DAC: RNAseq Iron-Treated iPSC-derived Microglia

Willeke M.C. van Roon-Mom
w.m.c.van_roon@lumc.nl

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Dataset ID	Description	Technology	Samples
EGAD00001008660	Iron accumulation in microglia has been observed in Alzheimer’s disease and other neurodegenerative disorders and is thought to contribute to disease progression through various mechanisms including neuroinflammation. To study the interaction between iron accumulation and inflammation, we treated human induced pluripotent stem cell-derived microglia (iPSC-MG) with an increasing concentration of iron, in combination with inflammatory stimuli such as interferon gamma and amyloid β, and performed RNA sequencing.	Illumina NovaSeq 6000	24