Projects
Jointly managed by the European Bioinformatics Institute (EMBL-EBI) in Cambridge (UK) and the Centre for Genomic Regulation (CRG) in Barcelona, the EGA provides an invaluable service to the worldwide biomedical research community. The teams leading the EGA are involved in several international partnerships and consortia in numerous scientific fields, where they contribute to ambitious projects. In addition to the project listed below, The EGA is in a long-standing partnership with the Global Alliance for Genomics & Health (GA4GH), as described on the dedicated page.
On-going projects
| Project | Duration | Domain | Funder | Tags |
|---|---|---|---|---|
| EUCAIM | EUropean Federation for CAncer IMages is a project that will build a highly secure, federated and large-scale European cancer imaging platform, with capabilities that will greatly enhance the potential of Artificial Intelligence in oncology. | 2023-2027 | Cancer | Digital Europe Programme (DIGITAL) |
DISCOVERY
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| Youth-GEMs | Youth-GEMS (Gene Environment Interactions in Mental Health TrajectorieS of Youth) will conduct research into the genetic and environmental factors of mental health in young European people. | 2022-2027 | Mental health | European Commission - Horizon Europe |
DATA MANAGEMENT
DISCOVERY
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| GDI | The European Genomics Data Infrastructure project is enabling access to genomic and related phenotypic and clinical data across Europe. It is doing this by establishing a federated, sustainable and secure infrastructure to access the data. | 2022-2026 | Not applicable | European Commission - Horizon Europe |
INFRASTRUCTURE
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| EOSC4Cancer | EOSC4Cancer builds on existing projects, research outcomes and established community solutions to create the federated FAIR data, analysis and services infrastructure needed for European Cancer research programmes. | 2022-2025 | Cancer | European Commission - Horizon Europe |
DISCOVERY
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| EuCanImage | A European Cancer Image Platform Linked to Biological and Health Data for Next-Generation Artificial Intelligence and Precision Medicine in Oncology. | 2020-2024 | AI Solutions in Oncology | European Commission - H2020 Programme |
DATA MANAGEMENT
METADATA STANDARDS
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| GenoMed4ALL | A consortium built to empower personalised medicine in the field of haematological diseases through the use of AI and the pooling of genomic and clinical data. | 2020-2024 | Not applicable | European Commission - H2020 Programme |
DISCOVERY
METADATA STANDARDS
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| IMPaCT-T2D | The IMPaCT-T2D project aims at studying the complete genomes of a large cohort of patients with Type 2 Diabetes mellitus (T2D), using modern sequencing technologies and artificial intelligence (AI) in order to improve the stratification and pharmacological treatment in the context of precision medicine. | 2022-2025 | Cardiovascular and Complex Diseases | Spanish Ministry of Science and Innovation; Instituto de Salud Carlos III |
ACCESS
DATA MANAGEMENT
DISCOVERY
INFRASTRUCTURE
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| IMPaCT-Data | IMPaCT-Data aims to create the infrastructure for secondary use of data from Spanish healthcare systems - electronic health records, medical imaging and genomic repositories - and contribute with the knowledge and methodology produced to the healthcare system. | 2021-2024 | Large-scale genomics and health data | Spanish Ministry of Science and Innovation; Instituto de Salud Carlos III |
ACCESS
DATA MANAGEMENT
DISCOVERY
INFRASTRUCTURE
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| LaMarató | It is a project aimed at creating and developing a catalan interhospitalary network to interrogate genetic variants from thousands of genetic tests carried out in patients with rare diseases from the main catalan hospitals. | 2021-2024 | Genomic and health data | Fundació La Marató de TV3 (catalan foundation) |
DISCOVERY
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| PPCG | The Pan Prostate Cancer Group aims to harmonise and interrogate Whole Genome DNA Sequence data generated around the world from over 2000 men with prostate cancer, with associated transcriptome and methylome data to include men from different clinical categories, and ethnicities. This project is about providing breakthrough advances through analysis of a very large series of Whole Genome DNA data from prostate cancer contributed by many of the leading scientists and clinicians working in prostate cancer genomics. | 2019-2024 | Cancer | Cancer Research UK |
DATA MANAGEMENT
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| Solve-RD | Solve-RD - solving the unsolved rare diseases - is a research project funded by the European Commission. It echoes the ambitious goals set out by the International Rare Diseases Research Consortium (IRDiRC) to deliver diagnostic tests for most rare diseases by 2020. The current diagnostic and subsequent therapeutic management of rare diseases is still highly unsatisfactory for a large proportion of rare disease patients - the unsolved RD cases. For these unsolved rare diseases, we are unable to explain the etiology responsible for the disease phenotype, predict the individual disease risk and/or rate of disease progression, and/or quantitate the risk of relatives to develop the same disorder. | 2018-2024 | Rare diseases | European Commission - H2020 Programme |
ACCESS
DATA MANAGEMENT
METADATA STANDARDS
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| EBV-MS | “Targeting Epstein-Barr Virus Infection for Treatment and Prevention of Multiple Sclerosis”. The ambitious goals of the project are to answer the questions why only a few EBV infected persons develop MS, and define the underlying mechanism of this process, as well as clarify if targeting the EBV infection can prevent MS or improve the disease course. | 2023-2028 | Viral-host genetics, Immune response, Disease modelling, Disease prevention | Horizon Europe |
DATA MANAGEMENT
DATA ANALYSIS
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| WISDOM | WELL-BEING IMPROVEMENT THROUGH THE INTEGRATION OF HEALTHCARE AND RESEARCH DATA AND MODELS WITHOUT BORDER FOR CHRONIC IMMUNE-MEDIATED DISEASES aims to deploy novel approaches for data processing, harmonisation, management, and secure data sharing and federated access for diseases like multiple sclerosis. Using an end-user guided approach, it will facilitate responsible and critical assessment of the use of AI in healthcare. | 2023-2028 | Chronic immunie-mediated diseases | Horizon Europe |
DATA MANAGEMENT
INFRASTRUCTURE
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| HEREDITARY | HEREDITARY aims to transform the way we approach disease detection, prepare treatment response, and explore medical knowledge by building a robust, interoperable, trustworthy, and secure framework that integrates multimodal health data (including genetic data) while ensuring compliance with cross-national privacy-preserving policies. | 2024-2027 | Neurodegenerative disorders, gut-brain interplay | Horizon Europe |
DATA MANAGEMENT
DATA ANALYSIS
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| EOSC-ENTRUST| The mission of EOSC-ENTRUST is to create a European network of trusted research environments for sensitive data and to drive European interoperability by joint development of a common blueprint for federated data access and analysis. | 2024-2026 | Trusted Research Environment | Horizon Europe |
INFRASTRUCTURE
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Completed projects
| Project | Duration | Domain | Funder | Tags |
|---|---|---|---|---|
| IHCC | The International HundredK+ Cohorts Consortium aims to create a global platform for translational research – informing the biological and genetic basis for disease and improving clinical care and population health. | 2020-2022 | Translational research | NIH; The Wellcome Trust; CZI |
INFRASTRUCTURE
METADATA STANDARDS
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| VEIS | The core mission of VEIS is to create an open ecosystem of technologies that will address and adapt to the requirements of the systems used to analyse and interpret -omics and clinical data in research and application environments in biomedicine. The aim of the project is to leverage the value of the EGA for both industry and society. | 2019-2022 | Oncology and Rare diseases | Generalitat de Catalunya and European Regional Development Fund (ERDF) |
ACCESS
DISCOVERY
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| ELIXIR BEACON IS | This study follows on from a number of earlier activities that have established the ELIXIR Beacon Project. The main aim is to extend the Beacon protocol, developed at EGA, to become the reference ELIXIR Data Discovery product | 2019-2021 | Not applicable | ELIXIR | DISCOVERY |
| ELIXIR FHD IS | This project coordinates the delivery of FAIR compliant metadata standards, interfaces, and reference implementation to support the federated ELIXIR network of human data resources. | 2019-2021 | Human genomic data | ELIXIR |
INFRASTRUCTURE
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| ELIXIR Rare Disease | The Rare Disease Community extends and generalises the system of access authorisation and high volume secure data transfer developed within the EGA. The goal of the Community is to create a federated infrastructure that will enable researchers to discover, access and analyse different rare disease repositories across Europe. It is doing this in partnership with other European infrastructure projects, namely RD-CONNECT, BBMRI-ERIC and E-Rare. | 2019-2021 | Rare diseases | ELIXIR |
INFRASTRUCTURE
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| ELIXIR-CONVERGE | An alliance with the goal of Connecting and aligning ELIXIR Nodes to deliver sustainable FAIR life-science data management services. | 2020-2023 | Data Management and Infectious Diseases | European Commission - H2020 Programme |
DATA MANAGEMENT
INFRASTRUCTURE
METADATA STANDARDS
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| CINECA | Consortium providing a Federated solution enabling population-scale genomic and biomolecular data accessible across international borders accelerating research and improving the health of individuals resident across continents. | 2019-2023 | Large-scale Genomics and Health Data | European Commission - H2020 Programme |
ACCESS
DATA MANAGEMENT
DISCOVERY
INFRASTRUCTURE
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| EASI-Genomics | A project designed to provide easy access to cutting-edge DNA sequencing technologies to researchers from academia and industry, within a framework that ensures compliance with ethical and legal requirements, as well as FAIR and secure data management. | 2019-2023 | Next Generation Sequencing | European Commission - H2020 Programme |
ACCESS
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| EuCanShare | An EU-Canada joint infrastructure for next-generation multi-Study Heart research. | 2018-2022 | Cardiovascular Diseases | European Commission - H2020 Programme |
ACCESS
METADATA STANDARDS
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| EUCANCan | A federated network aiming at implementing a cultural, technological and legal integrated framework across Europe and Canada, to enable and facilitate the efficient sharing of cancer genomic data. | 2019-2023 | Cancer | European Commission - H2020 Programme |
DATA MANAGEMENT
METADATA STANDARDS
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| B1MG | Beyond 1 Million Genomes aims to create a network of genetic and clinical data across Europe. The project provides coordination and support to the 1+ Million Genomes Initiative (1+MG). This initiative is a commitment of 24 EU countries, the UK and Norway to give cross-border access to one million sequenced genomes by 2022. | 2020-2023 | Not applicable | European Commission - Horizon Europe |
DATA MANAGEMENT
INFRASTRUCTURE
METADATA STANDARDS
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| EJP-RD | An European consortium built to create a comprehensive, sustainable ecosystem allowing a virtuous circle between research, care, and medical innovation. | 2019-2023 | Rare diseases | European Commission - H2020 Programme |
ACCESS
DATA MANAGEMENT
DOCUMENTATION
METADATA STANDARDS
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| The Federated EGA framework: supporting sensitive data management across the ELIXIR Nodes | This project is a direct continuation of the FHD IS with the goal to position the FEGA framework as the core infrastructure driver to support human data sharing for research. | 2019-2023 | Human genomic data | ELIXIR |
INFRASTRUCTURE
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| UK Biobank | UK Biobank is a large-scale biomedical database and research resource, containing in-depth genetic and health information from half a million UK participants. This project is to archive whole genome sequencing and other genetic data for UK Biobank participants. | 2019-2023 | Large-scale Genomics and Health Data | The Wellcome Trust; UKRI; Amgen; AstraZeneca; GSK; Johnson & Johnson |
DATA MANAGEMENT
INFRASTRUCTURE
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| HealthyCloud | This consortium will contribute a Strategic Agenda towards the European Health Research and Innovation Cloud. The project will work in collaboration with a broad range of stakeholders to ensure that all voices are included and that the results are technically and ethically sound. | 2021-2023 | Not Applicable | European Commission - H2020 Programme |
DOCUMENTATION
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| EOSC-Life | EOSC-Life brings together the 13 Life Science research infrastructures (LS RIs) to create an open, digital and collaborative space for biological and medical research. The project will publish 'FAIR' data and a catalogue of services provided by participating RIs for the management, storage and reuse of data in the European Open Science Cloud (EOSC). | 2019-2023 | Not applicable | European Commission - H2020 Programme |
DOCUMENTATION
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| BY-COVID | The BeYond-COVID project aims to make COVID-19 data accessible to scientists in laboratories but also to anyone who can use it, such as medical staff in hospitals or government officials. Going beyond SARS-CoV-2 data, the project will provide a framework for making data from other infectious diseases open and accessible to everyone. | 2021-2024 | Infectious diseases | European Commission - H2020 Programme |
ACCESS
DATA MANAGEMENT
DISCOVERY
INFRASTRUCTURE
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