Investigating low frequency variants in CAD/MI cases, controls and pedigrees using whole exome sequencing and custom pulldowns
The Cardiogenics re-sequencing study will consist of three parts: Eight pools of 25 individuals will be sequenced using a Nimblegen hybrid-capture solution specific to miRNA sequences, 80 pools of 25 individuals will be sequenced using a custom Agilent SureSelect array covering genes associated with coronary artery disease (CAD) and myocardial infarction (MI), 10 individuals from families with a history of CAD/MI will be exome sequenced using the Sanger exome array. The experiment will use the early onset patients from the German MI cohort and the UK BHF CAD/MI cohort both of which have strong family history. For controls we will consider individuals from the UKBS and KORA cohorts.
- 28/04/2017
- 12 samples
- DAC: EGAC00001000103
- Technology: Illumina HiSeq 2000
Wellcome Trust Sanger Institute Data Sharing Policy
https://www.sanger.ac.uk/datasharing/
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| Other |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Located in | |
|---|---|---|---|---|
| EGAF00000078915 | bam | 13.4 GB | ||
| EGAF00000078916 | bam | 12.7 GB | ||
| EGAF00000078917 | bam | 12.9 GB | ||
| EGAF00000078918 | bam | 13.2 GB | ||
| EGAF00000078919 | bam | 13.3 GB | ||
| EGAF00000078920 | bam | 13.4 GB | ||
| EGAF00000078921 | bam | 13.6 GB | ||
| EGAF00000078922 | bam | 17.2 GB | ||
| EGAF00000078923 | bam | 16.1 GB | ||
| EGAF00000078924 | bam | 17.1 GB | ||
| EGAF00000078925 | bam | 17.0 GB | ||
| EGAF00000081183 | bam | 14.4 GB | ||
| 12 Files (174.4 GB) | ||||