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Subclonal diversification of primary breast cancer

Cancers are ecosystems of genetically related clones, competing across space and time for limited resources. To understand the clonal structure of primary breast cancer, we applied genome and targeted sequencing to 295 samples from 49 patients’ tumors. The extent of subclonal diversification varied considerably among patients and encompassed many spatial patterns, including local growth, intraductal dissemination and clonal intermixture. Landmarks of disease progression, such as acquiring invasive or metastatic potential, arose within detectable subclones of antecedent lesions, suggesting that subclonal mutations could be relevant if actionable. No defined temporal order of mutation was evident, with the commonest genes, including PIK3CA, TP53, BRCA2, PTEN and MYC, mutated early in some, late in others, often exhibiting parallel evolution across subclones. Signatures of homologous recombination deficiency correlated with response to neoadjuvant chemotherapy. Thus, the interplay of mutation, growth and competition drives clonal structures of breast cancer that are complex, variable across patients and clinically relevant.

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Wellcome Trust Sanger Institute Cancer Genome Group Data Sharing Policy

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Cancer Genomics
Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00000414772 cram 404.5 MB
EGAF00000414773 cram 204.3 MB
EGAF00000414774 cram 528.8 MB
EGAF00000414775 cram 355.0 MB
EGAF00000414776 cram 312.1 MB
EGAF00000414777 cram 508.0 MB
EGAF00000414778 cram 458.6 MB
EGAF00000414779 cram 489.9 MB
EGAF00000414780 cram 457.8 MB
EGAF00000414781 cram 640.7 MB
EGAF00000414782 cram 505.6 MB
EGAF00000414783 cram 624.5 MB
EGAF00000414784 cram 505.3 MB
EGAF00000414785 cram 788.9 MB
EGAF00000414786 cram 624.7 MB
EGAF00000414787 cram 446.8 MB
EGAF00000414788 cram 386.0 MB
EGAF00000414789 cram 349.6 MB
EGAF00000414790 cram 368.3 MB
EGAF00000414791 cram 442.0 MB
EGAF00000414792 cram 438.5 MB
EGAF00000414793 cram 497.7 MB
EGAF00000414794 cram 418.2 MB
EGAF00000414795 cram 374.3 MB
EGAF00000414796 cram 388.2 MB
EGAF00000414797 cram 320.4 MB
EGAF00000414798 cram 401.9 MB
EGAF00000414799 cram 357.7 MB
EGAF00000414800 cram 349.5 MB
EGAF00000414801 cram 374.1 MB
EGAF00000414802 cram 300.0 MB
EGAF00000414803 cram 358.9 MB
EGAF00000414804 cram 160.6 MB
EGAF00000414805 cram 310.1 MB
EGAF00000414806 cram 495.7 MB
EGAF00000414807 cram 280.7 MB
EGAF00000483316 cram 572.8 MB
EGAF00000483317 cram 284.2 MB
EGAF00000483318 cram 735.5 MB
EGAF00000483319 cram 491.5 MB
EGAF00000483320 cram 438.4 MB
EGAF00000483321 cram 716.7 MB
EGAF00000483322 cram 647.6 MB
EGAF00000483323 cram 694.7 MB
EGAF00000483324 cram 645.4 MB
EGAF00000483325 cram 911.8 MB
EGAF00000483326 cram 698.9 MB
EGAF00000483327 cram 860.0 MB
EGAF00000483328 cram 710.1 MB
EGAF00000483329 cram 1.1 GB
EGAF00000483330 cram 871.4 MB
EGAF00000483331 cram 628.7 MB
EGAF00000483332 cram 544.4 MB
EGAF00000483333 cram 490.3 MB
EGAF00000483334 cram 520.5 MB
EGAF00000483335 cram 612.8 MB
EGAF00000483336 cram 612.5 MB
EGAF00000483337 cram 701.1 MB
EGAF00000483338 cram 590.4 MB
EGAF00000483339 cram 526.4 MB
EGAF00000483340 cram 539.5 MB
EGAF00000483341 cram 442.1 MB
EGAF00000483342 cram 558.8 MB
EGAF00000483343 cram 502.1 MB
EGAF00000483344 cram 489.4 MB
EGAF00000483345 cram 528.3 MB
EGAF00000483346 cram 424.8 MB
EGAF00000483347 cram 503.8 MB
EGAF00000483348 cram 225.1 MB
EGAF00000483349 cram 437.7 MB
EGAF00000483350 cram 685.6 MB
EGAF00000483351 cram 392.5 MB
EGAF00000487834 cram 114.4 MB
EGAF00000487835 cram 139.0 MB
EGAF00000487836 cram 382.5 MB
EGAF00000487837 cram 109.2 MB
EGAF00000487838 cram 121.5 MB
EGAF00000487839 cram 116.5 MB
EGAF00000487840 cram 192.6 MB
EGAF00000487841 cram 92.4 MB
EGAF00000487842 cram 127.1 MB
EGAF00000487843 cram 102.3 MB
EGAF00000487844 cram 227.2 MB
EGAF00000487845 cram 302.2 MB
EGAF00000487847 cram 124.6 MB
EGAF00000487848 cram 87.1 MB
EGAF00000487849 cram 17.2 MB
EGAF00000487851 cram 233.1 MB
EGAF00000487852 cram 265.9 MB
EGAF00000487853 cram 270.1 MB
EGAF00000487854 cram 288.6 MB
EGAF00000487855 cram 333.4 MB
EGAF00000487856 cram 157.5 MB
EGAF00000487857 cram 152.8 MB
EGAF00000487858 cram 123.3 MB
EGAF00000487859 cram 104.1 MB
EGAF00000487860 cram 205.8 MB
EGAF00000487861 cram 216.9 MB
EGAF00000487862 cram 207.1 MB
EGAF00000487863 cram 188.1 MB
EGAF00000487864 cram 145.1 MB
EGAF00000487865 cram 47.6 MB
EGAF00000487866 cram 79.9 MB
EGAF00000487867 cram 151.2 MB
EGAF00000487868 cram 145.6 MB
EGAF00000487869 cram 254.8 MB
EGAF00000487870 cram 177.9 MB
EGAF00000487871 cram 189.4 MB
EGAF00000487872 cram 168.8 MB
EGAF00000487873 cram 225.1 MB
EGAF00000487874 cram 190.1 MB
EGAF00000487875 cram 153.6 MB
EGAF00000487876 cram 175.6 MB
EGAF00000487877 cram 172.6 MB
EGAF00000487878 cram 242.7 MB
EGAF00000487879 cram 187.7 MB
EGAF00000487880 cram 229.6 MB
EGAF00000487881 cram 203.5 MB
EGAF00000487882 cram 68.4 MB
EGAF00000487883 cram 179.2 MB
EGAF00000487884 cram 320.3 MB
EGAF00000487885 cram 217.6 MB
EGAF00000487886 cram 262.5 MB
EGAF00000487887 cram 280.0 MB
EGAF00000487888 cram 80.3 MB
EGAF00000487889 cram 82.8 MB
EGAF00000487890 cram 84.5 MB
EGAF00000487891 cram 97.8 MB
EGAF00000487892 cram 238.3 MB
EGAF00000487893 cram 145.4 MB
EGAF00000487894 cram 101.4 MB
EGAF00000487895 cram 200.9 MB
EGAF00000487896 cram 223.6 MB
EGAF00000487897 cram 183.3 MB
EGAF00000487898 cram 155.8 MB
EGAF00000487899 cram 170.0 MB
EGAF00000487900 cram 180.5 MB
EGAF00000487901 cram 157.5 MB
EGAF00000487902 cram 204.9 MB
EGAF00000487903 cram 136.1 MB
EGAF00000487904 cram 167.4 MB
EGAF00000487905 cram 198.2 MB
EGAF00000487906 cram 146.7 MB
EGAF00000487907 cram 151.3 MB
EGAF00000487908 cram 202.1 MB
EGAF00000487909 cram 224.0 MB
EGAF00000487910 cram 180.2 MB
EGAF00000487911 cram 134.8 MB
EGAF00000487912 cram 197.0 MB
EGAF00000487913 cram 285.7 MB
EGAF00000487914 cram 342.0 MB
EGAF00000487915 cram 241.3 MB
EGAF00000487916 cram 290.4 MB
EGAF00000487917 cram 808.7 MB
EGAF00000487918 cram 466.2 MB
EGAF00000487919 cram 227.0 MB
EGAF00000487920 cram 335.2 MB
EGAF00000487921 cram 60.4 MB
EGAF00000487922 cram 182.9 MB
EGAF00000487923 cram 11.0 MB
EGAF00000487924 cram 31.4 MB
EGAF00000487925 cram 152.8 MB
EGAF00000487926 cram 82.3 MB
EGAF00000487927 cram 67.2 MB
EGAF00000487928 cram 174.4 MB
EGAF00000487930 cram 168.7 MB
EGAF00000487931 cram 109.1 MB
EGAF00000487932 cram 169.3 MB
EGAF00000487933 cram 206.2 MB
EGAF00000487934 cram 13.4 MB
EGAF00000487935 cram 170.3 MB
EGAF00000487936 cram 162.1 MB
EGAF00000487937 cram 115.4 MB
EGAF00000487938 cram 23.5 MB
EGAF00000487939 cram 106.4 MB
EGAF00000487940 cram 250.3 MB
EGAF00000487941 cram 102.6 MB
EGAF00000487942 cram 41.5 MB
EGAF00000487943 cram 360.7 MB
EGAF00000487944 cram 188.4 MB
EGAF00000487945 cram 123.2 MB
EGAF00000487946 cram 155.4 MB
EGAF00000487947 cram 138.4 MB
EGAF00000487948 cram 141.1 MB
EGAF00000487949 cram 212.7 MB
EGAF00000487950 cram 165.6 MB
EGAF00000487951 cram 102.5 MB
EGAF00000487952 cram 105.1 MB
EGAF00000487953 cram 121.7 MB
EGAF00000487954 cram 80.9 MB
EGAF00000487955 cram 117.5 MB
EGAF00000487956 cram 82.4 MB
EGAF00000487957 cram 102.8 MB
EGAF00000487958 cram 134.7 MB
EGAF00000487959 cram 123.1 MB
EGAF00000487960 cram 133.7 MB
EGAF00000487961 cram 124.6 MB
EGAF00000487962 cram 109.4 MB
EGAF00000487963 cram 96.3 MB
EGAF00000487964 cram 94.5 MB
EGAF00000487965 cram 191.1 MB
EGAF00000487966 cram 141.5 MB
EGAF00000487967 cram 183.5 MB
EGAF00000487968 cram 123.5 MB
EGAF00000487969 cram 71.8 MB
EGAF00000487970 cram 135.6 MB
EGAF00000487971 cram 272.2 MB
EGAF00000487972 cram 142.3 MB
EGAF00000487973 cram 168.0 MB
EGAF00000487974 cram 183.4 MB
EGAF00000487975 cram 200.0 MB
EGAF00000487976 cram 165.4 MB
EGAF00000487977 cram 236.3 MB
EGAF00000487978 cram 172.3 MB
EGAF00000487979 cram 166.7 MB
EGAF00000487980 cram 148.4 MB
EGAF00000487981 cram 222.5 MB
EGAF00000487982 cram 309.5 MB
EGAF00000487983 cram 157.4 MB
EGAF00000487984 cram 250.3 MB
EGAF00000487985 cram 288.9 MB
EGAF00000487986 cram 198.7 MB
EGAF00000487987 cram 315.0 MB
EGAF00000487988 cram 339.3 MB
EGAF00000487989 cram 416.1 MB
EGAF00000487990 cram 260.7 MB
EGAF00000487991 cram 428.3 MB
EGAF00000487992 cram 349.1 MB
EGAF00000487993 cram 394.3 MB
EGAF00000487994 cram 297.8 MB
EGAF00000487995 cram 206.9 MB
EGAF00000487996 cram 227.1 MB
EGAF00000487997 cram 229.4 MB
EGAF00000487998 cram 176.4 MB
EGAF00000487999 cram 340.0 MB
EGAF00000488000 cram 111.1 MB
EGAF00000488001 cram 256.8 MB
EGAF00000488002 cram 291.0 MB
EGAF00000488003 cram 108.7 MB
EGAF00000488004 cram 229.7 MB
EGAF00000488005 cram 111.0 MB
EGAF00000488007 cram 119.2 MB
EGAF00000488008 cram 145.4 MB
EGAF00000488009 cram 399.2 MB
EGAF00000488010 cram 112.6 MB
EGAF00000488011 cram 126.6 MB
EGAF00000488012 cram 122.5 MB
EGAF00000488013 cram 200.8 MB
EGAF00000488014 cram 96.0 MB
EGAF00000488015 cram 130.2 MB
EGAF00000488016 cram 109.6 MB
EGAF00000488017 cram 236.8 MB
EGAF00000488018 cram 314.8 MB
EGAF00000488020 cram 129.2 MB
EGAF00000488021 cram 89.8 MB
EGAF00000488022 cram 18.1 MB
EGAF00000488024 cram 242.4 MB
EGAF00000488025 cram 278.1 MB
EGAF00000488026 cram 282.6 MB
EGAF00000488027 cram 302.9 MB
EGAF00000488028 cram 351.4 MB
EGAF00000488029 cram 165.5 MB
EGAF00000488030 cram 158.5 MB
EGAF00000488031 cram 128.9 MB
EGAF00000488032 cram 108.5 MB
EGAF00000488033 cram 218.0 MB
EGAF00000488034 cram 229.5 MB
EGAF00000488035 cram 215.4 MB
EGAF00000488036 cram 197.6 MB
EGAF00000488037 cram 151.7 MB
EGAF00000488038 cram 49.4 MB
EGAF00000488039 cram 83.4 MB
EGAF00000488040 cram 157.9 MB
EGAF00000488041 cram 153.2 MB
EGAF00000488042 cram 268.0 MB
EGAF00000488043 cram 186.9 MB
EGAF00000488044 cram 199.1 MB
EGAF00000488045 cram 178.1 MB
EGAF00000488046 cram 235.6 MB
EGAF00000488047 cram 198.8 MB
EGAF00000488048 cram 167.7 MB
EGAF00000488049 cram 187.3 MB
EGAF00000488050 cram 183.9 MB
EGAF00000488051 cram 255.6 MB
EGAF00000488052 cram 195.5 MB
EGAF00000488053 cram 238.3 MB
EGAF00000488054 cram 212.7 MB
EGAF00000488055 cram 70.6 MB
EGAF00000488056 cram 186.6 MB
EGAF00000488057 cram 336.6 MB
EGAF00000488058 cram 226.5 MB
EGAF00000488059 cram 273.1 MB
EGAF00000488060 cram 291.5 MB
EGAF00000488061 cram 83.5 MB
EGAF00000488062 cram 85.9 MB
EGAF00000488063 cram 89.1 MB
EGAF00000488064 cram 103.4 MB
EGAF00000488065 cram 253.4 MB
EGAF00000488066 cram 151.9 MB
EGAF00000488067 cram 107.0 MB
EGAF00000488068 cram 210.1 MB
EGAF00000488069 cram 234.1 MB
EGAF00000488070 cram 191.7 MB
EGAF00000488071 cram 165.9 MB
EGAF00000488072 cram 178.3 MB
EGAF00000488073 cram 191.6 MB
EGAF00000488074 cram 164.3 MB
EGAF00000488075 cram 217.5 MB
EGAF00000488076 cram 142.6 MB
EGAF00000488077 cram 175.4 MB
EGAF00000488078 cram 210.2 MB
EGAF00000488079 cram 154.3 MB
EGAF00000488080 cram 160.6 MB
EGAF00000488081 cram 213.9 MB
EGAF00000488082 cram 234.1 MB
EGAF00000488083 cram 188.2 MB
EGAF00000488084 cram 139.3 MB
EGAF00000488085 cram 208.1 MB
EGAF00000488086 cram 303.2 MB
EGAF00000488087 cram 360.6 MB
EGAF00000488088 cram 251.2 MB
EGAF00000488089 cram 302.6 MB
EGAF00000488090 cram 845.4 MB
EGAF00000488091 cram 485.2 MB
EGAF00000488092 cram 237.2 MB
EGAF00000488093 cram 354.6 MB
EGAF00000488094 cram 35.6 MB
EGAF00000488095 cram 106.6 MB
EGAF00000488096 cram 6.5 MB
EGAF00000488097 cram 18.7 MB
EGAF00000488098 cram 89.5 MB
EGAF00000488099 cram 49.0 MB
EGAF00000488100 cram 39.5 MB
EGAF00000488101 cram 101.6 MB
EGAF00000488103 cram 98.8 MB
EGAF00000488104 cram 63.6 MB
EGAF00000488105 cram 99.2 MB
EGAF00000488106 cram 121.2 MB
EGAF00000488107 cram 8.0 MB
EGAF00000488108 cram 100.5 MB
EGAF00000488109 cram 94.8 MB
EGAF00000488110 cram 67.5 MB
EGAF00000488111 cram 14.0 MB
EGAF00000488112 cram 61.8 MB
EGAF00000488113 cram 146.3 MB
EGAF00000488114 cram 60.6 MB
EGAF00000488115 cram 24.4 MB
EGAF00000488116 cram 210.0 MB
EGAF00000488117 cram 110.7 MB
EGAF00000488118 cram 71.8 MB
EGAF00000488119 cram 89.8 MB
EGAF00000488120 cram 81.7 MB
EGAF00000488121 cram 82.1 MB
EGAF00000488122 cram 124.9 MB
EGAF00000488123 cram 97.6 MB
EGAF00000488124 cram 59.8 MB
EGAF00000488125 cram 61.3 MB
EGAF00000488126 cram 71.2 MB
EGAF00000488127 cram 47.2 MB
EGAF00000488128 cram 68.8 MB
EGAF00000488129 cram 48.0 MB
EGAF00000488130 cram 60.0 MB
EGAF00000488131 cram 79.7 MB
EGAF00000488132 cram 71.8 MB
EGAF00000488133 cram 78.0 MB
EGAF00000488134 cram 73.0 MB
EGAF00000488135 cram 64.1 MB
EGAF00000488136 cram 55.7 MB
EGAF00000488137 cram 55.0 MB
EGAF00000488138 cram 112.1 MB
EGAF00000488139 cram 82.8 MB
EGAF00000488140 cram 108.0 MB
EGAF00000488141 cram 72.4 MB
EGAF00000488142 cram 41.9 MB
EGAF00000488143 cram 79.9 MB
EGAF00000488144 cram 161.5 MB
EGAF00000488145 cram 83.1 MB
EGAF00000488146 cram 98.6 MB
EGAF00000488147 cram 108.0 MB
EGAF00000488148 cram 118.5 MB
EGAF00000488149 cram 97.4 MB
EGAF00000488150 cram 138.3 MB
EGAF00000488151 cram 100.0 MB
EGAF00000488152 cram 96.9 MB
EGAF00000488153 cram 85.8 MB
EGAF00000488154 cram 130.9 MB
EGAF00000488155 cram 181.0 MB
EGAF00000488156 cram 91.7 MB
EGAF00000488157 cram 147.8 MB
EGAF00000488158 cram 169.1 MB
EGAF00000488159 cram 115.7 MB
EGAF00000488160 cram 182.2 MB
EGAF00000488161 cram 197.6 MB
EGAF00000488162 cram 240.7 MB
EGAF00000488163 cram 151.6 MB
EGAF00000488164 cram 253.8 MB
EGAF00000488165 cram 205.8 MB
EGAF00000488166 cram 232.5 MB
EGAF00000488167 cram 171.8 MB
EGAF00000488168 cram 118.4 MB
EGAF00000488169 cram 135.9 MB
EGAF00000488170 cram 134.3 MB
EGAF00000488171 cram 102.5 MB
EGAF00000488172 cram 201.6 MB
EGAF00000488173 cram 65.7 MB
EGAF00000488174 cram 148.0 MB
EGAF00000488175 cram 171.2 MB
EGAF00000488176 cram 63.8 MB
EGAF00000488177 cram 135.1 MB
EGAF00000488178 cram 64.8 MB
EGAF00000488179 cram 36.1 MB
EGAF00000488180 cram 108.6 MB
EGAF00000488181 cram 6.6 MB
EGAF00000488182 cram 18.9 MB
EGAF00000488183 cram 91.2 MB
EGAF00000488184 cram 49.8 MB
EGAF00000488185 cram 40.2 MB
EGAF00000488186 cram 103.5 MB
EGAF00000488188 cram 100.2 MB
EGAF00000488189 cram 64.6 MB
EGAF00000488190 cram 101.0 MB
EGAF00000488191 cram 123.3 MB
EGAF00000488192 cram 8.1 MB
EGAF00000488193 cram 102.1 MB
EGAF00000488194 cram 96.3 MB
EGAF00000488195 cram 68.7 MB
EGAF00000488196 cram 14.3 MB
EGAF00000488197 cram 63.0 MB
EGAF00000488198 cram 148.6 MB
EGAF00000488199 cram 61.5 MB
EGAF00000488200 cram 24.7 MB
EGAF00000488201 cram 213.3 MB
EGAF00000488202 cram 112.3 MB
EGAF00000488203 cram 73.0 MB
EGAF00000488204 cram 91.1 MB
EGAF00000488205 cram 82.8 MB
EGAF00000488206 cram 83.4 MB
EGAF00000488207 cram 126.9 MB
EGAF00000488208 cram 99.2 MB
EGAF00000488209 cram 60.7 MB
EGAF00000488210 cram 62.3 MB
EGAF00000488211 cram 72.4 MB
EGAF00000488212 cram 48.1 MB
EGAF00000488213 cram 70.1 MB
EGAF00000488214 cram 48.8 MB
EGAF00000488215 cram 60.9 MB
EGAF00000488216 cram 81.1 MB
EGAF00000488217 cram 73.0 MB
EGAF00000488218 cram 79.3 MB
EGAF00000488219 cram 74.2 MB
EGAF00000488220 cram 65.1 MB
EGAF00000488221 cram 56.6 MB
EGAF00000488222 cram 56.0 MB
EGAF00000488223 cram 113.7 MB
EGAF00000488224 cram 84.2 MB
EGAF00000488225 cram 109.8 MB
EGAF00000488226 cram 73.7 MB
EGAF00000488227 cram 42.7 MB
EGAF00000488228 cram 81.1 MB
EGAF00000488229 cram 164.0 MB
EGAF00000488230 cram 84.6 MB
EGAF00000488231 cram 100.5 MB
EGAF00000488232 cram 109.7 MB
EGAF00000488233 cram 120.1 MB
EGAF00000488234 cram 99.0 MB
EGAF00000488235 cram 140.6 MB
EGAF00000488236 cram 101.3 MB
EGAF00000488237 cram 98.2 MB
EGAF00000488238 cram 87.3 MB
EGAF00000488239 cram 133.3 MB
EGAF00000488240 cram 183.9 MB
EGAF00000488241 cram 93.3 MB
EGAF00000488242 cram 150.2 MB
EGAF00000488243 cram 172.0 MB
EGAF00000488244 cram 117.3 MB
EGAF00000488245 cram 185.3 MB
EGAF00000488246 cram 201.0 MB
EGAF00000488247 cram 244.9 MB
EGAF00000488248 cram 154.3 MB
EGAF00000488249 cram 258.0 MB
EGAF00000488250 cram 209.1 MB
EGAF00000488251 cram 236.5 MB
EGAF00000488252 cram 174.8 MB
EGAF00000488253 cram 120.3 MB
EGAF00000488254 cram 138.7 MB
EGAF00000488255 cram 136.7 MB
EGAF00000488256 cram 104.2 MB
EGAF00000488257 cram 205.2 MB
EGAF00000488258 cram 66.7 MB
EGAF00000488259 cram 150.3 MB
EGAF00000488260 cram 174.2 MB
EGAF00000488261 cram 65.1 MB
EGAF00000488262 cram 137.6 MB
EGAF00000488263 cram 65.8 MB
EGAF00000488264 cram 36.2 MB
EGAF00000488265 cram 108.7 MB
EGAF00000488266 cram 6.6 MB
EGAF00000488267 cram 19.1 MB
EGAF00000488268 cram 91.6 MB
EGAF00000488269 cram 50.1 MB
EGAF00000488270 cram 40.3 MB
EGAF00000488271 cram 104.0 MB
EGAF00000488273 cram 100.8 MB
EGAF00000488274 cram 64.6 MB
EGAF00000488275 cram 101.6 MB
EGAF00000488276 cram 123.6 MB
EGAF00000488277 cram 8.1 MB
EGAF00000488278 cram 102.7 MB
EGAF00000488279 cram 97.0 MB
EGAF00000488280 cram 69.1 MB
EGAF00000488281 cram 14.2 MB
EGAF00000488282 cram 63.5 MB
EGAF00000488283 cram 149.4 MB
EGAF00000488284 cram 61.8 MB
EGAF00000488285 cram 24.8 MB
EGAF00000488286 cram 214.6 MB
EGAF00000488287 cram 112.9 MB
EGAF00000488288 cram 73.4 MB
EGAF00000488289 cram 91.7 MB
EGAF00000488290 cram 83.2 MB
EGAF00000488291 cram 83.8 MB
EGAF00000488292 cram 127.5 MB
EGAF00000488293 cram 99.5 MB
EGAF00000488294 cram 60.9 MB
EGAF00000488295 cram 62.6 MB
EGAF00000488296 cram 72.8 MB
EGAF00000488297 cram 48.2 MB
EGAF00000488298 cram 70.3 MB
EGAF00000488299 cram 48.9 MB
EGAF00000488300 cram 61.4 MB
EGAF00000488301 cram 81.3 MB
EGAF00000488302 cram 73.4 MB
EGAF00000488303 cram 79.6 MB
EGAF00000488304 cram 74.7 MB
EGAF00000488305 cram 65.6 MB
EGAF00000488306 cram 56.7 MB
EGAF00000488307 cram 56.3 MB
EGAF00000488308 cram 114.2 MB
EGAF00000488309 cram 84.5 MB
EGAF00000488310 cram 110.4 MB
EGAF00000488311 cram 74.1 MB
EGAF00000488312 cram 42.8 MB
EGAF00000488313 cram 81.5 MB
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EGAF00000586323 bam 1.9 GB
EGAF00000586324 bam 2.0 GB
1113 Files (338.5 GB)