 MB | ||
EGAF00000684888 | cram | 11.3 MB | ||
EGAF00000684889 | cram | 226.5 MB | ||
EGAF00000684890 | cram | 128.0 MB | ||
EGAF00000684891 | cram | 178.9 MB | ||
EGAF00000684892 | cram | 164.5 MB | ||
EGAF00000684893 | cram | 182.7 MB | ||
EGAF00000684894 | cram | 118.7 MB | ||
EGAF00000684895 | cram | 1.9 MB | ||
EGAF00000684896 | cram | 58.0 MB | ||
EGAF00000684897 | cram | 100.6 MB | ||
EGAF00000684898 | cram | 154.0 MB | ||
384 Files (70.8 GB) |