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Deep-Seq: Resistance to anti-EGFR therapy in colorectal cancer

In this study we performed ultra deep sequencing of genes associated with anti-EGFR resistance, such as KRAS, BRAF, PIK3CA, and EGFR in 17 plasma-DNA samples from a total of 10 patients treated with anti-EGFR therapy.

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CTC - Plasma-DNA - MONDO:0005575

European Genome-Phenome Archivec/o European Bioinformatics InstituteWellcome Trust Genome CampusHinxtonCambridgeCB10 1SDUnited KingdomTo whom it may concern,This document refers to the study EGAS00001000337 which has been submitted to the European Genome Archive (EGA) for the restricted access by legitimate academic institutions that have agreed to comply with the terms of a Data Access Agreement drafted by Ellen Heitzer.There are a number of steps that a researcher must take to obtain access to this data and the process is overseen by Ellen HeitzerEllen Heitzer is a Postdoctoral Fellow and is authorized to approve researchers to have encrypted access to the data submitted to the EGA. Please be advised that Ellen Heitzer (ellen.heitzer@medunigraz.at) is authorized to upload data to the EGA for archiving and distribution as part of your submission process, which will enable approved researchers to have encrypted access to the data. We can confirm that this submission is consistent with the informed consent of the participants of the study or has been granted ethical approval and is in accordance with the applicable laws and regulations.Sincerely,Michael R. SpeicherPrinciple Investigator

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00000278907 fastq.gz 4.8 MB
EGAF00000278908 fastq.gz 11.4 MB
EGAF00000278909 fastq.gz 14.5 MB
EGAF00000278910 fastq.gz 21.5 MB
EGAF00000278911 fastq.gz 25.0 MB
EGAF00000278912 fastq.gz 37.7 MB
EGAF00000278913 fastq.gz 9.3 MB
EGAF00000278914 fastq.gz 14.2 MB
EGAF00000278915 fastq.gz 691.0 kB
EGAF00000278916 fastq.gz 116.8 MB
EGAF00000278917 fastq.gz 74.9 MB
EGAF00000278918 fastq.gz 6.8 MB
EGAF00000278919 fastq.gz 21.4 MB
EGAF00000278920 fastq.gz 4.8 MB
EGAF00000278921 fastq.gz 734.4 kB
EGAF00000278922 fastq.gz 765.8 kB
EGAF00000278923 fastq.gz 613.0 kB
EGAF00000278924 fastq.gz 38.2 MB
EGAF00000278925 fastq.gz 13.8 MB
EGAF00000278926 fastq.gz 16.7 MB
EGAF00000278927 fastq.gz 14.4 MB
EGAF00000278928 fastq.gz 590.7 kB
EGAF00000278929 fastq.gz 25.9 MB
EGAF00000278930 fastq.gz 22.3 MB
EGAF00000278931 fastq.gz 47.9 MB
EGAF00000278932 fastq.gz 48.5 MB
EGAF00000278933 fastq.gz 5.6 MB
EGAF00000278934 fastq.gz 706.7 kB
EGAF00000278935 fastq.gz 806.9 kB
EGAF00000278936 fastq.gz 32.1 MB
EGAF00000278937 fastq.gz 52.2 MB
EGAF00000278938 fastq.gz 697.3 kB
EGAF00000278939 fastq.gz 9.1 MB
EGAF00000278940 fastq.gz 2.0 MB
EGAF00000278941 fastq.gz 2.5 MB
EGAF00000278942 fastq.gz 12.3 MB
EGAF00000278943 fastq.gz 8.2 MB
EGAF00000278944 fastq.gz 11.7 MB
EGAF00000278945 fastq.gz 8.8 MB
EGAF00000278946 fastq.gz 31.4 MB
EGAF00000278947 fastq.gz 5.2 MB
EGAF00000278948 fastq.gz 17.9 MB
EGAF00000278949 fastq.gz 4.6 MB
EGAF00000278950 fastq.gz 27.8 MB
EGAF00000278951 fastq.gz 7.4 MB
EGAF00000278952 fastq.gz 27.6 MB
EGAF00000278953 fastq.gz 14.9 MB
EGAF00000278954 fastq.gz 7.6 MB
EGAF00000278955 fastq.gz 25.8 MB
EGAF00000278956 fastq.gz 6.3 MB
EGAF00000278957 fastq.gz 27.7 MB
EGAF00000278958 fastq.gz 9.1 MB
EGAF00000278959 fastq.gz 17.3 MB
EGAF00000278960 fastq.gz 10.7 MB
EGAF00000278961 fastq.gz 13.1 MB
EGAF00000278962 fastq.gz 11.4 MB
EGAF00000278963 fastq.gz 8.7 MB
EGAF00000278964 fastq.gz 28.2 MB
EGAF00000278965 fastq.gz 11.4 MB
EGAF00000278966 fastq.gz 51.6 MB
EGAF00000278967 fastq.gz 16.5 MB
EGAF00000278968 fastq.gz 11.6 MB
EGAF00000278969 fastq.gz 7.0 MB
EGAF00000278970 fastq.gz 52.8 MB
EGAF00000278971 fastq.gz 8.5 MB
EGAF00000278972 fastq.gz 8.9 MB
EGAF00000278973 fastq.gz 17.5 MB
EGAF00000278974 fastq.gz 8.0 MB
EGAF00000278975 fastq.gz 6.0 MB
EGAF00000278976 fastq.gz 32.7 MB
EGAF00000481356 bam 23.1 MB
EGAF00000481357 bam 46.4 MB
EGAF00000481358 bam 29.5 MB
EGAF00000481359 bam 74.8 MB
EGAF00000481360 bam 58.7 MB
EGAF00000481361 bam 80.4 MB
EGAF00000481362 bam 68.7 MB
EGAF00000481363 bam 82.1 MB
EGAF00000481364 bam 44.4 MB
EGAF00000481365 bam 76.5 MB
EGAF00000481366 bam 24.8 MB
EGAF00000481367 bam 100.1 MB
EGAF00000481368 bam 51.5 MB
EGAF00000481369 bam 168.6 MB
EGAF00000481370 bam 137.5 MB
EGAF00000481371 bam 122.2 MB
EGAF00000481372 bam 118.3 MB
EGAF00000481373 bam 48.8 MB
EGAF00000481374 bam 121.9 MB
EGAF00000481375 bam 123.2 MB
EGAF00000481376 bam 99.2 MB
EGAF00000481377 bam 141.8 MB
EGAF00000481378 bam 60.2 MB
EGAF00000481379 bam 21.9 MB
EGAF00000481380 bam 35.5 MB
95 Files (3.2 GB)