The Transcriptome of PLX4032 resistance
We have collected material from a patient who had BrafV600E mutant melanoma that was treated with PLX4032. We have germline DNA from the patient and DNA and RNA from distinct lesions before and after treatment with PLX4032. We have transcriptome sequenced these samples to obtain a snap shot of the mechanisms of resistance that are operative.
- 27/05/2015
- 6 samples
- DAC: EGAC00001000205
- Technology: Illumina HiSeq 2000
Wellcome Trust Sanger Institute Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001000413 | Transcriptome Analysis |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00000188566 | bam | 230.0 MB | ||
| EGAF00000188567 | bam | 257.0 MB | ||
| EGAF00000188568 | bam | 274.5 MB | ||
| EGAF00000188569 | bam | 330.6 MB | ||
| EGAF00000188570 | bam | 322.9 MB | ||
| EGAF00000188571 | bam | 251.1 MB | ||
| EGAF00000188572 | bam | 228.9 MB | ||
| EGAF00000188573 | bam | 255.9 MB | ||
| EGAF00000188574 | bam | 272.8 MB | ||
| EGAF00000188575 | bam | 328.9 MB | ||
| EGAF00000188576 | bam | 321.8 MB | ||
| EGAF00000188577 | bam | 249.8 MB | ||
| 12 Files (3.3 GB) | ||||